|
HS Code |
714642 |
| Name | Oxyclozanide |
| Chemical Formula | C13H6Cl5NO3 |
| Molecular Weight | 415.4 g/mol |
| Appearance | Pale yellow to yellowish brown powder |
| Solubility | Insoluble in water; soluble in ethanol and chloroform |
| Use | Anthelmintic (used to treat liver fluke infestations in animals) |
| Melting Point | 212-215 °C |
| Cas Number | 2277-92-1 |
| Storage Conditions | Store in a cool, dry place, protected from light |
| Route Of Administration | Oral |
| Target Species | Cattle, sheep, goats |
| Mechanism Of Action | Disrupts the energy metabolism of liver flukes |
| Atcvet Code | P52AG06 |
As an accredited Oxyclozanide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Oxyclozanide is packaged in a sealed white HDPE bottle, labeled, with 500g net weight and safety instructions clearly printed. |
| Shipping | Oxyclozanide is shipped in tightly sealed, labeled containers, typically as a solid powder. During transport, it is protected from moisture, heat, and direct sunlight. Appropriate hazard labeling is applied, and it complies with local and international chemical transportation regulations to ensure safety and integrity throughout shipping. |
| Storage | Oxyclozanide should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from moisture, direct sunlight, and incompatible substances such as strong oxidizers. It should be kept out of reach of children and animals. Proper labeling and secure storage help ensure safety and maintain the chemical’s stability and effectiveness. |
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Purity 98%: Oxyclozanide with 98% purity is used in commercial livestock deworming programs, where high purity ensures effective fluke elimination and reduced dosing frequency. Melting Point 180°C: Oxyclozanide with a melting point of 180°C is used in veterinary tablet manufacturing, where stable solid formulation enables consistent dosing. Particle Size <50 microns: Oxyclozanide with particle size below 50 microns is used in oral suspensions for ruminants, where fine particles promote rapid dissolution and enhanced bioavailability. Stability at 40°C: Oxyclozanide stable at 40°C is used in tropical veterinary healthcare products, where reliable potency is maintained under high-temperature storage conditions. Moisture Content <0.5%: Oxyclozanide with less than 0.5% moisture content is used in powdered premixes for animal feeds, where low moisture prevents clumping and degradation. UV absorbance 340 nm: Oxyclozanide with UV absorbance at 340 nm is used in quality control of pharmaceutical preparations, where precise detection enables accurate content verification. Solubility in ethanol: Oxyclozanide soluble in ethanol is used in injectable formulations, where high solubility facilitates preparation of clear, stable solutions. |
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Oxyclozanide attracts attention for its consistent performance in controlling certain parasitic infections in livestock, particularly trematodes like liver flukes. Many seasoned farmers know how much trouble Fasciola hepatica can cause; it drains energy from herds and impacts milk production in cattle. Oxyclozanide offers a straightforward approach to these issues, working as a fasciolicide trusted for generations. With growing concerns about animal welfare and sustainable farming practices, products that offer reliable results while fitting into daily routines deserve careful consideration.
The product usually appears as a fine, off-white powder, making it easy to mix into feed or formulate into oral drench preparations. Oxyclozanide comes in technical grade with a purity standard typically above 98 percent, meeting the requirements many veterinarians and producers look for. Its molecular structure—C13H6Cl5NO3—gives it a particular mode of action, helping it target flukes directly where they do their damage. The compound remains stable under ordinary conditions, so it stores well on farms, even in varying climates.
Keeping livestock in good health demands regular attention to parasites, particularly in regions where animals graze on moist pastures. Fluke infestations reduce weight gain and depress milk yields, hitting both beef and dairy farms. From experience, seeing the impact of chronic fluke infection—a cow eating but losing weight, a sheep's fleece dull and dry—is a stark reminder that preventive treatment pays for itself again and again. Oxyclozanide stands out for targeting adult flukes in the bile ducts. Unlike some alternatives, it does not focus on immature stages, so timing treatments to target mature parasites makes a noticeable difference in effectiveness.
