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HS Code |
195455 |
| Name | L-Epicatechin |
| Chemical Formula | C15H14O6 |
| Molecular Weight | 290.27 g/mol |
| Cas Number | 490-46-0 |
| Appearance | White to off-white powder |
| Solubility | Soluble in water and ethanol |
| Melting Point | 240-242°C |
| Purity | Typically >98% |
| Source | Found naturally in cocoa, tea, and some fruits |
| Storage Temperature | 2-8°C |
| Usage | Dietary supplement or research ingredient |
| Synonyms | (-)-Epicatechin, L-Epicatechol |
| Stability | Stable under recommended storage conditions |
| Odor | Odorless |
| Ph Range | Neutral in solution |
As an accredited L-Epicatechin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | L-Epicatechin is packaged in a sealed, amber glass bottle containing 25 grams, labeled with product details, safety, and storage instructions. |
| Shipping | L-Epicatechin is typically shipped in tightly sealed containers, protected from light and moisture, to preserve its stability. It is handled as a non-hazardous chemical, but should be transported according to standard chemical safety protocols. Shipping includes proper labeling and documentation in compliance with local and international regulations. |
| Storage | L-Epicatechin should be stored in a tightly sealed container, protected from light and moisture, and kept in a cool, dry place—ideally at 2–8°C (refrigerated). Avoid exposure to air and extreme temperatures to prevent oxidation and degradation. Proper storage ensures the chemical’s stability and extends its shelf life for research or industrial use. |
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Purity 98%: L-Epicatechin Purity 98% is used in nutraceutical formulations, where it supports enhanced antioxidant activity in cellular assays. Molecular Weight 290.27 g/mol: L-Epicatechin Molecular Weight 290.27 g/mol is used in cosmetic serums, where it provides efficient free radical scavenging for skin health. Melting Point 238-240°C: L-Epicatechin Melting Point 238-240°C is used in controlled pharmaceutical synthesis, where it assures product consistency during compounding. Particle Size <10 µm: L-Epicatechin Particle Size <10 µm is used in food supplement premixes, where it ensures homogeneous blending and uniform dispersibility. Stability Temperature Up to 55°C: L-Epicatechin Stability Temperature Up to 55°C is used in beverage enrichment, where it maintains bioactivity after pasteurization. Solubility in Ethanol 50 mg/mL: L-Epicatechin Solubility in Ethanol 50 mg/mL is used in botanical extract formulations, where it offers superior dissolution and bioavailability. Optical Rotation [α]D20 +80° to +90°: L-Epicatechin Optical Rotation [α]D20 +80° to +90° is used in enantiomerically pure active pharmaceutical ingredient (API) production, where it delivers verified stereoisomer specificity. Residual Solvent <0.5%: L-Epicatechin Residual Solvent <0.5% is used in regulatory-compliant dietary supplements, where it guarantees consumer product safety. Ash Content <0.2%: L-Epicatechin Ash Content <0.2% is used in analytical standard preparations, where it minimizes interference in spectrometric measurements. Moisture Content <1.0%: L-Epicatechin Moisture Content <1.0% is used in polymer blend applications, where it reduces the risk of hydrolytic degradation during processing. |
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After years spent in the chemical manufacturing space, a compound like L-Epicatechin stands out for its versatility and solid scientific track record. We handle everything in-house, from extraction to purification to final quality checks, and along the way, we have gained a close-up understanding of what this plant-derived compound can do.
Much of the demand for L-Epicatechin comes from customers who require high purity and batch stability. We focus on standardized, reproducible product quality, offering L-Epicatechin (CAS Number: 490-46-0) with a purity above 98%. Each kilogram is a fine, off-white to light brown powder depending on the batch and raw material origin, carefully packaged to prevent oxidation and moisture exposure. Particle size usually falls between 80 and 120 mesh, a spectrum chosen based on feedback from food and supplement producers who require easy incorporation into liquids or solids. Moisture content typically remains below 2%, and our microbial and heavy metal checks are rigorous, supporting use in both food and nutraceutical applications.
Low-grade or adulterated extracts can present real risks. Years ago, even small deviations in source quality led to loss of color or shift in solubility, which caused significant issues in downstream formulations. We've responded by building direct supply chains with well-established plantation owners, controlling harvest timing, and refining solvent extraction parameters. Our technical teams keep meticulous batch records, keeping the compound’s origin, grade, and lab analysis transparent. Customers ask about our verification procedures during audits, and we show not only HPLC chromatograms but historical traceability for up to three years. This attention to traceability means you’re not getting guesswork or shortcuts.
Our clients use L-Epicatechin mostly in dietary supplements, functional beverages, cosmetics, and specialized pharmaceutical formulations. As a polyphenol, its appeal rests on its strong association with support for cardiovascular health, cognitive function, and athletic recovery. Teams in supplement development talk with us about dose ranges and stability testing, since polyphenols can lose activity if exposed to light, heat, or air. We have learned from early pilot runs that microencapsulation, co-processing with certain preservatives, or working at low temperatures in food-grade environments produces the best long-term results.
