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HS Code |
224880 |
| Name | 4-Hydroxybenzoic Acid |
| Cas Number | 99-96-7 |
| Molecular Formula | C7H6O3 |
| Molecular Weight | 138.12 g/mol |
| Appearance | White crystalline powder |
| Melting Point | 213-217°C |
| Boiling Point | 277°C (decomposes) |
| Solubility In Water | 5.0 g/L (20°C) |
| Pka | 4.58 |
| Density | 1.47 g/cm3 |
| Odor | Odorless |
| Flash Point | 186°C |
| Storage Temperature | Room temperature |
| Ec Number | 202-804-9 |
| Synonyms | p-Hydroxybenzoic acid |
As an accredited 4-Hydroxybenzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4-Hydroxybenzoic Acid is supplied in a sealed, amber glass bottle with a tamper-evident cap and chemical hazard labeling. |
| Shipping | 4-Hydroxybenzoic Acid is shipped in tightly sealed, chemical-resistant containers to prevent contamination and moisture ingress. It is transported as a non-hazardous solid under ambient conditions, with clear labeling and documentation. Handling follows standard chemical safety protocols. Ensure compliance with local regulations during shipping and storage to maintain material integrity. |
| Storage | 4-Hydroxybenzoic acid should be stored in a tightly closed container in a cool, dry, and well-ventilated area. Keep it away from moisture, direct sunlight, and incompatible substances such as strong oxidizing agents. Store at room temperature and avoid excessive heat. Proper labeling and handling procedures should be followed to ensure safety and maintain chemical stability. |
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Purity 99%: 4-Hydroxybenzoic Acid with purity 99% is used in pharmaceutical syntheses, where it ensures optimal yield and high product safety. Melting Point 213°C: 4-Hydroxybenzoic Acid with a melting point of 213°C is utilized in high-temperature polymer production, where it provides thermal stability and processing efficiency. Particle Size <50 µm: 4-Hydroxybenzoic Acid with particle size less than 50 µm is used in cosmetic formulations, where it enables rapid dissolution and uniform texture. Moisture Content <0.5%: 4-Hydroxybenzoic Acid with moisture content below 0.5% is applied in preservative systems, where it enhances antimicrobial efficacy and product shelf life. Stability Temperature up to 200°C: 4-Hydroxybenzoic Acid with stability temperature up to 200°C is employed in adhesives manufacturing, where it maintains performance integrity under heat exposure. Molecular Weight 138.12 g/mol: 4-Hydroxybenzoic Acid with molecular weight 138.12 g/mol is used in dye intermediate production, where it supports precise reactant control and consistent color quality. |
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The chemical world offers a gallery of compounds, but few find themselves in as many corners of science and industry as 4-Hydroxybenzoic Acid. Known among chemists and manufacturers for its utility, this compound has worked its way into the heart of production lines, research laboratories, and even cosmetic factories. Though it carries a technical name, the molecule brings with it a practical range of uses that shape the quality and consistency of everyday products.
Most of us encounter the results of careful chemical preparation every day, whether we’re reaching for a bottle of lotion, taking a medication, or buying food that stays fresh far longer than it would naturally. Behind many of these products stands 4-Hydroxybenzoic Acid, sometimes referred to as a core building block for synthetic preservatives and specialty polymers. The wide reach of this compound is no accident. Scientists and engineers rely on its predictable structure and stable chemical profile to fine-tune qualities in finished goods. For years, I worked in a lab setting where consistency and predictability in our raw materials meant the difference between launching a product and sending it back to development. 4-Hydroxybenzoic Acid became a staple on our shelves not simply because it performed one job, but because it offered reliability across many roles.
Within laboratory and industrial circles, 4-Hydroxybenzoic Acid stands out for its purity and the reliability of its supply chain. The model most commonly discussed is the pure crystalline powder, free from contaminants and side products that often complicate large-scale operations. An effective product always starts with purity, ideally surpassing 99% as verified by high-performance liquid chromatography. This measure reduces the risk of introducing unwanted variables into formulations, which is vital for applications in pharmaceuticals, polymers, or food science.
Grain size and solubility factor into the usability of the acid. Consistent particle size allows researchers to measure, mix, and react the chemical with a greater degree of accuracy. Solubility in water and organic solvents opens the door for its inclusion in both water-based and solvent-based systems. During my time in formulation chemistry, I learned quickly how a discrepancy in particle size could cost hours or even days in lost development time. Fine, crystalline grades of 4-Hydroxybenzoic Acid lent our projects repeatable results, which made scaling up from the laboratory to production a realistic goal rather than a nerve-wracking gamble.
The most trusted sources offer material that meets or exceeds global standards, as reflected in widespread compliance with pharmacopeia and food-grade definitions. Manufacturers using 4-Hydroxybenzoic Acid in end products count on certificates of analysis, which document everything from melting points and residual solvents to heavy metal testing. This transparency has grown in importance, especially as global supply networks have widened and companies look to meet safety and quality requirements in every batch.
