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HS Code |
882381 |
| Product Name | Liquiritoside |
| Chemical Formula | C21H22O9 |
| Molecular Weight | 418.40 g/mol |
| Cas Number | 31616-13-2 |
| Appearance | Yellow to brown powder |
| Solubility | Soluble in water and ethanol |
| Storage Conditions | Store in a cool, dry place away from light |
| Purity | ≥98% (HPLC) |
| Source | Extracted from Glycyrrhiza uralensis (licorice root) |
| Application | Used in pharmaceuticals and nutraceuticals |
| Melting Point | 210-215°C |
| Synonyms | Liquiritin apioside |
As an accredited Liquiritoside factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Liquiritoside is packaged in a 1g amber glass vial, sealed for protection against light and moisture, and clearly labeled. |
| Shipping | Liquiritoside is shipped in tightly sealed containers, protected from light, moisture, and heat. It is handled according to standard chemical safety protocols, ensuring secure packaging to prevent leakage or contamination. Shipping complies with local and international regulations for research chemicals, and delivery typically occurs via reputable, licensed chemical courier services. |
| Storage | Liquiritoside should be stored in a tightly sealed container, protected from light and moisture, at a temperature of 2-8°C (refrigerated conditions). Avoid exposure to air and high humidity to prevent degradation. Store in a well-ventilated area, away from incompatible substances such as strong oxidizing agents. Properly label the container and ensure that only trained personnel handle the chemical. |
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Purity 98%: Liquiritoside Purity 98% is used in pharmaceutical formulation development, where it ensures consistent pharmacological efficacy in tablet production. Molecular weight 418.39 g/mol: Liquiritoside Molecular weight 418.39 g/mol is used in nutraceutical ingredient blending, where it facilitates precise dosage control for supplement standardization. Melting point 170°C: Liquiritoside Melting point 170°C is used in solid dispersion manufacturing, where it enables improved thermal stability during processing. Particle size D90 < 20 µm: Liquiritoside Particle size D90 < 20 µm is used in topical dermatological applications, where it allows enhanced skin absorption and uniform texture. Stability temperature up to 60°C: Liquiritoside Stability temperature up to 60°C is used in beverage fortification processes, where it maintains antioxidant activity under pasteurization conditions. Water solubility 20 mg/mL: Liquiritoside Water solubility 20 mg/mL is used in liquid oral suspensions, where it secures rapid and homogeneous mixing for bioavailability. UV absorbance λmax 275 nm: Liquiritoside UV absorbance λmax 275 nm is used in analytical quality control, where it enables accurate quantification during high-performance liquid chromatography assays. Residual solvent < 0.5%: Liquiritoside Residual solvent < 0.5% is used in botanical extract standardization, where it ensures compliance with regulatory safety thresholds. Ash content < 0.1%: Liquiritoside Ash content < 0.1% is used in health food powder formulation, where it contributes to product purity and minimizes contamination. pH stability 4–8: Liquiritoside pH stability 4–8 is used in beverage enrichment applications, where it preserves active integrity across common acidic and neutral drink matrices. |
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Our expertise in producing Liquiritoside stems from years of hands-on process refinement and real-world collaboration with researchers and downstream formulators. Liquiritoside, recognized in the industry for its distinctive flavonoid profile sourced from licorice root, represents a cornerstone for many applications in health, cosmetic, and biotechnology fields. In our manufacturing environment, quality is shaped not just by meeting benchmarks but by a continuous push toward process control, traceability, and customer feedback.
On our site, Liquiritoside is produced in batches to guarantee batch-to-batch consistency. We run HPLC analysis on each lot, making sure purity for our common specification exceeds 98%. The product carries a molecular structure that distinguishes it from glycyrrhizin or liquiritin, which are commonly referenced as licorice constituents. Our model for Liquiritoside, which customers often identify under our in-house code LQS-98, is standardized for particle size and moisture content. Typical lots show water content below 0.5% and exhibit visually a pale yellow to light brown powder. These parameters matter because the industries we serve rely on downstream processes such as blending, granulation, or encapsulation where subtle variations cause significant changes in outcome.
