Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Osthole

    • Product Name Osthole
    • Alias 7-Methoxy-8-isopentenylcoumarin
    • Einecs 219-269-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    307855

    Chemical Name Osthole
    Molecular Formula C15H16O3
    Molecular Weight 244.29 g/mol
    Cas Number 484-12-8
    Appearance White to light yellow powder
    Melting Point 82-87°C
    Solubility Slightly soluble in water, soluble in ethanol and DMSO
    Source Naturally found in Cnidium monnieri and other plants
    Structure Type Coumarin derivative
    Purity Typically ≥98% (HPLC)
    Storage Conditions Cool, dry place, keep container tightly closed
    Boiling Point 384.6°C at 760 mmHg

    As an accredited Osthole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Osthole is typically packaged in a sealed, amber glass bottle containing 25 grams, labeled with product name, purity, and safety information.
    Shipping Osthole is typically shipped in tightly sealed containers to protect it from light, moisture, and air. Packaging complies with chemical safety regulations, using high-quality materials to prevent leaks or contamination. Transport is conducted via reliable courier or freight services, ensuring safe and timely delivery while maintaining product integrity and compliance with legal requirements.
    Storage Osthole should be stored in a tightly sealed container, away from light and moisture, at room temperature (approximately 20–25°C). It should be kept in a well-ventilated, dry area, distant from strong oxidizing agents and sources of ignition. Proper labeling and access restriction are recommended to ensure safety and stability, preventing contamination and degradation of the compound.
    Application of Osthole

    Purity 98%: Osthole with purity 98% is used in pharmaceutical formulations, where it enhances anti-inflammatory efficacy.

    Melting point 82°C: Osthole with a melting point of 82°C is used in topical ointments, where it ensures stable compound formation.

    Particle size 5 μm: Osthole with particle size 5 μm is used in dermal delivery systems, where it improves skin absorption rates.

    Stability temperature 40°C: Osthole with stability temperature 40°C is used in cosmetic emulsions, where it maintains bioactivity under elevated storage conditions.

    Extraction grade: Osthole of extraction grade is used in functional food additives, where it provides consistent antioxidant capacity.

    Assay ≥ 99%: Osthole with assay ≥ 99% is used in laboratory research, where it guarantees high reproducibility of pharmacological studies.

    Solubility in ethanol 50 mg/mL: Osthole with solubility in ethanol 50 mg/mL is used in injectable solutions, where it enables clear and homogenous preparations.

    Viscosity 20 cP at 25°C: Osthole with viscosity 20 cP at 25°C is used in liquid supplements, where it ensures uniform dispersion and optimal dosing.

    Residual solvent <0.1%: Osthole with residual solvent less than 0.1% is used in dietary supplements, where it minimizes impurity-related side effects.

    Optical rotation +30°: Osthole with optical rotation +30° is used in enantioselective synthesis, where it supports targeted chiral drug development.

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    Certification & Compliance
    More Introduction

    Osthole: Trusted Quality from a Dedicated Manufacturer

    Our Long-Term Focus on Osthole

    Osthole deserves every bit of the attention it receives in the herb extract market. Decades ago, our team recognized the need to improve consistency with coumarin derivatives. Getting Osthole pure, stable, and ready for production called for a deep investment in raw material sourcing and process development. Those early years taught us one simple truth: the result always reflects the care put in at the molecular level, long before shipment.

    We are proud to offer Osthole in crystalline powder form, with content ranging over 98% by HPLC, tailored for advanced food, pharmaceutical, cosmetic, and biotechnology applications. Other coumarins can fall short in terms of consistency or adaptability; Osthole sets itself apart by combining robust pharmacological potential with process-friendly chemistry. Through continuous research, our production has moved beyond basic bulk supply into a refined, tightly controlled workflow. By sticking to strict controls, and sourcing Cnidium monnieri from trusted farms, we keep batches consistent in appearance, solubility, and potency.

    From Plant to Product: Why Our Osthole Stands Out

    Our Osthole isn’t just a byproduct of convenience. Too often in this space, suppliers chase the lowest price or highest yield, overlooking structural impurities and seasonal inconsistencies. For us, each batch starts with sourcing Cnidium monnieri that meets rigorous traceability standards. We test each harvest for pesticides, heavy metals, and aflatoxins, discarding any material that doesn’t meet our safety targets. This reduces risks for downstream users in pharmaceuticals and high-value supplement manufacturing.

