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All Right Reserved
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HS Code |
284082 |
| Name | Acetylacetone |
| Iupac Name | Pentane-2,4-dione |
| Cas Number | 123-54-6 |
| Molecular Formula | C5H8O2 |
| Molar Mass | 100.12 g/mol |
| Appearance | Colorless liquid |
| Melting Point | -23 °C |
| Boiling Point | 140-142 °C |
| Density | 0.975 g/cm³ |
| Solubility In Water | Slightly soluble |
| Vapor Pressure | 2.7 kPa (at 20 °C) |
| Flash Point | 35 °C (closed cup) |
| Odor | Pleasant, fruity |
As an accredited Acetylacetone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Acetylacetone, 500 mL, is packaged in a brown glass bottle with a secure cap, featuring hazard labels and product details. |
| Shipping | Acetylacetone should be shipped in tightly sealed containers, away from heat, sparks, and open flames, as it is flammable. Ensure it is clearly labeled and protected from physical damage. Transport in compliance with local, national, and international regulations, typically under UN number 2310, in a well-ventilated and cool environment. |
| Storage | Acetylacetone should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep it separate from oxidizing agents, acids, and bases. Use proper chemical storage cabinets, and avoid temperature extremes to prevent decomposition. Always ensure containers are clearly labeled and check for leaks regularly to maintain safety. |
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Purity 99%: Acetylacetone Purity 99% is used in metal chelation processes, where it enhances selectivity and efficiency in forming stable metal complexes. Molecular Weight 100.12 g/mol: Acetylacetone Molecular Weight 100.12 g/mol is used in catalyst synthesis, where it ensures precise stoichiometric reactions for reproducible catalytic properties. Boiling Point 140°C: Acetylacetone Boiling Point 140°C is used in solvent extraction applications, where it enables effective separation of transition metals. Water Solubility 13 g/L: Acetylacetone Water Solubility 13 g/L is used in aqueous phase chemical synthesis, where it provides improved homogeneity resulting in higher yield of target compounds. Stability Temperature Up to 200°C: Acetylacetone Stability Temperature Up to 200°C is used in polymerization catalyst systems, where it maintains performance without thermal degradation. Viscosity 0.8 mPa·s: Acetylacetone Viscosity 0.8 mPa·s is used in thin film deposition processes, where it enhances uniform coating formation due to optimal fluidity. Acidity (pKa 8.9): Acetylacetone pKa 8.9 is used in pharmaceutical intermediate synthesis, where it facilitates controlled enolate formation for selective reaction pathways. UV Absorbance (λmax 270 nm): Acetylacetone λmax 270 nm is used in analytical chemistry as a chromogenic reagent, where it provides sensitive spectrophotometric detection of metal ions. Density 0.975 g/cm³: Acetylacetone Density 0.975 g/cm³ is used in formulation of specialty inks, where it contributes to stable dispersion and optimal print quality. Melting Point -23°C: Acetylacetone Melting Point -23°C is used in low-temperature chemical synthesis, where it remains in liquid phase to ensure continuous reaction flow. |
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Acetylacetone, also known as 2,4-pentanedione, shows up in labs and factories far more often than most people realize. Its transparent, colorless liquid form gives away little about the lively chemistry inside each molecule. As someone who spent early days cleaning glassware in a university lab, I've witnessed just how wide-reaching a role this compound plays. I remember the whiff of its distinct aroma and the precision required in measuring it, always mindful of its volatility and potential to stain benches if spilled.
Acetylacetone comes with the formula C5H8O2 and a molecular weight hovering just under 100. That means each bottle packs quite a punch for its size. Unlike dry, dusty powders or chunky salts, acetylacetone pours like water and smells faintly sweet, almost like overripe fruit. This specific aroma lingers for a reason: its molecules dance between two structural forms in what’s called keto-enol tautomerism. Anyone who’s peered into a flask after adding it to a reaction has seen firsthand how quickly it can dissolve into a solution or shift its structure in response to changes in temperature or pH.
Chemists count on acetylacetone as a trusted ligand — a molecule that latches onto metals and creates stable complexes. My graduate advisor always seemed pleased when an experiment required acetylacetone; it brings a kind of predictability into the otherwise uncertain world of metal ion chemistry. From my practical experience synthesizing nickel and copper chelates, I learned that the resulting compounds not only display striking colors but also become easier to handle and purify thanks to the stability acetylacetone lends. Researchers in industries ranging from fuel additives to pharmaceutical synthesis rely on it to shape reactions or extract metals out of solutions.