Long before most consumers would recognize the name, major pharmaceutical and personal care companies had built entire lines around derivatives of 4-Hydroxybenzoic Acid. One of its best-known transformations forms parabens, a family of preservatives famous for their ability to inhibit mold and bacteria in creams, lotions, and ointments. The effectiveness of these preservatives springs directly from the stability of 4-Hydroxybenzoic Acid, whose resistance to breakdown and oxidation gives finished goods a longer shelf life.
In the laboratory setting, 4-Hydroxybenzoic Acid works as a reference standard and as a raw material for synthesizing more complex compounds. It’s not simply a passive ingredient. Chemists shape and react its functional groups, taking advantage of its hydroxy and carboxylic acid moieties to create new molecules ranging from polymers to pharmaceutical intermediates. The versatility of this acid means a single purchase can supply multiple teams across research and manufacturing – a cost-saving move that has benefited operations both small and large.
I’ve witnessed firsthand how projects can stall or surge ahead depending on the quality of a key starting material. A run of poorly characterized or inconsistent 4-Hydroxybenzoic Acid meant procedure adjustments, quality retesting, and frustrated researchers. Reliable product kept our timelines and results on track. The peace of mind brought by a dependable supply chain is not to be underestimated.
Every batch of lotion, tablet, or packaged meat owes its safety and effectiveness not just to savvy formulation, but to the reliability of ingredients like 4-Hydroxybenzoic Acid. Companies need to know that their raw materials will meet tight tolerances on every delivery. If impurities creep in or the physical properties drift, the entire production process can be jeopardized.
Quality assurance teams lean heavily on documentation. Traceable batches, analytical data showing purity, and thorough hazard analysis all shape a company’s confidence in using such compounds. Traceability in the supply chain builds trust with downstream users, from pharmaceutical producers right on down to the end consumer. Trust, in my experience, anchors long-term business relationships and regulatory compliance.
4-Hydroxybenzoic Acid must hold up under scrutiny from both internal auditors and external regulatory agencies. At the bench, the lab, or the production line, employees want assurances that their tools work every time. As consumer awareness of ingredients grows, so too does the need for straightforward, reliable documentation and testing on the chemical’s pedigree. The transparency in its quality profile has earned it a respected place in so many sectors.
The chemical industry has no shortage of carboxylic acids or phenolic compounds, but few offer quite the balance seen in 4-Hydroxybenzoic Acid. Its dual functional groups lie at the intersection of reactivity and stability. While some analogues may decompose or lose activity during storage, 4-Hydroxybenzoic Acid maintains its chemical identity over long periods and under a range of conditions.
Some might point to benzoic acid or salicylic acid as alternatives, and it’s true they share certain characteristics. Still, neither fills the same spectrum of pharmaceutical and industrial needs. Salicylic acid plays a unique role in skincare as a keratolytic, but lacks the preservative power when transformed into esters like parabens. Benzoic acid offers preservative action, yet it doesn’t yield the same derivatives or possess the precise safety and allergenicity profile required in sensitive products.
In the world of specialty polymers, 4-Hydroxybenzoic Acid stands nearly alone in its role as a core monomer for producing liquid crystal polymers. Its rigid, planar structure becomes essential for achieving the unique physical and thermal properties needed for advanced electronic or automotive applications. Few other readily available compounds supply both the stability and the reactivity needed to build these technical materials.
Each new demand placed on the material – tighter purity, more reliable sourcing, greater ecological safety – prompts suppliers to improve their preparation methods. It’s not unusual to see big advances in purification and sustainable production, all aimed at keeping 4-Hydroxybenzoic Acid relevant and increasingly environmentally compatible in a changing global climate.
In the controlled chaos of daily laboratory work, not every ingredient can claim to streamline a process rather than introduce headaches. 4-Hydroxybenzoic Acid proved its worth by fitting smoothly into automated systems. Dosing machines, quality control instruments, and mixing reactors all function best with materials that behave predictably. There were years where my role focused almost entirely on scaling research concepts to manufacturing, and materials that clumped, changed color, or required frequent re-testing lost us time and money. 4-Hydroxybenzoic Acid lent a comfortingly familiar performance profile that let us scale up projects and meet regulatory milestones with fewer hiccups.
Quality managers look for easy wins, and the presence of a high-grade, low-impurity acid usually signals fewer problems downstream. It’s distinct from the frustration of working with “commodity” chemicals, where grades and specifications can jump between orders. This consistency pays off in both time saved and reduction of process deviations, often measured in added hours or material cost savings – but just as often, measured in lowered stress and higher staff morale. Teams working long hours want to rely on the backbone of their product line.
