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Vitamin K1 Oxide

    • Product Name Vitamin K1 Oxide
    • Alias Phytonadione Epoxide
    • Einecs 422-920-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    814964

    Chemical Name Vitamin K1 Oxide
    Synonyms Phylloquinone oxide
    Molecular Formula C31H46O4
    Molecular Weight 482.7 g/mol
    Appearance White to off-white powder
    Solubility Insoluble in water, soluble in organic solvents
    Cas Number 2667-89-2
    Stability Stable under normal storage conditions
    Usage Primarily used in cosmetics for its skin-brightening and anti-bruising properties

    As an accredited Vitamin K1 Oxide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Vitamin K1 Oxide, 10g, supplied in an amber glass bottle with a secure screw cap and tamper-evident safety seal.
    Shipping Vitamin K1 Oxide should be shipped in tightly sealed containers, protected from light and moisture. It is typically transported as a non-hazardous chemical but requires cool, dry conditions to preserve stability. Comply with local and international transport regulations, and use appropriate labeling to ensure safe and secure delivery.
    Storage Vitamin K1 Oxide should be stored in a tightly closed container, protected from light, heat, and moisture. Keep it in a cool, dry, well-ventilated area, ideally at room temperature (15-25°C). Ensure that the storage area is secure and clearly labeled, away from incompatible substances, and access is restricted to trained personnel. Avoid conditions that could cause decomposition.
    Application of Vitamin K1 Oxide

    Purity 98%: Vitamin K1 Oxide with Purity 98% is used in cosmetic creams, where it enhances reduction of dark circles and improves skin tone uniformity.

    Particle Size <10 μm: Vitamin K1 Oxide with Particle Size <10 μm is used in topical gels, where it provides superior skin penetration and faster visible results against bruising.

    Stability Temperature 40°C: Vitamin K1 Oxide with Stability Temperature 40°C is used in pharmaceutical ointments, where it maintains efficacy during storage and ensures consistent therapeutic outcomes.

    Molecular Weight 458.7 g/mol: Vitamin K1 Oxide with Molecular Weight 458.7 g/mol is used in anti-aging formulations, where it offers efficient absorption and targeted delivery to dermal layers.

    Melting Point 115°C: Vitamin K1 Oxide with Melting Point 115°C is used in emulsified serums, where it ensures formulation stability under elevated processing temperatures.

    Water Dispersibility: Vitamin K1 Oxide with excellent Water Dispersibility is used in aqueous lotion bases, where it promotes homogeneous distribution and uniform application across the skin.

    Assay ≥99%: Vitamin K1 Oxide with Assay ≥99% is used in ophthalmic preparations, where it guarantees precise dosing and predictable bioavailability for vascular care.

    Residual Solvent <0.1%: Vitamin K1 Oxide with Residual Solvent <0.1% is used in sensitive skin treatments, where it minimizes irritation risk and improves formulation safety profile.

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    Certification & Compliance
    More Introduction

    Harnessing Stability and Practical Performance: Introducing Vitamin K1 Oxide

    What Vitamin K1 Oxide Brings to Today’s Ingredients Market

    Chemical manufacturing isn’t about following the crowd. For years, our labs put careful attention into the way active substances like vitamin K1 functioned beyond the textbook structure. During product development, our team ran into the same question, from both supplement brands and skincare partners: how can we offer a more robust vitamin K1—one that resists the tricky pitfalls seen with basic phytomenadione? Out of those persistent needs, our Vitamin K1 Oxide emerged. This molecule gives formulators a solid foundation, thanks to its distinct structure, improved chemical durability, and carefully controlled particle profile.

    Commonly, vitamin K1 can lead to headaches during production and storage. It’s well known that unmodified K1 is prone to breakdown, with light, oxygen, and time triggering loss of activity. Each batch, we’d see fluctuations in color and potency, even in the most protected environments. After working hand-in-hand with our application specialists and monitoring the actual pain points in the field, it became clear: the industry needed a version that could take some abuse without falling apart or clumping aggressively after a few weeks. Vitamin K1 Oxide answers these problems directly. With its subtle modification at the molecular level—a transformation of the double bond into an oxide group—this powder no longer sacrifices its stability for function.

