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(+)-Usniacin

    • Product Name (+)-Usniacin
    • Alias (+)-Usnic acid
    • Einecs 634-337-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    114583

    Name (+)-Usniacin
    Cas Number 125044-14-2
    Molecular Formula C18H16O7
    Molecular Weight 344.32 g/mol
    Appearance Yellow powder
    Purity ≥98%
    Solubility Soluble in DMSO, methanol
    Storage Temperature -20°C
    Iupac Name (6aR,9aR)-3,6,9-Trimethoxy-8-methyl-7-oxo-7,9a-dihydro-6aH-furo[3,2-g]isobenzofuran-1-carboxylic acid
    Synonyms L-usniacin, Usniacin, (+)-Usniacin
    Origin Lichen-derived natural product

    As an accredited (+)-Usniacin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing (+)-Usniacin, 1 gram: Supplied in a sealed amber glass vial with a screw cap, labeled with product details and hazard symbols.
    Shipping (+)-Usniacin is shipped in tightly sealed containers, protected from light and moisture, and typically at room temperature unless otherwise specified. It is packaged in accordance with relevant chemical safety regulations and includes proper labeling and documentation. Handling instructions and safety data sheets accompany each shipment to ensure safe transport and compliance.
    Storage (+)-Usniacin should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, ideally at 2–8°C (refrigerated temperature). Avoid exposure to heat, ignition sources, and incompatible materials such as strong oxidizers. Proper labeling and secure storage are essential to prevent contamination or accidental use.
    Application of (+)-Usniacin

    Purity 98%: (+)-Usniacin with purity 98% is used in pharmaceutical synthesis, where it ensures high efficacy and reduced side reactions.

    Melting Point 210°C: (+)-Usniacin with a melting point of 210°C is used in high-temperature formulation processes, where it maintains compound integrity during processing.

    Particle Size <10 µm: (+)-Usniacin with particle size <10 µm is used in topical dermatological applications, where it provides improved absorption and uniform distribution.

    HPLC Assay 99%: (+)-Usniacin with HPLC assay 99% is used in analytical standards preparation, where it guarantees accurate quantitative analysis.

    Stability up to 60°C: (+)-Usniacin with stability up to 60°C is used in thermally demanding storage conditions, where it prevents product degradation and ensures shelf-life.

    Optical Rotation +110°: (+)-Usniacin with optical rotation +110° is used in chiral synthesis workflows, where it contributes to stereospecific product outcomes.

    Moisture Content <0.5%: (+)-Usniacin with moisture content <0.5% is used in lyophilized pharmaceutical products, where it maintains chemical stability and prevents hydrolysis.

    Solubility in Ethanol 25 mg/mL: (+)-Usniacin with solubility in ethanol 25 mg/mL is used in solution-based extraction processes, where it enables efficient compound dissolution and recovery.

    Residual Solvent <10 ppm: (+)-Usniacin with residual solvent content <10 ppm is used in API production, where it complies with strict regulatory toxicology limits.

    Microbial Limit <100 CFU/g: (+)-Usniacin with microbial limit <100 CFU/g is used in injectable formulations, where it assures product sterility and patient safety.

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    Certification & Compliance
    More Introduction

    Introducing (+)-Usniacin: A Closer Look at a Specialized Raw Material

    Our Experience as the Direct Manufacturer

    Decades have taught us that producing niche chiral compounds requires a balance of precision, consistency, and genuine understanding of the chemistry involved. (+)-Usniacin, as our flagship product among chiral lactone derivatives, reflects this discipline. Every batch we ship depends on careful control from the earliest stage of fermentation or chemical synthesis through to the drying, purification, and packing process. People who work with this product in research labs and commercial production often ask what sets it apart, and the answer always returns to process control.

    Raw materials like (+)-Usniacin can’t be treated as commodities. Experienced chemists know the smallest impurity or shift in enantiomeric composition undermines not just the next synthesis or formulation, but the entire outcome down the line—be it a new drug or a specialty additive.

    A Product Built by Attention to Detail

    We manufacture (+)-Usniacin with a model that targets a meet-point of high purity and repeatability. Its chemical name, structure, and production route are documented with each lot. Specifications meet established analytical standards for enantiomeric excess, residual solvents, and moisture content. We measure optical rotation and run chiral HPLC (where applicable), and few shipment days go by where our QA team doesn’t come back with further tweaks. Over time, these continuous improvements drive consistency that many academic or pilot-scale producers struggle to achieve.

    Our standard lot carries a minimum assay above 98% by HPLC. Many clients require confirmed single-enantiomer purity, and the numbers rarely shift batch to batch. Each production record is backed by data from our own equipment—NMR, MS, and IR spectra included. All packaging comes completed without outside handling; we oversee the full process so customers avoid question marks about contamination or re-bottling that sometimes occur in distribution channels.

    There’s a lot said about supply transparency these days, but ours is direct: the same team that maintains the reactors signs the release documentation.

