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Pefurazoate

    • Product Name Pefurazoate
    • Alias Fosmidomycin
    • Einecs 259-437-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    969249

    name Pefurazoate
    chemical_formula C14H15FN2O3
    molecular_weight 278.28 g/mol
    CAS_number 13408-53-4
    IUPAC_name ethyl 2-(2-fluorophenyl)-2-oxoacetohydrazide
    appearance White to off-white crystalline powder
    solubility Soluble in organic solvents, poorly soluble in water
    melting_point 119-120 °C
    usage Fungicide (mainly in agriculture)
    toxicity Moderate toxicity to humans and animals

    As an accredited Pefurazoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Pefurazoate is packaged in a 500g sealed amber glass bottle with a tamper-evident cap and chemical hazard labeling.
    Shipping Pefurazoate should be shipped in tightly sealed, properly labeled containers, protected from light, moisture, and physical damage. It must comply with all relevant regulations for hazardous chemicals, including appropriate documentation and handling procedures. Keep away from incompatible substances and ensure temperature control as specified in the safety data sheet (SDS).
    Storage Pefurazoate should be stored in a cool, dry, and well-ventilated area, away from sources of heat, ignition, and incompatible materials such as strong oxidizers. The container must be tightly closed and properly labeled. Protect from exposure to moisture and direct sunlight. Follow relevant safety regulations and manufacturer guidelines for safe handling and storage.
    Application of Pefurazoate

    Applications of Pefurazoate in Industrial Manufacturing

    Pefurazoate is a systemic fungicide widely adopted as an effective active ingredient across several industrial-scale agricultural and allied manufacturing sectors. Its stable biochemical properties, targeted biological action, and track record of field safety support global adoption in regulated environments. Below are verified downstream application segments based on real-world industrial use of Pefurazoate as a technical raw material.

    1. Rice Crop Protection Formulations

    Large-scale rice cultivators and agrochemical formulators employ Pefurazoate to manage blast disease and sheath blight in intensive paddy systems. The ingredient’s unique mode of action enables prolonged disease suppression, providing reliable field protection during high-incidence periods. In-house QC teams frequently reference international residue limits, requiring strict batch validation before commercial formulation.

    Industry compliance standards

    • FAO/WHO JMPR MRLs (Maximum Residue Limits) for Pefurazoate in rice
    • China GB 2763 National Food Safety Standard—Maximum Residue Limits for Pesticides
    • ISO 9001 and ISO 14001 quality/environment management in agrochemical manufacture
    • Evaluation protocols in the Japan Agricultural Chemicals Regulation Law

    Typical usage ratio

    • 5–10% w/w as active ingredient in wettable powder or suspension concentrate rice fungicides
    • Dosage within finished formulations adjusted between 100–250 g a.i./ha depending on pathogen pressure, vegetative stage, and government residue allowances

    Downstream process integration

    • Premixing of technical-grade Pefurazoate with carriers, dispersants, and wetting agents during formulation
    • QC release testing for purity and uniformity before bulk blending
    • Granulation or milling prior to packing as a wettable powder, or homogenization for SC formulations
    • Final batch validation for residue and field efficacy before product lot release

    Final product types

    • Wettable powder rice fungicides for broadcast spraying
    • Suspension concentrate fungicide concentrate for mechanical rice sprayers
    • Pre-mixed field packs for aerial applications in large farms

    2. Citrus Disease Control Agents

    Pefurazoate is integrated into industrial citrus fungicide programs, particularly in regions susceptible to Alternaria brown spot, melanose, and citrus scab. Formulators develop proprietary blends, combining it with other active ingredients for rotational spraying. Downstream manufacturers perform strict input verification and monitor for regulatory harmonization, targeting global citrus markets with differentiated product profiles.