Some chemicals show up quietly at the edges of everyday products, rarely given a second thought outside specialist circles. Acetylacetone plays that kind of silent but essential role. Take the coatings and paints industry, for example. This compound modifies viscosity, controls drying times, and boosts pigment dispersion. Those benefits show up in ways most people never notice unless the paint fails to cover evenly or flakes prematurely. In agriculture, manufacturers use acetylacetone in the process of making fungicides. Many common garden products wouldn’t work as well without its contribution to the chemical backbone of the ingredients inside.
It’s easy to mistake acetylacetone for its cousins: other beta-diketones like benzoylacetone or hexafluoroacetylacetone. Each of these siblings comes equipped with a similar “handle” for clasping metals, but acetylacetone stands out for its affordability and straightforward handling. Some alternatives cling to metals more tightly or withstand higher temperatures, but acetylacetone often balances cost, reactivity, and environmental footprint better than the rest. In my experience, purchasing teams always lean toward acetylacetone when balancing budgets, and lab managers appreciate its predictability compared to more exotic options. Environmental safety regulations recommend choosing chemicals with manageable risks and simple disposal — something acetylacetone offers better than fluorinated relatives known for environmental persistence.
A bottle labeled as pure acetylacetone usually delivers at least 99 percent purity, and that figure matters to anyone chasing reliable results in research or manufacturing. Even tiny impurities throw off reaction yields or introduce variables in quality control. During quality assurance routines at my previous job, analysts tracked purity down to the third decimal place using gas chromatography. Consistency reduces surprises and saves time on troubleshooting downstream. Boiling point lands near 140°C, flashing point close to 34°C, and specific gravity keeps it slightly denser than pure water. That information might sound dry, but in the hands of an extractor or a chemical technician, these numbers guide every safe transfer, mixing, and storage decision. No one wants a runaway reaction or an unnecessary spill.
Anyone storing acetylacetone in the workplace appreciates its straightforward storage: a cool, well-ventilated place far away from flames. Its low flash point means it evaporates easily and catches fire more quickly than many other lab reagents. The first time I cracked open a fresh bottle, the pungency reminded me to respect its volatility. Goggles, gloves, and lab coats become routine with regular handling, not just paperwork compliance. Accidental contact can cause headaches or mild irritation, but I’ve also seen coworkers recover quickly by washing up within seconds of exposure. Fume hoods, good training, and proper labeling take care of most risks.
Analytical chemists rely on acetylacetone for its knack at highlighting specific metal ions in complex samples. In trace analysis, forming stable colored complexes with metals such as aluminum or iron is often crucial. Students in my analytical chemistry course quickly picked up on the simplicity acetylacetone brought to sample preparation: a sharp color change signals the formation of a new complex, making detection all the more straightforward. In industrial water testing, this rapid, low-cost method has made regular compliance work smoother and more reliable.
The value of acetylacetone in organic synthesis appears in countless academic publications and patents. It acts as more than just a bench reagent; it opens the door to a whole class of synthetic strategies. I once participated in a project developing new pharmaceuticals, where acetylacetone played an integral role in constructing heterocyclic compounds. Because it readily undergoes condensation reactions, it bridges building blocks into larger, biologically active structures with impressive efficiency. Its ability to tautomerize underpins its versatility, offering chemists a two-in-one tool for both nucleophilic and electrophilic reactions.
Chemists often shortlist other diketones or ligands while planning metal extraction or catalysis. Past projects of mine have substituted hexafluoroacetylacetone for acetylacetone when seeking more volatile complexes or deeper chelation strength. The drawback with these heavier cousins always circles back to cost, toxicity, and disposal headaches. Acetylacetone keeps operations lean because it’s easy to store and doesn’t introduce perfluorinated byproducts. Solubility differences also come into play. Acetylacetone dissolves in most polar and nonpolar solvents alike, making it a better fit for routine extractions, while more specialized chemicals tend toward niche applications.
No chemical arrives without a footprint. Conversations with environmental managers at my previous employer highlighted acetylacetone’s moderate toxicity and ease of biodegradation, a clear advantage over more stubborn synthetics. Of course, that’s only true when users collect and dispose of waste according to local guidelines. Frequent briefings on proper disposal prevented the kind of mishaps that make headlines or draw fines from regulators. Compared to strongly halogenated solvents, acetylacetone represents a step toward greener routine chemistry, especially in processes that demand frequent use.
The demand side paints a picture of steady, reliable growth, as coatings, adhesives, and polymers industries seek chemicals that deliver performance without spiking operation costs. Many procurement managers now evaluate sustainability as a key selection factor. With new regulations and ESG reporting requirements, acetylacetone scores higher than many alternatives, making it a recurring line item on procurement lists. During industry trade shows, booth representatives often cite increased interest in acetylacetone for solvent formulations and alkyd resin synthesis — sectors always on the lookout for alternatives to outdated, more hazardous solvents.