Every widely used chemical wades through cycles of scrutiny. Parabens, derived from 4-Hydroxybenzoic Acid, have attracted headlines over a possible connection to health risks, most notably the ongoing debate around hormone disruption. Scientists continue to examine data, and as of today, large-scale reviews by recognized agencies support the view that parabens – at levels permitted for use – present a low risk to human health. Importantly, the parent acid itself is not a paraben and doesn’t carry these same concerns when used as a synthetic building block or intermediate.
Environmental impact also enters the conversation. The chemical industry faces growing pressure to develop greener synthesis methods and fully document the lifecycle of their products. As a result, many suppliers have shifted to bio-based routes or improved catalytic systems that reduce energy use and waste. From a user’s perspective, asking suppliers direct questions about their sourcing and production practices represents a practical step toward more responsible procurement.
Across the spectrum – from medicine to plastics – buyers want more than a bottle of fine white powder. They want confidence, documented safety, and an ability to answer tough questions from regulators and the public alike. 4-Hydroxybenzoic Acid, by virtue of its broad documentation and track record, provides just that.
Discussions about upgrading product lines often circle back to supply consistency and cost. In regions where raw material purity varies, manufacturers sometimes face additional purification steps, lab testing, or even supplier changes that can wreck production timelines. For companies that plan on scale, building solid relationships with reputable suppliers of 4-Hydroxybenzoic Acid translates directly into fewer process headaches and lower indirect costs.
Another avenue for improvement has emerged through technological advances in process chemistry. Catalysts and improved reactor designs help lower environmental footprint and energy demand, all while tightening control over final purity. Industry pushes toward continuous manufacturing – rather than old-fashioned batch production – reflect a commitment to efficiency and quality, both of which suit a compound with the versatility and flexibility of 4-Hydroxybenzoic Acid.
Digital tracking systems now allow full documentation from raw material delivery all the way through product shipment. Traceability, in this age of rapid recalls and consumer activism, is more than a corporate buzzword. It forms the backbone of confidence for major brands and regulatory agencies. Companies that invest here set themselves apart, whether making pharmaceuticals or consumer goods.
It’s easy to treat chemical buying as an exercise in price comparison, but that approach misses the larger impacts on safety and final product reliability. Analytical data – not glossy marketing – reveals the true value of a lot of 4-Hydroxybenzoic Acid. Independent testing using HPLC, NMR, and IR spectroscopy guarantee that the reported identity and purity stand up to rigorous review.
Many global markets now require testing for heavy metals and other potentially hazardous residues in every shipment, regardless of intended use. Pharmaceutical producers demand raw materials low in pyrogens and free from microbiological contamination, as even trace levels can derail a drug application. Quality-minded suppliers know that a well-documented data package isn’t just a selling point – it’s a regulatory necessity.
Reputable sellers perform extra testing and make their results available, a practice that has largely become standard due to pressure from large buyers in Europe, North America, and Asia. The rollout of more stringent global standards is adding additional momentum to this trend. International trade demands that products such as 4-Hydroxybenzoic Acid clear customs with ease, so thorough documentation must travel along with the physical product.
Practical challenges pop up all along the supply line. Import delays, purity discrepancies, and miscommunication between supplier and manufacturer still rear their heads. Drawing from my own experience in chemical procurement, the best approach always starts with building solid relationships. Talking directly with suppliers, visiting production sites, and ordering advance samples for test runs short-circuit many common problems.
Feedback loops between purchasing, quality control, and production matter. Claims of “pharmaceutical grade” or “food safe” only pay dividends when they survive on-the-ground testing. Internal documentation must track vendor batches and link every shipment to a corresponding certificate of analysis. If an issue does arise – say, a spike in trace metals or inconsistent particle size – quick action and honest dialogue with suppliers solve the root cause much faster than internal blame games.
Smart buyers stay updated on regulatory trends, gathering up-to-date safety data and keeping communication open with government or industry groups. Fact-finding missions and continuing education keep both companies and individual buyers nimble as standards shift. The burden of compliance rests as much on the buyers as the sellers, so staying proactive often counts more than demanding guarantees after a problem appears.
14 years into my chemistry career, I’ve seen ingredient sourcing go from a sleepy, low-tech chore to a frontline focus of innovation and brand reputation. The story of 4-Hydroxybenzoic Acid perfectly illustrates the reality that a single raw material – if clean, consistent, and well-documented – can smooth out the complexity in downstream processing. This gives manufacturers a stronger hand in regulatory environments that expect transparency and safety.
Companies looking for long-term success should keep up with advances in both analysis and green chemistry. Working with suppliers who trace batches, report test data up front, and join industry trends in sustainability puts a company’s products on stronger ground – legal, environmental, and reputational. Transparency builds confidence with both regulators and customers, whose trust can make or break a brand in the age of social media.
4-Hydroxybenzoic Acid remains a workhorse because it meets these high expectations with a balance few competitors manage. It offers chemists, buyers, and quality managers confidence and adaptability, while ongoing advances in sustainability and documentation continue to increase its value. As always, products and reputations built on a solid foundation of good science and practical transparency tend to stand the longest.