Our approach to Liquiritoside stretches from raw material gathering to environmental stewardship in waste management. We work with contracted licorice farmers respecting seasonal fluctuations and soil health. These upstream steps influence the extract’s profile. Solvent-extraction runs follow containment protocols and documentation checks so both our safety and purity profiles stay intact throughout the refinery.
Customers in the nutraceutical sector, especially those focusing on anti-inflammatory and antioxidant functional products, have noted that Liquiritoside outperforms more common licorice extracts when they look for targeted flavonoid benefits with fewer side effects tied to glycyrrhizin. Formulators for dermal creams, oral tablets, and beverage supplements report improved sensory and stability profiles with our Liquiritoside compared to other licorice derivatives. The consistency of appearance and the absence of strong odor simplifies downstream processing and supports cleaner labeling for consumer-facing brands.
While the world of licorice-derived ingredients features glycyrrhizin, liquiritin, and various polyphenols, Liquiritoside covers a rare niche. Chemically, it does not mimic the saponin-like sweetness of glycyrrhizin nor share the solubility limitations seen in many crude licorice powders. Our process controls headline the difference: instead of a solvent-heavy extraction followed by minimal purification, we employ membrane separation and multiple recrystallization steps. This practice not only shrinks the off-flavors but also shields active sites from degradation.
Most traders or third-party suppliers offer generalized licorice extracts with poorly defined compositions. A direct line to manufacturing eliminates guesswork. Any change in root origin, seasonal batch, or process step is documented and can be traced directly to the finished powder, something our clients regularly verify during audits. Our technical team interacts directly with clients’ R&D for process matching from an early stage, offering a confidence level that speculative brokers can rarely match.
Liquiritoside production demands vigilance throughout each operation on our plant floor. The raw licorice root presents noticeable fluctuations in active compound ratios based on geography, rainfall, and even microclimate. We inspect every incoming lot, measuring active compound levels and soil residues, before green-lighting the batches for extraction.
Solvent selection involves more than just maximizing yield. Downstream customers require low residual levels. We undergo quarterly audits and continually update our protocols to work towards more sustainable solvents and closed systems. The repeated purifications minimize contaminants and produce a powder with clear analytical fingerprints.
The last step, drying, sets the solubility and shelf life. Any shortcuts here degrade the product or lead to clumping, which complicates further handling. Years of production have led us to select specific vacuum drying conditions—balancing temperature to preserve actives while driving off residual humidity.
Our records extend from the field to the packaging plant. Each drum of Liquiritoside carries batch-level traceability down to the date and location of licorice root harvest. On request, we provide full analytical breakdowns—showing fingerprints for related flavonoids, heavy metals, and residual solvents. These reports form the backbone for regulatory submissions across Europe, North America, and Asia.
Through years of direct customer engagement, several usage patterns with Liquiritoside have proved reliable. Manufacturers blending Liquiritoside into tablets favor its dry-flow properties. Cosmeceutical brands enjoy its neutral profile, which integrates cleanly into creams or gels without color migration or strong olfactory notes. Beverage and functional food producers use it for its mild sweetness and active flavonoid benefits, complementing other bioactives without risk of acrid off-tastes.
Clients who have shifted from conventional licorice extract to Liquiritoside note a significant improvement in formulation stability. In finished skincare products, Liquiritoside’s profile enables better texture and improved shelf integrity. Pharmaceutical developers focusing on botanically active drugs benefit from the reproducibility inherent in our tightly controlled processes.
The licorice trade faces volatility because of weather, export regulations, and changes in wild harvest practices. Relying on trusted, contracted farmers, with yearly quality audits and multi-year relationship-building, buffers us from price spikes and scarcity. This stability passes on to our clients: fewer disruptions, consistent pricing, and assurances of purity.