Most dosing programs build around seasonality and risk factors, such as field drainage and herd movement. Once fluke counts reach a certain threshold in the herd, Oxyclozanide comes into play as an oral suspension. Farmers measure out the required dose by animal weight, deliver the product directly into the animal’s mouth, and monitor for clinical improvement. Reports describe fewer instances of bottle jaw and improved condition scores within weeks. Used as directed, Oxyclozanide shows low toxicity when compared with broader-spectrum alternatives, so it fits neatly into routine rotation programs without raising too many concerns about residues, provided withdrawal periods for meat and milk are followed.
Some products on the market promise to eliminate a broader spectrum of parasites or boast newer chemical structures. Triclabendazole, for instance, covers both immature and adult liver flukes, making it popular where juvenile flukes cause major problems. Yet concerns grow over resistance to such products, especially in areas of intensive use. Oxyclozanide, by focusing on mature flukes, keeps its place as a rotation choice to prolong usefulness of different drug classes. Nitroxynil, another comparably used drug, is usually given by injection rather than orally, and it handles a similar range of parasites. Some farmers prefer Oxyclozanide for its oral delivery, seeing it as less invasive and easier to administer in large herds. This becomes especially important for smallholder farms with limited labor.
Anyone managing animals for food production faces questions about drug residues and withdrawal periods. For milk producers and those marketing meat, monitoring withdrawal times after giving Oxyclozanide matters a great deal. Misjudging withdrawal can lead to costly losses if products test positive for residues. Established guidelines, which range from several days to weeks depending on the preparation and species, help set clear routines. Most producers see this as part of responsible management rather than a drawback, since the process is predictable and well understood by regulatory agencies and industry professionals.
People sourcing animal health products often find Oxyclozanide available in bulk powder form or pre-mixed oral drenches. Farm supply chains carry both, depending on regional regulations and preferences, meaning producers worldwide can usually access it with little trouble. While some operators prefer to mix their own formulations on-site, many opt for pre-registered products to ensure consistency and simplify record-keeping. The dry powder handles easily during both storage and dispensing, an asset for remote or under-resourced livestock operations. Regulatory controls govern every stage from manufacture to sale, giving reassurance about quality and compliance with safety standards.
Long-term outcomes in parasite control often depend on rotating products with different mechanisms and not overusing a single class. Resistance to fasciolicides has started to appear in several parts of the world. Unlike certain other drugs, widespread cases of Oxyclozanide resistance remain limited, especially when farmers rotate it with other compounds. Responsible use means dosing accurately by animal weight, treating only when necessary, and recording treatments for traceability. Veterinarians stress the value of regular fecal egg counts to monitor parasite levels, adjusting treatment strategies accordingly. Such habits help preserve the usefulness of all available products for years to come.
Demand for animal protein keeps climbing, yet every farmer faces pressure to hit production targets without overusing chemical inputs. Most recognize the need to balance parasite control with stewardship of both animal and environmental health. Oxyclozanide, with its narrow spectrum, minimizes non-target impacts and matches integrated parasite management principles. Careful selection reduces unnecessary treatments, saving money and benefiting wildlife that share grazing environments with livestock. Adopting such targeted strategies helps align traditional farming values with modern sustainability goals.
With two decades spent consulting on farms, I have seen treatments come and go. Some promise revolutionary results but fall short on practical points such as ease of use or farmer acceptance. Oxyclozanide earns respect because it fits into real-world routines. It does one job well—controlling adult flukes—without creating more complexity for already busy producers. Most cases of chronic fascioliasis in cattle or sheep see marked improvement following a properly timed course. Weighing the animals accurately before dosing prevents under- or overdosing, important for both effectiveness and cost control.
In several European dairy herds facing persistent liver fluke problems, standard treatments with wider-spectrum products led to resistance concerns and waning results. Shifting to Oxyclozanide twice yearly, timed after peak grazing risk, produced a marked drop in milk loss and fewer clinical cases in youngstock. Producers valued that they did not need to change much about daily routines—measure, administer, move on. Smallholder sheep farmers in wet upland regions reported similar results, seeing both an increase in lamb growth and improved ewe condition compared with years relying on single-drug programs. Such examples underline that practical, proven options remain vital even alongside new technology.
Mixed grazing systems on grassland create unique challenges for parasite control. In these systems, regular moves mean exposure to potential infection hotspots changes from week to week. Oxyclozanide fits well here; its ease of delivery works for batch treatments at sorting pens or on handling tracks. Its narrow action means producers can leave intervening treatments to target gut nematodes or other parasites with different compounds, reducing overreliance on any single group. In regions where land management encourages moist soils or standing water, coordinating fluke control with drainage improvement and grazing rotation helps break the cycle. It’s a reminder that animal health rarely depends solely on drugs—it rests on a whole system of good practice.
