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HS Code |
994067 |
| Common Name | Prothioconazole |
| Chemical Formula | C14H15Cl2N3OS |
| Cas Number | 178928-70-6 |
| Iupac Name | 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione |
| Molecular Weight | 378.26 g/mol |
| Appearance | White to off-white crystalline solid |
| Solubility In Water | 8.6 mg/L at 20°C |
| Melting Point | 87-89°C |
| Mode Of Action | Demethylation inhibitor (DMI), inhibits fungal sterol biosynthesis |
| Usage | Systemic fungicide for cereals, soybeans, and other crops |
| Toxicity To Humans | Low acute toxicity |
| Environmental Persistence | Moderately persistent in soil |
| Logp | 3.7 |
As an accredited Prothioconazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The Prothioconazole packaging is a sturdy 1-liter white HDPE bottle, featuring hazard symbols, a green label, and clear usage instructions. |
| Shipping | Prothioconazole is shipped in tightly sealed, labeled containers, compliant with chemical safety regulations. It is classified as a hazardous material, requiring transport by licensed carriers with proper documentation. Packages are protected from moisture and incompatible substances, and storage is in cool, well-ventilated areas. Personal protective equipment is recommended for handling. |
| Storage | Prothioconazole should be stored in its original, tightly closed container in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances such as oxidizing agents. Keep it out of reach of children, pets, and unauthorized persons. Avoid temperature extremes and protect from moisture to maintain stability. Store according to local regulations for agricultural chemicals. |
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Purity 97%: Prothioconazole 97% purity is used in wheat disease management, where it ensures effective suppression of Fusarium head blight and enhanced yield protection. Stability temperature 50°C: Prothioconazole with a stability temperature of 50°C is used in high-temperature storage conditions, where it maintains consistent fungicidal activity over extended periods. Molecular weight 359.4 g/mol: Prothioconazole with a molecular weight of 359.4 g/mol is used in broad-acre cereal crop treatments, where optimal molecular attributes contribute to rapid systemic translocation and efficient disease coverage. Particle size D90 < 5 µm: Prothioconazole with D90 particle size below 5 µm is used in foliar spray formulations, where fine dispersion enhances leaf surface adherence and uniform protective coverage. Viscosity grade low: Prothioconazole with low viscosity grade is used in tank-mix applications, where superior suspension properties enable compatibility with diverse agrochemicals and minimize nozzle clogging. Formulation EC 250 g/L: Prothioconazole EC 250 g/L is used in fungicide spraying on barley fields, where concentrated active ingredient delivers fast-acting and long-lasting control of leaf spot diseases. Melting point 117°C: Prothioconazole with 117°C melting point is used in granule production, where thermal stability ensures integrity during high-temperature processing and storage. Solubility in water 70 mg/L: Prothioconazole with water solubility of 70 mg/L is used in irrigation-based delivery systems, where controlled solubilization prevents run-off and optimizes plant uptake. Residual activity 21 days: Prothioconazole with 21-day residual activity is used in preventative crop treatment programs, where prolonged efficacy reduces the frequency of fungicide applications. pH stability range 4-8: Prothioconazole with pH stability from 4 to 8 is used in various soil types, where chemical resilience guarantees reliable performance across diverse environmental conditions. |
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Farmers constantly battle fungal diseases that threaten yield and quality. I’ve spent time in fields where the signs of infection can show up overnight, with leaf spots and blight moving quickly. In those moments, the right fungicide makes the difference between a salvageable harvest and real loss. Prothioconazole stands out because it delivers what growers expect—timely protection that keeps crops standing strong.
Prothioconazole belongs to the triazole class of fungicides. It’s crafted as a broad-spectrum systemic product, hitting a range of fungal pathogens that often sneak in without warning. Its chemical backbone—known technically as a DMI (demethylation inhibitor)—goes to work by targeting the biosynthesis of ergosterol, a vital component in fungal cell walls. That makes it tough for diseases like Septoria, Fusarium, and rusts to gain a foothold in cereals.