Laboratories around the world continue pushing acetylacetone into new scientific territory. Researchers from major universities and national labs routinely publish work on its potential in thin-film deposition, especially in electronics manufacturing. One memorable symposium session focused on atomic layer deposition, where the panel showcased acetylacetone’s controlled reactivity. Its mild behavior makes it ideal in creating even, defect-free layers for electronics, a far cry from its historical use strictly in analytical labs. During a stint assisting a postdoc, I observed firsthand how the choice of ligand affects film quality — acetylacetone often delivered better results with fewer unintended side reactions compared to bulkier candidates.
Global market analysis consistently points to stable supply and competitive pricing. Since its precursor chemicals stem from established petrochemical processes, acetylacetone doesn’t fall prey to the kind of wild price swings that hit specialty reagents dependent on rare minerals or restricted imports. During the pandemic-related supply chain disruptions, we scrambled more for nitriles and amines, but acetylacetone shipments arrived on schedule. That reliability pared down downtime and made long-term planning less of a gamble.
Medical research and workplace health studies document mild irritant effects if mishandled but not the chronic toxicity seen with many aromatics or chlorinated solvents. In larger-scale settings, management teams invest in fresh air exchange and periodic air quality monitoring. At a former employer, annual checkups never flagged acetylacetone among top-risk exposures — a relief compared to the strict monitoring tied to benzene or toluene. While personal protective equipment always stays at the ready, the substance empowers safer innovation and daily workflow than much of the chemical competition.
Chemistry instructors appreciate acetylacetone for making abstract concepts tangible. Its clear phase transitions, vivid color complexes with metals, and easy handling encourage hands-on learning. During undergraduate lab sessions, students quickly identified chelation effects, IR spectra shifts, and organic reaction mechanisms by working with acetylacetone. Teachers leveraged its affordable price and low acute hazards to replace or supplement more hazardous compounds — a smart move for risk mitigation in education.
Not every acetylacetone application sails by without hurdles. Because of its tendency to evaporate and its sensitivity to strong bases, labs often improvise with cold storage or inert gas blankets. Automation engineers have tweaked syringe pumps and reactors to reduce emissions, while production chemists switch up batch sizes or container shapes to keep things process-friendly. Real-world experience shows most obstacles shrink with minor tweaks: rotating stock more quickly, reinforcing ventilation, or refining purification steps downstream.
Attention increasingly turns to sustainability in chemical production. Companies fine-tune synthetic pathways for acetylacetone, relying more on renewable feedstocks or improved catalytic cycles. Life cycle assessments often point out how switching to less energy-intensive distillation steps or reusing mother liquors trims both costs and environmental impact. Industry roundtables and sustainability audits in the chemical sector frequently highlight acetylacetone as a positive case compared to heavier, less degradable alternatives. Scientists continue to refine methodologies, hoping to further reduce waste and increase efficiency in its production lines.
The field still has a few sticking points. While acetylacetone solves countless technical problems, a handful of applications outgrow its capabilities, pushing users to invent newer, more specialized reagents. For work involving metals in especially harsh environments or with ultra-high purity demands, researchers turn to enhanced ligands or hybrid molecules. At the same time, health and safety professionals keep pressure on suppliers to improve packaging practices and build in spill-proof features. Storage remains a weak spot in many facilities due to its volatility, calling for improved guidance on stock rotation and labeling.
Practical solutions start with ongoing employee training and investing in small environmental upgrades. Institutions can lower risk and boost compliance by standardizing on acetylacetone where performance checks out, while limiting use of more hazardous alternatives to only those applications that demand it. Waste stream audits and annual reviews keep facilities on top of disposal best practices, preventing costly surprises. Supply chain security improves when organizations keep secondary suppliers lined up, maintaining flexibility during sudden market shifts. Sharing case studies and lessons learned between labs and factories helps the wider field refine best practices year after year.
Industry and research both thrive on substances that balance effectiveness, manageability, and sustainability — qualities acetylacetone brings to the table time and time again. In the years working with this compound, it’s clear how its adaptability bridges generations of scientific progress. It powers classic analytical techniques while also contributing to today’s digital manufacturing and advanced materials development. As the chemical industry shifts toward greener, more transparent practices, acetylacetone stands out as a reliable, manageable, and thoroughly studied tool. Keeping an eye on safety, continuous education, and collaborative problem-solving ensures that this modest molecule remains central to smart, responsible chemistry for years to come.
