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m-Anisic Acid

    • Product Name m-Anisic Acid
    • Alias p-Methoxybenzoic acid
    • Einecs 202-618-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    812590

    CAS Number 536-90-3
    IUPAC Name 3-methoxybenzoic acid
    Molecular Formula C8H8O3
    Molecular Weight 152.15 g/mol
    Appearance White crystalline powder
    Melting Point 106-108°C
    Boiling Point 275°C (decomposes)
    Solubility in Water Slightly soluble
    Density 1.234 g/cm³
    Odor Odorless or faint aromatic odor

    As an accredited m-Anisic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Brown glass bottle containing 100 grams of m-Anisic Acid, labeled with product details, hazard symbols, and tightly sealed screw cap.
    Shipping m-Anisic Acid should be shipped in tightly sealed containers, protected from moisture and direct sunlight. The chemical must be handled with care, following safety regulations for organic acids. Transport should comply with relevant hazardous material guidelines, ensuring proper labeling and documentation during shipping to prevent spills, exposure, or environmental contamination.
    Storage **m-Anisic acid** should be stored in a tightly sealed container, away from moisture, heat, and direct sunlight. Keep it in a cool, dry, well-ventilated area, separate from incompatible substances such as strong oxidizing agents. Avoid sources of ignition. Proper chemical safety labeling and secondary containment are recommended to prevent accidental spills or exposure.
    Application of m-Anisic Acid

    Applications of m-Anisic Acid in Industrial Manufacturing

    As a specialized manufacturer of m-Anisic acid, we supply consistent, high-purity material for diverse industrial sectors. Downstream industries integrate this intermediate into production lines according to rigid compliance and precise process protocols. Below, we outline key real-world downstream applications with precise technical details for manufacturing professionals.

    1. Fragrance and Aroma Chemicals

    Aromatic aldehyde and ester synthesis frequently relies on m-Anisic acid as a controlled intermediate, especially in the production of fine fragrances and complex aroma blends. Its stability under elevated temperatures and ease of esterification suit scale-up processes for both mass market and specialty perfumery. Leading manufacturers use direct methylation or reduction of m-Anisic acid to develop olfactives with stable and reproducible performance. The raw material’s compatibility with automated dosing and closed-system handling safeguards product quality from batch to batch.

    Industry compliance standards

    • International Fragrance Association (IFRA) Standards
    • REACH (Registration, Evaluation, Authorization and Restriction of Chemicals), EU
    • Cosmetic Ingredient Review (CIR), US FDA
    • ISO 9235: Natural Aromatic Raw Materials

    Typical usage ratio

    • 3%–12% (w/w) in fragrance intermediates; variable according to the blend and target olfactory family. Major manufacturers adjust between 5% and 15% for color, odor threshold, and finished lot consistency.

    Downstream process integration

    • Introduced during aldehyde synthesis prior to final blending, typically in multi-step batch reactors, with automated metering and high-shear mixing.

    Final product types

    • Fine perfumes and eau de toilettes
    • Household and industrial fragrances
    • Detergent perfume bases
    • Personal care aroma additives

    2. Pharmaceutical Intermediates

    API manufacturers use m-Anisic acid as a synthetic building block in the preparation of non-steroidal anti-inflammatory drugs and anti-infective agents. Under GMP manufacturing, control of impurity profile and traceability begins with the sourcing of high-purity raw acid, usually validated by HPLC and heavy metal testing. Synthesis protocols demand reliable reactivity and compatibility with hydrogenation, amidation, or halogen substitution steps depending on the target molecule.

    Industry compliance standards

    • United States Pharmacopeia (USP)
    • European Pharmacopoeia (Ph. Eur.)
    • ICH Q7 GMP Guide for Active Pharmaceutical Ingredients
    • Drug Master File (DMF) registration requirements for intermediates

    Typical usage ratio

    • 1.5–8 mol% relative to the main reactant in each synthesis cycle; titration adjustments align with downstream molecule molar yield and purification yield.

