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HS Code |
600099 |
| CAS Number | 4955-66-0 |
| Molecular Formula | C12H12O |
| Molecular Weight | 172.23 g/mol |
| Appearance | Yellow crystalline solid |
| Melting Point | 72-74°C |
| Boiling Point | Approx. 340°C |
| Density | 1.06 g/cm³ |
| Refractive Index | 1.610 |
| Solubility | Slightly soluble in water, soluble in ethanol and organic solvents |
| Purity | Typically ≥98% |
| Synonyms | 4-Phenyl-3-buten-2-one, Cinnamylideneacetone |
| SMILES | CC(=O)C=CC1=CC=CC=C1 |
| Storage Conditions | Store in a cool, dry place, tightly closed |
| Flash Point | >110°C |
| Odor | Mild, pleasant |
As an accredited Cinnamylidene Acetone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Cinnamylidene Acetone, 25g, is packaged in a sealed amber glass bottle with a secure screw cap and clear labeling. |
| Shipping | Cinnamylidene Acetone should be shipped in tightly sealed containers, protected from moisture, heat, and direct sunlight. It must comply with local, national, and international regulations for chemical transport. Proper hazard labeling is required, and shipments should include safety documentation. Handle with care to avoid leaks or spills. |
| Storage | Cinnamylidene Acetone should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizing agents. Keep the container tightly closed and protected from light and moisture. Use appropriate chemical storage containers made from compatible materials, and label clearly. Follow relevant local regulations and material safety data sheet (MSDS) guidelines for storage. |
Applications of Cinnamylidene Acetone in Industrial ManufacturingCinnamylidene Acetone serves as a crucial intermediate for specialized downstream processes where its reactive double bond and aromatic character provide value in the synthesis of advanced industrial products. On this page, we outline our material’s real-world integration into four defined sectors, covering practical manufacturing information and application-specific compliance. 1. Synthesis of Flavor and Fragrance IntermediatesCinnamylidene Acetone functions as a core building block in the manufacture of aldehydic and spicy-type aroma chemicals used by fine fragrance, specialty flavors, and industrial scent formulation companies. Its conjugated enone structure participates directly in condensation and cyclization reactions, adding complexity to finished aroma molecules. Manufacturers apply precise dosing during the batch flavor synthesis stage to maintain both OECD and IFRA compliance, controlling side reactions and ensuring organoleptic purity for use in consumer products. Industry compliance standards
Typical usage ratio
Downstream process integration
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2. Fine Chemical Synthesis for Pharmaceutical IntermediatesPharmaceutical ingredient manufacturers utilize Cinnamylidene Acetone as a synthon in creating heterocyclic drug intermediates. The substituted enone acts as a Michael acceptor in multistep syntheses, enabling streamlined routes for high-purity custom pharmaceutical compounds. Reaction control, validated by in-line HPLC, remains essential for safety and regulatory acceptance, and all operations adhere to strict cGMP standards to support eventual API applications. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Specialty Polymer Additive ManufacturingIn the advanced polymers sector, Cinnamylidene Acetone is implemented as a reactive modifier to introduce crosslinkable aromatic vinyl groups within specialty coatings and resins. Its use targets UV-initiated crosslinking or thermal curing processes that require controlled functionalization for improved hardness and gloss retention. Formulators select the dosage based on the final mechanical property profile, and in-plant quality systems verify consistent dispersion. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Chemical Research and Analytical Reference StandardsResearch laboratories and analytical standards producers apply Cinnamylidene Acetone in method development and calibration for GC–MS and HPLC analyses. Its defined molecular structure enables scientists to use it as a benchmarking or derivatization reference when detecting similar enone or aromatic compounds. Handling and usage require documented purity and traceability, and all batches support compliance with international laboratory standards. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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As a chemical manufacturer, the trust placed in production processes defines the reputation we build year after year. Consistency, exactness, and transparency guide every batch. Cinnamylidene acetone has become one of our stand-out offerings—customers turn to us when precision and material quality matter most. Years on the production floor, refining our synthesis, have shown exactly where this compound can make a difference.
