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Metsulfuron‑methyl

    • Product Name Metsulfuron‑methyl
    • Alias Ally
    • Einecs 262-349-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    857170

    common_name Metsulfuron-methyl
    chemical_formula C14H15N5O6S
    IUPAC_name Methyl 2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoate
    CAS_number 74223-64-6
    molecular_weight 381.36 g/mol
    physical_state Solid (crystalline powder)
    appearance White to beige powder
    solubility_in_water 2.8 mg/L at 25°C
    melting_point 163-164°C
    mode_of_action Inhibitor of acetolactate synthase (ALS)
    toxicity_to_humans Low
    primary_use Herbicide
    pH_stability_range Stable at pH 5-7, less stable at higher pH
    logP 0.1
    vapor_pressure <1.3 x 10⁻⁷ mPa at 25°C

    As an accredited Metsulfuron‑methyl factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Metsulfuron-methyl is packaged in a sealed 100-gram foil pouch, labeled with safety instructions, batch number, and manufacturer's details.
    Shipping Metsulfuron‑methyl should be shipped in tightly sealed, properly labeled containers, away from incompatible substances. Transport must comply with local, national, and international regulations, typically as a non-hazardous material. Containers should be protected from moisture, physical damage, and extreme temperatures during shipping to ensure product stability and safety.
    Storage Metsulfuron-methyl should be stored in its original, tightly closed container in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, food, feedstuffs, and water supplies. Keep out of reach of children and unauthorized personnel. Store away from acids and strong oxidizing agents. Follow all local regulations and label instructions for safe chemical storage.
    Application of Metsulfuron‑methyl

    Applications of Metsulfuron‑methyl in Industrial Manufacturing

    Metsulfuron-methyl is a high-activity sulfonylurea herbicide widely adopted by professional agrochemical product manufacturers for selective control of broadleaf and certain grass weeds. Our production consistently meets advanced technical demands, supporting complex downstream formulations in crop protection. Below, we detail established industrial application scenarios, emphasizing compliance standards, commercial dosage frameworks, process integration, and output types.

    1. Cereal Crop Pre-Emergent Herbicide Formulations

    Major agricultural chemical formulators use metsulfuron-methyl as an active ingredient in selective herbicide blends for wheat, barley, oats, and rye. Its high crop selectivity and residual activity support large-scale pre-emergent and early post-emergent weed management programs, optimizing yield by reducing weed competition before crucial growth phases. The product enters blending tanks after other inert carriers and dispersants for uniform distribution and controlled release in downstream formulation plants.

    Industry compliance standards

    • FAO Specification 326/TC (Metsulfuron-methyl technical material)
    • ISO 9001:2015-certified process control systems
    • EU Regulation (EC) No 1107/2009 – Plant Protection Products
    • EPA 40 CFR Part 180.428 – USA Tolerance Exemptions

    Typical usage ratio

    • 0.2–0.4% w/w in SC (suspension concentrate) herbicide formulations; adjusted by target weed density and local agronomic practice

    Downstream process integration

    • Direct addition post base dispersion, followed by high-shear mixing and homogenization prior to packaging in bulk containers or retail units

    Final product types

    • Pre-emergent herbicide SCs (suspension concentrates)
    • WG (water-dispersible granules)
    • WP (wettable powder)

    2. Rice Paddy Selective Weed Control Products

    Specialty agrochemical producers incorporate metsulfuron-methyl in formulations targeting annual and perennial broadleaf and sedge weeds in irrigated rice fields. Its low volatilization and safe residue profile make it compatible with typical paddy agro-environmental restrictions. For granular and aqueous concentrate products, the material is metered into closed mixing reactors after adjuvant addition, ensuring rapid dispersibility critical for application uniformity in high-moisture environments.