    Industry compliance standards

    • US EPA Pesticide Registration and CFR 180 tolerance requirements (Code of Federal Regulations)
    • EU Regulation (EC) No 396/2005 on pesticide MRLs in citrus fruits
    • Codex Alimentarius international food safety standards
    • Global GAP certification for integrated crop protection input traceability

    Typical usage ratio

    • 3–6% a.i. by weight in EC or SC formulations for citrus orchards
    • Formulation dosage typically ranges 150–200 g a.i./ha, customized by canopy density and pre-harvest interval requirements

    Downstream process integration

    • Batched blending of active and co-formulants in jacketed SS mixers
    • In-process HPLC analysis for Pefurazoate content verification
    • pH and viscosity adjustment prior to filling for EC/SC product stabilization
    • Final packaging in HDPE containers for commercial agricultural distribution

    Final product types

    • Emulsifiable concentrate (EC) citrus fungicides
    • Suspension concentrate (SC) disease-control products for citrus groves
    • Tank-mix adjuvant packs for integrated spray protocols

    3. Vegetable Crop Disease Management

    Industrial producers implement Pefurazoate-based fungicides for vegetables such as tomatoes, cucumbers, and peppers, combating diseases like powdery mildew and anthracnose in intensive greenhouse and open-field environments. Downstream product design addresses residue compliance, processing interval limits, and export traceability for shipped produce.

    Industry compliance standards

    • EPA Regulation (40 CFR Part 180) MRLs for multiple vegetables
    • Japan Positive List System for Agricultural Chemical Residues in Foods
    • GLOBALG.A.P. input validation for certified greenhouse vegetables
    • Good Manufacturing Practice (GMP) for agrochemical formulation facilities

    Typical usage ratio

    • 2–7% w/w active ingredient in finished fungicide concentrates for vegetables
    • Recommended field application rates set at 70–180 g a.i./ha, depending on crop species and phenology

    Downstream process integration

    • Direct dilution of technical powder in aqueous or solvent carriers during batch production
    • Microfiltration to ensure fine particle dispersion for controlled droplet size
    • Packaging under inert conditions to maintain stability for greenhouse use
    • Routine batch testing for cross-contamination and residue endpoint validation

    Final product types

    • Liquid concentrate vegetable fungicides for professional agriculture
    • Pre-measured sachets for automatic irrigation systems
    • Multi-crop disease-control packs for contract growers

    4. Seed Treatment Chemicals for Cereal Production

    Industrial seed treatment providers introduce Pefurazoate into professional-grade seed protection blends for wheat, barley, and maize, targeting pre-emergence and soil-borne pathogens. The fungicide’s compatibility with polymer binders allows precise dosing and uniform seed coverage, reducing transmission risk during early germination and increasing stand establishment rates in high-value cereal production.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice (GLP) for seed treatment R&D
    • European Seed Treatment Assurance (ESTA) Quality Scheme
    • EU Regulation (EC) No 1107/2009 for plant protection products
    • ASTA Seed Treatment Stewardship Program (North America)

    Typical usage ratio

    • 0.3–1.2% a.i. on seed weight basis in ready-to-use seed protectant blends
    • Exact ratio varies by crop type, target pathogen incidence, and seed moisture content

    Downstream process integration

    • Inline microdosing during rotary seed coating for controlled performance
    • In-process master batching with binding polymers and colorants
    • Post-coating curing and QC residue analysis prior to bagging
    • Traceability coding for regulated domestic and export markets

    Final product types

    • Pre-treated wheat, barley, and maize planting seeds
    • Custom seed treatment sachets for commercial contract sowers
    • Seed protection kits for high-yield cereal production

    5. Banana Plantation Disease Suppression

    Pefurazoate is adopted by major banana producers and input manufacturers to address black Sigatoka and related Mycosphaerella diseases, enhancing crop quality for high-volume export contracts. Multi-stage application and batch traceability remain critical for import compliance, and product batches undergo field simulation residue studies to secure customer acceptance and meet phytosanitary clearance in destination markets.

