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HS Code |
154174 |
| Chemical Name | P-Cresol |
| Iupac Name | 4-methylphenol |
| Cas Number | 106-44-5 |
| Molecular Formula | C7H8O |
| Molar Mass | 108.14 g/mol |
| Appearance | colorless to pale yellow solid |
| Melting Point | 35 °C |
| Boiling Point | 201 °C |
| Density | 1.034 g/cm³ |
| Solubility In Water | 2.4 g/100 mL (20 °C) |
| Flash Point | 86 °C |
| Odor | phenolic, tar-like |
| Pka | 10.26 |
As an accredited P-Cresol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | P-Cresol is packaged in a 500 mL amber glass bottle with a secure cap, featuring hazard labels and clear identification markings. |
| Shipping | P-Cresol should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled as hazardous. Transport must comply with relevant regulations (e.g., DOT, IATA) due to its flammable and toxic nature. Ensure containers are protected from physical damage and stored upright, away from incompatible substances, in a cool, ventilated area during shipping. |
| Storage | P-Cresol should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible substances such as strong oxidizing agents. Keep the container tightly closed and properly labeled. Use corrosion-resistant containers and avoid prolonged exposure to air. Store away from food, drink, and animal feed, and ensure restricted access to authorized personnel only. |
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Purity 99%: P-Cresol with 99% purity is used in antioxidant synthesis, where high purity ensures consistent free radical inhibition. Melting Point 35°C: P-Cresol with a melting point of 35°C is used in phenolic resin production, where controlled melting ensures uniform polymer matrices. Molecular Weight 108.14 g/mol: P-Cresol with a molecular weight of 108.14 g/mol is used in agrochemical formulation, where precise weight enables accurate dosing in pesticide applications. Stability Temperature 110°C: P-Cresol with a stability temperature of 110°C is used in disinfectant manufacturing, where thermal stability guarantees efficacy during high-temperature processing. Refractive Index 1.539: P-Cresol with a refractive index of 1.539 is used in dye intermediate synthesis, where optical clarity facilitates effective chromophore development. Water Content <0.1%: P-Cresol with a water content less than 0.1% is employed in pharmaceutical intermediates, where low moisture prevents hydrolytic degradation. Volatility Moderate: P-Cresol with moderate volatility is used in flavor and fragrance synthesis, where controlled evaporation maintains aroma stability. Viscosity 1.1 mPa·s: P-Cresol with a viscosity of 1.1 mPa·s is used in lubricant additive production, where optimal viscosity ensures proper blending and flow properties. Particle Size <50 µm: P-Cresol with a particle size under 50 µm is used in catalyst manufacturing, where fine size increases surface area and catalytic efficiency. Ash Content <0.01%: P-Cresol with ash content below 0.01% is utilized in electronic chemical synthesis, where low inorganic residue maintains circuit integrity. |
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P-Cresol, also called 4-methylphenol, plays a surprising role in daily life, even though most people never hear about it. This clear to yellowish liquid finds its way into products from disinfectants to pharmaceuticals. It stands out for its balance of chemical reliability, effectiveness, and versatility. The chemical formula—C7H8O—captures a stable aromatic ring with a methyl group and a hydroxyl group. The most common form, the 99% pure model, continues to anchor standard batches for laboratory and industrial uses. This high-purity standard offers a reliable baseline for chemical reactions, quality control, and downstream manufacturing. The substance demonstrates a melting point around 35°C and a boiling point just above 200°C, placing it well within handling ranges across most industries. Reliability reaches deeper than simple numbers: the consistent purity matters more in a production setting than glossy brochures do.
Each time the chemical industry tries to solve practical problems—creating detergents, synthesizing medicines, protecting materials—engineers often turn to P-Cresol. This compound acts as a critical intermediate in producing antioxidants, polymer stabilizers, and various agricultural chemicals. Walk into a warehouse filled with plastic production lines; workers add precisely measured P-Cresol to help make butylated hydroxytoluene, known simply as BHT. BHT preserves the shelf life of everything from cosmetics to engine oils. In the pharmaceutical world, P-Cresol contributes to antiseptics and certain pain medications. Its germ-fighting power comes from disrupting microbial cell walls, a principle proved over decades of use in the field.
Concrete usage examples mean more than chemistry textbooks. During flu season, hospitals and clinics depend on disinfectant solutions, many of which list P-Cresol among active ingredients. Its scent—sharp and slightly medicinal—almost always signals a product built to kill germs. Whether in veterinary clinics or food-processing plants, professionals trust it to sanitize surfaces efficiently. Many of the same chemical characteristics that make P-Cresol valuable in the lab carry over to these real-world settings. Heat tolerance, stability, and well-studied reaction pathways let companies minimize surprises and avoid costly shutdowns.