Regular users often point out that with products like Oxyclozanide, consistency trumps novelty. Controlled production methods result in a material with uniform texture, handling qualities, and predictable performance from one batch to another. This reliability softens the risks inherent in animal rearing. Veterinary authorities support its ongoing use for controlling Fascioliasis, and pre-market testing ensures compliance with strict residue limits. In practical terms, this means peace of mind—a valued asset for both small family farms and larger commercial operations.
Not every product suits every farm or every situation, and Oxyclozanide is no exception. Its activity focuses on mature stages only, requiring thoughtful timing to maximize benefit. In intensive systems with continuous grazing, opportunities for effective intervention can narrow, and missed cycles open the door for fluke damage. Some producers express concerns about taste in treated feed or short-lived inappetence after dosing, though most adjust administration methods to reduce problems. A handful of cases, particularly with goats or less common livestock species, need veterinary advice due to species-specific responses. These challenges remind anyone in the field that animal health management rewards attention to detail and communication with veterinarians.
The animal health sector leans on research to address resistance and optimize formulations. Studies continue to evaluate Oxyclozanide, looking at combined treatments, adjusted dosing, or integration with smarter diagnostics. Remote monitoring technology, such as automated weigh scales and health tracking, helps catch early signs of fluke infection. Advances like these raise the bar for all stakeholders. At ground level, producers want straightforward, economical tools that meet regulatory standards and stand up to real-world test. Oxyclozanide endures in the mix because it delivers on core requirements without excess fuss.
Animal welfare advocates and commercial farmers often find common ground in transparent, evidence-based practices. Oxyclozanide supports this balance by allowing routine fluke control—a major contributor to poor welfare when left unchecked—without unnecessary chemical load or environmental disruption. All treatments run under strict withdrawal rules, supporting both milk and meat safety for consumers. Regular communication between farmers, veterinarians, and suppliers helps address any emerging issues quickly, building trust across the production chain.
Producers who have relied on Oxyclozanide for decades offer candid accounts of its strengths and weaknesses. Success stories center on integration with grazing management, timely dosing, and working with local veterinarians to interpret diagnostic tests. Problems tend to arise from poor weight estimation or underestimating infection pressure, leading to disappointment and wasted effort. Sharing experiences across sectors—dairy, beef, small ruminant—builds community knowledge, with practical tips such as rotating water troughs or using risk maps to spot high-fluke paddocks.
The public's interest in food safety and animal health influences demand for certain treatments. Food exporters face mounting pressure to meet exacting residue standards and prove responsible use of veterinary medicines. Oxyclozanide, with its well-established safety record and clear labeling, helps producers meet these demands without jumping through complex hoops. Educating consumers about steps taken on-farm—including strategic use of established treatments—underscores shared goals of health and safety.
Farms rarely fight a single challenge at once. A practical program layers nutrient management, parasite control, housing improvements, and routine surveillance in a coordinated plan. Oxyclozanide plays its part as a reliable tool in this larger framework. Good communication between suppliers, veterinarians, and producers supports judicious use and helps anticipate supply or regulatory changes. Supply-chain bottlenecks or shifts in approved withdrawal periods require agility and clear messaging to minimize disruption.
Younger farmers and animal technicians inherit a landscape shaped by both tradition and innovation. For all the talk of breakthroughs and new molecules, the core challenge remains the same: keep animals healthy, production steady, and the environment protected. Oxyclozanide deserves a place in their toolbox not as a miracle cure, but as a proven aid in a wider, integrated management system. Listening closely to experienced neighbors and veterinarians, and weighing all options before acting, offers the surest route to both practical success and public trust.
Products like Oxyclozanide endure because they have earned the confidence of those who manage animals day in and day out. They deliver targeted results with a clear record behind them, fit into busy schedules, and offer flexibility across different systems. Achieving the right balance between parasite control, residue safety, and regulatory compliance calls for attention, skill, and willingness to adapt as circumstances change. In the ongoing effort to uphold health and productivity on the farm, practical measures—evidence-based, accessible, and proven over time—will always claim their place as essentials.