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Rafoxanide

    • Product Name Rafoxanide
    • Alias Halox
    • Einecs 259-550-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    787001

    Name Rafoxanide
    Chemical Formula C19H11Cl2I2NO3
    Molecular Weight 661.01 g/mol
    Appearance White to off-white crystalline powder
    Solubility In Water Practically insoluble
    Melting Point 224-226°C
    Usage Anthelmintic (used to treat parasitic worm infestations in animals)
    Mechanism Of Action Uncouples oxidative phosphorylation in parasite mitochondria
    Cas Number 22662-39-1
    Route Of Administration Oral, sometimes injectable for veterinary use

    As an accredited Rafoxanide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Rafoxanide is supplied in a sealed, amber glass bottle, labeled clearly, containing 50 grams of fine, off-white crystalline powder.
    Shipping Rafoxanide is shipped in tightly sealed, labeled containers to prevent moisture and light exposure. Packaging complies with hazardous material regulations. During transit, it is kept at ambient temperature and stored away from incompatible substances. Appropriate documentation and safety data sheets accompany the shipment to ensure safe handling and regulatory compliance.
    Storage Rafoxanide should be stored in a tightly closed container, protected from light and moisture. Keep it in a cool, dry place, ideally at room temperature (15-30°C). Ensure the storage area is well-ventilated and away from incompatible substances, such as strong oxidizing agents. Keep out of reach of children, pets, and unauthorized personnel to ensure safety.
    Application of Rafoxanide

    Purity 98%: Rafoxanide with purity 98% is used in livestock parasite control, where it effectively eliminates liver flukes and reduces reinfection rates.

    Melting Point 228°C: Rafoxanide with a melting point of 228°C is used in oral suspension formulations, where it ensures stability during heat sterilization processes.

    Particle Size <5 µm: Rafoxanide with particle size less than 5 µm is used in injectable veterinary solutions, where it enhances bioavailability and rapid absorption in target animals.

    Stability Temperature 40°C: Rafoxanide stable up to 40°C is used in tropical field applications, where it maintains efficacy under elevated storage temperatures.

    Water Solubility <10 mg/L: Rafoxanide with water solubility less than 10 mg/L is used in feed additive preparations, where it allows for uniform dispersion and consistent dosing.

    Molecular Weight 514.7 g/mol: Rafoxanide with a molecular weight of 514.7 g/mol is used in anthelmintic bolus manufacturing, where it aids in accurate formulation and controlled delivery.

    Viscosity Grade 200 cps: Rafoxanide with viscosity grade 200 cps is used in oral drench formulations, where it prevents sedimentation and ensures homogeneous administration.

    Assay 99%: Rafoxanide with assay 99% is used in pharmaceutical compounding, where it guarantees high therapeutic activity and minimized impurities.

    Shelf Life 36 Months: Rafoxanide with a shelf life of 36 months is used in long-term veterinary supply chains, where it assures extended product viability and inventory flexibility.

    Bulk Density 0.42 g/cm³: Rafoxanide with a bulk density of 0.42 g/cm³ is used in large-scale feed milling, where it facilitates accurate mass flow and consistent batching.

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    Certification & Compliance
    More Introduction

    Rafoxanide: An Essential Dewormer for Livestock Health

    Understanding Rafoxanide and Its Place in Modern Animal Care

    Farmers and veterinarians often battle parasites in livestock, and rafoxanide shows up as an important ally in that fight. It seems like every year, weather changes and grazing habits make life easier for fluke, roundworms, and other pasture dangers. Rafoxanide gives those who look after sheep, cattle, and goats a tool that pairs reliability with practical effectiveness. The chemical itself belongs to the salicylanilide class and focuses its activity on liver flukes and blood-feeding nematodes—a narrower but crucial range in the world of ruminant parasites.

    Unlike some broad-spectrum dewormers that try to do it all and end up weakened by resistance, rafoxanide sticks with specific enemies. It’s a known flukicide; in my years on sheep farms and hearing from dairy producers, rafoxanide has built trust not through splashy promises but repeated proof in the field. Animals that carry chronic fluke infections often act dull and lag in body condition, costing farmers money in feed with less return. After treating with rafoxanide, folks see the difference: coats shine, weight gain improves, grazing patterns return to normal. These changes matter, not only for animal health but for a farm’s bottom line.

    How Rafoxanide Differs from Other Dewormers

    It’s easy to mix up dewormers on the market, especially with names blending together. But rafoxanide doesn’t aim to be everything for everyone. It targets mature liver flukes and haemonchus contortus, which are responsible for major production losses worldwide. Unlike levamisole or ivermectin, rafoxanide focuses on bloodsucking species and not gut worms or lungworms. This may seem like a drawback at first glance, but specialization gives it power where a farm faces recurring fluke or haemonchus outbreaks.

