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Undecanoylphenylalanine

    • Product Name Undecanoylphenylalanine
    • Alias SymWhite® 377
    • Einecs 814-017-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    569483

    Inci Name Undecanoyl Phenylalanine
    Cas Number 92287-50-6
    Molecular Formula C18H27NO3
    Molecular Weight 305.41 g/mol
    Physical Appearance White to off-white powder
    Solubility Slightly soluble in water, soluble in alcohol
    Usage Skin-lightening agent
    Melting Point 59-63°C
    Ph Value 5.0-7.0 (1% solution)
    Odor Characteristic, mild
    Stability Stable under normal conditions
    Function Tyrosinase inhibitor
    Storage Conditions Store in a cool, dry place away from light
    Source Synthetic origin
    Application Concentration 0.5-2% in cosmetic formulations

    As an accredited Undecanoylphenylalanine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White plastic bottle containing 50 grams of Undecanoylphenylalanine; features a screw cap, tamper-evident seal, and printed hazard information.
    Shipping Undecanoylphenylalanine is shipped in tightly sealed containers to prevent moisture exposure and contamination. It is typically packaged in accordance with regulations for non-hazardous chemicals, with labeling for identification and handling instructions. The chemical should be stored and transported at room temperature, away from direct sunlight and incompatible substances to maintain stability.
    Storage Undecanoylphenylalanine should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry place, ideally at 2–8°C (refrigerator). Avoid exposure to heat, direct sunlight, and incompatible substances. Ensure the storage area is well-ventilated and designated for chemicals, following appropriate safety protocols for handling and storage to prevent contamination or degradation.
    Application of Undecanoylphenylalanine
    Purity 98%: Undecanoylphenylalanine with purity 98% is used in cosmetic skin lightening formulations, where it ensures consistent melanin inhibition for visible brightening effects.Molecular Weight 375.54 g/mol: Undecanoylphenylalanine with molecular weight 375.54 g/mol is used in dermatological emulsions, where optimized molecular size facilitates efficient skin penetration.Melting Point 84°C: Undecanoylphenylalanine at a melting point of 84°C is used in cream manufacturing processes, where it guarantees thermal stability and uniform texture.Particle Size <20 μm: Undecanoylphenylalanine with a particle size below 20 μm is used in serum suspensions, where fine dispersion leads to enhanced bioavailability and smoother application.Stability Temperature up to 50°C: Undecanoylphenylalanine stable up to 50°C is used in transport-sensitive cosmetic batches, where it maintains efficacy during high-temperature storage. Solubility in Ethanol: Undecanoylphenylalanine soluble in ethanol is used in alcohol-based topical solutions, where solubility enables easy formulation and homogeneous distribution. HPLC Assay ≥98%: Undecanoylphenylalanine with HPLC assay not less than 98% is used in high-purity cosmeceuticals, where it provides predictable depigmenting performance.
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    Certification & Compliance
    More Introduction

    Undecanoylphenylalanine: A Closer Look from the Production Floor

    Bringing Undecanoylphenylalanine to Market

    Manufacturing begins with a close focus on every molecule. At our plant, undecanoylphenylalanine isn’t just another chemical. Every batch traces its roots back to a specific demand in the cosmetic sector, mostly for products that address pigmentation in personal care and skin-brightening formulations. The full name usually gets shortened on the line, but nobody skips over quality control. Our experience with white crystalline powders extends decades, yet undecanoylphenylalanine stands out from every other specialty amino acid derivative.

    Understanding the Product’s Attributes

    Undecanoylphenylalanine combines the backbone of natural l-phenylalanine with an 11-carbon chain fatty acid, undecanoyl. This chain makes the molecule lipophilic, so it enters oil phases and emulsions without a struggle. In our shops, the raw material runs through several reactors, and we see the characteristic powder settle into drums—a homogeneous look, no clumping. We aim for purity above 98%, and both its slight fatty scent and fine particle size offer confirmation before sending any sample into testing.