    Downstream process integration

    • Fed as the starting carboxylic acid in protected synthesis or amidation step, using jacketed glass-lined reactors, with in-line purity monitoring before proceeding to further transformations.

    Final product types

    • Phenolic anti-infective pharmaceutical APIs
    • Analgesic intermediates
    • Antipyretic drug intermediates
    • Bulk pharmaceutical chemicals for further modification

    3. Food Flavors and Additives

    Process flavor and food additive firms employ m-Anisic acid in the manufacture of certified food flavor esters and aroma-active compounds. The material’s distinct sweet, aniseed-like notes enhance fruit, spice, and vanilla profiles. Adherence to food-grade quality benchmarks—validated microbial limits and absence of prohibited substances—is required for both global and regional formulation dossiers. Complete traceability documentation supports customer audits and regulatory notifications.

    Industry compliance standards

    • Food Chemicals Codex (FCC)
    • GRAS (Generally Recognized as Safe) status, US FDA
    • EU Regulation No 1334/2008 (flavorings and source materials)
    • HACCP and ISO 22000 food safety management systems

    Typical usage ratio

    • 0.01%–0.10% (w/w) as component of flavor base or premix; higher concentrations require adjustment according to sensory threshold and regulatory maximum levels for end-use application.

    Downstream process integration

    • Blended in closed flavor reactors downstream from filtering, typically during esterification or as part of solvent-free flavor concentrate pre-mix manufacturing with in-process gas chromatography validation.

    Final product types

    • Fruit and spice flavor concentrates
    • Sweet bakery and dairy flavorings
    • Confectionary and beverage flavor additives
    • Compound flavors for instant foods

    4. UV Absorber and Polymer Additive Synthesis

    Major resin and polymer manufacturers utilize m-Anisic acid as an essential intermediate in the production of certain benzotriazole UV absorbers and stabilizers intended for coatings, plastics, and films. Quality requirements focus on low color index and controlled purity to avoid polymer haze and to ensure end-use optical clarity. Sophisticated esterification and cyclization processes rely on batch-to-batch consistency and fast, residue-free conversion under nitrogen or inert atmospheres. Process streams often include in-line filtration to manage particulate control.

    Industry compliance standards

    • REACH Regulation, EU, Annex XVII for polymer additives
    • ASTM D5208-01: Practice for Fluorescent UV Exposure of Photodegradable Plastics
    • RoHS Directive 2011/65/EU for electronic and consumer goods polymers
    • ISO 14001 Environmental Management for additive production

    Typical usage ratio

    • 5%–18% (w/w) in UV absorber synthesis steps; loading rate depends on target molecular structure and resin compatibility. Industrial transition to higher ratios possible in high-performance automotive and agricultural film sectors.

    Downstream process integration

    • Charged to reactor as an acid precursor during the first condensation or esterification stage, followed by sequential solvent stripping, filtration, and drying prior to blending into masterbatch or direct compounding.

    Final product types

    • Benzotriazole and phenolic UV absorbers
    • Stabilizer masterbatches for plastic extrusion
    • Coating and film stabilizers
    • Automotive, construction, and packaging polymers

    5. Agrochemical Intermediate Manufacturing

    Crop protection and plant growth regulator manufacturers source m-Anisic acid as a building block for tailored, regulated agrochemical active ingredients. Quality control spans not only purity but also trace pesticide and heavy metal limits, meeting stringent registration submission requirements. Specific synthetic routes require robust raw material transfer protocols and efficient conversions for cost efficiency and traceability throughout the value chain.

    Industry compliance standards

    • FAO/WHO specifications for pesticide ingredients
    • ISO 17025 accredited testing methods for impurities
    • OECD Guidelines for the Testing of Chemicals
    • REACH Regulation, EU, for agricultural intermediates

    Typical usage ratio

    • 2–10% by mass depending on target molecule yield; formulation labs optimize based on conversion efficiency and environmental residue minimization targets.

    Downstream process integration

    • In-circuit dosing during the first or second synthetic intermediate stage, frequently involving chlorination, amidation, or etherification, followed by neutralization and solvent recycling for closed-system compliance.