    Solvent extraction, purification, and recrystallization follow well-established SOPs in our facility. We track moisture, solvent residue, and particle size with almost obsessive attention. Our internal labs run spectroscopic and chromatographic analyses — not just on finished lots, but by stage. Resulting product comes as a fine, white crystalline powder, flowing easily, with consistent purity every time. Meeting global pharmacopeia standards isn’t just an afterthought for us, it’s embedded in our everyday tasks.

    Responsible Supply: Quality at Every Scale

    Scaling production of Osthole introduces new challenges — uneven plant batches, shifting extraction yields, and ever-evolving regulatory hurdles. We know from firsthand experience that skipping steps invites trouble. In the early years, we experimented with intermediate suppliers, but contamination crept in and analytical discrepancies became common. Pulling everything back under one roof made it easier to set expectations and monitor deviances. As a result, our Osthole has held up under independent audits and backward traceability requests from multinational clients.

    Some manufacturers cut corners to keep cost per kilogram low, but soon pay the price in unexpected recall risks or process shutdowns when impurities are found during downstream QC. We’ve helped several clients get back on track by analyzing problematic batches sourced elsewhere. In nearly every case, quality dropped due to shortcuts in growing, extraction, or handling. We invite our customers to visit and inspect production themselves, since transparency keeps everyone honest.

    Performance and Application Versatility

    Osthole’s unique profile makes it attractive for diverse industries. Pharmaceutical researchers pursue it for potential neuroprotective, anti-inflammatory, and vasodilatory effects. Cosmetic developers focus on its antioxidant and skin-conditioning potential. Animal feed and agriculture users see merit in pest resistance and plant growth effects. Its compatibility with different solvent systems and easy integration into both water- and oil-based formulations gives manufacturers a big advantage.

    We draw our confidence from real-world feedback. Our partners in plant pharmaceutical R&D praise the high stability of our stock when running long-term assays. Medical device teams have used our Osthole in prototype antimicrobial materials, noting reproducible results during accelerated aging tests. We work closely with them to adjust particle size and moisture targets as protocols evolve — always communicating any changes transparently. Cosmetic and supplement formulators appreciate our ability to deliver consistent organoleptic characteristics — color, flow, and minimal odor — achieving compliance with marketing claims and sensory panels.

    Comparing Osthole to Other Phytochemicals

    It’s important to correct misunderstandings about how Osthole compares to similar products. Many coumarin derivatives exist in nature, some sharing chemical roots or bioactivity overlaps. Imperatorin, xanthotoxin, and bergapten all get used for various purposes, but their extractability, solubility, and biological targets differ. Osthole stands out due to its favorable safety profile and multi-platform compatibility. Pure Osthole handles high-heat processing well and keeps stable across a wide pH range, unlike more volatile analogs.

    Analytically, Osthole’s distinct HPLC retention time and UV absorption features allow precise monitoring through multi-stage formulations. With less polar or volatile coumarin analogs, achieving this level of traceability becomes more difficult or expensive. Our chemists routinely troubleshoot with partners, comparing fingerprint spectra from production, making process adjustments before problems escalate.

    Ensuring Regulatory Compliance

    Navigating international regulatory requirements can be daunting without a dedicated in-house team. Our Osthole meets criteria for food safety (including limits for solvent residues and contaminants) demanded by food supplement and pharmaceutical ingredient regulations. We maintain records for each lot, storing test samples for potential reanalysis years after shipment. This practice allows us to swiftly address regulatory audits or customer concerns anywhere in the world.

    We don’t treat compliance as a paperwork exercise. Our staff undergo regular training to stay ahead of evolving standards in global markets. If a market tightens residue limits or updates labeling requirements, we adjust our methods and documentation. Our approach gives brand-owners and researchers confidence that their own regulatory submissions will withstand scrutiny.

    Transparent Relationships: Building Trust with Customers

    Direct conversations with users guide much of our decision-making. A research customer once pointed out small seasonal color differences in Osthole across successive orders. Taking that feedback seriously, we mapped batch color change and microtraced back to specific growing zones and climate conditions. Today, we coordinate planting windows and share incoming batch images with customers so expectations stay aligned.

    Another example came from a pharmaceutical pilot project that required extraordinarily low moisture content. Instead of just dehydrating in bulk and risking thermal degradation, we built out a dedicated low-temp finishing stage. This hands-on approach sets us apart from commodity suppliers who would treat every batch as identical. Access to decision-makers and knowledgeable staff makes the difference when projects move from trial to full-scale production.