Many growers look for something that moves quickly into leaves and stems, but also stays put for weeks. Prothioconazole travels into plant tissue swiftly and remains there, forming a shield during vulnerable stages like flowering and grain filling. This matters—a fungicide’s value isn’t only in killing fungi on contact, but in lasting through wet spells and high-risk periods, especially in regions where the weather turns on a dime.
You’ll find Prothioconazole in suspension concentrates or emulsifiable concentrates. Choosing the right format becomes a matter of matching local water conditions and tank mixes. I haven’t met a grower yet who enjoys re-cleaning clogged nozzles, so product formulation plays a bigger role than people often think. Most modern products mix well with common adjuvants and don’t settle on the bottom of the tank, cutting down on headaches during long spraying days.
Timing is everything with fungicides. Prothioconazole enters the picture from stem elongation onward in cereals, or at key points in other crops like oilseed rape. The goal isn’t blanket spraying, but well-timed applications that match disease risk. I’ve watched experienced applicators check leaves for the first sign of infection—then pull out Prothioconazole to stop spread before it jumps across rows. Its kickback activity lets farmers catch early signs of infection, not just prevent them.
In years with high disease pressure and tight margins, rotating modes of action helps keep resistance at bay. I’ve seen Prothioconazole used in alternation or tank mixes with strobilurins, SDHIs, and older chemistry. That’s not just about following best practice—it directly translates to longer-lasting disease control and fewer surprises come harvest. Growers in wetter climates, in particular, value a fungicide that can handle prolonged leaf wetness without washing off or fading out.
Dose varies by crop and pressure. Many cereal growers use rates around 100 to 150 grams of active ingredient per hectare, adjusted based on flag leaf emergence, infection levels, and weather patterns. Careful record keeping matters; resistance management only works with clear histories of product mixes and timings. Most extension agents recommend no more than two DMI applications per season, which keeps Prothioconazole in the rotation for years, not just seasons.
Many triazole fungicides crowd the market. Over time, I’ve seen names like tebuconazole, propiconazole, and epoxiconazole move through recommendations. What sets Prothioconazole apart is its reliable control of tough fungal groups—particularly Fusarium and Septoria. Those two can break weaker fungicides, and in some regions, resistant strains appear where older triazoles have slipped.
Unlike some other DMIs, Prothioconazole doesn’t just linger on the leaf surface. It moves in, spreads throughout tissue, and keeps working as fungi try new ways to survive. Researchers note its unique structure helps it dodge some resistance pathways, which extends its usefulness as resistance to older triazoles builds up. I’ve seen plots where generic triazoles wilt under Fusarium onslaught, but Prothioconazole keeps heads clean and grains full.
Some fungicides pack a higher risk of crop stress, yellowing, or growth suppression. Direct comparison trials show Prothioconazole plays more gently with emerging plants, making it easier to use during sensitive stages—especially in high-stress conditions or on lighter soils. In practical terms, that means growers don’t have to trade improved disease control for lower yields or plant setbacks.
Tank mix flexibility also boosts Prothioconazole’s appeal. While no product mixes with everything, this one fits cooperatively with many herbicides and micronutrients. The result: fewer sprayer passes, less soil compaction, and more time spent looking ahead instead of playing catch-up with every new threat.
Years of walking farm fields have taught me that local experience beats textbook knowledge. In wet years, wheat growers talk about Fusarium and mycotoxin risk almost every day. I’ve watched trials where Prothioconazole pulled down DON (deoxynivalenol) levels in harvested grain, enough to tip the scale from rejected to accepted loads. That single advantage has saved farm incomes and contracts for more than a few operations.
Growers raising malting barley or seed wheat wrestle with constraints on what they can spray. Prothioconazole’s residue profile matches up with most market requirements, which means there’s less anxiety about keeping contracts or hitting export tolerances. It’s worth pointing out that residue studies—looked at by regulators before approval—measure not only safety for the end consumer, but also how fast and reliably the product breaks down in crop and soil.