    Usage Across Diverse Applications

    Users in pharmaceuticals and chemical research often approach (+)-Usniacin for its role as a synthetic intermediate. Its chiral structure enables enantioselective synthesis routes, bypassing further chiral separation steps and making it an attractive building block for advanced organic molecules. Some companies pursue natural product analogues; others use it as a stepping stone toward active pharmaceutical ingredients. The breadth of use cases often surprises those outside the industry, but the real benefit emerges during process development scale-up, where highly reproducible intermediates simplify downstream optimization.

    Early-stage projects usually demand gram to kilogram quantities. As programs move forward, commercial preps turn to multi-kilo batches, and our production line is scaled to provide both scales without skipping steps or introducing cross-contamination risks. We run separate blending and packing areas for different enantiomers and monitor every transition between campaigns, so customers working under cGMP know that their requirements for traceability and audit support won’t get lost as volume grows.

    Formulation chemists refer to our published stability data when evaluating (+)-Usniacin’s behavior under various storage, solvent, and pH conditions. Each customer typically approaches our technical team for supplemental details—it’s common for them to replicate an experiment or recheck the melting point just to be sure. We welcome that. Many of our biggest customers started with one-off requests for data, and over time the trust grew.

    Beyond pharma, (+)-Usniacin also finds life as a specialty raw material in electronics and precision materials. Academics have used it in studies of stereoselective transformations. A few years ago, a researcher published on self-assembly patterns involving chiral lactones, and we supplied the starting material. Our technical staff fielded questions about batch-to-batch variation and customized moisture specification runs, highlighting the product’s ability to withstand rigorous academic or industrial scrutiny.

    What Sets Our (+)-Usniacin Apart?

    Buyers often face a crowded field, with products available from resellers, traders, and aggregator marketplaces. Most of those never see the inside of a reactor, and few are able to promise chain-of-custody traceability. Our difference lies in tight process integration and the ability to answer tough questions about production origins, not just logistics or compliance paperwork.

    The biggest difference arrives in the form of batch consistency and documentation. Many products sold by traders come repackaged, with original batch cards lost or missing. Some lots in the global supply chain have questionable origin; some even fail basic analytical tests when rechecked. Our offering avoids those pitfalls because our process is designed for minimal hand-offs. Every label, analysis report, and container matches the original batch campaign.

    We select our solvents and primary reagents with full records of each supplier’s compliance with contemporary global requirements, including hazardous substance declarations and banned chemical lists. Since we handle upstream and downstream processing, we never rely on outsiders to “white label” their own intermediates into our products. This traceability satisfies internal audits just as thoroughly as external partner verification, whether it’s a small start-up or a global conglomerate.

    Since we produce at medium scale, we avoid the variability problems that sometimes appear in pilot, lab, or artisanal batches. Our reactors see regular validation, maintenance, and cleaning, with all logs available. Manual operations are kept to a minimum, reducing human error risks.

    We maintain batch-specific documentation, including spectral data and full analytical traces, for customers who demand data reproducibility and regulatory readiness. Pharmaceutical sector customers often send their own auditors to verify the process, and we have grown to appreciate these visits—questions about in-process controls and raw material quality simply make our own operation stronger in the end.

    Packaging is sealed in controlled environments, with every container labeled to trace its entire production path. Whether somebody orders 50 grams for a pilot synthesis or a shipment of packed drums for a production campaign, the same principles apply. Each container is physically filled, weighed, and documented in-house. This may sound like extra work, but over the years we’ve found it eliminates confusion and rework when audits or user complaints later surface.

    Comparison with Other Chiral Building Blocks

    Unlike racemic lactone analogues, (+)-Usniacin delivers specific stereochemistry. Researchers often discover unwanted isomer formation or loss of optical activity when they try substitutes sourced from less controlled processes. Some competitors offer only racemates or synthetic variants with lower enantiomeric purity, requiring extra purification steps on the customer’s side. We keep the impact of chiral purity central to every process, as this aspect often determines whether a final product succeeds or fails.

    The product also contrasts with cheaper derivatives that bypass rigorous purification or attempt to mimic usnic acid derivatives using simpler fermentation without enantiomeric control. Over time, users learn that upfront cost savings turn into higher failure rates and more irreproducible results. Switching to consistent, well-characterized (+)-Usniacin solves many small headaches—reagent variability, inconsistent yields, even differences in product color and physical texture.

    Some in the market offer powdered or crystalline forms with varying solvent content. By contrast, our product is formulated with controlled particle size and constant moisture level, so process engineers and bench chemists alike can plan their runs without recalibrating or retesting each time. Our facility handles packaging under nitrogen or dry-air atmospheres if a project demands, because the fine points—trace water, dust, residuals—matter greatly during synthesis and scale-up.

    Supporting Innovation, Not Just Delivery

    Outside traditional applications, we see creative uses for (+)-Usniacin in specialized synthetic sequences. Custom analog development, catalysis experiments, and biomolecule conjugation are just some of the areas where small differences in product consistency translate to real project outcomes. Over the years, our technical service team has discussed stability, reactivity, and solubility—often engaging in collaborative troubleshooting with seasoned researchers.