    Industry Voices: Stories from the Field

    One large supplement brand turned to us after experiencing batch failures with a generic Osthole provider. They described tablets sticking together, odd scents, and variable dissolution in water. On closer review, most issues stemmed from high impurity levels and inconsistent moisture, factors directly influenced by upstream controls. With our input, the brand relaunched, seeing both improved product reviews and a lower return rate. Another client in cosmetics wanted to create a “natural actives” lotion line; our Osthole’s controlled plant traceability and clean analytics formed a standout story for their marketing team.

    We often share industry knowledge with our partners, helping small-scale formulators grasp regulatory changes or troubleshoot odd test results. Instead of pushing product, we focus on creating solutions that meet the user’s technical and business goals. Long-term relationships consistently lead to better outcomes for everyone — that’s been our experience.

    Challenges and Honest Solutions

    Every Osthole production run comes with its own set of challenges. Weather shifts can lower starting material content, loading more pressure onto purification and screening stages. Equipment upgrades sometimes require retraining or recalibration, neither of which can be rushed without risking batch failure. When a global solvent shortage hit, we qualified local replacements side by side, running parallel test batches instead of gambling on one approach. Our process improvement mindset helps us adapt without compromising safety or repeatability.

    We openly share batch analytics for independent review, recognizing that some customers require more stringent data for regulatory or quality reasons. In cases where lead time or batch size push the limits of a single facility, we partner with associated GMP workshops and cross-train technicians to keep standards aligned. If something slips, we own the problem and notify affected customers in real-time. This transparency builds mutual trust and keeps mistakes from repeating.

    Environmental Responsibility

    Responsible chemical manufacturing means more than meeting minimum regulatory marks. Environmental controls sit alongside our batch controls — we handle waste streams with strict adherence to local and international guidelines, reusing solvents where feasible, and minimizing water use at every stage. Our site teams monitor soil and water at growing sites, supporting plant suppliers with integrated pest management to avoid unnecessary chemical runoff. By paying attention to environmental impacts from field to finishing, we set ourselves up for long-term sustainability and community trust.

    We believe that ethical practices are as vital as chemistry — both for our business reputation and for everyone involved in the Osthole value chain. Staff training, third-party audits, and ongoing environmental impact studies form our daily practice, not just a checklist for annual review. Partners see this philosophy reflected in every shipment and every technical document we supply.

    Steering the Osthole Market Forward

    As Osthole gains traction in new therapeutic and technical fields, the need for secure, well-documented supply only grows. Research demand often outpaces guidance, so we invest in up-to-date analytics and new application studies. Collaborating with technical institutes and regulatory agencies allows us to update protocols and anticipate new uses before regulations change. By being proactive, we give customers an edge — and stay flexible as project requirements evolve.

    We welcome input from our users, sharing learnings so new entrants avoid common pitfalls. The fastest-growing partners are those who value transparency over short-term savings. Time and again, sharing source details, processing methods, and analytics allows marketing teams, R&D leads, and procurement professionals to make confident, informed decisions.

    Industry Partnerships and Ongoing Improvements

    Our longstanding relationships with agricultural partners keep supply chains agile. We coordinate growers throughout the cycle, offering up-to-date soil and crop management guidance. By understanding plant physiology intimately, we help secure robust starting material — the backbone of high-purity Osthole. On the facility end, ongoing lab upgrades and automation enable us to avoid common bottlenecks as customer orders scale up.

    We keep our production teams informed about the latest in extraction technology and analytical science. Internal roundtable meetings tackle persistent quality drift issues, with input from front-line operators and QA staff. This balanced, hands-on approach gives us early warning signs of any process drift, protecting lot quality and customer timelines.

    Beyond the Factory: Supporting Research and Innovation

    We do more than just deliver finished product. By participating in cooperative research and supporting publications in scientific conferences, our Osthole chemistry teams expand the boundaries of application every year. We’ve supported hospitals, universities, and private labs exploring Osthole use in fields from anti-inflammation and neurological protection to agricultural biostimulation. We supply not only bulk production lots, but also test-scale orders and tailored packages for early-phase research groups.

    Our experience helps nascent research programs bypass early formulation headaches. By offering insight from the manufacturing side, we help researchers optimize extraction, handling, and testing protocols. Combined with our practical guidance, users see better data quality and faster time to publication — amplifying discovery in every field Osthole touches.

    Looking Ahead

    Osthole remains a growing market, with new applications likely in the years ahead. Trustworthy sourcing, validated process controls, and transparent partnership will define the leaders in this space. For us as a manufacturer, every batch reflects years of learning and a hands-on approach. Our customers benefit from that commitment — in both product quality and peace of mind. For technical teams, quality control leads, purchasing managers and R&D specialists seeking a reliable partner in Osthole, we bring not just product, but a proven process and an open door for collaboration.