Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Sclareolide

    • Product Name Sclareolide
    • Alias Norambrein
    • Einecs 232-582-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    759158

    Chemical Name Sclareolide
    Cas Number 564-20-5
    Molecular Formula C16H26O2
    Molecular Weight 250.38 g/mol
    Appearance White to off-white crystalline powder
    Solubility Insoluble in water, soluble in ethanol and oils
    Melting Point 121-124°C
    Boiling Point 359.9°C at 760 mmHg
    Origin Natural sesquiterpene lactone derived from clary sage (Salvia sclarea)
    Usage Commonly used as a fragrance and flavoring agent

    As an accredited Sclareolide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Sclareolide, 25 grams, is packaged in a sealed amber glass bottle with a screw cap, labeled with product details and safety information.
    Shipping Sclareolide is shipped in tightly sealed containers, protected from light, moisture, and heat. Transport follows appropriate regulations for non-hazardous chemicals. Packages are clearly labeled, cushioned to prevent breakage, and shipped via approved carriers to ensure safe delivery. Documentation accompanies each shipment for tracking and regulatory compliance.
    Storage Sclareolide should be stored in a tightly sealed container, away from direct sunlight, heat, and moisture. It is best kept at room temperature, preferably in a cool, dry, well-ventilated area. Avoid sources of ignition and incompatible substances. Label the container clearly, and ensure storage compliance with local regulations for chemicals to maintain both safety and stability.
    Application of Sclareolide

    Purity 98%: Sclareolide with purity 98% is used in fragrance formulations, where enhanced olfactory intensity and consistency are achieved.

    Melting Point 121°C: Sclareolide with a melting point of 121°C is used in cosmetic creams, where thermal stability during production and storage is ensured.

    Particle Size <50 µm: Sclareolide with particle size less than 50 µm is used in nutraceutical tablets, where improved dissolution and bioavailability are obtained.

    Molecular Weight 256.41 g/mol: Sclareolide with a molecular weight of 256.41 g/mol is used in flavor encapsulation, where uniform compound incorporation is realized.

    Stability Temperature up to 80°C: Sclareolide stable up to 80°C is used in food additive manufacturing, where product integrity during pasteurization is maintained.

    Viscosity Grade Low: Sclareolide with low viscosity grade is used in liquid perfume bases, where easy formulation blending is facilitated.

    Assay HPLC ≥99%: Sclareolide with an assay HPLC of ≥99% is used in pharmaceutical intermediates, where high purity ensures consistent synthesis yield.

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    Certification & Compliance
    More Introduction

    Sclareolide: Nature-Derived Performance, From Raw Extraction to Industrial Impact

    Growing and Harvesting: A Commitment to Consistency

    Sclareolide heads out into the world from the humble beginnings of the clary sage plant. As the manufacturer, every year we track the shifting climate and variations in soil quality, from eastern fields in the early summer mist to the highland plots where the sun hammers down at harvest time. That long relationship with the fields means we recognize how rainfall, sun hours, and even the decisions our growers make each season influence the composition of the raw plant oils. The attention we give to each variable—planting dates, organic matter, irrigation timing—ultimately maintains the robust sclareolide content customers expect. Experience has shown us that heavy rains toward flowering will water down the extraction yields, while too much heat packs the resin with impurities. Constant monitoring and hands-on field management go a long way to assure the starting material never veers from ideal parameters.

    Extraction and Refinement: Technical Skill Directs Every Step

    Raw clary sage contains just a fraction of the eventual sclareolide. Turning that stem and leaf into a crisp, slightly woody solid means understanding everything from solvent ratios to distillation rates. In our facility, we keep control over steam temperatures and dwell times exact, calibrating each batch for the sclareolide molecule’s particular volatility. Deviating a handful of degrees in the vacuum distillation process turns an easy separation into a struggle with degraded side products. Centrifuge separators and chromatography columns require regular tweaking; running pure ethanol washes faster in cooler months ensures a soft, snow-white finish, but summer humidity tends to slow the evaporation step, affecting crystalline growth. Technicians do not rely on luck—they rely on historical batch data, and many years of trial and error that let them spot when filtration or cooling needs a shift in protocol.

    Purity, Color, and Physical Form: Standards Gained Through Effort

    Most buyers ask about purity up front. Our in-house sclareolide comes in at over 99% by HPLC, a figure we do not reach without aggressive small-batch testing and column fine-tuning. The white appearance of the end crystals comes from careful attention to washing and reprecipitation; any yellowing, even faint, signals early impurity pickup. From constant gain-loss records, we know that cut-corner processing near the end of a production run triggers microparticle carry-over, increasing bulk density beyond normal range, making the final product insufferably hard to dissolve. An experienced eye in the drying room means no guessing—a pure, powdery crystal slips easily through a gloved hand, while even a trace of excess solvent turns it sticky or clumpy. By taste and by smell—slightly amber-woody without bitterness—those with long tenure in the facility can pick up anomalies that never make it past the sensory panel.