    Final product types

    • Herbicide intermediates
    • Growth regulators
    • Specialty pesticide active intermediates
    • Seed treatment compound building blocks

    6. Dye and Pigment Intermediate Synthesis

    High-performance dye manufacturers use m-Anisic acid as a directed intermediate in azo dye and metal complex pigment production for textiles and specialty plastics. Precise acid value and lightfastness performance start from raw material quality, with close management of aminomethylation and coupling reactions. Supply traceability, batch impurity logs, and certified color indices form the basis for wide textile and plastics industry acceptance.

    Industry compliance standards

    • Oeko-Tex Standard 100 for textile chemicals
    • ISO 9001:2015 for pigment and dye production
    • ZDHC MRSL for restricted substance compliance
    • REACH SVHC monitoring for pigment intermediates

    Typical usage ratio

    • 5–20% (w/w) in intermediate dye formulations; setpoint based on final dye class, solubility, and light fastness targets with routine QC evaluation.

    Downstream process integration

    • Added to sulfonation or diazotization stage, with process intensification via continuous flow or multi-stage batch, listed in material batch records for downstream traceability.

    Final product types

    • Disperse and acid dyes for synthetic fibers
    • Metal-complex and direct dyes
    • High-stability plastic pigments
    • Ink and coating colorants
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    Certification & Compliance
    More Introduction

    m-Anisic Acid: Reliable, Efficient, and Trusted Ingredient from Our Factory

    Quality from a Manufacturer’s Perspective

    At our production site, m-Anisic Acid, also known as 3-methoxybenzoic acid, draws on decades of expertise in aromatic acid synthesis. Every kilo that leaves our warehouse reflects a firm commitment to consistency, process control, and traceability. Working directly with the raw materials and overseeing the entire process, we have seen firsthand how attention to detail brings value to downstream industries—be it personal care, pharmaceuticals, or fine chemicals.

    Our product comes in bright white crystalline powder form, with a purity that regularly exceeds 99%. We batch-test each lot to ensure minimal traces of impurities; this approach helps downstream formulators avoid the headaches of residual solvents, off-odor, and by-products that can plague applications sensitive to color or scent. m-Anisic Acid at our plant follows strict in-house procedures, targeting careful pH management to avoid discoloration and caking, plus real-time monitoring of reaction parameters to keep the methoxy group intact. As a chemical manufacturer, we have learned the lesson many times: the smallest deviation in processing can lead to troublesome inconsistencies, which can then cascade through an entire value chain.

    Meeting Diverse Industry Demands

    From the fine chemistry floor to high-volume personal care producers, requests for customization and technical support arrive every week. Our m-Anisic Acid finds most demand in the fragrance, cosmetic preservative, and pharmaceutical sectors. In perfumery, it acts as a mild fixative and boosts sweet, warm notes when blended with esters. In skin care and cosmetic formulations, it demonstrates an ability to inhibit microbial growth, giving developers a plant-inspired alternative to synthetic preservatives. Many formulators appreciate the natural sourcing potential of our product: our process relies on starting from renewable anisole, not fossil-based foundations.

    Pharmaceutical customers have highlighted m-Anisic Acid’s value both as an intermediate and as a building block for more complex molecules. The methoxy group at the meta position allows selective downstream modifications that cannot be easily achieved with para- or ortho-isomers. We support scale-up and documentation for regulated markets, including DMF registration data and full traceability of supply lines for cGMP production lines.

    Specification That Goes Beyond the Sheet

    In many chemical industries, a certificate of analysis only tells part of the story. Our experience shows that batch-to-batch transparency, clear knowledge about elemental impurities, and robust supply continuity make the difference in maintaining a competitive edge. The m-Anisic Acid produced here boasts a melting point typically between 106°C and 110°C, confirming its purity and ensuring easy integration into existing plant protocols. Moisture content is kept under 0.2%, keeping flows smooth during storage and minimizing agglomeration in climate-variable regions.