    Industry compliance standards

    • Japan Agricultural Chemicals Inspection Station (JACIS) specifications
    • China GB 20810-2006 (Metsulfuron-methyl pesticide product standards)
    • ISO 9001:2015 GMP for pesticide manufacturing
    • China MOA pesticide registration and maximum residue limits (MRL)

    Typical usage ratio

    • 0.1–0.3% w/w in granule herbicide products; adjusted for application method and local regulatory MRLs

    Downstream process integration

    • Dry blending with carrier granules, followed by compression granulation and controlled drying in rotary drum or fluid bed systems

    Final product types

    • Granular rice paddy herbicides (GR, WG)
    • Low-volume SL (soluble liquid concentrates) for aerial or direct application

    3. Pasture and Rangeland Weed Management Compounds

    Manufacturers deploy metsulfuron-methyl for the formulation of liquid and granular products designed for broad-acre pastureland and rangeland reconditioning. The raw material enables extended weed suppression without harming desirable forage grasses, supporting sustainable grazing operations. The product enters batch mixing systems following premixing with wetting agents to ensure appropriate wetting and dispersion prior to field-ready granulation or bottling.

    Industry compliance standards

    • US EPA Registered Pesticide Establishment Number
    • USDA National Organic Program non-prohibited substances list (when co-formulated accordingly)
    • Australian APVMA Registration standards
    • Environmental Protection Act compliance on drift and runoff limitation

    Typical usage ratio

    • 0.15–0.35% w/w for dry granules, depending on weed species cluster and application area

    Downstream process integration

    • Suspended in water-based solutions with surfactants before drying and granulation for water-dispersible pellets

    Final product types

    • Dry broadcast granules for rangeland weed control
    • Soluble concentrate weed control products for pasture management

    4. Industrial Non-Crop Vegetation Control Solutions

    Professional vegetation management contractors and public works supply houses utilize metsulfuron-methyl-based herbicides for long-lasting control of unwanted plant growth along highways, railway embankments, and utility rights-of-way. The product supports reliable suppression across varied site conditions and enters the manufacturing sequence after technical surfactants for inclusion in low-volume industrial spray formulations.

    Industry compliance standards

    • Occupational Safety and Health Administration (OSHA) Hazard Communication Standard (29 CFR 1910.1200)
    • EPA label and re-entry interval regulations for industrial-use herbicides
    • Transport and packaging requirements: UN 3077 (Environmentally hazardous substances, solid, n.o.s)
    • REACH Annex XVII restrictions (where applicable in EU export)

    Typical usage ratio

    • 0.05–0.2% w/w in tank-mix concentrates for industrial vegetation management; formulation varies with spraying equipment capacity, target species, and intended persistence

    Downstream process integration

    • Metered dosing into continuous blending lines; followed by high-shear agitation with anti-drift agents and direct drum filling for industrial supply

    Final product types

    • Non-crop industrial-use liquid concentrates
    • Pre-mixed roadside weed control solutions
    • Long-residual granules for railway ballast and utility corridors

    5. Formulated Herbicide Products for Legume Crops

    Legume growers benefit from metsulfuron-methyl inclusion in selective herbicides targeted for soybeans, chickpeas, and peanuts, offering comprehensive suppression of difficult broadleaf and certain grass weed populations. The material gets introduced during post-dispersion blending, with strict control of particle size and dispersibility, which is crucial for selective application and minimizing phytotoxicity in legume fields.

    Industry compliance standards

    • Codex Alimentarius MRL (Maximum Residue Limit) standards
    • US EPA Section 24(c) Special Local Needs registrations for selective herbicides
    • Brazilian Ministry of Agriculture ANVISA pesticide product registration
    • GHS (Globally Harmonized System) labeling for agricultural chemicals

    Typical usage ratio

    • 0.08–0.22% w/w based on crop variety, expected application rate, and weed survey data in target region

    Downstream process integration

    • Post-cooling addition in dispersant systems, followed by precision micronization for uniform field distribution in selective spray or granule products

    Final product types

    • WP (wettable powder) and WG (water-dispersible granules) herbicides for legumes
    • Low-volume liquid selective herbicides for row crop sprayers
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    Certification & Compliance
    More Introduction

    Metsulfuron-methyl – A Field-Level View

    Introduction to Metsulfuron-methyl

    Over the past decades, metsulfuron-methyl has become a mainstay for many commercial growers and land managers working to control broadleaf weeds and certain grassy weeds among cereal crops, pasture, and non-crop land. Developed for post-emergence weed control, this sulfonylurea herbicide has changed the way crews approach spring and autumn weed management, putting less pressure on the environment and machinery than some older chemistries. Our plant began manufacturing metsulfuron-methyl at scale in response to this rising demand, leaning on close collaborations with agronomists and on-farm feedback to drive our formulation efforts.