Customers approach us with exacting specifications. Sometimes the stakes involve downstream pharmaceutical syntheses, or new research in academic labs. Other times, clients require secure, scalable quantities for flavor, fragrance, or specialty chemical formulations. Every client wants to know they’ll receive a product meeting or exceeding published purity. With cinnamylidene acetone, we regularly deliver purities upwards of 99%. This isn’t a marketing boast—retention samples, chromatograms, and reference standards cement that claim.
We source raw materials under strict standards and transparently log every input. In synthesis, reaction conditions are closely controlled—timing, temperature, reagent ratios—since slight deviations can cloud the final product with unwanted byproducts. Even after purification, testing doesn’t stop at a single analytical check. Thin layer chromatography, GC-MS, melting point, and spectroscopic data give a full view of each lot before we ship. Stability, storage, and packaging all play their part, but if the original sample doesn’t meet our standards, it doesn’t leave our plant.
Most users seeking cinnamylidene acetone already know its formula: C12H12O, CAS number 614-62-6. It holds a special place among α,β-unsaturated ketones. The extended conjugation within its molecule results in reactivity patterns distinct from its simpler cousins, such as benzylidene acetone or acetophenone derivatives.
This molecular structure gives cinnamylidene acetone enhanced electron delocalization, affecting its UV absorbance and how it behaves in both nucleophilic and electrophilic additions. Experienced manufacturers pay close attention to subtle hints from reaction monitoring, using these as signposts to keep unwanted isomers or side products out of the final product stream. Customers can rely on its stability in ambient transport—stored in amber glass to avoid photochemistry-induced degradation—arriving ready for intended transformations or further derivatization.
Researchers and industrial customers lean on cinnamylidene acetone’s unique behavior in condensation, Michael addition, and as a building block for more elaborate molecular architectures. Pharmaceutical research groups, for instance, have explored it as a scaffold for anti-inflammatory and anti-cancer agent projects, because its structure allows modifications at multiple positions without losing the conjugated backbone. This flexibility opens doors for medicinal chemistry that aren’t possible with less-functionalized ketones.
Flavor and fragrance developers exploit the cinnamyl backbone as a launching point for nuanced aroma profiles. Its warm, spicy character blends well, but it also offers sites for further modification to shift sensory attributes as desired. The synthetic chemist’s toolkit expands with this molecule: you can introduce halogenation, reduction, oxidation, or cross-coupling without significant loss of material, provided you have a manufacturing partner who understands the importance of reagent purity and process consistency.
Clients often ask for specific physical forms or grades: crystalline solid, fine powder, or in some cases, a solution in inert solvent for rapid dosing in automated systems. Years of responding to these requests taught us the importance of nimble production. We maintain standard models for typical research and industrial use—solid form, purity above 99%, well-characterized melting point within the range of 74-78°C—but for custom processes, our batch lines can adapt.
For large-scale industrial synthesis, granulation and flow properties sometimes matter more than initial melting point. We deploy custom sieving and milling based on client feedback. Where sensitive downstream chemistry demands, we evaluate solvent residues in the part-per-million range, removing last traces of polar or non-polar solvents according to the customer’s intended application. If specifications evolve mid-project, our teams work alongside procurement and technical staff, documenting how changes will impact both supply timing and cost, always referencing prior successful batches for support.
Not every substituted acetone or enone behaves the way cinnamylidene acetone behaves in practice. Chemists accustomed to chalcones or benzylidene acetones sometimes expect similar reactivity under basic or Lewis acid conditions. Years spent testing parallel routes proved that cinnamylidene acetone’s electronic distribution makes it less prone to unwanted polymerization, and its Michael acceptor strength can outperform more basic analogs. This translates into higher yield and less side-reaction material, essential for scale-up where reaction work-up becomes expensive.
Another misconception circulates relating to storage and degradation: this compound isn’t universally fragile, but improper packaging or prolonged light exposure alters the product. More than once, customers switching from non-manufacturer sources brought us degraded, discolored material from basic storage in clear plastic. Our internal SOPs call for amber glass, moisture scavengers as needed, and documented shelf-life studies—even those not required by regional regulation. Experienced users quickly learn that saving a few cents on packaging can introduce headaches in cleaning reaction vessels or purifying downstream products.
Scaling production from bench-top to full-plant brings its logistical puzzles. Early in our experience, we saw how slight changes in the grade of base—potassium carbonate, sodium ethoxide, etc.—could introduce unexpected side-products. Years later, by tweaking reagent lots, watching water content with coulometric titration, and choosing reactor materials to avoid catalyzing decomposition, we consistently achieve tight range specifications batch after batch.
