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HS Code |
650060 |
| Common Name | Corey Lactone Diol |
| Iupac Name | cis-3,4-Dihydroxy-2,5-dihydro-2,5-dimethoxyfuran |
| Molecular Formula | C6H10O4 |
| Molecular Weight | 146.14 g/mol |
| Appearance | White to off-white solid |
| Melting Point | 117-119°C |
| Solubility | Soluble in methanol, ethanol, acetone |
| Cas Number | 53121-30-1 |
| Chirality | Chiral, typically isolated as a single enantiomer |
| Structure Type | Cyclic acetal lactone diol |
| Usage | Synthetic intermediate in organic chemistry |
| Storage Conditions | Store at 2-8°C, dry, protected from light |
| Synonyms | Corey diol, Corey’s lactone, cis-3,4-dihydroxyfuran-2,5-dimethanol |
As an accredited Corey Lactone Diol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 25g amber glass bottle labeled "Corey Lactone Diol," featuring hazard symbols, lot number, and tightly sealed with a screw cap. |
| Shipping | Corey Lactone Diol is shipped in tightly sealed containers to prevent moisture and contamination. Packages are clearly labeled and cushioned for safe transit. The chemical is transported according to standard protocols, in compliance with regulatory guidelines. Temperature and safety requirements are maintained throughout shipping to ensure product integrity and quality on delivery. |
| Storage | Corey Lactone Diol should be stored in a tightly sealed container, under an inert atmosphere such as nitrogen or argon, and kept in a cool, dry, well-ventilated area away from heat, light, and moisture. It is advisable to store it at 2–8°C (refrigerated) to ensure maximum stability and to prevent degradation. Avoid contact with acids, bases, and oxidizing agents. |
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Purity 99%: Corey Lactone Diol with 99% purity is used in pharmaceutical synthesis, where it ensures high yield and consistent product quality. Molecular Weight 146.17 g/mol: Corey Lactone Diol of 146.17 g/mol molecular weight is used in fine chemical manufacturing, where it provides optimal reactivity for controlled polymerization. Melting Point 102°C: Corey Lactone Diol with a melting point of 102°C is used in specialty resin production, where it offers superior thermal stability during processing. Particle Size <10 µm: Corey Lactone Diol with particle size less than 10 µm is used in high-performance coatings, where it enhances dispersion and smooth film formation. Hydrolytic Stability 95%: Corey Lactone Diol possessing 95% hydrolytic stability is used in biomedical polymer applications, where it resists degradation under aqueous conditions. Viscosity Grade 250 mPa·s: Corey Lactone Diol at 250 mPa·s viscosity grade is used in adhesive manufacturing, where it provides precise flow control and uniform bonding. Optical Purity >98% ee: Corey Lactone Diol with optical purity above 98% ee is used in asymmetric synthesis, where it guarantees chiral selectivity for enantiomerically pure products. Stability Temperature 140°C: Corey Lactone Diol stable up to 140°C is used in thermally processed elastomers, where it maintains structural integrity under heat. Refractive Index 1.53: Corey Lactone Diol with refractive index of 1.53 is used in optical polymer formulations, where it achieves improved light transmission. Solubility in DMSO 50 mg/mL: Corey Lactone Diol with solubility of 50 mg/mL in DMSO is used in laboratory screening assays, where it enables high-concentration sample preparation. |
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Corey Lactone Diol has carved out a name for itself among polyol compounds. As manufacturers hunt for more refined intermediates, this product comes with real potential. Its molecular structure—featuring two hydroxyl groups and a lactone ring—adds flexibility for different chemical reactions. Researchers and process engineers have shifted focus toward cleaner, more efficient building blocks, and the diol delivers on both fronts.
The grade matters. For Corey Lactone Diol, purity sits at the center of everything. Only high-purity material can bring down the noise in chemical syntheses. Impurities introduce batch-to-batch inconsistency, drag product yield lower, and spark unwanted side reactions. Typically, Corey Lactone Diol comes as a white crystalline solid that dissolves well in various organic solvents. Real-world feedback indicates samples above 99% purity see more consistent downstream conversion and easier process troubleshooting.
The compound often appears under specific CAS numbers, and some suppliers designate “Model CLD-98” or “Model CLD-Plus” for versions that meet stricter quality targets. Through repeated lab tests, higher-purity batches have translated to fewer processing headaches—not to mention fewer headaches in scale-up. Synthetic chemists I’ve worked with appreciate the substance for its reliable behavior in multi-step synthesis. Analytical data, such as NMR and HPLC, often show tight peaks, which means fewer artifacts cloud the analysis.