    Our R&D group regularly interacts with longtime partners to refine the process. If a request arrives for a variant with a particular impurity cut-off, or a project needs fine-tuned solubility, we run trial campaigns. This direct feedback loop means our quality improvement isn’t dictated by abstract standards but by real requirements in the field. Case by case, success stories circulate back to us—a new method published with our material, a regulatory filing accepted, a milestone synthesis finally reached after months of supply failures elsewhere.

    Education centers and industry newcomers often approach us for smaller quantities and background data for their own prototyping. We share not only a direct link to our own production team, but also guidance on handling, storage, and compatibility questions learned from years of troubleshooting. Knowing exactly how the product performs under typical and stressful conditions gives newer users the foundation to plan and scale with confidence.

    A Direct Line Between Production and People

    Much of the market noise surrounding raw materials disappears if buyers know precisely where and how their product is made. Every employee here learns early that we don’t separate the people making, analyzing, and delivering (+)-Usniacin from the people using it. Decisions in our lab never happen without asking, “Does this address what our customers need for their process, safety, or success?” That’s why our own chemists, not just sales staff, answer technical calls.

    Feedback from users shapes each production cycle. If a pharmaceutical partner encounters a solubility shift, or a university team requests a different batch size, that request goes straight to operations, not into a ticketing queue with a secondhand representative. The value of this approach becomes obvious in situations where quick troubleshooting and data sharing prevent costly process interruptions or compliance issues.

    Transparency matters. Each lot ships with a full record, so users see not just the results, but also the exact production and analysis steps that shaped their material. Auditors, QA managers, and researchers reviewing their own supply chains regularly confirm that full traceability makes downstream work easier and more secure.

    Navigating Regulatory and Quality Challenges

    Regulatory compliance has grown more complex in recent years—especially for chiral raw materials that may enter either research or cGMP environments. Our own policies follow updated global standards for safety, labeling, and documentation. Every campaign includes GMP-friendly process logs and a full safety assessment matching the intended use. Our team invests in annual training and external audits, not just to check the boxes but to spot opportunities for tighter process control and risk mitigation.

    Customers in the pharmaceutical sector appreciate this foundation when they prepare for their own site inspections. We’ve hosted regulatory teams and follow up promptly when trace-level impurity, allergen, or packaging material questions arise. Most times the answers sit within our internal records, but we don’t mind running side-by-side analytical comparisons or batch-specific stability studies if required. Over the years, this policy has prevented costly recalls and regulatory surprises for both us and our customers.

    For users in less regulated sectors—advanced materials, custom synthesis, or academic R&D—the same standards apply even when external scrutiny is rare. Our practice of retaining ample reference material and data archives removes doubt and gives all users peace of mind when unexpected process changes or experiments come up years later.

    Addressing Common Issues and Solutions

    One recurring challenge in the chiral raw materials market involves unpredictable contaminants or unexpected by-products. Many buyers come to us after discovering that an earlier supplier couldn’t meet the same standards from lot to lot. Our continuous monitoring and in-house analysis shut down sources of error at an early stage. Routine upgrades to reactor cleaning, raw material sourcing, and documentation practices allow us to spot and remove batch variability before products reach customers.

    Supply chain disruptions remain a concern for project managers and procurement specialists everywhere. By relying on direct material sources and keeping local inventory management linked tightly to our main manufacturing site, we reduce the risk of stock-outs or long shipping delays. In the rare event of external force majeure, our regular communication policy keeps users informed and adjusts campaign schedules as needed, reducing the element of surprise and giving time for project rescheduling.

    Technical support is another area where we address ongoing pain points. Our team handles questions directly from the production area, so users receive prompt answers about solubility, compatibility with common solvents, and proper storage to avoid degradation or contamination. This on-the-ground practical advice has proven more valuable to researchers and production managers than generic information sheets or marketing brochures.

    Building Toward the Future

    Over the years, the landscape for specialized intermediates and advanced chiral molecules has shifted, with market demands outpacing many legacy manufacturing models. Our goal is to remain agile, adapting our production runs and technical support to customer needs as quickly as possible. Team members continuously learn and incorporate user suggestions. This process sometimes means doing the “extra” work—retesting, adjusting procedures, or communicating more openly than industry practice—but these habits keep our output relevant and trusted.

    Our facility regularly invests in updated analytical equipment and training. On any given week, team members review not just final product assessment, but in-process control charts, customer feedback forms, and regulatory bulletins. We owe much of our progress to this loop—production and innovation driven not by top-down mandates, but by real-world situations and customer outcomes.

    Conclusion: Why Choose (+)-Usniacin from a Direct Manufacturer?

    Selecting a raw material always brings an element of risk. By choosing a manufacturer who handles every detail of (+)-Usniacin’s journey—from building blocks to packaged shipment—customers gain an ally in their research, development, and production plans. Years of experience, reliable logistics, and documented analytical support ensure results match expectations. Problems, when they arise, have a direct path to solution.

    People come to us for quality, but they return for trust and peace of mind. In a market often filled with uncertainty, that reliability makes all the difference.