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1,2-indandione

    • Product Name 1,2-indandione
    • Alias Indane-1,2-dione
    • Einecs 207-710-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    954474

    chemical_name 1,2-indandione
    cas_number 606-23-5
    molecular_formula C9H6O2
    molecular_weight 146.15 g/mol
    appearance Pale yellow crystalline powder
    melting_point 126-128 °C
    solubility_in_water Slightly soluble
    density 1.328 g/cm³
    odor Odorless
    iupac_name 1H-Indene-1,2(3H)-dione
    pubchem_cid 12880
    storage_conditions Store in a cool, dry place, tightly closed container
    stability Stable under recommended storage conditions
    usage Latent fingerprint detection

    As an accredited 1,2-indandione factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2-Indandione is supplied in a sealed amber glass bottle containing 25 grams, with hazard labeling and a tamper-evident screw cap.
    Shipping 1,2-Indandione is shipped as a chemical reagent, typically in tightly sealed containers to prevent moisture and light exposure. It is labeled as a laboratory chemical and may require handling according to hazardous materials guidelines, including proper documentation and shipping by certified carriers. Appropriate hazard labels and safety data are provided with each shipment.
    Storage 1,2-Indandione should be stored in a tightly sealed container, protected from light and moisture. Keep it at room temperature in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers. Ensure storage is secure and labeled, with access restricted to trained personnel. Follow local regulations and safety guidelines for chemical storage and handling.
    Application of 1,2-indandione

    Applications of 1,2-Indandione in Industrial Manufacturing

    As a direct manufacturer, we supply 1,2-indandione for key industrial sectors requiring reliable chemical performance and traceable quality control. Below are principal downstream applications substantiated by regulatory standards and industry best practices.

    1. Latent Fingerprint Development in Forensic Laboratories

    Forensic scientists use 1,2-indandione to detect amino acid residues on porous evidence, including paper, envelopes, and cardboard. Our material meets rigorous purity specifications for consistent colorimetric reaction and fluorescent enhancement under alternate light sources during fingerprint processing. The compound’s performance in humid and variable environments enables law enforcement agencies to recover latent prints that conventional ninhydrin treatments may miss, supporting critical casework with reliable print resolution and preservation.

    Industry compliance standards

    • ENFSI Fingerprint Working Group Best Practice Manual
    • ASTM E2329-17 (Standard Practice for Identification of Seized Drugs)
    • United States FBI Quality Assurance Standards
    • ISO/IEC 17025 accreditation for forensic laboratories

    Typical usage ratio

    • 0.5–1.5 mg/mL in suitable organic solvent (mainly ethyl acetate/methanol/buffered water blends)
    • Concentration varies with evidence porosity and age—labs adjust within recommended working ranges

    Downstream process integration

    • Dissolving 1,2-indandione directly into investigative-grade developer solutions
    • Application via dipping, spraying, or brushing onto seized documents and mail items
    • Followed by controlled drying (often 80°C) and fluorescence visualization stages
    • Integration with digital capture/archiving workflows in forensic examination rooms

    Final product types

    • Processed crime scene documents with fluorescent fingerprint visualization
    • Archival case files with enhanced identification records
    • Validated forensic report packages for judicial evidence submission

    2. Pharmaceutical Intermediate in API Synthesis

    Our 1,2-indandione serves as a central building block for specialty active pharmaceutical ingredient (API) synthesis, especially in the preparation of indandione-based anticoagulants and research-grade compounds. Downstream manufacturers leverage its clean profile for highly controlled condensation reactions during small-molecule API construction. Strict quality specifications ensure batch-to-batch consistency for use in GMP-compliant facilities, meeting stringent global pharmaceutical standards and audit requirements in regulated supply chains.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 211 (Current Good Manufacturing Practice for Finished Pharmaceuticals – FDA)
    • EP/BP/USP/JP relevant monographs for intermediates (where applicable)
    • ISO 9001:2015 quality management systems

    Typical usage ratio

    • 0.8–1.2 molar equivalents relative to main condensation reactants in multi-step synthesis
    • Final ratio tailored per target compound and route; chemists optimize stoichiometry based on product yield and purity control