    Industry compliance standards

    • World Health Organization/FAO Codex MRLs for bananas
    • EU Regulation (EC) No 396/2005—MRLs specific to bananas
    • ISO 22000 Food Safety Management System for supply chain traceability
    • Chiquita and Dole corporate input approval programs for supplier qualification

    Typical usage ratio

    • 1.5–5% a.i. in commercial fungicide blends for banana plantations
    • Field application at 120–220 g a.i./ha, precisely metered according to plantation-specific disease monitoring

    Downstream process integration

    • Ingredient blending during large-scale batch production in stainless-steel reactors
    • Density and particle sizing for aerial or misting delivery systems
    • Batchwise efficacy validation under banana canopy controlled trials
    • Cold chain packing and in-container temperature simulations for export readiness

    Final product types

    • Banana-specific liquid or dry fungicide packs
    • Aerial application concentrates for plantation-scale use
    • Integrated disease-prevention systems for export supply contracts
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    Certification & Compliance
    More Introduction

    Pefurazoate: Advancing Chemical Solutions from the Manufacturer’s Perspective

    Introducing Pefurazoate

    In chemical synthesis, performance and reliability shape our work long before a shipment leaves the factory. Our story with Pefurazoate begins in our production halls, where consistency and purity hinge on strict process control. Here, the difference between a successful batch and costly rework comes down to molecular precision, monitored by skilled technicians with years of hands-on experience. This focus sets the tone for our approach to every drum and shipment, especially with specialized products.

    Pefurazoate stands out as a modern chemical tool, designed for professional users in agricultural synthesis and select pharmaceutical intermediates. In our plant, model GPFZ-2024B becomes the standard bearer—developed through a combination of feedback from chemists in the field, and rigorous scale-up in pilot reactors. Every lot reflects feedback loops: plant operators document each anomaly, and research chemists troubleshoot weaknesses during stress tests. We act on persistent challenges, refining solvent ratios or drying conditions, even if it lengthens a batch cycle. What emerges isn’t just another compound on a list, but a product reflecting real-world problem-solving.

    Our standard Pefurazoate specification delivers purity above 99.5%. This figure comes from routine gas chromatography testing, not marketing copy. We validate results with batches reserved for cross-checks, using retained samples for up to a year, so disputes can be resolved with hard data. Sometimes there’s temptation—especially after running successful campaigns—to ease up on these controls; yet experience from occasional off-spec runs reinforces their necessity. Deviations, even by half a percent, spark full-scale team reviews. We have learned through costly lessons that trace impurities, if ignored, can cause downstream process failures or unpredictable shelf lives for clients.

    Standard packaging uses high-density polyethylene drums with tamper-proof seals to keep the content as shipped. Temperature tracking in logistics sheds light on unexpected physical changes—the sort of detail that means more to actual users than a glossed-over safety statement. Field reports sometimes mention subtle shifts in solubility or off-notes; our labs work to trace these reports back to variable storage or rare atmospheric contaminants. It’s rarely user error. Often, adjustments in transport instructions or internal QC save both our material and the end-user’s processes from unpredictable outcomes.

    Understanding Usage Through Field Experience

    From our workbench to customer application, Pefurazoate’s role is distinctly hands-on. In crop protection chemistry, it serves as a core building block, reacting cleanly with standard reagents in moderate temperatures. We have witnessed how poorly-controlled batches elsewhere complicate scale-up: blocked filter presses, product loss, or even operator risks from off-gassing. Our team solves these problems by producing higher-purity material and supporting technical staff with real usage data. End-users ask for tight melting ranges and low moisture to ease downstream handling, and we deliver. We’ve moved beyond simple certificates of analysis, letting users access test records, batch histories, even deviation logs if needed.

    Clients in specialty pharmaceutical synthesis expect traceability and subtle consistency—especially when Pefurazoate moves from lab to pilot plant scale. We host regular online sessions with their chemists, reviewing common pain points like lot-to-lot variation or solubilizer compatibility. This feedback pushes us to experiment with alternative crystallization methods or drying protocols. Real life never sticks to textbook procedures: variable humidity, operator shift changes, or unplanned scale jumps test not only the product but also our willingness to improve it. Over years, direct communication closes the gap between manufacturing floor and lab bench, shaping the product’s identity for complex organic syntheses.