Instrumentation investment reflects this drive. Real-time spectroscopic analysis tells us where the reaction stands, so no portion of the batch lingers in a decomposition-prone intermediary stage. Some clients tour our site to audit practices, and most questions revolve around impurity profiles and trace contaminant management. We gladly open our lab books and show live data. By retaining samples from every batch, we’ve built up an extensive verification library—a clear edge for clients who must demonstrate traceability for regulatory or internal audit purposes.
Raw material shortages and pricing fluctuations test every chemical business. We’ve endured tight quarters for key starting aldehydes, and at times, supply lines for bases and solvents stretched by regulatory changes. Open communication with suppliers, not middlemen, has allowed us to forecast interruptions early, adjust batch timing, and avoid emergency substitutions that can compromise product quality. Customers appreciate this transparency when their own supply schedules face similar risk. In past years, freight delays caused by border checks or new export controls led us to keep larger on-site inventories, absorbing some costs so our clients could rely on timely deliveries without batch switching or spec compromises.
The industry’s standards have shifted: chemical manufacturers who treated worker and environmental health as afterthoughts only risked accidents, citations, and client distrust. In our plant, each batch campaign begins with up-to-date MSDS review, equipment checks, and direct communication with floor management. Exhaust systems capture airborne ketone traces, and workers wear PPE regardless of shift or experience. Waste streams undergo neutralization and active monitoring for residual organics before discharge, as neighboring communities watch industry practices with keen interest.
Clients sometimes ask for documentation on green chemistry metrics or evidence for solvent recovery rates. We invest in onsite recovery units—where possible, reusing or reclaiming process solvents both lowers cost and keeps our downstream footprint smaller. Cinnamylidene acetone’s synthesis doesn’t require heavy metals or exotic reagents, and our team continues searching for process tweaks that shrink non-recoverable waste. Contractors and visitors always receive clear orientation on safety zones and restricted areas, so audits can proceed with full confidence.
Research customers continually present us with new challenges. Electronic devices, optoelectronic materials, and functional polymers increasingly look beyond standard raw materials, and cinnamylidene acetone’s conjugated system offers noteworthy properties for these advanced applications. Its photoactive nature, for instance, allows tuning of electronic attributes through derivatization or doping, enabling possible use in OLEDs or sensor devices.
Process improvements don’t stand still. Lab-scale runs investigating alternative catalysts or greener solvents sometimes lead to full-scale change. With cross-functional teams drawing insights from both R&D and floor operations, our manufacturing adapts without sacrificing reliability. Clients developing new therapeutic scaffolds occasionally provide data that help us adjust process points for improved throughput or lower impurity levels. Knowledge flows both ways: feedback loops turn customer needs into on-site solutions, not abstract improvement plans.
The manufacturing environment is never static. Shipping, regulatory, and cost pressures ripple through the industry year-round. Relationships with clients, built on visits, calls, and problem-solving through rush orders or process hiccups, stand as our truest competitive asset. When customers face an unexpected purity requirement or need to increase shipment frequency, open dialogue shapes outcomes that benefit both parties.
Manufacturing isn’t about faceless transactions. Our plant staff remembers the first time a client called to say a shipment, delivered in poor packaging from another source, nearly derailed a research project. Since then, we’ve changed both protocol and communication, ensuring each batch meets the needs of those at the research bench or the production line. Cinnamylidene acetone’s value lies not only in its chemical properties, but in the processes, team effort, and client partnership behind every lot shipped.
More supply chains rely on multiple middlemen than ever. Only manufacturers with full visibility over every step—from reagents in the door to finished product in the crate—can provide answers when issues arise. Clients depend on direct sourcing for traceability, reliable documentation, up-to-date certificates of analysis, and a rapid response when questions come up, whether over email or a phone call.
Cinnamylidene acetone may be just one item in a vast chemical inventory, but each batch reflects years of process knowledge, infrastructure investment, and steady improvement. Customers relying on this active intermediate stake their success, in part, on our ability to learn and adapt. It’s this legacy of careful, consistent manufacturing—not just a label or a test result—that keeps clients coming back season after season.