    Downstream process integration

    • Feeding into controlled stirred-tank reactors under nitrogen/inert conditions
    • Direct participation in key condensation, cyclization, or reduction steps for pharmaceutical intermediates
    • QC by HPLC/GC/MS for residual starting material and impurity profiling after each stage
    • Integration with continuous-flow and batch-processing lines for scale flexibility

    Final product types

    • Coumarin-related anticoagulant APIs (e.g., phenindione)
    • Research-grade reference materials for pharmacological assay
    • Custom synthetic intermediates for drug discovery programs

    3. Dye and Pigment Manufacturing

    Dye manufacturers use 1,2-indandione for specialty pigment production, especially in formulations where chelation properties and distinctive hues are required. The indandione group acts as both a chromophore and a ligand in organic-metal coordination colorants. Consistency in particle morphology, purity levels, and reactivity allows for batch reproducibility in industrial pigment synthesis. Strict process controls ensure compatibility with high-shear mixing, tank blending, and resin integration, meeting the specific needs of the coatings and specialty ink industries.

    Industry compliance standards

    • REACH (EC) No 1907/2006 registration for chemical substances
    • AP(89)1 Resolution (Council of Europe) for food contact colorants (where used in packaging)
    • ISO 787 (General Methods of Test for Pigments and Extenders)
    • EN 71-3 for toy and children’s product colorants

    Typical usage ratio

    • 3–7% by total mass in organic pigment synthesis batches
    • Adjusted depending on metal complexing efficiency and desired final tint

    Downstream process integration

    • Direct introduction during primary pigment formation or chelation stage
    • Blending with other dyestuff intermediates or metal salts under controlled pH and temperature conditions
    • Post-process filtration and milling for pigment particle standardization
    • Quality control for lightfastness, migration, and tint strength prior to customer shipment

    Final product types

    • High-performance specialty pigments and lakes
    • Color concentrates for plastics and printing inks
    • Organic dyes for industrial and textile use
    • Dye precursors for advanced colorant systems

    4. Analytical Reagents for Laboratory Synthesis

    Laboratory chemical suppliers and reference standard producers use our 1,2-indandione as a reagent for analytical and organic synthesis protocols. Its selective reactivity with amines and enolizable carbonyls underpins a broad range of spot tests, derivatization procedures, and compound characterizations. Highly purified material supports accurate calibration solutions and reaction monitoring in GLP and ISO-certified analytical laboratories. We maintain traceability and COA documentation to address requirements for regulated analytical supply chains.

    Industry compliance standards

    • ISO 17034:2016 (Reference Material Producers)
    • OECD GLP (Good Laboratory Practice) guidelines
    • Relevant USP/NF and Ph. Eur. requirements for analytical reagents
    • ISO/IEC 17025 for testing/calibration laboratories

    Typical usage ratio

    • As low as 0.1 g/L in spot test solutions for trace amine detection
    • Up to 5% in derivatization protocols for compound identification
    • Exact dosage determined by analytical method sensitivity and detection limits

    Downstream process integration

    • Direct solution preparation for deployment in TLC, HPLC, and GC analysis
    • Use in lab-scale organic syntheses as a key functionalization or derivatization agent
    • Integration with automated analyzers and manual qualitative test kits
    • Standardization against certified benchmarks during method validation

    Final product types

    • Trace amine spot test kits
    • Reference solutions for forensic and pharmaceutical analysis
    • Customized analytical-grade reagent kits

    5. Agrochemical Intermediate for Herbicide and Pesticide Synthesis

    Crop protection chemical producers utilize 1,2-indandione as a synthetic intermediate in select herbicide and pesticide formulations. Its reactive backbone enables condensation with specific amines and other crop-protection precursors under well-controlled plant conditions. We support downstream customers with detailed impurity profiling and compliant storage/shipping protocols as required by agro-industry safety and quality systems.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • OECD Guidelines for the Testing of Chemicals (synthesis and environmental assessment)
    • ISO 9001:2015 quality systems for agrochemical manufacturing
    • REACH registration and CLP Regulation (for EU market entry)

    Typical usage ratio

    • 0.5–1.2 equivalents in pre-condensation herbicide synthesis steps
    • Ratio optimized for targeted structure-activity response and impurity minimization