    I’ve talked with people who tried broad-spectrum products in areas known for heavy fluke pressure, only to stay frustrated each season. When they switched to rafoxanide, liver checks at slaughter and overall herd health often improved. The science backs this: liver fluke infection rates and egg counts drop after treatment, especially in wet, marshy grazing regions. It works through disrupting energy metabolism in the parasite, leading to its death and eventual elimination from the animal’s body.

    On the other hand, some synthetic pyrazinoisoquinoline drugs, like praziquantel, focus on tapeworms rather than liver or blood-feeding nematodes. Some benzimidazoles, like albendazole or fenbendazole, provide broader spectrum, but have lost much of their effectiveness as resistance spreads. Rafoxanide’s primary value stems from targeted reliability, not the largest menu of targets.

    Specifications and Preparations You’ll Find

    On farm supply shelves, rafoxanide typically appears as an oral drench, with the most common concentrations optimized for correct dosages by weight. Dose rates follow recommendations tied to the animal species—sheep or cows require different amounts, often quoted in mg per kg of body weight. This ensures both effective treatment and safety, avoiding toxic effects while clearing parasites.

    Some forms combine rafoxanide with other actives. For example, a compound drench might marry rafoxanide to oxyclozanide, unlocking wider fluke coverage or pairing with levamisole for broader nematode control. These blends deserve careful reading of labels and withdrawal times. Solo rafoxanide suits targeted treatment rounds, such as after rain-heavy seasons or known risk periods, while combinations help in mixed-infection risk areas.

    I’ve noticed that farms using automated drench guns favor liquid formulations—easy measuring and swift delivery to a flock or herd. The main thing is dose accuracy: rafoxanide’s potency means that underdosing can promote survival of parasites, leading to resistance, while overdosing risks unnecessary side effects. This careful balancing act underscores why farmers and animal health professionals weigh expert advice and lab results before tweaking protocols.

    Resistance and Responsible Use

    No one on the land wants to lose drugs that still work. Resistance creeps up when routines slip, when doses are missed or calculated by rough guesswork. Rafoxanide resists some of the widespread issues seen with other classes, but evidence has begun piling up that careless use allows resistance to build. Part of responsible farm management includes rotation of products and keeping treatment just to the animals that need it.

    I’ve spent time sitting with sheep producers during fluke season, running through FEC (faecal egg count) data before mapping out a deworming plan. Rafoxanide features as a tool, not a blanket. Veterinary advice recommends strategic use tied to known infection cycles. For example, treating after flooding in at-risk pastures, or after a positive fluke result in the flock, rather than giving it to every animal every month. Selective dosing, based on lab results, not only slows resistance but cuts down on unnecessary chemical exposures for stock and for the land.

    Why Rafoxanide Matters to Livestock Producers

    Efficient parasite control keeps flocks and herds productive. In areas where liver fluke remains stubbornly present, rafoxanide offers one of the few practical shields left for animals grazing snail-studded wetlands or floodplains. Losing animals to fluke is not just a hit to numbers—there are hidden costs in subpar wool, lower milk yields, and costly veterinary bills.

    From my own work, healthy animals act as a farm’s foundation. Dewormers with a track record like rafoxanide give reassurance, but only in the right hands. Long-term, system-wide success comes from linking careful diagnostics, clear record keeping, seasonal awareness, and collaboration with veterinary advice. This all-around effort, rather than leaning hard on a single solution, keeps rafoxanide working further into the future.

    Dosing and Withdrawal Considerations

    Rafoxanide comes with strict withdrawal periods for meat and milk. Failing to follow these rules doesn’t just risk regulatory trouble—it can close off market access and harm consumer confidence. Label guidance lays out minimum days between last treatment and sending stock to slaughter or milking for the commercial tank. Skipping these steps can leave residues behind. The best practice I’ve seen involves recording treatment dates in a farm notebook, checking animals off as they clear the waiting period, and never treating animals close to sale or calving dates unless there is no option.

    I’ve had conversations with producers who lost premiums or had loads of milk rejected when a single animal’s off-label treatment spoiled the tank. Rafoxanide holds value on the farm, but only if respect for these timelines stays front and center. Nothing undermines a good drug like residue scandals or breached trust in the food supply chain.

    Practical Tips for Getting Results with Rafoxanide

    A few guiding principles rise to the top: weigh animals or at least group by close weight, use calibration tubes or drench guns with regular checks, and make sure the product’s storage conditions suit your local shed or dispensary. Heat, light, and moisture all degrade drugs over time—and old, compromised medicine works less reliably.

    Animal behaviour often reveals where fluke or haemonchus lurk. Watch for lost condition, pale gums, slow weight gain, or bottlenecks in lamb crops. Pairing these observations with lab data gives clarity on the real cycle of infection. Some producers combine regular pasture rotation, snail management (removing slow-moving water and draining ditches), and strategic drenching. This kind of full-circle approach reduces fluke habitat and lowers total treatments needed.

    Comparing Cost and Value with Other Options

    Cost comes into every farm conversation. Some dewormers get priced as short-term savings, but hidden losses from resistance or incomplete parasite control pile up over time. Rafoxanide’s cost per dose sometimes runs higher than simple older chemicals, but the payback shows up in cleaner livers at processing and better-performing stock. The peace of mind in knowing that the treatment works—confirmed by lower worm egg counts—proves hard to match when profit margins are tight.