Transparency counters much of the speculative uncertainty found in third-party supply. By controlling the entire production chain, we prevent counterfeit or adulterated batches from ever reaching the outside world. Customers regularly visit our facility, observe the entire process, and certify their own standards against ours.
Scaling up a plant-derived active is not trivial. The leap from bench chemistry to full production introduces challenges—variability, cost, and regulatory complexity. We have invested in modular plant design, letting us ramp capacity or pivot volumes based on seasonal demand. Through scalable processes, we protect both quality and availability whether shipping kilograms or metric tons.
Batch reports and process logs confirm to our clients that what leaves our doors reflects their prior approvals and matches the formulations they have tested. Continuous feedback loops from global partners improve our internal controls each year, so our production line delivers where both startups and established brands need reliability.
Purity claims in botanical extracts can easily mislead if taken in isolation. Through repeated audits, both internal and regulatory, we refine not just what’s measured by HPLC but monitor impurities from solvent residues, heavy metals, and agricultural byproducts. Real purity results from industrial discipline: thorough raw material checks, in-process sieving and filtration, multiple chromatographic steps, and detailed recordkeeping. Our production team sees the results directly in smoother processing and cleaner separation during subsequent use by our downstream partners.
Supply chains around natural ingredients now face tighter controls and evolving health standards. Updates in European and Asian regulations have prompted annual reviews and refits of our standard operating procedures. We have adopted more stringent batch certification and continue to push for non-toxic solvents and greener extraction conditions. Regular engagement with regulatory bodies speeds approval cycles for our customers, helping reduce time to market. Our commitment to documentation, traceability, and compliance means every unit of Liquiritoside ships with fully transparent credentials.
An open line from factory to customer eliminates information gaps. The feedback we gather from technical teams, pharmacists, and industrial users shapes our ongoing improvements. Clients trust that every lot of Liquiritoside meets the specifications discussed—not what someone else claims, but what both parties have seen perform in the real world.
We resist the temptation to push batches that fall outside specification into the market, even at a financial loss. Instead, we reprocess or blend back into controlled runs, maintaining the integrity of our product and the reputations of our clients. This standard pushes us to constantly improve our control of both yield and purity.
Success in producing Liquiritoside goes beyond the equipment. Our team handles raw materials, tracks batches, and watches for process drift. We keep records stretching back more than a decade, which allows identification of potential weak points before they cause serious problems. Sharing this knowledge across teams means any issue in blending, extraction, or packaging is solved and documented for reference. This culture of learning translates into consistently better product each cycle.
Those looking for Liquiritoside have choices. Working directly with an established manufacturer fosters benefits no broker or casual supplier replicates. Predictability, transparency, and a rich experience in troubleshooting formulation challenges empowers brands to grow and adapt without costly delays. Years of practice smoothing out the production kinks, managing the unpredictable quirks of raw licorice, and sharpening our analytical verification have built a product that is reliable on the production line and trusted in the lab.
Customers facing sudden shifts in product specification, unexplained impurities, or delayed shipments often trace these problems to loosely coordinated supply arrangements or intermediaries with incomplete product knowledge. Dealing directly with the producer narrows the knowledge gap and clears decision paths for regulatory issues and future development.
Our product development is ongoing. Working with research institutions and industrial partners, we’re exploring enhanced extraction pathways, new applications for high-purity liquiritoside, and integration with sustainable methods. Early-stage projects include microencapsulated forms for beverage applications and synergistic blends with other botanicals for targeted nutraceutical purposes. Sharing advances and failures alike helps the broader community make informed decisions, raising the industry standard each step of the way.
Longevity in the manufacture of Liquiritoside brings with it an understanding of the constraints and opportunities involved in natural product supply chains. The difference between a product that simply tests within range and one that works reliably over hundreds of thousands of units lies in the discipline of daily practice. Through continuous monitoring, supplier partnerships, and willingness to adapt as regulations shift, our team keeps Liquiritoside ready for a range of innovative applications. Above all, the trust of those who use the compound in formulations, trials, and finished goods validates this approach and encourages us to keep refining what we do.