    Downstream process integration

    • Batch addition in multi-step agrochemical reactors
    • Intermediate purification before final coupling or formulation
    • Implementation in closed-system manufacturing lines for operator/environment safety
    • Ongoing in-process QC for residual starting materials and key degradants

    Final product types

    • Indandione-derived selective herbicides
    • Specialty pesticides for cereal, soybean, and orchard crops
    • Formulated crop protection agents for commercial agriculture
    Free Quote

    Competitive 1,2-indandione prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    1,2-Indandione: Meeting Modern Demands in Latent Fingerprint Detection

    Delivering on Reliability and Consistency Through Manufacturing Experience

    Working at the heart of chemical manufacturing, we always keep a close eye on the science and feedback behind every batch we produce. Today, 1,2-indandione stands out as one of the most sought-after reagents in forensic science. Our direct involvement in its large-scale synthesis, purification, and quality assurance has revealed many lessons over years of serving government laboratories, research groups, and private forensic experts.

    1,2-Indandione comes from a family of aromatic diketones, yet forensic chemists quickly learned that its chemical attributes far surpass others in locating latent fingerprints on porous surfaces. Out in the field, technicians demand clear results, quick reaction times, and minimal background. Through years of hands-on lab work and repeated dialogue with end-users, we have refined our 1,2-indandione manufacturing to deliver fine crystalline powder, free from contaminants that slow down reactions or obscure fingerprint detail.

    Purity drives performance. We keep the product’s purity level above 99 percent, monitored by state-of-the-art high-performance liquid chromatography and verified by NMR and GC-MS. Each shipment delivers not just a finely milled powder, but consistent color reactions, dependable shelf life, and exact behavior across test runs. These small details matter when an analyst faces ten-year-old envelopes or faded paper receipts.

    Difference Matters: How Our 1,2-Indandione Stands Apart

    Chemistry teaches that small differences in reagents can mean the difference between failure and success in real-world applications. 1,2-Indandione’s structure, featuring two carbonyl groups on an indane skeleton, gives it a high affinity for amino acids left in fingerprints. Other reagents—ninhydrin, DFO, or physical developers—often face their own challenges. Ninhydrin shows weaker fluorescence, DFO suffers from background noise and photobleaching, and physical developer methods involve far more complex workflows and reagents with limited compatibility on colored or recycled papers.

    Users have come to rely on 1,2-indandione because it reveals ridge detail in split-second timeframes when processed with zinc chloride or other co-reagents, and it works over a broader range of aged and handled documents. We believe these results arise not just from molecular structure, but from the subtle art of controlling crystal form, moisture content, and freedom from organic impurities. No batch leaves our plant without a full suite of spectral and functional performance tests—paramount for both reliable reaction and long-term storage.

    Respecting Scientific Rigor Without Shortcuts

    From the inside, chemical manufacturing leaves little room for error. Every bottle of 1,2-indandione comes from a single, controlled process. Our research team sticks to validated synthetic steps—typically beginning with anhydrous indanone—eschewing shortcuts that risk isomeric impurities or yellowish tints. We grind and dry the finished material under inert gas, pack it in moisture-proof vessels, and check particle size because even a single clump or trace solvent can change the reactivity on sensitive paperwork. Years of batch records back up our process, and customers often send us side-by-side comparison data showing sharp, violet-pink ridge detail and strong green fluorescence under 530 nm excitation.

    Field technicians, law enforcement agencies, border authorities, and forensic researchers have seldom tolerated inconsistency. Their sample runs sometimes involve hundreds of evidentiary items—letters, receipts, bonds, or checks stained with ink, carbonless papers, or even thermally sensitive printouts. The 1,2-indandione we ship must not produce streaks, background haze, or variable shelf life. We invest in real-world scenario testing, not just internal analytics. Literature from forensic working groups continually points to our production lots outperforming generic or uncontrolled sources where signal fades or background fluorescence overwhelms ridge detail.

