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HS Code |
405958 |
| Cas Number | 108-39-4 |
| Chemical Formula | C7H8O |
| Molecular Weight | 108.14 g/mol |
| Appearance | Colorless to yellowish liquid or solid |
| Odor | Phenolic |
| Melting Point | 11.8°C |
| Boiling Point | 202°C |
| Density | 1.03 g/cm³ (at 20°C) |
| Solubility In Water | 22 g/L (at 25°C) |
| Flash Point | 86°C |
| Vapor Pressure | 0.11 mmHg (at 25°C) |
| Pka | 10.09 |
| Refractive Index | 1.539 (at 20°C) |
| Synonyms | 3-Methylphenol, m-Hydroxytoluene |
| Un Number | 2076 |
As an accredited M-Cresol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 500 mL amber glass bottle with a secure cap, labeled "M-Cresol," featuring hazard warnings, supplier information, and batch details. |
| Shipping | M-Cresol should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled with hazard warnings. It must be transported as a hazardous material, complying with relevant regulations (such as DOT, IMDG, or IATA). Keep away from incompatible substances, heat, and ignition sources. Ensure adequate ventilation during handling and use appropriate protective measures. |
| Storage | M-Cresol should be stored in a tightly closed, clearly labeled container, in a cool, dry, and well-ventilated area away from heat, sparks, and open flames. Keep away from incompatible substances such as strong oxidizers and acids. Store at room temperature and protect from light. Use corrosion-resistant containers, and ensure proper local exhaust ventilation to prevent vapor accumulation. |
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Purity 99.5%: M-Cresol with 99.5% purity is used in the synthesis of agrochemical intermediates, where it ensures high yield and minimal impurities in the final product. Melting point 11.8°C: M-Cresol with a melting point of 11.8°C is used in resin manufacturing, where it delivers consistent polymerization under controlled conditions. Stability temperature up to 200°C: M-Cresol with stability temperature up to 200°C is used in metal degreasing solvents, where it maintains solvent integrity under thermal stress. Viscosity 3.9 cP: M-Cresol with a viscosity of 3.9 cP is used in electronics photoresist formulations, where it allows precise pattern definition and smooth coating. Molecular weight 108.14 g/mol: M-Cresol with a molecular weight of 108.14 g/mol is used in pharmaceutical synthesis, where it provides predictable reactivity in metabolic intermediates production. Water content <0.05%: M-Cresol with water content below 0.05% is used in the formulation of antioxidants, where it minimizes hydrolysis and improves product shelf life. Low sulfur content: M-Cresol with low sulfur content is used in lubricant additive production, where it prevents catalyst poisoning and enhances final product purity. Flash point 87°C: M-Cresol with a flash point of 87°C is used in ink manufacturing, where it ensures safer handling and controlled evaporation rates. |
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M-Cresol often stands out in conversations around specialty chemicals, and not without reason. With a clear history of use in multiple industries, this compound has built a reputation for versatile applications. In daily work across labs and factories, M-Cresol pops up as a key component that helps get things done—whether in synthesis, preservation, or as part of a broader chemical process. Its chemical formula, C7H8O, seems simple, yet the impact of one methyl group attached to a phenol ring reaches far beyond that basic structure. Many who work with it recognize its potent character almost immediately: a slightly medicinal smell, a tendency to color when exposed to light and air, and a consistency that signals both reliability and potential hazards if not respected.
Talking about specifications, it pays to get hands-on. Not every batch of M-Cresol is the same; purity levels make a real difference in what happens downstream. For those of us who handle procurement and process planning, seeing purity levels listed as 98% or greater tells something about how well it will perform in reactions. Impurities, even in trace amounts, can change yields or complicate separation steps. Specific gravity and boiling point—two figures that often land on technical sheets—aren’t just numbers on paper. In practical settings, knowing M-Cresol boils at about 202°C means having the right controls during distillation or when designing a reaction that needs tight thermal management.
Storage and packaging deserve their own mention here. Labs or shops working with M-Cresol keep it sealed, shielded from heat and sunlight to keep the contents stable. The tendency of cresols to oxidize and darken—not just cosmetic but indicative of chemical changes—reminds us why keeping tanks or bottles airtight really matters. There’s also a safety dimension: concentrated cresols have a biting impact on skin and respiratory systems, so anyone handling it pays attention to gear and good ventilation. Decades of accident reports and occupational health guidelines reinforce that caution.
M-Cresol earns its spot on the shelf largely thanks to its solid track record in manufacturing and science. The compound steps up in making resins, where it acts as both raw material and catalyst. Bakelite, one of the earliest plastics, relies on cresols during its formation. In the pharmaceutical sector, M-Cresol pulls double duty: as a preservative for injectable drugs and as a building block for synthesizing antiseptics and disinfectants. My own routine involvement in quality control has shown that finding the right balance of M-Cresol in a formulation can keep products free from microbial growth without compromising the stability of the main ingredients. This is especially important in medications like insulin, where preservation cannot mess with efficacy.