    How Metsulfuron-methyl Works in Real Field Conditions

    Growers who've worked for years with older treatments often recall the sheer load of physical labor involved in controlling aggressive weeds before sulfonylurea chemistries came along. Today, metsulfuron-methyl operates as a selective, systemic herbicide. It works by inhibiting the acetolactate synthase (ALS) enzyme in targeted weeds, effectively blocking the synthesis of essential amino acids like isoleucine, leucine, and valine. Once treated, susceptible weeds generally stop growing and fade out, giving crops or pasture grass a better chance to access light, water, and nutrients. This effect can be observed as early as a few days after application, but complete weed control sometimes takes several weeks, depending on species, weather conditions, and plant stages.

    Product Forms and Specifications in Practice

    We manufacture metsulfuron-methyl as a technical concentrate, which is processed into wettable powder, water-dispersible granules, and sometimes as a dry flowable formulation. The most common grades we ship contain 60% to 70% active ingredient concentration. Field users value the lower moisture content and consistent particle size, which help operators measure and mix product with minimal clumping, even in humid shed conditions. Storage stability has been a frequent talking point at farm shows, especially for cooperatives investing in bulk orders for shared use.

    The actual model of product our factory produces features carefully refined granules that break down quickly in water, suited for use with most boom sprayers and hand-held equipment. This aspect matters to spraying contractors covering hundreds of hectares per season, since it reduces downtime and possible nozzle blockages. Unlike some older herbicides, metsulfuron-methyl needs only a small amount per hectare—usually between 4g to 8g of product, depending on label guidance and target species. Reduction in material handled every day translates to lower operator fatigue, less packaging waste, and better precision in meeting resistance management programs.

    On-the-Ground Usage—From Cereal Crops to Rangeland

    In practical terms, metsulfuron-methyl delivers best value in wheat, barley, oat, and pasture renovation. We see many requests from farm managers handling ryegrass, wild radish, burr medic, capeweed, dock, and a range of thistle species. Because metsulfuron-methyl exerts residual control in soil, coverage persists beyond the initial flush of weeds, saving application passes in wetter seasons or on properties running lean on labor.

    Mixing options remain an area of frequent experimentation among users. The herbicide blends well with other broadleaf weed treatments, such as MCPA, dicamba, or 2,4-D, which lets applicators tailor their spray tank to local weed spectrums. Metsulfuron-methyl also shows compatibility with some grass herbicides, although crew foremen and agronomists working with us always recommend a small-scale jar test before scaling up to field-wide treatments.

    The Differences Between Metsulfuron-methyl and Other Herbicides

    Anyone in crop protection knows every herbicide brings its own quirks and advantages. Metsulfuron-methyl stands out from older phenoxy herbicides and triazines by attacking weeds at a much lower application rate. Where 2,4-D and MCPA often require kilogram-level doses per hectare, metsulfuron-methyl controls tough perennials with only grams per hectare. Some see this as a key reason for reduced heavy chemical handling in sheds and a lighter load on farm budgets. Less active ingredient per application means smaller stockpiles of product for the same area.

    Unlike glyphosate—a non-selective, broad-spectrum compound used pre-harvest or non-crop areas—metsulfuron-methyl can be sprayed directly onto crops at the growth stages indicated on product labels without foliage damage. This selectivity simplifies application timing and safeguards crop yield potential, particularly during sensitive leaf and tiller development phases. In addition, metsulfuron-methyl’s environmental profile appeals to operators aiming to minimize off-target effects. Application at label rates does not control all grass weeds, so some mix with other grass herbicides for a broader effect.