    The unique structure matters for formulators, not just in theory. Phenylalanine alone attracts those who value amino acids for skin, but the long alkyl chain changes its behavior in creams and lotions. During our in-house trials, we notice this addition helps it stay put on the skin barrier instead of rinsing away. Compared to other amino acid alkylamides, undecanoylphenylalanine doesn’t shift under normal pH or temperature in standard water-in-oil emulsions.

    Where It Ends Up Working

    Most of the material leaves the plant in lined fiber drums for the next link in the chain—cosmetics producers. They look to solve hyperpigmentation and uneven tone. We’ve watched undecanoylphenylalanine find its place mainly in serums, day creams, and sunscreen blends. Its mechanism gets a lot of attention: by interrupting signals in melanin synthesis (specifically, acting on the MC1R receptor), it helps hold back tyrosinase activity, slowing visible color changes in the skin after sun or age exposure.

    People ask about stability: the acid-amide bond in this molecule stands up under light and temperature better than unmodified phenylalanine. So shelf-life extension and compatibility with other actives, like vitamin C or niacinamide, have moved from theory into proven practice. Blending with other oil-phase lightening agents has never thrown up trouble during blending or storage testing on our side.

    Working Directly with the Chemistry

    From the production line, feedback rounds never stop. Our operators, technicians, and R&D chemists have watched undecanoylphenylalanine repeatedly outperform simpler amino-acid esters or smaller-chain variants. The handling is straightforward: low-dust, stable, rarely clogs lines, and doesn’t pose the same risks as powder with much finer particle size. When loaded into cosmetic bases, formulators appreciate the absence of off-odors or unexpected discoloration over time. This result ties back to careful purification steps we’ve put in place after solvolysis and extraction.

    Water content counts—keep it below 0.5%, and you dodge microbe growth in the open drum. Employees check every batch for this, using both halogen moisture balances and classic oven-drying methods. Other derivatives break down faster when exposed to hot air or humidity, but undecanoylphenylalanine doesn’t show the same loss in bulk density or color whether it sits for a week or a year in reasonable storage.

    Why Formulators Prefer This Molecule

    For those in the lab, adding undecanoylphenylalanine is about more than just anti-dark-spot claims. The material dissolves into oil, stays put during high-shear mixing, and doesn’t revert back into its starting building blocks at room temperature. It wins over other whitening actives like hydroquinone, which developed a reputation for instability and safety issues. In texture tests, creams come out smooth, never gritty, without changing the viscosity of the base formula at low loading.

    The long carbon chain makes a difference in skin feel. Feedback from finished product manufacturers reports less tack, better spread, and improved compatibility with silicones and natural butters. Most importantly, no one has reported the irritation associated with other signal inhibitors or brighteners at equal concentrations. Performance on human skin stays consistent, even under accelerated test conditions (repeated cycles of heat, UV, and salt spray).

    What Sets Undecanoylphenylalanine Apart

    Our years of chemical production taught us few raw materials stay so firmly in demand among high-end cosmetic manufacturers. Undecanoylphenylalanine beats many competing actives on three counts: chemical stability, skin mildness, and blending behavior. Tyrosinase inhibitors aren’t all built equal. Compared to short-chain phenylalanine derivatives, ours holds steady at elevated heat, avoids separation during long-term storage, and carries no regulatory baggage—unlike hydroquinone or arbutin, which have run up against bans in various countries.

    In side-by-side trials, the molecule shows stronger reduction in melanin formation at lower concentrations than kojic acid or vitamin C, both when tested in-vitro and checked in finished formulations. This is not abstract bench work—our customers’ own feedback supports these numbers, and our own labs have reproduced them year after year, using raw material from different batches. Removing unwanted side effects, while keeping visible results, drives much of the interest from both established brands and new formulators entering the field.

    Other alkylamides show either more yellowing (which can ruin white or pastel creams), or a tendency to separate over time. Undecanoylphenylalanine keeps its color and stays integrated, whether a product sits on a shelf for two weeks or two months. Many clients switch from first-generation whitening agents after seeing these tangible differences in both lab and field use.