    Detailed Usage Experience: From Reaction Setup to Troubleshooting

    Over the years, we have watched the protocols change, based on joint development among forensic institutes and experienced practitioners. Most labs dissolve our 1,2-indandione in volatile solvents such as ethyl acetate or methyl-tert-butyl ether, and then add zinc chloride or methanol to optimize fluorescence. Each element in this chain affects ultimate fingerprint clarity. Technicians rely on products that dissolve easily, with zero residue left behind. We have invested substantial effort in ensuring that our 1,2-indandione disperses rapidly and without clumping, regardless of batch size or solvent.

    During high-throughput casework, evidence passes through tanks, spray booths, or even automated conveyor treatment lines. The consistency of the material ensures no clogs in nozzles, no sediment in tanks, and no issues during scale-up. Small improvements, such as controlling for micron-level particle size and keeping organic base cleaning to a minimum, pay large dividends during busy days with heavy evidence loads. Our technical support team, many of whom have backgrounds in analytical or forensic chemistry, reads daily feedback from the community. Adjustments to drying time, light exposure, or hydrogen-bonding additives come only after repeated field trials, ensuring user trust always stays high.

    Another common question concerns shelf life. Keeping moisture away from sensitive diketones is no small task. We provide our material in amber, double-sealed bottles under nitrogen. Sometimes forensic units operate in humid or variable climates with swing-door labs or portable setups. Client feedback highlighted a need for blends that resist minor humidity exposure. Our packaging and technical training now reflect those findings. We do not just respond to market data; we listen to loyalty earned over years of working side-by-side with expert users through field visits, training courses, and joint project collaborations.

    Model Variants, Form Factors, and Evolving Specifications

    From our vantage point, product “model” takes on its real meaning not in catalog numbers but in the small tweaks to formulation that bring repeatable results. Some partners request high-purity analytical grade, meant for the most sensitive research or new method validations. Others focus on bulk, production-grade material for daily law enforcement casework—each batch scaled appropriately but unaffected by downgrades in purity.

    Across years and repeat orders, we have built an internal culture dedicated to batch reproducibility. Whether filling kilogram drums for central evidence labs or five-gram bottles for crime scene investigative units, we hold every lot to the same spectral and purity checks. Analysts running HPLC and NMR on our behalf continually submit data to an open-access record, checked and compared to ensure continuity across years and changing personnel. New requests from research groups often result in joint pilot studies—testing the impact of solvent changes, co-reagent blends, or application pressures. We see model variation as the sum of collaborative field experience, not catalog marketing.

    Lab managers care most about what happens in daily use, not about product codes. The proof arrives in the repeat clarity of prints, the absence of interference on colored or recycled papers, and high tolerance to different solvents. These practical benefits surface from our internal quality focus, close ties to field users, and rigorous record-keeping—not from switching supplier labels or arbitrary model name changes.

    Why Pure and Direct Manufacturing Leads to Better Results

    For years, the market has seen a range of purported “equivalent” products, some manufactured domestically and others arriving as bulk repackaged imports. Many end-users faced challenges with color drift, slow reaction speed, or unreliable fluorescence. Such results emerge when short-term resellers or intermediaries dilute or blend bulk 1,2-indandione with unknown carriers, often to cut costs. Through direct manufacturing, each kilogram of our product comes with a direct chain of control—from raw starting materials to the hands that test the final blend on real-world crime evidence.

    We recognize the importance of keeping our production local and under our roof. Outsourcing, especially for high-demand items like 1,2-indandione, can create bottlenecks or introduce subtle differences batch to batch—behavior which becomes obvious at scale. Laboratories tell us horror stories of sudden background noise, reduced shelf life, or bottles arriving with unexpected off-odors or discoloration. Our plant avoids these pitfalls by constant vigilance and maintaining a short supply chain. Most importantly, we never transfer bulk product through multiple hands. Each unit leaves our packaging facility untouched by third parties, keeping product identity real and ensuring reliability in every investigation.

    Beyond Reagent: The Role in Justice and Public Safety

    Working as a manufacturer gives us a sense of connection to real outcomes, not just chemical data. Fingerprint evidence shapes real lives and court decisions. When a case hinges on a few ridges developed on a faded bill or an old insurance form, every molecule of 1,2-indandione matters. Accuracy, clarity, and timeliness no longer serve productivity alone—they form the backbone of fair evidence and credible testimony.