    With solubility topping 2 g/L in ethanol and modest solubility in water, the product meets requirements for formulations needing solvent switching. Another frequent concern—heavy metal contamination—never slips our radar. We screen and control lead, cadmium, and arsenic levels to below detection by commonly recognized methods. Our plant-anchored technical staff works directly with customers to interpret analytical data and resolve process tweaks, as often problems and micron-scale inconsistencies demand more than a specification sheet can capture.

    Differences That Matter—Not All m-Anisic Acid Is the Same

    Direct involvement with synthesis brings a perspective often missing from generic or traded m-Anisic Acid. Batches sourced from resellers and trading houses tend to carry drifting quality. End-users sometimes report unpredictable color shifts in creams or off-odors in fragrance concentrates. Our manufacturing controls limit oxidation and unwanted side reactions, avoiding the phenolic impurities that develop during uncontrolled processing or long-temperature holds. These by-products may not affect a synthesis but can cause end-use concerns in premium cosmetics.

    We source our feedstocks with a long view, so no sudden changes in starting material or unexpected off-notes from varied anisole suppliers. By deeply understanding the chemical lifecycles, we can troubleshoot foam formation, pH drift, and off-gassing that have frustrated both plant operators and formulation chemists. Customers working with competitor samples report less predictable behavior in emulsion stability and less shelf-life than batches from our line.

    Environmental Stewardship and Sustainability Practices

    As a process-intensive manufacturer, waste reduction and process optimization remain top priorities. Our synthesis route for m-Anisic Acid is developed around atom economy and solvent minimization. Closed-loop solvent recovery and in-process recycling shave costs while reinforcing our commitment to lower environmental impact. On-site effluent treatment ensures purification of process water and prevents phenolic residues or aromatic emissions from escaping into local waterways. We invite regular local inspections and contribute to regional air and water monitoring. Many buyers in personal care and pharma ask for data on origin, processing, and process by-products. We deliver transparent reports and third-party audits upon request.

    Many customers express concern over supply-chain resilience and carbon footprint. By focusing on on-site energy integration—waste heat recovery and improved energy scheduling—our plant reduces overall emissions and improves efficiency without sacrificing product quality.

    Traceability, Support, and Responsiveness

    Direct manufacturing lets us track every shipment down to the hour it left our warehouse. We implement full batch coding and retain production samples for years. This supplies a clear, auditable trail in case of quality or regulatory reviews. Multiple buyers have approached us after dealing with inconsistent product from brokers—especially where documentation has lapsed or samples could not be traced back to a defined process or origin. With every batch of m-Anisic Acid leaving our warehouse, technical documents and analytical files are always at hand. Regulatory compliance runs as a live process, with staff engaged in global chemical compliance registrations and regular internal audits.

    Our team fields technical calls directly—without the bottlenecks of agencies or third-party traders. Troubleshooting an emulsion crash, clarifying regulatory filings, or reviewing an unknown impurity—all handled here, in-house. We have supplied m-Anisic Acid to manufacturers who must meet the strictest EU and North American regulatory thresholds. With every new inquiry, we make no compromise on analytical disclosure and encourage open visits to our production site. Responsible supply chains go beyond standard paperwork; real-world reliability in personal care and pharmaceutical applications is built on consistent, prompt response from the manufacturer.

    Why Application Experience Matters

    Our knowledge does not stop at synthesis. Over years of partnering with customers across the pharmaceutical, fragrance, and cosmetic fields, the lessons learned become part of how we refine our processes. Some perfume creators ask for specific particle size ranges to blend seamlessly into their concentrates; our team knows how to tweak grinding parameters to avoid static clumping or formulate to avoid dissolution issues in challenging solvents.

    For customers trialing preservative systems, stability under varying pH and humidity matters—our product supports extensive accelerated testing programs. Staff here consult with application laboratories to share tips on avoiding interactions with other formulation ingredients and offer hands-on advice for integrating m-Anisic Acid into established base formulas.

