4 things that hurt the liver more than staying up late, the last one you will never think of
Liver: Vulnerable Warrior
When it comes to the liver, everyone is familiar with it.
Although the liver is an expert in detoxification and a safety guard, it does not mean that it is invulnerable and invulnerable.
In fact, the liver is a vulnerable warrior!
What hurts the liver the most? Talk to a hepatobiliary surgeon today.
Drinking heavily can harm the liver
As the saying goes, diseases come from the mouth, and most of the things that "hurt the liver" in daily life are also related to eating.
For example, alcohol is the culprit that hurts the liver.
Alcohol (ethanol) is metabolized in the liver first to acetaldehyde, then to acetic acid, and finally to water and carbon dioxide.
In this metabolic chain, the real damage to the liver is acetaldehyde. Acetaldehyde damage to the liver can be mild or severe:
If it is light, damage to liver cells causes liver enzymes (such as transaminases) to run from the cells into the blood, so many people will find that liver enzymes (transaminases) are elevated after drinking blood tests.
In severe cases, liver cells undergo irreversible damage and undergo a series of evolutions into "liver cirrhosis", medically known as "alcoholic cirrhosis", which may develop into liver cancer.
Eating large pieces of meat hurts the liver
Eating too much fat can also damage the liver.
The liver is the metabolic center of the three major nutrients in the human body: sugar, protein, and fat. After the food eaten in the stomach is digested by the gastrointestinal tract, it will be processed in the liver to transform the nutrients used by the adult body.
The liver is not made of iron, it can also be "tired".
If you eat big fish and meat and a heavy oil diet, the liver cannot handle it, and the fat cannot be metabolized into sugar in time. Instead, it acts as a stock and accumulates in the liver cells, causing damage. This situation is called "fatty liver".
Fatty liver can be treated and reversed to some extent, but if left untreated for a long time, it can cause fatty cirrhosis and even liver cancer.
Drug abuse, indiscriminate consumption, liver damage
The liver is a well-known "detoxification organ" that is involved in drug metabolism and can break down toxic substances.
If you pay attention to the "Adverse Reactions" column in the drug manual, you will find that quite a few drugs write a sentence: Long-term use may cause liver enzymes to rise, please take the medicine under the guidance of a doctor.
Therefore, do not take any medicine indiscriminately (including the so-called "tonic"), you must take it under the guidance of a doctor and follow the instructions.
"Liver protection, liver protection" products may also harm the liver
Many people will say when they see this: Drinking too much alcohol is not good for the liver. I can't bear it, but taking "hangover medicine", "liver protection medicine" and "liver protection medicine" is also harmful to the liver?!
Don't worry, there's a reason -
1. There is currently no "hangover" at all
Alcohol is mainly metabolized in the liver. In theory, it is necessary to speed up alcohol metabolism to hangover.
However, the rate of alcohol metabolism mainly depends on the activity of related enzymes, and there are currently no drugs that can significantly increase the activity of these enzymes.
2. Eating health products may also increase the burden on the liver
No matter what "liver protection" product it is, eating it also requires liver metabolism and increases the burden on the liver.
If the ingredients are known and the body can handle them, that's fine; if unclear and inappropriate ingredients are added, it is likely to cause liver damage.
Staying up late and liver health
I would like to add here the issue of "staying up late hurts the liver".
Although there is no definitive evidence that staying up late directly harms the liver, irregular sleep and lack of sleep do have some impact on the state of the liver (for example, abnormal bilirubin-related indicators will be found during physical examination).
If staying up late and sleeping late doesn't "directly hurt the liver", what will it hurt?
It doesn't hurt much, it only hurts the whole body. The liver is naturally not spared.
Therefore, it is also true that everyone wants to "protect the liver" by not staying up late and sleeping well.
To protect the liver, you only need 4 "points"
So, what should I do to protect my liver?
In fact, it is very simple to do the opposite of what was mentioned earlier:
1. Drink less: Drinking less alcohol is good for the liver, and everyone on earth should know it.
2. Be balanced: work and rest regularly, get enough sleep, eat a balanced diet, have enough nutrition but not too much, and keep exercising to control your weight.
3. Be simple: give up the idea of "eating something to nourish the liver" and not add extra burden to the liver.
4. Be careful with medication: do not take medicine casually, take medicine under the guidance of a doctor.
Finally, let's remind everyone not to forget to get the hepatitis B vaccine and have regular checkups.
During the Spring Festival, socialize a lot, do four "points", do a good job of prevention, and do not cause trouble to the liver. This is the most cost-effective and effective "maintenance".
News link: During the Spring Festival, don't drink alcohol while taking these medicines, otherwise you will die!
Eating medicine and drinking wine is a terrible thing!
You may not know that some medicines and wines are "mutually exclusive", which can increase the burden on the liver in some cases, and can cause liver necrosis, coma, and even death in others!
Therefore, be sure to remember the following medicines and never drink alcohol after taking them!
When someone persuades you to drink, just say "I'm sorry, I'm taking medicine".
These medicines are dangerous to take with alcohol!
Cold medicine + alcohol = liver failure
Most cold medicines contain acetaminophen (also known as paracetamol), which is used to treat colds, fevers and relieve pain. During the biotransformation of acetaminophen in the body, a toxic metabolite is produced, which needs to be combined with protective factors such as reducing glutathione in the body to reduce toxicity.