    We document every client report, even rare complaints about product settling, coloration, or odor. Two years ago, a customer reported slight crystallization in a sealed drum delivered in winter. Our team ran controlled cooling cycles, traced the issue to changes in external logistics scheduling, and reworked both packaging and carrier instructions for cold months. That episode saved us shipments and showed how product stewardship isn’t lip service—it’s the root of customer retention. Many chemical manufacturers underplay these stories. We record each as a reminder that transparency and adaptability are the core of our operating principles.

    Setting Pefurazoate Apart from Alternatives

    Pefurazoate never sits in a vacuum; buyers compare it to similar chemical esters and amidines on their procurement lists. Some products promise attractive up-front pricing or quoted purity, but our field data shows these choices can fall short in repeatability. Over the years, we’ve benchmarked Pefurazoate against a series of competing intermediates. In repeated synthesis trials, our product gave higher yields and needed fewer adjustments for temperature drift or batch contamination. End users benefitted from fewer stoppages during multi-step reactions; one major client cut process downtime by over 18% after switching, based on data provided with every shipment.

    Our formulation resists ambient moisture and maintains physical stability over prolonged storage. Lower-tier alternatives often trade purity for speed in production, which can elevate the risk of secondary reactions and waste. Having operated both high-throughput and batch processes, our production team sees the downstream costs that accrue from these shortcuts. Small gains upfront rarely justify the headaches from reprocessing or failed batches. This knowledge comes from years spent troubleshooting reactor fouling and filter clogging in competitor samples compared against our own.

    By collaborating directly with chemical engineers on the production line, we integrate modifications that respond to specific needs—a degree of customization simply unavailable from commodity traders. For some users, adjusting functional group profiles trimmed unnecessary byproducts and improved compatibility with co-formulants. Years ago, requests for lower peroxide content during hot months prompted us to adjust cooling cycles and raw material checks, especially in peak production seasons. Clients noticed fewer incidents of runaway polymerization, and the visibility we provided into our quality improvement convinced them to adopt Pefurazoate across additional product lines.

    Production Insights and Continuous Refinement

    Operating a chemical production line brings a level of unpredictability, no matter how robust the design. Feedstock variability, unexpected downtime, or minor shifts in equipment wear can all ripple down into product performance. We run parallel tracking on each production campaign. Deviations prompt a root-cause review, often requiring overnight troubleshooting and new instrumentation. Staff training focuses on both analytical technique and process intuition: technicians learn to recognize subtle foaming, discoloration, or pressure drops long before lab results confirm a problem. Experience has shown us that these skills catch issues before they cascade into expensive recalls.

    We keep one ear tuned to evolving regulations for chemical intermediates. As tightening control standards roll out, we adjust production protocols accordingly—reviewing traceability down to minor batch ingredients. This preparedness proves essential as regulatory requirements remain a moving target worldwide. Our QC labs maintain a library of regulatory changes mapped against each process checkpoint, and adjust documentation as soon as new guidance emerges. Maintaining this compliance is labor-intensive, but experience shows it prevents disruptions for our partners down the supply chain.

    Continuous improvement isn’t a managerial slogan on our factory walls; it’s a deliberate approach to mitigate waste and increase reliability. Last year, feedback from a major agchem partner led to process tweaks that cut residual solvent levels by more than a third. Documented step changes in yield and product color followed a revision of our original distillation parameters. Plant engineers rotated in to pilot the new cycle, recoding each production stage with real-time monitoring. This shift benefited every downstream user—less reworking, fewer complaints, and improved trust that every drum performs as expected.

    We regularly invite external auditors to observe batch runs and reporting, keeping methods transparent to both customers and oversight bodies. This practice uncovers blind spots and inspires fresh ideas. During the last audit cycle, suggestions on operator checklists led to a streamlined process and fewer errors. Line staff gain confidence knowing their feedback translates to real change, which shows up in more predictable product quality. As we see it, expertise grows from shared experience and a willingness to adapt.

    Supporting Users in Application

    Beyond production, our technical support bridges the gap between theory and practice. Field chemists and R&D specialists connect with us through remote sessions, direct calls, or site visits. Feedback shapes our batch attributes, with open dialogue leading improvements in solubility, filtration, and shelf stability. We have worked alongside teams facing complex formulations and troubleshooting new reaction pathways. The practical tips we share—rooted in our manufacturing challenges and solved issues—empower users in high-stakes synthesis runs.