Looking at electronics, the story shifts a bit. M-Cresol gets called into service producing circuit board laminates and photoresist materials. In clean rooms and fabrication plants, staff rely on its stability and reactivity to help craft layers that insulate or protect delicate designs. Energy storage applications aren’t left behind either—different forms of cresol derivatives contribute to improved electrolytes and battery performance. For those making these advanced materials, the consistency in M-Cresol’s behavior means fewer surprises and smoother production runs, which can translate to less waste and more predictable cost structures.
In agriculture, companies convert M-Cresol into herbicidal and fungicidal agents. The versatility means that a single drum can ultimately be transformed into products that safeguard crops or disinfect greenhouses. This is a clear reminder that progress in crop protection isn’t just about finding new molecules, but also about using well-known compounds efficiently and responsibly.
At a glance, cresols might blur together, but the M-Cresol variant holds characteristics that don’t quite line up with its sister compounds, ortho- and para-cresol. The meta arrangement of the methyl group, placed at the third position on the ring, influences both solubility and reactivity. This shapes what happens in real-world use. For example, the melting and boiling points differ from those of ortho- or para-cresol, dictating how engineers choose between these compounds for specific jobs. In applications demanding high purity and consistent chemical behavior—semiconductors come to mind—M-Cresol often becomes the preferred option.
This is not to say that ortho- and para-cresol don’t have their own fans. Each has carved out its own niche. Para-cresol, for instance, shows up more in antioxidants and fragrance intermediates thanks to its slightly sweeter scent and a different profile of chemical stability. Ortho-cresol gets tapped for use in fungicides and as a precursor to some dyes. But switch back to preservatives, resin synthesis, or high-purity electronics mixtures, and the evidence supports M-Cresol’s unique fit.
My years in specialty chemicals have been shaped by seeing both the strengths and the disadvantages of cresols firsthand. Research papers back up the value M-Cresol brings, citing its efficiency as a bacteriostatic agent and its critical part in resin formation. Chemists appreciate that M-Cresol’s particular molecular structure often leads to cleaner reaction pathways in polynuclear aromatics and resins. Environmental specialists also watch M-Cresol closely. Regulatory agencies—like the US Environmental Protection Agency and international consortia—track usage, emissions, and residues, since cresols can persist and show toxicity to aquatic life if improperly discarded.
Experience shows that most companies using M-Cresol have settled into routines based on deep evidence. For every kilogram purchased, there’s usually a trail of documentation explaining the purity, the handling precautions, and the waste management steps. This isn’t just bureaucracy; it’s a feedback loop that encourages safer, more sustainable work. Whenever demands rise for greener chemistry, teams revisit long-trusted chemicals like M-Cresol and ask whether processes can evolve—maybe through better reclamation, maybe with safer substitutes, or by fine-tuning dosing levels to cut waste.
Hazards come with territory. M-Cresol is acutely toxic if inhaled, ingested, or absorbed through the skin. Even brief contact can lead to severe discomfort or injury. In high school labs, this would be enough for teachers to lock it away, but in industry and research, risk gets managed with engineering controls and personal protective equipment. Over the years, I’ve seen a big shift in how workplaces approach health and safety. Decades ago, people sometimes took shortcuts, but after enough near-misses and a stronger regulatory environment, protocols are stricter: fume hoods, gloves, regular spill containment drills. Training on emergency response for cresols now sits alongside lessons in chemical reactivity.
Beyond safety, environmental factors need attention. Improper disposal leads to contamination in water supplies, and breakdown products have a reputation for resilience in soils and sediments. Responsible companies don’t just stop at permits and paperwork; they run their own audits and invest in waste treatment tailored for cresols. I’ve been called in for site inspections where every drum and pipeline has a clear, signed chain of custody. This shows not only the seriousness of the risks, but also a growing culture of stewardship.
Sometimes, clients ask if there’s a way to skip M-Cresol altogether. The answer depends on the process. In some resin formulations, companies trial phenol or other cresol isomers. These can work, but rarely match the performance or cost profile exactly. Green chemistry initiatives explore bio-based phenolics or biodegradable alternatives, yet most pilot-scale results fail to deliver the durability needed in modern electronics or medical packaging.
Digital tools and predictive modeling begin to play a larger role. Screening potential substitutes for similar solubility, volatility, and reactivity profiles helps identify possible candidates, but running real-world tests often brings surprises. Every time a promising candidate comes along, it faces tough scrutiny—not just for how it performs in the lab, but for total health, environmental, and lifecycle impacts. Experience tells us: progress is slow, but the search continues.
Regulators keep close tabs on M-Cresol. It appears under chemical inventories and controlled substance lists in North America, Europe, and Asia. Import and export require detailed documentation, and users invest in compliance systems that track purchasing, on-site handling, and disposal. From my work on global teams, navigating these regulations isn’t just about checking boxes. Customs, environmental monitoring, and downstream reporting systems create a web making sure every shipment lines up with local and international standards.