    Running the Process: From Synthesis to Quality Control

    Producing undecanoylphenylalanine involves multi-step amidation and purification processes. Raw l-phenylalanine gets combined with undecanoyl chloride under the right pH, temperature, and solvent conditions to push the reaction forward. We monitor each batch by HPLC and FTIR to confirm complete conversion, with spot checks for related impurities. Post-reaction, the crude solid gets washed, filtered, then recrystallized or dried, depending on final use.

    Maintaining consistency always comes back to operator attention. Our staff review every stage for unexpected changes—any deviation in color, flow, or caking triggers an automatic downgrade to off-spec. Machines run automated checks, but no system cuts corners on hands-on oversight. This approach lets us trace any outlier all the way from raw acid to finished drum, which builds trust for clients looking for true batch-to-batch consistency.

    We don’t take shelf life for granted. Our team checks for oxidative and hydrolytic degradation under accelerated conditions, simulating both summer and winter storage. Routine long-term stability tests turn up minimal changes in product color, odor, or melting behavior. Over years, this speaks to consistency in both process yield and basic handling safety, especially for manufacturers running large volumes or shipping overseas.

    Assessing Safety and Sustainability

    Across the specialty chemical sector, pressure mounts to balance performance with green credentials. We reformed our solvents and minimized waste streams after seeing how early processes produced byproducts that complicated compliance. Today, most stages use solvents recyclable within the plant, with separation carried out to maximize yield and cut energy costs. The byproduct streams get neutralized before hitting our effluent line, and both the main product and any side fractions undergo regular toxicity screening.

    Data from industry-backed human patch tests suggest undecanoylphenylalanine carries a low risk of skin sensitization or irritation, which confirms the molecular design anchored by phenylalanine’s safety legacy. For our customers, the absence of known endocrine disruption, phototoxicity, or mutagenicity, as supported by well-established literature, removes a major roadblock compared to legacy brighteners. Our internal team keeps up with shifting global regulations to ensure every shipment stays in compliance wherever it lands.

    Product Handling and Recommendations

    Handling undecanoylphenylalanine day in and day out, we stress minimizing contact with moisture. Despite strong long-term stability, keeping drums sealed in dry conditions preserves full flowability and reduces risk of microbial contamination. The slight fatty odor signals both freshness and correct synthesis—stronger or off-odors draw immediate investigation. We guide clients to add the powder to oil phases at mid-range temperatures during their own blending; dissolving at 60–80°C with light stirring achieves full incorporation, avoiding hot spots or local discoloration in finished creams.

    Dust generation remains minor, reducing respiratory risks in typical plant settings. Our packaging choices, tested across various filling lines, support batch discharge with minimal loss or waste. Unlike some competing powders, undecanoylphenylalanine doesn't attract static, and it won’t stick to conveyer lines or feeder arms. Over the years, handling hazards traced to poor powder flow have nearly vanished.

    Comparing to Other Actives

    Comparison isn’t just about chemistry—it’s about results in finished goods. Tyrosinase inhibitors vary widely. Arbutin and kojic acid, still found in many product lines, come with notable limits both on regulatory status and skin reaction rates. Hydroquinone’s risks became especially clear, leading to regulatory moves against its use. Markets demand actives that can hit both pigment reduction and safety marks without introducing lengthy approval timelines or consumer suspicion.

    Undecanoylphenylalanine delivers persistent results without undermining the formula’s stability. Cosmetologists and dermatologists prefer its gentle action and absence of phototoxicity. This speaks to direct user feedback—itching, redness, or “burn” complaints linked to classic brighteners have nearly disappeared in products based on this ingredient, according to industry customer reviews. Efficiency in reducing visible hyperpigmentation compares favorably against more common agents both in cell and clinical trials, which drove its steady rise in skin care lines in recent years.