    Tailored support has meant troubleshooting temperature-sensitive reactions in pharma intermediates, co-developing new solubilizer blends for cleanse-off formulations, and even supporting custom crystal modification requests for unusual solvent systems. Every plant manager knows that not all technical questions can be answered by documents alone. Our practice comes from the real troubleshooting that follows the product all the way from synthesis to the end-user’s factory floor.

    Why We Recommend m-Anisic Acid: Our View from the Plant Floor

    With growing pressure on formulators to phase out harsh preservatives and seek greener alternatives, m-Anisic Acid brings tangible benefits. The safety profile and mildness, combined with proven antimicrobial effect, justify its growing presence on ingredient lists across high street and premium cosmetic brands. By manufacturing the product directly, we ensure strict batch separation—avoiding cross-contamination with structurally similar, but less desirable, benzoic or salicylic acids that may bleed through shared production lines at lower-tier plants.

    m-Anisic Acid may compete with relatives like p-Anisic Acid or o-Anisic Acid, but the meta positioning of the methoxy group creates unique physicochemical properties. The product’s moderate acidity enhances stability in multiple pH ranges, offering excellent compatibility from personal care liquids to lotions, gels, and fine fragrance hold-outs. We have examined the minute differences that crop up in solubility curves, reactivity in esterification, and compatibility with natural oils; our advice is based on comparative, hands-on trials rather than theoretical speculation.

    We have seen formulations move from idea to factory-scale output, with m-Anisic Acid reliably outperforming lower-purity or brokered material. Smarter processing, improved shelf-life, and enhanced sensory profiles come from controlled raw materials, thorough documentation, and close technical partnership between the end-user and us, the direct producer.

    Chemical Safety In Practice

    Having direct oversight of m-Anisic Acid synthesis means chemical safety is never an afterthought. Workplace monitoring, strict PPE standards, and environmental monitoring are part of our daily routine. Regular safety drills and engagement with local authorities ensure ongoing compliance with regulatory frameworks, domestic and international.

    End-use safety matters at every stage, from handling small lab jars to loading bulk containers. All handling recommendations consider observed risks during loading, transfer, and packaging. Real lessons from the plant floor—temperature swings, moisture exposure, and pressure management—inform every stability and hazard statement. It is not enough to meet minimum standards; our commitment is ensuring every downstream customer inherits a safe, usable material.

    Logistics: Reliability Rooted in Real Production

    Logistics tie every stage together. Our direct manufacturing model means we always know where every pallet is on the journey from our warehouse to the customer’s door. We select packaging solutions based on practical storage conditions and climatic risks—not just cost—because we have seen what a few hours in uncontrolled heat can do to sensitive aromatic acids.

    We work with logistics partners experienced in chemical freight, updating them on legislative changes in destination markets. All shipments come with the product data, handling guides, stability records, and regulatory papers you expect from a primary source. If a customer runs into a customs bottleneck or needs expedited delivery, our plant logistics coordinators step in—no waiting for broker relay.

    Customer-Focused Innovation

    In-house research and pilot production stretch the boundaries of m-Anisic Acid’s potential. Recent collaborations with specialty chemical users have led to new grades—reduced particle size for rapid dissolution, or extra-low residue for premium skin care applications. We do not wait for requests to drive innovation; our technicians document trends and technical hurdles in real-world scenarios and feed discoveries back into plant improvements.

    Input from our own lab and feedback from customer technical teams keep product development a living process. Whether it is a request for unique packaging to support high-humidity warehousing or support for a regulatory submission in a new national market, our staff brings direct, practical solutions backed by years of production familiarity.

    Conclusion: Built on Trust, Experience, and Commitment

    Making m-Anisic Acid is not only about technical data or purity numbers. Our factory’s track record stands on real-world performance, honest technical support, and open communication about capabilities and limitations. We believe the difference between a successful product and a persistent headache comes down to supplier reliability and manufacturing know-how.

    From start to finish, we support those who rely on m-Anisic Acid—ensuring they get a material that works as hard and as reliably as they do.