Quality management shapes the way M-Cresol appears in finished goods. A device manufacturer, for instance, needs proof that every shipment meets agreed limits on residual solvents, heavy metals, and color. Batches are tested with GC-MS and HPLC methods rather than relying on assumptions. When mishaps happen—such as off-spec material triggering product recalls—the cost and impact ripple outward fast. Lessons learned from these moments highlight not only the chemical’s power, but the need for vigilance across logistics, manufacturing, and compliance teams.
Curiosity grows about what role classic chemicals play in the age of AI, automation, and rapid supply chain changes. The COVID-19 pandemic and resulting shifts in global logistics showed that stable, well-documented chemical supply chains let industries keep running when surprises hit. M-Cresol—familiar, traceable, and reliable—allowed for easier pivoting during setbacks in raw material procurement. The digital transformation has brought more transparency to these supply chains. Online databases, real-time inventory monitoring, and remote compliance auditing became regular parts of managing the lifecycle of cresol-based products.
For smaller producers, digital access also levels the field. Being able to tap into global best practices, review hazard and handling data, or even join webinars on emission management helps more companies handle chemicals like M-Cresol safely. The knowledge gap narrows when trainers, consultants, and safety officers can share up-to-date, evidence-based guidance across borders. This trend promises improved safety, higher product quality, and stronger sustainability all the way down the line.
Working with a chemical as potent and multi-faceted as M-Cresol throws up communication challenges. End-users, regulators, advocacy groups, and non-specialists all have legitimate questions—about health, about supply, about sustainability. Open communication helps build trust, especially when companies share updated safety data, emissions reports, and results of process optimization. On the ground, employees appreciate access to clear training materials, exposure controls, and practical troubleshooting advice based on actual experience, not just textbook warnings.
Community relationships come into play for facilities sited near neighborhoods, water systems, or public spaces. Holding open houses, publishing environmental performance summaries, and responding quickly to local concerns shows respect for neighbors and builds credibility long-term. Missteps in cresol management historically damaged community trust, and it takes consistent good practice to rebuild. As environmental expectations grow and public scrutiny sharpens, companies work harder to turn past lessons into better future outcomes.
Sustainability in specialty chemicals shares some common struggles. Sourcing feedstocks—often from fossil-based phenolics—raises bigger conversations about supply chain ethics, emissions, and end-of-life waste. Wastewater treatment stays front and center, since cresol-laden discharges threaten aquatic life if improperly treated. Over the past decade, investment in closed-loop processes, more efficient catalytic systems, and better on-site remediation made a visible dent in emissions and waste. Leading organizations take a life-cycle view and run pilot projects to reclaim and reuse spent cresol or convert it into less problematic forms.
Some solutions emerge through cross-sector partnerships. Collaboration between chemical makers, downstream users, and environmental researchers spurs innovation—sometimes yielding advances like more effective adsorbent materials for wastewater or developmental pilot plants that convert waste cresol into value-added products. Financial incentives for cleaner production, coupled with transparent reporting standards, push companies to do better. From personal involvement, the most promising projects happen where technical, regulatory, and community insights blend together—ensuring gains in one area don’t inadvertently trigger setbacks elsewhere.
Every year, new entrants to chemical manufacturing need training and upskilling. Handling M-Cresol introduces concepts that reach beyond safety: understanding chemical compatibility, monitoring air quality, running analytical tests, and interpreting process deviations. Learning from real events—minor spills, quality audits, customer feedback—gives new engineers, operators, and quality staff a direct sense of the compound’s properties and what’s at stake if controls fail.
Partnerships with universities, trade schools, and regulatory bodies bring fresh perspectives. Internships and continuing education programs that incorporate hands-on work with cresols deepen practical understanding and give companies a pool of candidates ready to meet modern challenges. This expanding emphasis on workforce preparation, transparency, and scientific literacy holds value for the entire industry and the public that relies on safe, high-quality products.
M-Cresol sits at an interesting junction between legacy chemistry and modern industrial demands. In an era where sustainability, transparency, and product performance all matter, it faces plenty of scrutiny, but also ongoing demand. Technical advantages—broad reactivity, reliable preservation, and diverse downstream pathways—keep it in regular use from pharmaceuticals to electronics. Handling challenges and risks doesn’t lessen its value; rather, these aspects reinforce the importance of careful management and continuous improvement.
Maintaining a balance between technical needs, safety measures, and long-term environmental goals isn’t easy. Those working with M-Cresol—procurement teams, operators, researchers, compliance officers—share responsibility for making sure the benefits outweigh the potential drawbacks. As regulations, customer demands, and community expectations evolve, so too must the ways we source, transport, use, and eventually dispose of this compound. Drawing on decades of past experience, rigorous science, and a willingness to change when better options emerge will point the way for those who rely on M-Cresol and those who live with its wider impacts.