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4-Nitropyrene

    • Product Name 4-Nitropyrene
    • Alias 1-Nitropyrene
    • Einecs 221-880-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    890656

    ChemicalName 4-Nitropyrene
    CASNumber 6308-04-9
    MolecularFormula C16H9NO2
    MolecularWeight 247.25 g/mol
    Appearance Yellow crystalline powder
    MeltingPoint 238-240 °C
    Solubility Insoluble in water; soluble in organic solvents
    Density 1.45 g/cm³
    PubChemCID 123825
    SMILES C1=CC2=C3C=CC=CC3=CC4=CC=CC(=C4C2=C1)[N+](=O)[O-]
    InChI InChI=1S/C16H9NO2/c18-17(19)15-8-6-10-4-2-1-3-9(10)7-11-12-5-13-14(16(11)15)12/h1-8H
    Synonyms 1-Nitropyrene, 4-Nitro-1H-pyrene

    As an accredited 4-Nitropyrene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 4-Nitropyrene (10 grams) features a sealed amber glass bottle with hazard labels, stored in a protective cardboard box.
    Shipping 4-Nitropyrene should be shipped in compliance with hazardous materials regulations. It must be packed in secure, properly labeled containers, protected from light and moisture. Transport must be conducted by authorized carriers, and accompanied by safety data sheets. Appropriate personal protective equipment (PPE) and emergency procedures should be available during handling and transport.
    Storage 4-Nitropyrene should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from heat, light, and sources of ignition. Keep separate from incompatible substances, such as strong oxidizers and reducing agents. Clearly label the container and ensure storage in compliance with safety regulations. Use appropriate secondary containment to prevent accidental release or contamination.
    Application of 4-Nitropyrene

    Applications of 4-Nitropyrene in Industrial Manufacturing

    As a specialized manufacturer of 4-nitropyrene, we focus on supplying this polycyclic aromatic compound to high-value industrial sectors where its molecular structure and nitro functionality provide differentiated benefits. We align our production, QC systems, and technical services to meet the stringent demands of each real application area. Below we present our key downstream deployment scenarios, including compliance, integration methodology, and typical product types found in professional industrial environments.

    1. Organic Semiconductors for Electronic Device Development

    In the field of organic electronics, manufacturers utilize 4-nitropyrene as a building block for high-performance organic semiconducting polymers and small molecules. Its electron-withdrawing nitro group and extended aromatic core enable tuned molecular orbitals and charge transport properties, crucial for device stability and efficiency. The integration process is tightly controlled to ensure purity and batch consistency, as electronic-grade specifications demand precise synthesis and minimal impurity levels.

    Industry compliance standards

    • IEC 62899-201 International Electrotechnical Standard for Printed Electronics
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)
    • JIS C 61290 (Japanese Industrial Standards for organic and molecular electronic materials)
    • ISO 9001:2015 (Quality Management System for electronics manufacturing)

    Typical usage ratio

    • 0.5% - 3% by weight in polymer precursor formulations; dosage varies based on targeted charge carrier mobility and film morphology.

    Downstream process integration

    • Precursor mixing for solution-processable semiconductors
    • Incorporation during step-growth or chain-growth polymerization in pilot-scale reactors
    • Thin-film deposition (spin coating or inkjet printing) after formulation and cross-linking
    • Post-synthesis functional group modification, if customized derivatives are needed

    Final product types

    • Organic field-effect transistor (OFET) arrays
    • OLED (organic light-emitting diode) and OPV (organic photovoltaic) devices
    • Flexible display substrates
    • Sensors for environmental and medical monitoring

    2. Specialty Dye Synthesis for Fluorescent Probes

    The molecular backbone and conjugation system of this raw material serve as a platform for creating specialized fluorescent dyes used in advanced analytical and bioimaging sectors. Fine chemical producers modify the nitro functionality to introduce distinct absorption and emission profiles. The synthetic route requires careful control to prevent over-reduction or unwanted side reactions, ensuring spectral reproducibility in final probe applications.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for synthetic intermediates and end-use dyes
    • IUPAC Nomenclature and Labeling for colorants
    • ISO 1833 for quantification/purity of organic dyestuffs
    • GLP (Good Laboratory Practice) for analytical reagent manufacturing

    Typical usage ratio

    • 2% - 6% molar ratio in dye precursor blends; fine-tuned according to desired quantum yield and compatibility with target biomolecule labeling protocols.