Comparing seasons side by side, yield bumps often follow smart fungicide programs. In large plot demonstrations, Prothioconazole-based treatments regularly edge out older products, often by enough bushels to pay for the extra investment. That’s not every year, of course—disease pressure drives value. But seeing the clear heads and clean leaves that follow a timely application makes a lasting impact.
One season, fields I scouted saw early yellow rust and Septoria pressure, but the farmer holding off until just before flag leaf stage with Prothioconazole locked in control through the final weeks. Later rain would’ve broken through under lighter protection, but in that case, a single right-timed shot covered the whole field until harvest. Newer fungicides often promise that kind of result; in this case, real-world use matched those claims.
Food buyers, consumers, and regulators care increasingly about sustainable agriculture. Fungicide use always attracts scrutiny, especially when it comes to rotations and impact on beneficial organisms. Prothioconazole fits comfortably in integrated pest management programs. Its action window gives room to scout, evaluate, and intervene only when needed—not by calendar, but by risk.
Europe’s farm policies and sustainability schemes look closely at every input. Triazole use can spark debate, but research around Prothioconazole’s soil breakdown and low toxicity to pollinators stands out. Independent review panels in the EU and Australia weighed its soil and water mobility, uptake in non-target species, and effect on beneficial insects, and found manageable risks when used according to guidelines.
I’ve spoken to organic and low-input producers who note that reducing disease pressure with clean rotations and resistant varieties forms the foundation of their approach. For conventional growers, Prothioconazole steps in as a tool—used sparingly, chosen wisely, and rotated intelligently. Overuse or poor stewardship can bring resistance faster, so extension agencies encourage mixing and alternating with other fungicide groups.
Farmers I work with often ask about the longer-term impact of active ingredients on soil structure and microorganism balance. Studies from research institutes show that Prothioconazole, when applied at recommended rates and intervals, leaves underground communities intact. Soil fauna—earthworms and microarthropods—persist and thrive. That assurance encourages growers in regions where soil biology underpins whole-farm productivity.
The most respected agronomists I know talk about resistance in plain terms—once a fungicide loses its edge, bringing it back isn’t easy. With Prothioconazole, careful customers rotate with non-DMI chemistries whenever possible. Results from multi-year trials reinforce this: resistance management not only extends the tool’s life, but also boosts returns over time.
Some regions saw early resistance to older triazole options like tebuconazole. Prothioconazole, by design, offers a longer residual window and somewhat different binding sites in fungal enzymes. These distinctions buy time. Where strobilurins lost ground to resistant strains, Prothioconazole carried those programs through until new SDHI actives joined the fray.
Good practice relies on more than chemistry. Variety selection, careful timing, and keeping detailed records anchor successful disease control. Those who treat Prothioconazole as one part of a bigger strategy—rather than a silver bullet—see better long-term outcomes. This kind of cautious optimism sets sustainable farms apart, especially in complex environments with shifting disease threats.
People care deeply about safety, both their own and for those around them. Regulatory review of Prothioconazole spans not only residue in food but also operator exposure and bystander safety. Product labels include clear instructions—personal protective equipment recommendations, restricted entry intervals, and environmental safeguards. I’ve attended training sessions with operators who take these guidelines seriously, knowing that missteps harm themselves or neighbors.
From a practical standpoint, the product’s low vapor pressure and stable formulation mean fewer headaches related to drift and off-target movement. Sprayers operate early in the morning or late in the evening when wind drops, further reducing risk. It’s no secret that regulatory approval gets renewed or withdrawn based on real-world incident reports. So far, the track record with Prothioconazole remains favorable in the places I’ve followed.
Farm advisors and co-ops who source Prothioconazole reinforce the importance of proper storage and transport. Keeping it out of direct sunlight and extreme cold helps maintain shelf life and reactivity. In several cases, growers share facilities, so careful labeling and segregation from food products prevent accidental cross-use.
Modern farming faces increasing demands from all sides. A growing public expects food free of contamination, environmental regulators track chemical footprints, and international buyers lose interest in crops showing exceeded residue limits. Prothioconazole doesn’t operate in a vacuum. Its fate in soil and water—and persistence or movement outside the application zone—matters up and down the value chain.