    Unlike sulfonamide herbicides with less favorable breakdown profiles, properly manufactured metsulfuron-methyl leaves behind minimal residues in soil and water under typical farming conditions. Users working in rotational cropping systems report minimal plant-back issues with most subsequent crops, provided standard label intervals are observed. Certain vegetable crops still require longer plant-back periods, so timing and crop planning remain important. We regularly review field data with agronomists so that we can update technical bulletins if rotational concerns arise.

    Field-Proven Production Practices and Consistent Quality

    Manufacturing metsulfuron-methyl on a full scale involves more than simply following a recipe. Our team monitors every production stage, from raw material supply (ensuring purity on sulfonylurea intermediates) to particle-size analysis during granulation. We run every batch through stability testing and representative spray equipment before approving shipments. Insights from contract sprayers and bulk customers feed directly into process adjustments. For example, our experience shows that tighter controls on drying temperature keep the finished product free of sticky residues—a key cause of tank mix issues on warm, humid days.

    Customers often ask how we differ on quality assurance compared to aftermarket suppliers or repackers. Over the years, we invested in advanced sieving and anti-caking processing, which means fewer nozzle plugs and consistent field rates. This reliability grows more important as application windows tighten due to shifting rainfall patterns or increased wind events—conditions many Australian and North American growers face each year.

    Environmental Factors in Responsible Use

    As regulatory attention around chemical runoff increases, we've focused on feedback from researchers and conservation groups. Metsulfuron-methyl carries a low risk of groundwater leaching when used as directed. The product binds strongly to organic matter, which restricts movement in soil and protects nearby waterways during heavy downpours. In our experience, growers who calibrate buffer zones and avoid overspraying along creek banks or wetlands report few aquatic impacts. In most climates, microbial communities break down metsulfuron-methyl in a matter of weeks to months, depending on moisture and soil activity.

    Drift management stands out as a concern, especially in mixed farming regions or where sensitive crops grow nearby. We work with customers to provide application tips—using drift-reducing nozzles, spraying under calm conditions, and adjusting boom height. Consistent advice and hands-on troubleshooting during busy spray seasons keep this issue manageable.

    Resistance Management—A Shared Challenge

    Repeated use of any herbicide without rotation risks the rise of resistant weed populations. Cases of ALS-inhibitor resistance (the mode of action in metsulfuron-methyl) have surfaced in several regions, including parts of Europe, North America, and Australia. Farms running tight rotations with high chemical pressure on target weed populations notice resistance can escalate in as little as five to ten years.

    We're proactive on resistance management, organizing field days and sharing tank-mix program examples. Rotating with other herbicide modes of action and utilizing non-chemical tactics—pasture rest, crop rotation, competitive cropping, and targeted grazing—goes a long way toward preserving metsulfuron-methyl’s effectiveness. In our own plant R&D, we screen alternations and residue profiles carefully to ensure label recommendations stand up to real-world pressures found on farms and in conservation land programs.

    Agronomic and Farmworker Safety in Practice

    Few aspects matter more to us than safety, both for operators and for those working livestock or harvesting from treated fields. Metsulfuron-methyl rates as practically non-toxic to mammals, but all mixing and spraying must respect label safety gear guidance—chemical-resistant gloves, goggles, and long-sleeved clothing. In our factory, bulk handlers follow similar measures. Ensuring clean-down and proper container disposal also protects workers, waterways, and livestock on properties using our product.

    Crop injury rarely results with label rates and proper mixing, but occasionally, low-lying fields with sandy soils see yellowing or stunting in young cereal crops, especially after cool, wet periods. We advise trialing new combinations on small plots before broad use, particularly with untested tank mixes or unfamiliar field histories. Staying in regular contact with agronomists gives farmers confidence and avoids costly re-sows.