    Model and Specification: What Sets Our Sclareolide Apart

    Clients recognize our sclareolide by model SCL-99, a designation tied to decades of validated runs. The SCL-99 model code means more than a paper guarantee; on the floor, it means exacting spectrometry matches, batch-to-batch. Moisture, particle size, melting point—these seem mundane compared to purity, yet they matter most to downstream users. Deep experience in crystal grinding makes for a consistent mesh size, never prone to clumping or segregation when customers are blending with other ingredients. Each shipment rolls out between 184–188°C melting range, fully dry, typically under 0.3% moisture. No ashed particles or oil residues slip through. That track record did not happen by chance but came from feedback loops with major international clients—compounders in fragrance and functional foods that shared real-world pain points. Early batches revealed that even a subtle shift in mesh size hampered solubility for encapsulators. Our process responded—milling steps slowed, laser diffraction instruments re-calibrated, and final particle size distributions tested in real application models, long before shipment.

    Application and End Use: What Real Users Demand

    Sclareolide finds a home in flavor, fragrance, and wellness industries. Over time, we have watched buyers' needs shift from mere volume to precise performance. The molecule itself, with its faint sweetness and musky depth, acts as a building block for perfume houses chasing stability at high dilutions. From direct conversations and factory visits, we understand that unreliable supply chains and unpredictable quality wreak havoc on large-scale formulations. Chemists in flavor houses look beyond theoretical yield and want to see robust thermal stability in their matrices—a must for concentrated essences held in storage for years. Supplement manufacturers bring up dissolving rates again and again: a coarser grade sticks to blending paddles and gums up blenders. By keeping particle sizes uniform and excluding fine dust, we’ve helped eliminate downtime at scale-up stages, a headache recounted to us many times by line managers in busy factories.

    How Our Sclareolide Stands Out

    The difference between our process and those used by smaller op shops or cheap resellers is hard-won. Sclareolide from alternative sources often turns up with off-notes: resinous, waxy, sometimes slightly sour undertones, usually traced to careless cuts in the extraction or mismanaged solvent recovery. Through GC-MS analyses and half a decade of client-side feedback, clear differences emerge—ours carries a singular purity signature, confirmed by third-party audits and direct re-testing at key client sites. We’ve found some parallel suppliers fudge drying times, or blend batches to fudge purity curves, leading to unpredictable losses at user sites. That’s not an option for our partners, who package for major consumer brands and face strict organoleptic and ISO compliance thresholds. We take our own sample libraries seriously: comparing freshly produced lots to two, five, and ten-year-old reference standards, updating them yearly to keep pace with evolving market scrutiny.

    Learning from Customers Large and Small

    Over the years, we’ve faced frank questions from ingredient buyers, from multinationals to innovative startups. Some demand detailed hazard analyses; others hone in on the subtleties of mouthfeel and aroma. Years ago, a perfumer flagged a powder batch that left a trace solvent odor in long-stored stock. That led directly to stricter ethanol stripping ratios and an updated drying chamber protocol. Another time, a supplement house reported slightly threadlike agglomerates in their finished capsules—an issue traced back to static buildup in the pneumatic conveyor system on hot, dry days, which required us to ground our bins and review humidity control. We take each piece of feedback seriously, as those lived realities shape the continuous tweaks to our methods.

    Physical Stability, Analytics, and Shelf Life

    Chemical stability determines a manufacturer’s true credibility. Each sclareolide lot undergoes forced aging studies—uncommon among peers, but invaluable to our assurance program. Accelerated tests under heat, light, and tropical humidity recreate worst-case warehouse conditions. From these, we record how bulk sclareolide resists caking, off-gassing, and color change. Stable at room temperature for two years, our crystalline sclareolide demonstrates little to no change in scent profile or moisture uptake, facts shared transparently with end users. Regular HPLC, GC, and FTIR audits ensure no broadening in impurity peaks, avoiding mystery degradants that can cause costly recalls. The rare red flag—a micro-impurity increase or early color fade—leads us to halt and reformulate on the spot.

    Sustainability and Transparency: Ethical Supply in Action

    Pressure mounts each year to avoid synthetic and petrochemical alternatives. We grow and source our clary sage according to strict sustainability standards, as documented by yearly audits from local agricultural boards. Fertilizer use drops year-on-year as we improve soil health naturally. Crop yields benefit from close rotation schedules while keeping wild pollinator populations intact. Residual waste from extraction cycles back as compost for the next harvest. By knowing our fields and workers personally, and keeping explicit records at the source, we cement credibility with international customers who face growing regulatory scrutiny under global ingredient sourcing standards.