Application range continues to widen. Corey Lactone Diol has drawn attention as a monomer in specialty polymer synthesis. In lab settings, its lactone ring adds backbone rigidity, while the diol units allow more crosslinking points. That dual reactivity expands the toolbox for polyurethane and polyester chemists chasing stronger, more heat-resistant plastics. R&D teams report that these polymers can withstand repeated heating and mechanical stress without breaking down as fast.
In coatings, the material works much the same way. Its structure supports film formation without making the end product brittle. I’ve spoken with formulators who say blends including Corey Lactone Diol flow better during application and form layers that hold up under abrasion. Sometimes, these coatings also resist yellowing longer than alternatives made with simpler diols. Adhesive manufacturers looking to balance flexibility and strength have also gravitated toward Corey Lactone Diol. It brings a good mix of polar and non-polar characters, encouraging strong bonds to challenging surfaces.
Another application I’ve seen discussed is in specialty surfactants. The two hydroxyl groups on the diol enhance water solubility, while the lactone ring brings stability to the final molecule. In detergents or dispersants designed for difficult tasks, even a small percentage of Corey Lactone Diol in the mix shifts performance by softening hard water effects and helping with emulsification. Early reports from pilot-scale detergent synthesis suggest the compound also helps reduce residue without causing foaming problems—practical improvements above textbook results.
Plenty of choices crowd the chemical market. Ethylene glycol and 1,4-butanediol have served industry for decades. Yet their linear structures can fall short for next-generation materials. Corey Lactone Diol’s ring system changes reactivity and opens the door to different reaction pathways. This feature shows up in practice. Where standard glycols make flexible chains but lack toughness, the rigid segment in the lactone diol brings balance—more mechanical strength, fewer compromises.
The real distinction isn’t just in physical properties. Synthesis steps benefit too. Because the two hydroxyl groups differ subtly in reactivity, seasoned chemists can guide selectivity in downstream transformations. For example, a friend of mine pointed out that in ester synthesis, Corey Lactone Diol reacts more predictably with acylating agents under mild conditions. That avoids overreaction and reduces purification work, which always becomes a bottleneck. The time saved in these steps adds up, especially at scale.
Compared to other cyclic diols, the lactone ring in Corey Lactone Diol isn’t just another moiety. The ring resists attack from common bases and acids better than some alternatives—important in processes where pH swings or environmental factors challenge raw materials. Companies focusing on specialty plastics with strict regulatory demands see dependable shelf-life and fewer complaints about degraded batches. From what I’ve seen, switching to this compound cuts down on returns and boosts customer trust.
Safety keeps its place at the front of any process involving new organics. Corey Lactone Diol generally shows low acute toxicity, though usual precautions—gloves, eye protection, fume hood procedures—still hold. Its relatively high melting point means accidental spills solidify fast and can be scraped up, rather than spreading. In biodegradability tests, the lactone ring often attracts interest from those looking to reduce environmental persistence. Limited data so far suggests spent material breaks down faster than aromatic-based diols, easing pressure from regulatory bodies.
From an occupational exposure viewpoint, the crystalline form reduces dust generation compared to powder-based glycols, lowering risk of inhalation. Handling residues tend to appear more in storage containers than in the air. This small but real benefit matters in busy R&D settings or high-throughput packaging stations, where repeated exposure builds over time.
Back in the early days of adoption, skepticism ran high. One major plant manager doubted that a novel diol could bring down defect rates in plastic sheet production. After a series of runs, engineers noticed smoother melt flow, lower torque loads on the extruder, and more even cooling throughout the sheet. Yield loss at the edges, a stubborn problem for years, dropped by ten percent—enough to pay for the switch inside a single quarter. QC teams traced the improvement back to the core physical properties of Corey Lactone Diol, especially its unique ring structure and consistent functional group placement.
In another example, a mid-sized adhesives shop swapped out a more reactive diol for this material, tuning run conditions for slightly slower curing. The shift led to products with higher peel strength and less warping on flexible substrates. Tech staff reported fewer returns from construction customers, especially on temperature swings that used to split the bond after a hard freeze. The lab supervisor told me that process stability matters as much as raw performance—in their case, Corey Lactone Diol delivered both in the long run.
Sustainability questions rise as industries confront new rules and consumer pressure. Biodegradable, non-aromatic polyesters made with Corey Lactone Diol draw less suspicion in regulatory inspections. Even if the supply chain still relies on fossil starting points, each move away from persistent aromatics matters, especially for packaging or disposable medical goods. Meanwhile, recyclers launching new take-back programs often ask for polymer supply data. Polymers based on the lactone diol have drawn more positive feedback than standard formulations.