    Real-World Economic Impact of Metsulfuron-methyl

    On the economics side, switching to metsulfuron-methyl usually results in reduced input costs for broadleaf weed control. Many growers point out the major savings come from fewer spray passes per season, less physical bulk to move around sheds, and more reliable knockdown. Unlike products that require tight post-rain timing or deep tillage, metsulfuron-methyl lets growers apply with more flexibility, often fitting into narrow working windows during busy planting or hay-cutting seasons.

    Our own experience working with large-scale broadacre farms as well as smaller mixed producers shows labor savings accumulate every year. When herbicide stocks and sprayer rigs do not need constant cleaning or recalibration, more time gets spent on higher-value tasks like crop scouting and livestock management. A steady product supply and knowledgeable support from the factory remain high priorities for us.

    Supporting Sustainable Farming Goals

    Sustainability extends beyond chemical profiles or manufacturing waste. Every year, we engage with farm groups working toward lower chemical footprints, higher soil health, and biodiversity goals. Metsulfuron-methyl fits well into reduced-till and conservation practices, making it suitable for those aiming to protect soil carbon, minimize run-off, and extend productive rotations.

    We encourage users to combine metsulfuron-methyl with tactics like cover cropping, precision spraying, and buffer strip establishment. These integrated approaches drive both short-term weed control and long-term soil stewardship. Information from on-farm research trials, field walks, and customer feedback feeds back into our own manufacturing and product stewardship initiatives.

    Innovation in Manufacturing for the Modern Grower

    Over time, the production of metsulfuron-methyl has shifted from meeting simple volume requirements to focusing on quality, granule handling, and end-user convenience. Our plant keeps up with regulatory developments, customer field reports, and market changes. By investing in particle size control, low-dust processes, and robust packaging, we help growers cut down on spillage and ensure safe, cost-effective use.

    The shift toward digital agriculture and traceability has prompted us to upgrade our labeling and batch tracking systems. Crop managers tracking herbicide loads per block, for audit or sustainability certification, rely on accurate product sourced directly from the manufacturer, rather than repackaged or relabeled stock.

    Adaptation to Changing Weed Pressure and Market Needs

    As weed spectrums shift due to climate and farming practices, the kinds of feedback we receive change as well. In wetter years, some customers report a wider range of broadleaf weeds surviving older chemistries, triggering a switch to metsulfuron-methyl as part of sequential programs. In drought years, product reliability and ability to perform at low water volumes become front of mind—a challenge we address through continuous improvement and collaboration with application technology specialists.

    Government programs promoting reduced off-target movement and “greener” chemistries have also impacted demand. Consistent supply, traceable origin, and technical clarity all play a part in which product gets chosen and kept on-farm. As a manufacturer, we maintain detailed technical documentation and transparency in sourcing, so every drum and bag our customers receive matches the expectations set at the research and agronomy levels.

    Ongoing Dialogue with the End User

    Every batch we manufacture carries the legacy of feedback—both praise and complaints—received from growers, sprayer operators, and input retailers over the years. As a chemical manufacturer, direct lines of communication are essential. We listen closely to experience-based recommendations: calls for finer granules, easier rinsing formulations, better shelf life in varied climates, or quicker customer support when things don’t go as planned.

    These relationships inform both formulation tweaks and process improvements at our plant, which means every production run incorporates learning from real-world use. Our technical representatives regularly visit farms during application season and gather data to inform future guideline updates or product releases.

    Conclusion—Why Metsulfuron-methyl Continues to Matter

    Years of field observation underscore that metsulfuron-methyl offers growers and land managers real control over a key risk—losses from tough weeds—without resorting to heavy chemical regimes or high environmental costs. Its low dose requirements, compatibility with integrated management, and adaptability to numerous crop and non-crop scenarios enable efficiency and sustainability.

    As expectations rise for transparent sourcing, consistent performance, and safety on every hectare, our focus remains firmly on quality assurance and open communication. From our factory floor to broadacre wheat fields and conservation reserves, every drum and bag of metsulfuron-methyl is shaped by the experience and commitment of those who rely on it season after season.