    Downstream process integration

    • Nitration or post-nitration functionalization in batch reactors
    • Condensation with amines for fluorophore extension
    • Chromatographic purification followed by detailed spectral QC (HPLC, NMR)
    • Packaging under inert atmosphere for preservation of fluorescence intensity

    Final product types

    • Single-molecule fluorescent probes for confocal microscopy
    • Labeling reagents for flow cytometry
    • Visible/NIR fluorescent standards for instrument calibration
    • Chromatographic markers in biochemical assay kits

    3. Reference Standards and Analytical Controls for Environmental Monitoring

    Environmental laboratories and reference standard suppliers employ 4-nitropyrene as a trace-level analytical control in PAH (polycyclic aromatic hydrocarbon) monitoring projects. Its known toxicological and persistence profiles make it a relevant standard for soil, water, and air quality assessment. The material is routinely manufactured under strict purities above 98% and supplied with accompanying certificates to facilitate accurate quantification by downstream laboratories using mass spectrometry or GC/MS methods.

    Industry compliance standards

    • US EPA Method 8270D (Semivolatile Organic Compounds by GC/MS)
    • EN 16619 (European standard for PAH determination in environmental samples)
    • ISO/IEC 17025:2017 (Testing and calibration laboratories)
    • ASTM D4762 (Standard Test Method for PAH in industrial materials)

    Typical usage ratio

    • 1–10 ppm in certified reference material solutions for spiking and calibration; concentrations set according to analytical instrument sensitivity and target matrix complexity.

    Downstream process integration

    • Weighing and dissolution into methanol/acetonitrile by automated dispensers
    • Sealed in ampules or vials with inert gas headspace to prevent photodegradation
    • Quality batch validation using LC-MS or GC-MS against NIST reference standards
    • Traceable shipping for guaranteed cold-chain and anti-contamination protocols

    Final product types

    • Certified reference standard solutions for calibration curves
    • Spiking standards for recovery studies in environmental labs
    • Matrix-matched controls for soil, sediment, and biological fluids
    • Quality assurance samples for government and industrial monitoring programs

    4. High-Temperature Resistant Pigment Precursors for Engineering Plastics

    Polymer compounders and masterbatch manufacturers leverage the thermal stability and chromophoric nature of this molecule for synthesizing pigment intermediates that deliver resistance to degradation in engineering thermoplastics. The nitro functionality offers a reactive handle, while the extended π-conjugation contributes to heat- and lightfast shades required for demanding applications such as wire insulation, automotive interiors, and aerospace resin systems.

    Industry compliance standards

    • UL 94 (Flammability ratings for plastic materials)
    • ANSI/ASTM D4963 (Color and optical properties in plasticizers)
    • ISO 14021 (Environmental labeling for polymer additives)
    • RoHS Directive (EU) 2015/863 ([Pb], [Cd], [Hg], and other substance restrictions for plastic products)

    Typical usage ratio

    • 0.2% – 1.5% by weight in pigment synthesis batches; dosage depends on target L*a*b* color space and matrix compatibility in final polymer systems.

    Downstream process integration

    • Direct nitration or post-nitration coupling within colorant precursor synthesis
    • Blending with plasticizer or polymerizable monomers for dispersion stability
    • Extrusion into masterbatches or pellet forms before compounding
    • Thermal processing QC to verify pigment migration, yield, and chromatic integrity at >180°C

    Final product types

    • High-temperature stable color masterbatches for polycarbonate (PC), PEEK, and PPS
    • Engineering resin-based molded components with specific heat and UV resistance
    • Automotive and aerospace interior panels with long-term chromatic durability
    • Wire and cable insulation granules for electrical and electronics grade applications

    5. Structural Intermediate for Advanced Material Research and Development

    In academic and industrial R&D laboratories, chemists employ 4-nitropyrene as a strategic intermediate for the derivatization of new molecular architectures. Its structural attributes enable the study of substitution effects, π-π stacking, and optoelectronic behavior across advanced material classes. Synthesis and subsequent manipulation are performed in controlled lab-to-pilot transitions with traceability and regulatory reporting, especially where scale-up or patent applications are anticipated.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice (GLP)
    • REACH Annex VII for research intermediates
    • ISO 17034:2016 (Reference material producers)
    • In-house technical specification protocols under ISO 9001

    Typical usage ratio

    • 0.1–10 mmol per batch; amount adjusted on reaction stoichiometry and the scale (mg to gram-quantities) used in pilot experiments and discovery chemistry workflows.