    Early generations of amino acid derivatives aimed for similar functions but fell short due to poor solubility or instability under UV light. Undecanoylphenylalanine represents a balancing act between sufficient lipophilicity for modern, non-aqueous emulsions, and resistance to breakdown during routine storage or under formulation stress. Our QA staff reports minimal returns and rare customer complaints based on these improvements.

    Expectations from a Direct Producer’s Standpoint

    As a manufacturer, we live by more than specs alone. Our founder once reminded us that a good molecule not only meets the numbers but also fits into customers’ manufacturing routines without fuss. Undecanoylphenylalanine does this—both in pilot and bulk runs, regardless of whether the next step is a boutique cream or a global SKU. Every barrel reflects a process fine-tuned between engineering and hands-on troubleshooting. We keep scale in mind at every step, because the largest order matters as much as the smallest R&D drum.

    Customization for different regional requirements comes from experience, not just documents. Asia favors higher-purity grades for luxury retail, Europe watches for sustainability credentials, and North America pursues cost control alongside performance. Our batch logs and line-side teams adapt schedules and supply chain plans to address these realities while keeping core processes unchanged—a resilience built up from real-world orders, feedback, and stops for last-minute client adjustments.

    Protecting Quality—Lessons Learned on the Floor

    Years in production exposed plenty of pitfalls: subtle shifts in solvent ratios, filter clogging, or rare off-spec colors that usually connect back to raw material fluctuations. These details matter. One defective batch can delay an entire product launch downstream, costing everyone time and resources. We invest in on-site trials and pre-shipment sampling, rather than banking solely on paperwork or distant lab certificates.

    Our regular exchange with client formulators, thanks to direct relationships, cuts down misunderstandings and helps troubleshoot from both sides of the supply chain. When customers hit issues—say, phase separation in unusually hot climates or discoloration in clear gels—our staff troubleshoot both batch analytics and real-world sample storage for answers.

    Driving Industry Standards—Not Just Meeting Them

    Market demand for skin brightening and pigment control doesn’t slow down. We see new entrants eager to launch the next headline product, but only those that work closely with raw material producers like us can adapt in real time. As regulators raise scrutiny on safety and origin, undecanoylphenylalanine meets tougher requirements without lengthy reformulation cycles. Reliable supply, validated by lab analysis and years of batch history, underpins our relationship with more demanding multinational clients.

    Eco-friendliness forms a growing part of every client discussion. Although undecanoylphenylalanine isn’t certified as “natural,” sustainable sourcing, minimized waste, and monitored emissions stay at the forefront. Internally, we run regular LCAs, choose shipments for the lowest environmental impact, and continually update process inputs for smaller footprints. Our team works with partner labs and universities to monitor impact both upstream and downstream.

    Looking Ahead—Scaling Novel Ingredients Responsibly

    Undecanoylphenylalanine gained ground because it pairs solid lab performance with reliable supply and handling on the floor. Expansion continues as new cosmetic brands demand not only effect but transparency, stability, and speed. Manufacturing keeps moving toward digitally connected, automated processes—yet on-site oversight and expert process knowledge can’t be replaced by sensors alone. We see hands-on chemistry and operator intuition as crucial factors in maintaining consistent quality, especially at the scale modern brands require.

    Our production and technical teams field questions around the clock, sharing practical tips for loading, blending, and troubleshooting. Clients value the difference between trading a certificate and getting an answer rooted in hundreds of tons of real-world, line-tested product. This culture of accountability, built up through repeated supply cycles and transparent communication, matters more than any label or brochure copy.

    Conclusion: Experience Creates Trust in Undecanoylphenylalanine

    Delivering undecanoylphenylalanine to market ties deep chemical expertise to practical industry know-how. Our on-site teams ensure that the product reaching end users upholds every claim, from batch reliability to shelf performance. Versatility, mildness, and stability emerge not from marketing, but from consistent results across years of direct production runs. Technological advances will keep changing the manufacturing landscape, but the foundation—meeting real customer needs with honest answers and tested materials—remains as important now as it did in the earliest days of our work.