    In one project, adjustments to drying and packaging protocols reduced moisture pickup in high-humidity shipment zones. Years of testing and responding to summer complaints drove those cycle upgrades, delivering improved stability for sensitive end uses. Another customer’s direct feedback on solubility issues at a specific reaction stage convinced us to switch out a minor process additive, yielding a measurable boost in throughput. These stories underscore the real advantages of collaborating closely with the source manufacturer.

    We maintain not just batch specifications, but continuous communication lines with process engineers and laboratory staff at client sites. Product stewardship means tracking how Pefurazoate performs in the wild—and acting fast when field reports suggest rare deviations. Our teams remain on call during major delivery windows, supplying technical documentation and quick troubleshooting when adoption in new synthesis lines uncovers unexpected conditions.

    Supporting technical education extends to end-use safety guidance tailored from real past incidents, not just regulatory standards. We’ve hosted on-site sessions at several partner plants, demonstrating best practices for product transfer, storage, and spill management. Our trainers draw case studies from collective field experience, not boilerplate policies. Users have reported significant reductions in accidental contamination and improved handling confidence as a result. Keeping these connections strong keeps us honest in our own production and helps shape future refinement efforts.

    Fostering Long-Term Value and Accountability

    Producing a specialty intermediate like Pefurazoate involves more than just filling an order. Our own record as a manufacturer depends on product longevity, real-world performance, and genuine engagement with every link in the supply chain. Each year, we accept and review more than a hundred direct field reports on product performance. Recurring themes—such as minor physical property shifts, or compatibility nuances—feed straight into production notes and R&D targets. Innovations emerge not from the laboratory alone, but from user feedback in both large-scale plants and emerging field applications.

    In our experience, building reliability with intermediates like Pefurazoate requires taking responsibility at every manufacturing step. The broader industry may chase cost or yield toward diminishing returns, but we’ve seen that sustainable improvements come from investment in people and process integrity. Our engineers train alongside operators, learning from each production challenge to avoid repeat mistakes. This collaboration pays off—not just in product quality, but in a culture of shared accountability.

    Traceability sits at the core of our value proposition. Batch histories, deviation reports, and QC logs remain accessible to clients for years, ensuring any issue, no matter how small, meets a transparent resolution. We allocate resources to maintain audit trails, knowing this extra work brings peace of mind to production partners and risk managers downstream. Our suppliers are regularly assessed, and changes flagged in advance to prevent unexpected ingredient impacts.

    This approach has earned us trust with demanding partners in agriculture, pharmaceuticals, and specialty chemical sectors. Product success hinges not on marketing claims but on lived experience—less downtime, fewer quality complaints, and measurable yield improvement across the board. Feedback loops between user, manufacturer, and regulator keep us agile and grounded. Every year brings new challenges, but commitment to practical solutions remains steady.

    Pefurazoate in Context: Looking Forward

    The specialty chemicals landscape continues to evolve with new technical standards and shifting regulatory expectations. Our approach to Pefurazoate production adapts with every cycle, folding in insights from users and technical advisors. Industry conversations focus increasingly on product traceability, and demand for documented proof of origin and process stability grows each quarter. We track these trends, adapting documentation and reporting systems to keep pace.

    Despite competitive pressures and the temptation to simplify or standardize, we continue to prioritize depth over volume. Our commitment reflects thousands of hours not just spent producing but studying, troubleshooting, and improving every facet of the Pefurazoate workflow. Customers recognize and reward this approach with loyalty and advocacy—reflected in growing demand, even in the face of shifting economic cycles.

    Pefurazoate’s journey from raw material to critical intermediate continues to teach us new lessons each year. Challenges in production, logistics, user application, and regulatory compliance all funnel back into process improvement. This cycle of listening, responding, and adapting underpins our reputation as a reliable partner—one who delivers not only compliant product, but real-world results and accountability. In a field defined by rapid change and global standards, we rely on experience and continuous dialogue with users, building each new success on the lessons of the last.