    Downstream process integration

    • Initial functionalization or cross-coupling as a core building block in combinatorial chemistry
    • Assignment as a standard substrate in kinetic or mechanistic studies
    • Resin or bead attachment for library synthesis via solid-phase methods
    • Designated recycling and waste handling according to laboratory chemical management programs

    Final product types

    • NOVEL π-conjugated molecules and polymers for academic publication
    • Material test panels for physical and surface property evaluation
    • Experimental benchmarks in high-throughput screening systems
    • Prototype specialty chemicals, pending further pilot or commercial validation
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    Certification & Compliance
    More Introduction

    4-Nitropyrene: Insights from a Chemical Manufacturer

    Stability and Consistency at the Core

    In our daily work at the plant, 4-Nitropyrene (Chemical Formula: C16H9NO2) emerges as one of those specialized compounds that consistently draws attention for its robust ring structure and unique nitro functional group. The compound presents itself as yellow crystalline solids, which makes it easy to distinguish from other polycyclic aromatic hydrocarbons lying on the same lab bench. All production batches pass through vigilant QA testing, underscoring that consistency is the top priority. We monitor melting points to ensure tight compliance with published standards, and impurities get flagged quickly. You know the production run went right when the dry, yellow powder pours free of clumps and the lights in the quality lab reveal nothing but clear, gold hues without tints or streaking.

    Our entire team is acutely aware that researchers count on this kind of consistency. Nobody in analytical chemistry or synthetic development wants to waste days sorting out whether unexpected results come from a rogue impurity. We stick to proven purification methods developed over dozens of pilot batches, so each drum has predictable qualities: purity levels going well above 98%. The model stays the same each time because lab results demand repeatability. When chemists downstream handle our 4-Nitropyrene, they trust that they can replicate their tests and experiments without back-tracking through raw materials as a source of error.

    Purpose and Industry Use Cases

    There’s no hiding from hard realities in industry: 4-Nitropyrene doesn’t belong in mass-market plastics or every epoxy found in household hardware stores. We encounter its real value at the intersection where industrial research meets environmental studies and specialized chemical synthesis. The product shines as a standard or reference in environmental analysis—especially when tracking polycyclic aromatic hydrocarbon contamination. Regulatory agencies and academic labs use minute amounts to calibrate detectors for trace analysis. Without high-quality 4-Nitropyrene, environmental chemists would struggle to set reliable baselines for soil and air monitoring. Here, accuracy comes before all else, and our staff has learned that sloppiness helps no one.

    The material also plays a role as a substrate for scientific studies on mutagenicity and carcinogenicity. 4-Nitropyrene’s structure stands as an archetype among nitro-PAHs (polycyclic aromatic hydrocarbons), so researchers digging into environmental toxicology use it to map metabolic pathways or track by-products of combustion in laboratory animals. They come back looking for the same supplies, in the same form, with zero tolerance for cross-contamination or degradation.

    Our technical department has talked with buyers from academic labs setting up intricate cell culture toxicology experiments. They require sharp reproducibility for control groups—something that only comes from batch-tested, traceable lots. Working with a supplier tied directly to the production process, rather than a chain of resellers, offers researchers peace of mind. We keep our records open for audit and trace every step from raw feedstocks, through nitration, to crystallization and packing. As producers, it's our responsibility to maintain this chain of trust intact at every handoff.

    Precision Manufacturing: Beyond Simple Purity Metrics

    Years in nitroarene synthesis taught us that chasing purity alone, without understanding the subtle chemistry, risks bottlenecks on the shop floor. 4-Nitropyrene likes to play tricks during final filtration, with color changes suggesting traces of isomers or breakdown products. Rather than rush, our crew developed careful protocols for solvent choice and filter selection—proven through repeated runs. It’s experience earned through trial and error: we know a certain solvent blend draws off the last hints of process byproducts more thoroughly. Process improvement doesn’t stop once product clears the characterization lab. It’s the heartbeat of practical manufacturing.