Scientists and engineers care about exact numbers and measurable qualities. Typical technical specifications reflect priorities shaped by years of hands-on work. Pure P-Cresol usually clocks in above 99% purity. The density settles near 1.034 g/cm³ at room temperature, sure enough for tanks and dosing pumps designed for consistent flow. The low melting point means storage containers rarely freeze up—even in colder climates. In terms of solubility, P-Cresol dissolves well in alcohol, ether, and many organic solvents. Water solubility stays lower, usually under 2%, but just right for certain extraction and formulation techniques. These figures do not live in isolation. A small error in concentration or an unexpected impurity can change a batch’s performance or trigger costly waste.
Producers rarely overlook details. They confirm aspects like acidity (pKa near 10) since it influences compatibility with other chemicals. Flash point lands near 82°C, requiring proper storage to prevent accidents in fast-paced environments. Chemists working on resins or dyestuffs often track these numbers by habit, knowing an unexpected change means trouble. Every delivery batch gets tested in-house—part tradition, part insurance. In this world, consistency wins trust faster than advertising can.
Anyone familiar with chemical cousins knows that not all cresols behave the same. While o-cresol, m-cresol, and p-cresol all share a core structure, small shifts in molecular arrangement dramatically influence their uses and handling. P-Cresol brings a milder odor and more manageable toxicity compared to its counterparts, which helps workers keep it in circulation when large volumes are involved. Its relatively low volatility reduces inhalation risks, which fits comfortably with modern safety regulations and public health expectations. Lab managers—always attentive to changing air quality standards—often appreciate the difference when working on large projects.
Other common phenolic compounds, such as phenol itself, offer a stronger germicidal punch but ramp up toxicity at workplace concentrations. P-Cresol strikes a better balance. This makes it popular when the goal blends effectiveness with reasonable worker safety, especially in disinfecting closed spaces or producing consumer-facing goods. Discussions around phenols often circle back to price, supply security, and adaptability. P-Cresol consistently checks these boxes because its manufacturing process has matured for decades. The raw materials, usually extracted from coal tar or petroleum refining, remain plentiful enough to avoid crisis shortages. The market rarely sees wild swings unless outside factors disrupt the entire chemical supply chain.
I remember a summer spent in a modest adhesives manufacturing plant. During my chemical engineering internship, the boss talked way more about consistent raw material supply than the fancy technicalities that dominate textbooks. Over weeks of shadowing line supervisors, I saw firsthand how even a slight change in a precursor chemical could slow everything down. If a tank arrived with “off” cresol—just a fraction too much impurity—the quality assurance team red-tagged the whole batch. The knock-on effects rippled from the warehouse to the shipping dock. P-Cresol’s strong showing? It repeatedly tested to spec and arrived as expected, avoiding these headaches. The takeaway from days spent scraping uncured glue off machinery: reliability saves time and keeps costs predictable.
Practically speaking, control over impurities counts as much as the source itself. Raw P-Cresol, drawn from coal tar or cracked from petroleum, moves through several distillation and purification steps. Each company puts a different spin on it, but consistent attention to detail delivers a recognizable product. Industrial buyers come to know which suppliers focus on tighter tolerances and which offer bulk pricing for less demanding projects. Chemists on the production floor know a reliable number on a test sheet means smoother operations all around.
Institutions handling P-Cresol on a daily basis must pay attention to hands-on realities. The compound still counts as hazardous if inhaled or absorbed in large doses, so protective gloves and fume hoods remain standard. I recall the first time I helped unload a drum shipment; the acrid smell made me realize why suppliers insist on proper ventilation. Well-run companies train staff from day one on spill management and first aid, underscoring the need for real-world education over dry procedure manuals.
Yet, careful handling matches with smart investments in safety. With P-Cresol’s flash point higher than many flammable solvents, properly installed fire suppression and closed transfer systems tip the scale in favor of safer operations. Simple process changes—like automating liquid transfer or adding basic air monitors—reduce health risks. Clean workspaces help cut down the odds of accidental contamination, a lesson pounded in by generations of plant engineers. Over the years, steady progress in bulk handling techniques has minimized waste and moved many chemical plants closer to low-emission standards.
P-Cresol’s journey from raw material to finished product weaves through a global landscape. Most production clusters in East Asia, followed by established plants in Europe and North America. Prices track the swing of energy markets, since petroleum feedstock prices trickle down to chemical compounds all over the world. Resilient supply chains matter here, whether in response to natural disasters, transport strikes, or regulatory shifts. When supply squeezes occur, smaller regional suppliers step up to fill the gap, but industrial buyers keep close tabs on quality, not just price per ton.