    I’ve heard the debate around cocktail approaches: combining multiple wormers to cover all bases. While there’s logic in sweeping across as many parasites as possible, the risk lies in erasing drug options for future years. Rafoxanide finds a solid spot as a mainstay in farms where fluke or haemonchus drives the main losses. Those dealing with lungworm, tapeworms, or mixed gut nematode challenges often need to pair with another targeted product, ideally one from a different class, timed so that drugs retain their punch for years ahead.

    Environmental and Food Safety Considerations

    Everything poured onto a farm—drench or spray—eventually affects soil, water, and food systems. Rafoxanide products, like many antiparasitics, break down through animal metabolism and environmental exposure, but some residues pass through into dung or wash into surrounding fields. Maintaining correct doses not only keeps animals safe but shields beneficial insects and soil health from unnecessary chemical load.

    Every farm wants a flourishing land base for the next generation. That means matching parasite management with good pasture care, waterway fencing, and waste handling. Overusing any one group of drugs—rafoxanide included—can heighten risk to local biodiversity and create “hot spots” for residue buildup. Animal health teams often recommend using faecal egg counts and fluke testing as regular monitoring tools. These efforts zero in on problem patches and trim back broad chemical use across the entire property.

    Lessons from Field Failures and Successes

    Experience counts more than any sales sheet. I’ve seen flocks lose half their lambs to fluke outbreaks when weather changes caught everyone by surprise. Year after year, doing the same treatment at the same calendar date led to disappointing results, especially when resistance set in. Those who kept best records, used data from labs, and followed independent veterinary advice outperformed their neighbors. Rafoxanide became less of a routine and more of a targeted fix. Blending ongoing pasture improvements with smart, selective drenching changed outcomes.

    Some of the toughest lessons repeat: misjudging weights causes dosing mistakes, rushing treatments while animals struggle in the yard leads to spills or missed doses, skipping label directions on withdrawal dates risks bad news at the market. Training farmhands and family helps, but having a farm culture around careful management makes a true difference. No medicine, no matter how strong, will outlast misuse or overuse.

    What Makes Rafoxanide Trustworthy

    Reputation doesn’t build overnight. Rafoxanide works as a cornerstone in regions battling heavy liver fluke loads and for those needing fast action against haemonchus. Its trusted standing comes not only from clinical studies but from straightforward results seen each season in flocks and herds. Veterinarians point to decades of safe, predictable use when label directions are followed.

    Reliable medicines, in my experience, show their value year after year, without drama or surprise. They reward the careful, not the reckless. They slot into integrated programs built on observation, recording, and learning from each season’s patterns. Rafoxanide delivers for those who pay attention, balance science with hands-on know-how, and never forget the animal at the centre of the story.

    Supporting Livestock Health into the Future

    Veterinary science moves forward, but parasite challenges only shift, never really going away. Rafoxanide holds its ground by keeping focus tight and effectiveness high. It does one thing well and, used wisely, remains dependable. The biggest gains I’ve seen in animal health come not from gadgets, but matched programs that adapt year-to-year and balance medicine with management.

    For those facing parasite hot spots or rebuilding herds after tough years, rafoxanide can tip the scales back toward health. The decision to reach for a bottle of this dewormer should always start with facts—faecal egg counts, local infection patterns, and current resistance data. It’s not a shortcut, but a proven step on the path to sustainable farming.

    Encouraging Thoughtful Use and Future Solutions

    Looking ahead, the farming community faces a shared task: keep medicines like rafoxanide viable for as long as possible. The path forward lies in careful diagnostics, honest record-keeping, smart pasture management, and a willingness to follow the science, not rumor or tradition. Watching drug effectiveness and resistance trends, sharing information with neighbors, and connecting with veterinary professionals keeps knowledge up to date and approaches flexible.

    Some countries invest in resistance monitoring networks and on-farm advisory services, helping turn the tide before major setbacks. I’ve read stories from regions where coordinated testing and farmer networks have brought parasite pressure down without explosive increases in chemical use. Those examples point to the future: not more of the same, but better-targeted approaches, with rafoxanide playing a focused part.

    Final Reflections: Tools, Trust, and Farm Success

    Animal health never stops moving. Rafoxanide proves itself year after year in tough environments, giving livestock producers a reliable tool. But long-term greatness comes from more than any bottle or brand—it’s shaped by how we use what we’ve got. Judging each season’s needs, keeping records, swapping notes with other farmers, and working with vets pays bigger dividends than chasing the latest wonder product.

    In my years around paddocks and processing sheds, the farms that blend old-school attention to detail with current science always rise above. Rafoxanide fits that mold: time-tested, effective, and safe when used in context. Those who respect the lessons learned—good dosing, choosing the right moment, and pairing parasite control with broader health plans—will keep their animals productive, their land healthy, and their place at the table secure.