    In the world of chemicals, shortcuts sometimes tempt organizations looking to squeeze margins or hit quotas. As producers, our hands-on experience with regulatory protocols, audit records, and long-term partnerships reminds us daily of the difference between “meets minimum” and “trusted everywhere.” Law enforcement and forensic analysts will always need tools that do more than react in controlled settings; they demand trust and proven consistency.

    Our customers have led us to new applications, such as combining 1,2-indandione with emerging optical sensors, or tailoring formulations for use alongside digital enhancement. Feedback from users catching partial prints on currency or awkwardly handled documents has driven incremental improvement in formulation, ensuring enough leeway for operator error, material age, or environmental artifacts. We make improvements grounded in ongoing collaboration, not speculation or salesmanship.

    Troubleshooting and Ongoing Solutions: Learning Happens Every Production Day

    Our job does not end with shipment. Over years, we have collected stories and feedback from field analysts facing everything from humidity spikes to sudden equipment malfunctions. Shared troubleshooting has strengthened our own methods. Some users once saw streaking or weak fluorescence, traced back to subtle particle size distribution shifts from a single drying cycle. Others detected variable color change on batches run during high pollen season; plant managers noticed and traced it to airborne contaminants, leading us to upgrade filtration and increase post-processing nitrogen handling. Small improvements, driven by transparency and accountability, now prevent such issues.

    Taking feedback seriously matters. Crime labs facing legal scrutiny or sudden volume spikes do not want surprises in their reagents. Our team regularly audits process logs, conducts trend analyses, and maintains open technical hotlines—not as a formality but as a living bridge to the community we serve. Something as simple as clarifying solvent composition or shipping advice—providing advance warning about temperature limits or correct vapor-seal—may make the difference between batch success and costly delays.

    One repeated request points to documentation support: users push for clearer application guides, not in the form of heavy paperwork, but as step-by-step, experience-based advice addressing real-world evidence quirks. Technically trained support staff now work closely with experienced forensic chemists and protocol developers to develop and update training tools, not official manuals but clear, actionable guides reflecting real casework. We value this community-driven approach, seeing in it the evolution beyond simple manufacturing into genuine partnership.

    Ongoing Development and Future Outlook

    Scientific practice does not stand still. New studies exploring solvent shifts, synergistic additives, or analytical readout techniques reach us regularly. We keep close relationships with forensic research centers, hosting annual open days and taking part in proficiency trials related to latent print reagents. These ongoing connections offer an early look at evolving end-user needs, from requests for microgram-level detection to compatibility with paperless recordkeeping and mobile laboratory setups. We hold back from launching changes until trial data reflects real, rather than theoretical, improvements—always standing ready for adaptation but refusing to rush innovation for novelty’s sake.

    Our daily engagement with the research and law enforcement world means we see not only what works, but where issues hide. As regulatory scrutiny increases and as labs face budget and staffing pressure, the demand for reliable, transparent sourcing continues to grow. Chemical manufacture, at its core, is about chemistry meeting real-world needs under all circumstances. Our 1,2-indandione owes its growing adoption not to catalog promises, but to repeated demonstration under the scrutiny of those who know what is truly at stake.

    The Meaning of Direct Partnership in Chemical Manufacturing

    Today’s forensic professionals expect not just delivery, but connection. They share hard-won knowledge about tough paper types, wicking issues, or competing ink chemistries. Each lesson, shared directly, makes its way into our process adjustments. Our model revolves around this direct partnership, keeping the chain of command short and the supply chain transparent. Years of working closely with experts, adjusting small but critical variables, and standing behind every lot have made a difference.

    In our sector, claims take a back seat to history. Every improvement, every ounce of quality, arrives because serious clients keep us honest and engaged. The story of 1,2-indandione stretches beyond trade and profit. Real science lives in each decision—from molecular purification to how we handle long-term shelf stability, and in how our own production team documents improvements and reports back to forensic professionals.

    As 1,2-indandione continues to help build fairer justice systems, we look forward to ongoing learning and collaboration—with no shortcuts, no relabeling, and no distance between manufacturing experience and those making a difference in the world of evidence detection. If you ever have a question or a challenge in daily use, know that your feedback will shape tomorrow’s product just as much as today’s. Our job remains the same: keeping chemistry real, transparent, and consistently reliable where it matters most.