Excessive alcohol consumption consumes a large amount of glutathione in the body, causing the metabolite produced by acetaminophen to fail to bind to glutathione, increasing the risk of liver failure.
Cephalosporins + alcohol = poison
Cephalosporin antibiotics plus alcohol are equivalent to poison, because the main component of alcohol is ethanol, which is first converted into acetaldehyde when entering the body, and then converted into water and carbon dioxide under the action of enzymes.
And cephalosporins will inhibit the conversion and excretion of acetaldehyde. Excessive accumulation of acetaldehyde can lead to facial and systemic skin flushing, nausea, vomiting, headache, dizziness, chest tightness, heart palpitations, blurred vision, abdominal pain, diarrhea, shortness of breath, sweating and other symptoms, and even severe symptoms such as blood pressure drop, breathing difficulties, acute heart failure, myocardial infarction, and shock.
The onset of the drug can take 5 to 10 minutes after drinking alcohol, and the reaction lasts for 30 minutes to several hours. In severe cases, it can even be fatal.
Hypotensive drugs + alcohol = hypotensive shock
Drinking alcohol while taking blood pressure lowering drugs such as risepine, captopril, heartacodine, nifedipine, hydrazidazine, and dibazole may cause vasodilation, resulting in hypotensive shock, which can be life-threatening in severe cases.
Because alcohol has the effect of dilating blood vessels, inhibiting sympathetic nerves and myocardial contractility, it can enhance the effect of antihypertensive drugs, causing headaches and even shock. Some antihypertensive drugs such as compound antihypertensive tablets and compound dihydralazine combined with alcohol may also cause a sharp increase in blood pressure.
Angina + Alcohol = Headache, Shock
Anti-angina drugs such as isosorbide nitrate, nitroglycerin, and nifedipine, if consumed during the medication, can cause excessive dilation of blood vessels, leading to severe headaches, sudden drops in blood pressure, and even shock.
Antipyretic and analgesic drugs + alcohol = gastrointestinal bleeding
Antipyretic and analgesic drugs include aspirin, ibuprofen, diclofenac, etc. If you drink a lot of alcohol while taking such drugs, it can cause the gastrointestinal mucosa to be stimulated by both drugs and ethanol, and even cause peptic ulcers or bleeding.
Hypoglycemic drugs + alcohol = hypoglycemic shock
During the use of hypoglycemic drugs such as Youjiangtang, Jiangtangling, Toluenesulfonylurea, Glibenclamide, Metformin, Insulin, etc., alcohol should not be consumed at the same time, because alcohol has the effect of enhancing the efficacy of these drugs. When the two meet, they can cause dizziness, palpitation, cold sweating, hand shaking and other hypoglycemic reactions. In severe cases, hypoglycemic shock can occur, which is life-threatening.
Sleeping pills + alcohol = one life
Diazepam, Nitrazepam, Clonazepam, Triazolam, Barbiturates, and Chloral Hydrate and other sedative and hypnotic drugs have certain effects on breathing and heartbeat. Alcohol also has the same effect. The combination of the two can produce double stimulation, which can make people unresponsive, lethargic, or even unconscious. The respiratory and circulatory centers will also be suppressed, and the breathing will slow down, blood pressure will drop, shock, and even stop breathing and die.
Antiepileptic drugs + alcohol = drug failure
Long-term alcohol consumption can reduce the concentration and efficacy of anti-epileptic drugs (such as phenytoin sodium). If you drink alcohol at the same time or shortly after taking the drug, the effect of the drug will be lost rapidly, which will greatly reduce the therapeutic effect and lead to difficult control of seizures.
Allergy medication + alcohol = drowsiness and coma
Diphenhydramine (e.g. prednisone), chlorpheniramine (e.g. chlorpheniramine), and Xegendine taken with alcohol can cause drowsiness, trance, and coma. Therefore, alcohol should be avoided during the use of second-generation antihistamines, otherwise the risk of adverse reactions will be significantly increased.
In addition, it should not be taken by people who drive vehicles, work at heights, etc., who require high concentration.
Gastroenteritis medicine + alcohol = easier to get drunk
Dysenterin (Furazolidone Tablets) is mainly used for some people with bad stomach, such as bacterial dysentery, enteritis, etc. After taking the medicine, the gastrointestinal discomfort can be relieved quickly, but if you drink some wine at this time, you will feel drunk faster than usual, thirst, dizziness, flushing of the skin on the face and body, panic, and appear drunk.
Dysenterin not only has antibacterial effects, but also is a monoamine oxidase inhibitor. After taking it, hydroxyethylamine metabolites are generated in the intestines, which enhances the body's sensitivity to alcohol. Therefore, even if you only drink a small amount of alcohol, it is easy to lead to intoxication. Therefore, it is forbidden to drink alcohol when taking Dysenterin tablets. If you have stopped taking the drug, you should only drink alcohol after stopping the drug for half a month, otherwise you can still experience symptoms of intoxication. Because the monoamine oxidase activity in the body inhibited by Dysenterin will gradually return to normal levels after two weeks of stopping the drug.
Warm reminder
Do not drink alcohol during the period of taking the medicine and for two weeks after stopping the medicine, and also pay attention to avoid some foods or medicines containing alcohol, such as wine heart chocolate, Huoxiang Zhengqi water, alcoholic beverages, etc.