Nobody pretends this solves all sustainability concerns. But the chance to adjust molecular design—combining rigidity, processability, and improved environmental fate—matters to buyers and engineers alike. Brands touting compostable or low-impact plastics use this as a credibility win. Reports from early adopters point to higher sales in green product lines, which encourages continued R&D investment.
Most compounds look good in grams or kilograms. Only some put on a strong showing in tons. Corey Lactone Diol has shown a smoother path from bench work to plant scale, mostly because of predictable crystallization and cleaner melt behavior. At the same time, pressure stays on suppliers to deliver consistent lots every time. As scale grows, subtle tweaks—cleaner reactors, tighter temperature control, careful drying—make the difference between a winning batch and a rework.
Process engineers I’ve met describe how small impurities in raw feedstocks can still throw a wrench into multi-ton runs. Using Corey Lactone Diol with a known impurity profile limits those surprises. Automated dosing and continuous feedback loops keep process variables on target, and in turn, finished polymers match specifications without costly adjustments. Line managers feel real relief handing down fewer batch rework orders and seeing higher “first pass” success rates.
It is one thing to tout benefits on paper. Day-to-day results set Corey Lactone Diol apart, reflected in feedback from operators and end users. Molded parts using this diol show fewer stress cracks, especially after accelerated weathering tests. Finished coatings resist fingerprints, water spots, and UV fading longer than those made from more linear diols. One automotive supplier mentioned fewer customer complaints on dashboard trims faded by sun exposure—an expense saved both in warranty costs and brand image.
Reliability takes real effort. Chemists working with the product value precise melt profiles during processing. Polymer viscosity stays in a sweet spot—neither so high it clogs the extruder, nor so low it runs off before setting. Operators spend less time chasing furnace temperatures, and more hours pulling uniform product runs. Maintenance crews have noticed less buildup on plant lines, a small perk but one felt during tight production schedules.
Few advances spread without technical support. Early Corey Lactone Diol adopters shared data through professional networks. Industry conferences became settings for swapping details—how to tune reactivity, which co-monomers blend best, where process choke points hide. Engineers new to the compound often lean on these informal channels, seeking advice on melting points, drying cycles, and QA hurdles.
Community-driven documentation helps. Sharing “what went wrong” stories goes as far as celebrating best practices. Those firsthand reports shorten the learning curve for others making the switch. Technical bulletins from suppliers fill in some gaps, but nothing replaces experience earned one batch at a time. Even experienced hands admit that new diols force adjustments in old routines—patience and curiosity pay off.
Those hydroxyl groups, both primary and secondary, invite selective transformations. Multi-step synthesis often depends on fine control of reactivity. In practice, Corey Lactone Diol enables different protection and deprotection strategies, opening the way for building block diversification. Medicinal chemists and polymer experts alike have taken note.
Across R&D teams, this means fewer steps wasted on defensive chemistry. Fewer unwanted side products show up, and resources stretch farther. Labs running high-throughput screening turn out more hits per week. Cost savings come less from raw material price than from fewer hours debugging unwelcome surprises. In an age where technical teams run lean, these improvements really make a mark.
With every shift in market demand or regulatory climate, building block selection grows more critical. Corey Lactone Diol, with its blend of rigidity, flexibility, and functionality, stands out as a strong candidate for a range of specialty goods. Polymer makers rely on consistent supply chains and the assurance of predictable properties. R&D leaders look for ways to hit both performance and environmental targets without prohibitive cost or complexity.
Corey Lactone Diol pushes this quest forward—not through marketing hype, but thanks to results proven on the shop floor and in the field. Product lines built around the compound tend to earn lasting reputations. From heat-stable medical devices and scratch-resistant consumer goods, to eco-friendly coatings that please both clients and regulators, a simple shift in starting material has real-world impact.
Innovation journeys rarely move in a straight line. Early users took on risks, learned from setbacks, and reshaped technical roadmaps. New entrants tap into richer pools of collective wisdom. Regular exchanges, bench tests, and production-scale trials drive steady improvement. Each success with Corey Lactone Diol raises the standards for what specialty diols must deliver next.
The pace of technical progress keeps accelerating. As the community around this compound grows, its influence pulls other innovations along with it. Competitors will keep pushing, but reliability, versatility, and practical performance set the new benchmark. Corey Lactone Diol, once an outsider, steps confidently into the toolbox of mainstream chemical and manufacturing industries, ready to meet the demands of tomorrow’s marketplace.