    The material jumps out in fluorescence detection under UV light, so each QA cycle involves visual as well as spectral confirmation. If an ingredient batch used in synthesis doesn’t meet specification, its impact echoes through everything downstream. Most casual buyers remain unaware of this scrutiny, but research professionals come to value the documentation and hands-on insight available by working directly with the team responsible for every step of the process.

    Comparisons with Related Compounds

    In the chain of nitro-substituted polycyclic hydrocarbons, differences matter more than buyers expect. 4-Nitropyrene separates itself from analogues like 1-nitropyrene by the location of its nitro group, which determines reactivity and how the compound behaves in analytical testing. The metabolic fate of 4-Nitropyrene diverges sharply from its isomer, so toxicologists and environmental scientists can’t just swap them out. In our lab we run chromatographic separations that drive this point home. Isomers may appear similar, but after a few minutes the retention time tells another story. These distinctions become essential for published studies, risk assessments, and forensic investigations.

    4-Nitropyrene further sets itself apart from other multi-ring naphthalenes and anthracene derivatives, by showing a predictable response in the Ames test and clear, well-studied markers in metabolic profiling. Those looking only at the shared skeleton might overlook why experienced researchers sidestep cheaper, less characterized materials in favor of a carefully prepared, well-documented product. That’s not a matter of branding, but of evidence-backed reliability in critical applications.

    Integrity in Documentation and Support

    For every kilogram or vial shipped, our plant attaches complete analytical reports and certificates of analysis. Over the years, more than a few customers arrived at our facility looking to trace the journey of a specific lot—from feeding tank, through reactor, all the way to drum or sample bottle. This openness only comes from direct control of the production infrastructure. Relying on intermediaries tends to fog the trail and dulls accountability when questions arise regarding performance or quality in final use. Our staff absorbs all lessons from daily operations, feeding them back into improved SOPs, more sensitive analytical techniques, and tighter process control.

    Regulatory and safety expectations keep rising, and direct engagement with auditors remains part of life. No shortcuts provide coverage if someone misses a new impurity threshold or fails to adapt to a stricter customer requirement. As a producer, taking responsibility for every step builds genuine E-E-A-T (Experience, Expertise, Authority, and Trustworthiness), not just as a slogan but as a daily expectation. Chemists using 4-Nitropyrene in health-related studies understand the human significance behind error-free manufacturing. Our company’s engineers stay ready to answer detailed questions about stability, shelf-life, or storage—supporting users at every stage instead of cutting corners after the sale.

    Handling and Storage Based on Firsthand Observation

    Staff on the floor will tell you—right down to the warehouse clerks and lab technicians—that dry, cool, and stable conditions matter. 4-Nitropyrene keeps best sealed from moisture and away from open light, as we learned from the handful of past incidents where open samples drew condensation during summer humidity spikes. We replaced storage bins with desiccant-packed, light-proof containers after finding even trace dampness dulled the sharpness of yellow crystals. No one wants gradual oxidation or photolytic break-down, especially given the sensitivity of reference standards. If researchers need assurance about shelf-life or recovery after storage, our direct records explain what worked in real-world plant conditions, not just what looks fine on paper.

    Our logistics staff remains proactive about labeling, secondary containment, and shipment to academic or commercial labs. We print handling advice based on chemical plant lessons: nobody learns more from a tipped drum incident than a crew who has to salvage it with their own hands. Clients counting on genuine samples—sometimes for legal proceedings—don’t have the option of a mistake. It’s on all of us at the plant to build procedures that keep quality high from reactor, through packaging, and until the product reaches the experiment or calibration bench.

    Real Experiences with Client Demands

    In practice, users seeking 4-Nitropyrene push us constantly for hard data and transparent documentation. We get requests for characterization by GC-MS, HPLC, and NMR—sometimes all three, depending on the destination country’s rules or publication requirements. It’s not enough to provide a basic melting point or single purity report. Often, university labs need reference chromatograms and spectra to compare side-by-side with their own calibration runs. Analysts expect the same data for each fresh lot, requiring us to commit to daily calibration of our own in-house instruments and keep records available for years.