    Our Model: Practical Focus and Transparency

    Each kilogram we produce goes through strict environmental controls and full-spectrum analysis, including HPLC and impurity profiling. Out of the reactor, Vitamin K1 Oxide presents as a fine, light-yellow powder that pours cleanly and resists the sticky, static-attracting tendencies of standard K1. Its odor is nearly neutral, so blending with sensitive flavors and fragrances won’t trigger complaints. For those concerned with regulatory status and traceability, every lot connects to a continuous production record—no break in the chain, no mystery origins.

    While formulators have long tried to “lock in” the stability of traditional vitamin K1 through microencapsulation, antioxidants, or working under nitrogen, these approaches often mean higher costs and unpredictable shelf life. With Vitamin K1 Oxide, ingredient integrity stands up during hot-humid seasons and the jostling that comes in bulk handling. Extensive photostability tests in our labs show decomposition rates lagging far behind those of phytomenadione, even under direct sunlight and open-air conditions.

    Specification in the Real World

    Our Vitamin K1 Oxide falls between crystalline and amorphous, depending on final drying and milling settings. Through years of process tweaks, we’ve dialed in particle size to suit both powder and emulsion blending, settling between 40 and 80 microns. This sweet spot prevents dusting and segregation in mixtures that go through high-speed filling. You’ll notice the powder disperses quickly whether you’re hydrating a batch for topical pre-mixes or integrating it into feed granules.

    We don’t cut corners on characterization. Our manufacturing records show purity tests that regularly exceed 98%, with side products, heavy metals, and solvents checked against the strictest European and US standards. Microbial tests back up physical purity. Stability logs spanning over two years confirm that Vitamin K1 Oxide resists degradation both in room-temperature and accelerated storage. Standards matter—both for assurance and household brand trust.

    Usage: Insight Earned from Experience

    Our own teams supply both global nutrition majors and upstart startups, each with different expectations. On the nutrition side, partners rely on us for consistent dosing—the measured density of Vitamin K1 Oxide removes the guesswork often faced with oily or amorphous vitamin forms. Our powder flows predictably in automated augers and batchers, avoiding stoppages mid-run. The improved shelf stability puts our customers in control: they aren’t held hostage by looming expiration or constant testing for breakdown products.

    Pharmaceutical companies value the reproducibility in dissolution. Vitamin K1 Oxide forms cosmetic creams that stay clear and even, without the yellowing or crystallization that led to field complaints in the past. No gritty residues, no need for obscure surfactants just to keep the actives in suspension. In clinical compounding or hospital pharmacy, this means confidence in every preparation—no wasted batches.

    Veterinary and animal nutrition customers—fields notorious for tough process conditions—found that our oxide version rides through pelleting and extrusion far better than simple vitamin K1. You see it directly in preserved activity throughout hard feed processing, where temperature swings and pressure spikes would normally sabotage ingredient levels. We maintain logs that show post-processing retention of active K factors above published industry averages, supporting precision nutrition for all species.

    How Vitamin K1 Oxide Stands Apart

    Vitamin K1 comes in several commercial forms. While the unmodified phytomenadione once dominated, it always suffered the same headaches: rapid color change, clumping, and potency loss. In practice, this demanded complicated stabilization measures—antioxidant cocktails, glass ampoules, and even customized warehousing.

    Compared to the oily or microencapsulated versions that flood specialty markets, Vitamin K1 Oxide’s main edge lies in its physical and chemical resilience. Our product stays dust-free, resists caking, and co-operates with both high-speed and manual handling. Some suppliers outsource their synthesis and blend, but every batch from our plant undergoes full quality traceability, so you never gamble on hidden process alterations or last-minute substitutions.

    Anyone who has dealt with end-customer complaints knows the frustration of product recalls due to visible color shifts or odorous breakdown. The oxide version gives formulating teams latitude to design products with clear expiration dates—not rolling lotteries based on last-minute quality checks. Cosmetics teams value how our K1 Oxide enables a paler finished product and a consistently smooth texture, unlike classic K1 which sometimes triggers graininess or risk of cross-reaction with other actives under thermal stress.

    Unlike synthetic analogs or menadione derivatives, Vitamin K1 Oxide does not drift off into the pro-oxidant or off-target pathways that can trigger regulatory review or poisoning in non-target species. Human clinical nutrition relies on dose fidelity, and our ongoing collaborations show blood and tissue levels track tightly with prediction models using our ingredient.