Efforts to “green” the chemical industry by moving away from coal tar extraction have sparked new experiments in bio-based aromatic chemical synthesis. Pilot projects in academia and industry try to reinvent the old model: plant-based feedstocks, cleaner catalysts, lower energy inputs. The goal traces back to environmental commitments—reducing greenhouse gas emissions while keeping supply reliable. Some labs have found success fermenting biomass into cresol analogues, but large-scale commercial viability still faces hurdles. Cost, consistency, and regulatory approval always come to the fore. For now, traditional routes dominate, but innovation may soon rewrite old assumptions.
Its reach stretches far beyond industrial chemistry. Everyday necessities—cleaners, adhesives, dyes, and more—rely on predictable intermediates like P-Cresol. The world leans on countless small, reliable players within chemical supply chains: truck drivers, warehouse staff, process engineers. Their expertise keeps shipments moving and production lines open. In my own experience tagging along with delivery drivers, I noticed not only the scrutiny paid to paperwork and seals, but also the way they checked site-specific instructions. Each step, from pickup to off-loading, follows protocols focused on health and safety. Real-world implementation builds the foundation for confidence in the final product.
Take the rubber industry as another example. Chemical vulcanizers require tight quality controls, or the end product falls short in durability and resilience. Manufacturers add P-Cresol derivatives to ensure stability under harsh conditions, such as tire manufacturing. Antioxidants derived from it slow the natural degradation of materials exposed to sun and air, keeping products useful longer and cutting replacement costs. These real impacts matter to both consumers and equipment operators who depend on consistent performance under pressure.
Over time, people working with P-Cresol—scientists, engineers, technicians—refine their skills in both process improvement and troubleshooting. I learned more about chemical process safety watching senior staff spot small leaks and react quickly to unusual smells than from classroom lectures. Their instincts, built from years in the plant, fill in the gaps between theory and practice. That said, E-E-A-T (Expertise, Experience, Authoritativeness, and Trustworthiness) means more than certifications and academic accolades. It comes alive through seasoned judgment, tested SOPs, and a culture where speaking up prevents near-misses. Operators learn to spot subtle changes in odor or color, then cross-check against test results. In modern labs, digital tools track inventory, record temperature logs, and assist in compliance reporting, but someone with hands-on knowledge ties it all together.
For end-users in demanding industries, trust grows out of repeated performance. Feedback loops stretching from warehouse workers to product managers help spot trends or resolve bottlenecks. If a batch of P-Cresol underperforms or triggers a fouling issue, the news circulates fast. Team meetings revisit root causes, often confirming what experienced staff already suspect. Stories like these show how a seemingly ordinary chemical connects people, processes, and products around the globe.
Growing expectations for sustainability place new demands on chemical makers. Environmental groups urge tighter controls on emissions and push for greener inputs. In response, forward-looking firms pursue cleaner production routes and recyclable containers. Efforts to close the loop—recovering solvents and reusing purification side-streams—reduce waste and lower operating costs. At industry conferences, I have seen real excitement around digital batch tracking and smart sensors, which let teams catch impurities faster or cut down on mistakes in packaging. Yet, old-fashioned communication—staff briefings, transparent safety records, accountability meetings—still carry weight.
Not every proposed change lands smoothly. Some innovative purification steps add cost but produce only modest environmental improvement. Regulatory shifts, especially for products that end up in food or medicines, remain slow and subject to lengthy scientific review. But experience shows that modest, well-executed tweaks in equipment or process standards often bring more concrete progress. Teams that listen to the practical insights of frontline operators while incorporating new technologies usually see the best results. These lessons ring true whether working with P-Cresol or any other cornerstone chemical in the global economy.
Supply disruptions often hit small manufacturers the hardest. In the past, weather events or transport slowdowns have led to backlogs and missed deadlines. Some industrial buyers responded by diversifying their pool of P-Cresol suppliers, keeping relationships active in various regions. Others set aside more storage space or invested in tank monitoring systems. In my own tours of mid-sized chemical sites, I noticed the difference in attitude between those who plan ahead for shortages and those who scramble to catch up. A little foresight—a couple more certified vendors, improved inventory visibility—translates to fewer headaches and calmer day-to-day operations. Even slight time savings pay off, especially for products that must move quickly from storage into sensitive production lines.
Collaboration between purchasers and vendors grows more valuable each year as expectations for reliability and transparency increase. The best suppliers keep clear records, respond to concerns quickly, and encourage open feedback. This partnership mindset helps everyone weather swings in shipping schedules or fluctuating input costs. Engineers find it easier to implement small process changes or test new substitutes when the conversation flows both ways. Over time, trust amplifies efficiency and makes innovation easier to accept across the supply chain.
P-Cresol exemplifies the intersection of tradition, reliability, and smart adaptation. Its proven track record across major industries, combined with opportunities for innovation, ensures its continued relevance in a rapidly changing world. For those of us who have worked with or relied on P-Cresol—from warehouses to research labs to manufacturing floors—it stands not just as a product specification, but as a practical solution that connects expertise, experience, and the needs of modern society.