Monitoring from universities and independent labs regularly reports residue levels in runoff, groundwater, and non-target vegetation. Results published over the last decade show low rates of movement outside field boundaries with current use patterns. Where catchment studies report trace finds, guidance adjusts—reducing rates or increasing buffer zones along sensitive waterways.
Biodiversity and pollinator safety form another key piece of the puzzle. I’ve spent time on farms that border field margins, hedgerows, and bee habitats. Local monitoring over multiple years finds pollinators unaffected when spray windows close before flowering, and when label rates hold firm. The bigger environmental risks in real life often come from mistakes or miscalculations, not from the product itself.
As more countries tighten both label requirements and monitoring, proactive compliance protects market access. Detailed record-keeping, consistent calibration of equipment, and regular reviews of best practice keep responsible users in line with evolving regulations. Groups who slip risk the entire sector’s license to operate—a risk few are willing to take.
Input costs shape agronomic decisions as much as pest and weather risks. Prothioconazole usually lands in the mid- to upper-priced tier of fungicides. Some farmers hesitate before paying extra per hectare. The up-front premium does pay off under pressure: in years with heavy disease outbreaks, preventing a single lost ton per hectare offsets the difference, especially when grain markets run strong.
Farmers with fewer acres spread cost out less, so value calculations vary. That said, even in tight market cycles, extension trials comparing untreated, standard triazole, and Prothioconazole-treated plots regularly demonstrate yield and quality benefits. These aren’t just numbers on a spreadsheet—the difference lands as more clean, saleable grain at harvest.
The economics of resistance management also enter the equation. Skipping effective fungicides can mean running into disease outbreaks that older products can’t handle. A lost crop to Fusarium or Septoria leaves marks for years, especially with rising seed and input costs. The long game—planning for durability of action and broad spectrum coverage—shifts attention toward tried-and-tested solutions like Prothioconazole.
Access to solid information and on-the-ground support creates successful outcomes. Manufacturers and distributors invest in field days, product workshops, and demo plots. I’ve watched these sessions turn skeptics into converts by showing what works, and why. Learning directly from local trials cuts through hype—no substitute for seeing results under real stress, on local soils, with familiar equipment.
Extension agents pick up feedback from users, bring it back to researchers, and tweak programs over time. In some regions, farmer groups or co-ops pool knowledge after tough seasons to compare approaches. Reports often end up as new recommendations for mixing partners, spray intervals, and integrated management tactics.
Technology also plays a role. As digital farm management improves, users track application dates, rates, and weather in real time. Decision support systems built off local datasets now recommend Prothioconazole only in fields where weather and historical disease signals match. That smarter targeting saves the product for cases where it counts most.
No product answers every question in crop disease management. Pathogen evolution, new farming practices, and changing climate all shift the goalposts. Prothioconazole earns loyalty by offering flexible, sustained control even as old solutions drop away. Its place in the toolbox makes sense for growers chasing both high yields and resilient, market-ready harvests.
Farmers watch emerging disease trends—new rust races, shifting Fusarium species, novel leaf spots—and share results openly. This feedback cycle guides not just chemistry choices, but seed selection, planting date decisions, and field layout. Years with late wet periods or surprise heat spikes make having a broad-spectrum, systemic product on hand vital.
Across different regions, adaptability underpins success. Some hot, dry seasons trigger early harvests, requiring earlier spray timing. Wet springs push risks later, calling for longer protection. With Prothioconazole, I’ve seen success in everything from rolling prairie to small valley bottoms. Its design keeps it in the mix amid shifting realities.
In my experience, farmers and agronomists who openly review the limitations and strengths of each fungicide make fewer costly mistakes. Prothioconazole offers a reliable combination of broad control, gentle crop interaction, and resistance protection, all supported by a growing library of independent field studies. New threats and regulations will demand even more flexibility, but for now, this product covers the key bases for sustainable, robust cereal and oilseed protection. The future holds more change, but knowing what works today brings needed confidence.