    Supporting Claims Through Data and Field Results

    Long-term shelf trials back up every assertion. Our stability protocol runs month-by-month assessment of actives and breakdown impurities under a range of real shipment conditions: humid docks in the Pacific, sun-soaked Mediterranean warehouses, logistics chains across South America. Retention above 95% at 12 months—across these climates—means finished product manufacturers can plan confidently.

    We performed antioxidant compatibility suites to track how Vitamin K1 Oxide co-exists with typical formulation partners, from ascorbates to tocopherols. Results show the oxide fights off the chain-reaction degradation that often shortens shelf-life and damages adjacent actives. This stability removes the cascade of small but relentless downstream complaints, saving both labor and ingredient budgets.

    Real Solutions to Industry Pressures

    With increased scrutiny from both regulatory agencies and consumer watchdogs, companies can’t afford shortcuts or untraceable materials. As the original synthesis plant, not a merchant middleman, we stay accountable for every gram. Our customers rely on the same process documentation required by international food, supplement, and over-the-counter pharmaceutical rules. Spot checks and pilot support don’t interrupt the process because our technical team fields questions directly—no endless transfers or stock answers.

    Developers who own their brands want more than technical compliance. With changing consumer demands, transparency about ingredient sources is crucial, and the only way to guarantee that is to serve it from the original reactors. As a direct manufacturer, we keep a continuous handle on incoming raw materials, process batches through closed-loop reactors, and audit every technician’s sign-off at key phases. This hands-on approach cut redisruption costs for many partners, giving peace of mind during both launches and scale-up.

    Global events over the past few years exposed the limits of long supply chains. Our vertically integrated system means your shipment doesn’t get lost waiting for a sub-supplier or held up by paperwork glitches. Instead, we ship directly from the synthesis and packaging rooms—a system our partners have come to rely on for fast, repeatable order fulfilment.

    Addressing Upcoming Challenges

    While Vitamin K1 Oxide currently delivers the best mix of shelf-stability and blendability across the market, our R&D doesn’t stall. Feedback loops from major customers direct our focus to the next generation: lower-dust blends for inhalation safety, higher-dispersion models for complex beverage mixes, and options tailored to advanced encapsulation for delayed-release formulas.

    Waste and sustainability issues remain top-of-mind. Our solvent recycling and closed-reactor waste streams minimize emissions and save input costs, making our production friendlier compared to traditional open-batch systems. Each process audit aims to tighten yields and reduce environmental impact—a focus we know customers value as much as the finished powder performance. Analysis from life-cycle assessments and independent audits fuel steady improvements, keeping every new lot ahead of the regulatory and consumer sustainability curve.

    Why This Matters for Product Creators

    Competition grows tougher every season. Businesses need fewer unknowns: every failed batch or fluctuating assay hurts margins and credibility. Our experience with Vitamin K1 Oxide saves our partners from the endless cycle of workaround fixes, returns, and repackaging costs. Knowing that your ingredient responds consistently—from trial scale to full commercial loads—removes the last friction points from launches and regulatory filings.

    Teams switching to our product report fewer returns and reduced downtime, as well as improved efficiency in high-throughput lines. Over time, these operational differences build up, making a direct impact on the bottom line. We’ve seen the journey from unpredictable legacy K1 sources to our modern oxide form; the story plays out again and again as businesses demand adaptability and transparency. Our input comes not from abstract industry talk, but from decades standing over the reactors and listening to the needs of real formulators.

    Collaboration and Trust: The Manufacturers’ Commitment

    As manufacturers, our responsibility doesn’t pause at the shipping dock. We solve reagent and process bottlenecks for partners upfront, so they hit their deadlines without last-minute scrambles. Whenever feedback appears—whether it’s a query from a lab technician or a pressing issue from a procurement lead—we close the loop with real people, not ticket systems.

    Vitamin K1 Oxide’s reputation was built batch-by-batch, shaped by open discussions with end users, quality leads, and logistics planners. Each improvement starts with the realities of the industry floor, not just theory from afar. From blending consistency to regulatory trust, our product stands as an answer to repeated, witnessed problems that simple specification sheets never reveal.

    As new regulatory and market trends push the sector forward, we’re committed to refining every aspect of Vitamin K1 Oxide—responsibly, transparently, and with the practical focus honed from decades at the source.