    The Unique Challenge of Odor and Flavor Profile

    Unlike synthetics, natural sclareolide brings variability season to season. Slight modulations in aroma—warmer or more woody this year, a crisp tone the next—present a challenge but also underwrite authenticity. Through panel testing, both in-house and externally commissioned, we chart these subtleties and grade all material by both instrumental and human sensory panel. At large scale, even a tiny off-note noticed by a professional nose can spell costly delays; so every kilogram must earn approval from those who know what a proper woody-musky sweetness means for bottled bases, or how it will interact with citrus top notes in a perfume blend. Flavorists have pointed out many times that even marginal shifts in sclareolide purity or isomer ratios demand reformulation trials, adding to production costs downstream if inconsistencies creep in. These realities confirm for us that rigid adherence to origin, processing, and storage discipline keeps our product distinctive, never generic.

    Contaminants, Byproducts, and Compliance

    Many downstream users in food and fragrance sectors are under increased pressure to demonstrate ingredient traceability and contaminant-free status. Our own internal audits react swiftly to even small residue spikes—whether that’s solvent traces or naturally occurring crop byproducts. Advanced spectroscopy and residue analyses keep levels well below international regulatory cutoffs, protecting brand owners should surprise compliance checks occur. By funneling all upstream and midstream data into digital quality management systems, we spot deviations in real time. An “all clear” in the inspection record book isn’t an accident; it’s the result of multiple layers of testing and a zero-tolerance stance on out-of-spec product.

    Packaging, Handling, and Shipping Realities

    Chemical products, especially pure crystalline solids, demand careful shipping. Bulk sclareolide leaves our facility only in lined, sealed drums that stand up to humidity swings and transit delays. After an early episode where an improperly stored lot arrived clumped from moisture ingress, we refined packaging and added double-sealing protocols, a simple fix but one that made a marked difference for customers running automated dosing lines. Every drum ships under tamper-evident seals; each batch includes a full analytical record for on-receipt verification. Shipment logistics teams coordinate with both local and global couriers to prevent storage in uncontrolled warehouses, minimizing risk of quality drift before the product even arrives at user facilities.

    Future Developments and Ongoing Investments

    Market demand changes as new product applications emerge. Not long ago, we received repeated calls from synthetic biology firms looking to study minor sclareolide derivatives, far purer and cleaner than standard offering. That prompted investment into a pilot mini-refinery line inside our facility, offering ultra-high purity grades at micro-scale for research partners. Licensing and collaboration with botanical R&D institutes accelerates our innovation pace, so specialty grades for medical and cosmetic industries are already in the works. Keeping direct lines of communication with ingredient developers ensures we can anticipate and adapt to the next big application shift without sacrificing our well-established quality controls.

    Why Local Knowledge Trumps Generic Sourcing

    In the chemical world, a commodity can turn into a crisis when makers cut corners or disconnect from their own sources. Years in the sage fields and every shift at the extraction units have shown us where subtle errors creep in—a split-second lag during steam-off, or an unnoticed clump on a rainy loading dock. Sclareolide produced, packed, and documented through those daily, hands-on routines protects not only our own name, but keeps the larger industry running smooth and safe. Customers old and new tell us that what matters most is knowing there’s a human at the other end who’s seen the process, lived through missteps, and taken care to keep each lot right. The science matters, but so does the trust built from decade-long continuity.

    Dealing with Challenges, Providing Solutions

    The global supply chain presents problems—trade disruptions, growing certification requirements, and abrupt ingredient bans due to new regulatory findings. As a manufacturer who’s faced these hurdles, we know quick pivoting and honest communication with partners acts as the best shield. Should a crop year turn tough due to drought or pests, we are up front with allocation forecasts, never overselling or blending old stock to meet quotas. When a new contaminant threshold hits the books, our analytics team jumps in, benchmarking results against global standards, and updating protocols by the next batch cycle. If a customer faces a surprise at their line, open sharing of historical and RTU analyses allows for root cause analysis within hours, not weeks. In this industry, guesswork causes headaches; constant improvement, rooted in lived experience and technical rigor, saves time and reputation on both sides.

    Pride in Product, Responsibility to Customers

    Year in and year out, we stake our name on what leaves the facility. Sclareolide, at its best, represents not just plant-derived chemistry but a story of problem-solving in the face of evolving technical and regulatory demands. Our team’s expertise stands behind every drum and every kilogram—chemists, field managers, technicians, and long-term partners all feeding into a living, breathing process. Those relationships hold value when product launches hinge on the reliability of a single molecule, whose unique aroma and performance properties demand more than assembly line manufacturing. For us, sclareolide is more than an ingredient; it’s a test of every lesson learned, a commitment to pushing the highest standards, and an ongoing promise to those who build their own products from our source.