    The customer feedback loop shapes each step. If a lot falls out of spec, every member of the production team takes part in root cause analysis. Retrospective testing on raw material lots, review of solvent choices, and re-examination of synthesis logs teaches better process control. No process update happens in isolation from practical lab realities. This ongoing dialogue with researchers, QA managers, and regulatory compliance officers is how we fine-tune the process and ensure users never get left with a product that only looks good on spec sheets without working as promised. This two-way flow of communication builds real trust—far more than advertising ever could.

    Supply, Batch Control, and the Problem of Counterfeits

    In specialized chemicals, counterfeit or sharply adulterated products exist. End users sometimes relay stories of failed toxicology trials and inconsistent peak patterns caused by substituted or mislabelled material. Years ago, we handled a case where a research group tried 4-Nitropyrene from an unknown global trader, only to find misassigned spectra and inconsistent melting point data. The consequences for the study involved lost months and compromised results. In response, we doubled down on batch traceability. Each container links to a master log for raw materia, synthesis, purification, and storage. Chemists with questions find answers straight from our production notebooks, not through indirect email chains circulating around the globe.

    Keeping the supply line direct also limits the chance for contamination in transit. Pallets leaving our plant go through secondary sealing, photographic logging, and real-time tracking for time-sensitive academic projects and regulatory submissions. In the end, our production team realized that staying close to the raw chemistry offers more control—and in scientific research, control is everything. Researchers can verify the chain-of-custody right back to our facility, giving them more confidence in publishing findings or presenting results to peer review boards.

    Pathways for Improvement and Problem-Solving

    The market for specialty PAHs such as 4-Nitropyrene rarely stands still. New testing protocols—especially for environmental and biological labs—push for even lower impurity levels and greater documentation granularity. In some cases, national health agencies update the threshold for known or suspected co-contaminants. We map all regulatory changes to internal process reviews, and put resources behind ambient air monitoring, trace solvent testing, and tighter personnel training. With feedback on evolving customer needs, we have invested in equipment upgrades and bespoke analytics.

    Solving process challenges involves everyone in the loop. Operators, QA chemists, and even packing personnel submit practical ideas, from delivering custom vial sizes for calibration labs to tightening grading criteria for downstream testing. These improvements arise from daily experience—solving bottlenecks as they show up, tracking customer complaints, and holding regular plant-wide reviews. The value of direct manufacturer experience comes in these small but critical practical insights that experienced users notice instantly.

    Looking Ahead in Chemical Manufacturing

    4-Nitropyrene stands out because it requires steady investment in manufacturing discipline, not simply more modern equipment or bigger batch capacity. We see the greatest demand among labs doing frontline research in toxicology, combustion pollutants, and regulatory analysis of PAHs in complex samples. The chemical’s importance will likely climb as global regulators track emerging environmental health risks. Meeting evolving requirements means we must keep improving lot integrity, enhancing technical support, and staying ahead of documentation expectations without letting productivity compromise core analytical values.

    It’s easy for outside marketers to repeat generalities about reliability and quality assurance. Our manufacturing team has learned to show real data, demonstrate open procedures, and stand behind batch records. Every drum and bottle carries our name because every person in production, testing, and distribution understands that even small lapses in quality or integrity can have major downstream consequences for scientific research and public health. That's what keeps quality at the front of every decision—from feedstock selection, through multistep synthesis, final crystallization, and careful, individually-inspected packaging for every order.

    Conclusion: Trust Built Through Work

    In the chemical business, trust doesn't reside in mission statements or on brochures. It’s earned one batch at a time. What sets genuine 4-Nitropyrene apart isn’t just analytical values and certificates—though both matter. The difference comes from a willingness to put hard-earned plant experience, transparent documentation, and open support behind the product, recognizing that our work touches real research, regulatory action, and public safety. Chemists, analysts, and regulators depend on producers who know every nuance of synthesis and storage. That responsibility stays front and center for the whole team here, and we treat it as a point of pride, not merely policy.