We’ve encountered a surge in interest for catechins in general due to the explosion of green tea extracts on the market. Unlike generic green tea polyphenols, L-Epicatechin stands apart as a single, well-characterized molecule. Its isomeric purity allows more consistent formulation and dosing. Many competitors sell bulk blends that mix catechins, caffeine, and even unrelated tannins—these blends dilute potency and make it difficult to guarantee label claims.
From a raw material point of view, sourcing only from established cacao and certain tea cultivars means a more predictable supply and fewer batch-to-batch surprises. This differs from companies who rely on wildcrafting or broadly defined tea-leaf extracts, which often result in unstable product quality and varying health effects. Some customers have told us about past experiences with poorly characterized catechin products that clumped in their machines or produced inconsistent analyses in their own labs—issues we solve with strict lot validation and in-house technical support.
Moving from bench-scale extraction to tonne-level batches brings challenges few outside our field appreciate. L-Epicatechin responds poorly to prolonged exposure to heat and air, often oxidizing and darkening when handled carelessly. Our facility design keeps all processes under nitrogen, minimizing oxygen contact. Solvent selection is critical; ethanol and water extraction at controlled pH preserves the highest ratio of active L-Epicatechin, and rapid filtration shortens processing time.
Waste management rises in importance at scale. Polyphenolic byproducts can quickly overwhelm waste treatment systems if process water isn’t properly conditioned. Years back, equipment scale-up introduced unexpected fouling, driving us to optimize pressure, flow rates, and filter media. Close monitoring during purification prevents product degradation as well as regulatory violations. Each improvement translates into more reliable outcomes for customers and easier compliance during third-party audits.
Interest in polyphenols continues to rise as consumers pursue more natural antioxidants. Demand swings have hit other catechins harder, but L-Epicatechin remains a staple with wellness companies and cosmetic formulators. Some countries keep regulatory lists for positive and negative use of botanical extracts in supplements and personal care items. As a manufacturer, we work directly with consultants on regulatory compliance. This means reviewing not just compositional analysis but labeling, allergen statements, and maximum allowable daily intakes based on national and international guidelines.
In practical terms, staying ahead involves regular review of scientific literature and keeping communication open with clients, who update us when their regulatory or documentation needs change. Certifications—like GMP and ISO 22000—are part of daily production rather than a one-time milestone. We receive periodic spot checks from customers’ auditors as well, and never put batch release ahead of proper documentation.
Nutritional companies design their drink mixes and capsules around purity, taste, and dispersibility. L-Epicatechin at high purity provides a mild, slightly astringent flavor and integrates seamlessly into powders or emulsions. Through years of feedback, low-dust, free-flowing powders became a focus for us, as earlier grades caused caking or inconsistent blending. Consistent spectra and low odor content receive positive notes in client surveys.
Cosmetic chemists choose L-Epicatechin because of its strong antioxidant performance and gentleness on skin. We conduct stress stability testing under accelerated light and temperature conditions, sharing results with our partners for inclusion in their dossiers. Pharmaceutical partners working on botanical actives have engaged us to run extended impurity profiling, ensuring compliance with even the tightest finished-product standards. A product that performs in technical and sensory trials means repeat orders and longer collaborations—our staff see this firsthand with each new formulation challenge.
Our relationship with growers evolves along with our sourcing reality. Plant diseases, environmental changes, and labor disruptions have pushed us to diversify both geographical origin and cultivar selection. Each switch introduces its own challenges, especially as minor alterations in raw material can modify the final product’s taste and color. Traceable, documented supply chains keep recall risk low and let us address customer questions on sustainability and ethics.
Direct contracts with growers and investment in perennial cultivars produced marked improvements in both yield and processing quality. Regular agronomy visits and harvest training sessions with suppliers ensure consistency. Our technical staff test pilot batches during harvest seasons to confirm specifications are met before releasing for industrial-scale processing.
Open technical exchange with clients has taught us how important detail and transparency are. Food developers often request detailed certificates tracing contaminants down to the parts per billion. Supplement companies present formulation challenges involving complex blends. Each time, our technical and R&D teams cooperate across teams to design custom solutions within the boundaries of natural ingredient supply and regulatory structure.
Years ago, a customer requested an L-Epicatechin variant optimized for "off-taste masking" in a new sports drink line. We devoted resources to granulation and blending research, iteratively modifying particle size distribution and surface area until the sensory panel reported a significant decrease in bitterness. In skin-care, emphasis on low residual solvents changed our drying method from high-temperature vacuum to a gentler, stepwise dehydration process, introducing a product line with even lower residuals for sensitive formulations.
Staying ahead means constant vigilance about adulteration, especially as demand rises in the nutraceutical market. Polyphenol content alone isn’t enough—accurate, repeated assays of enantiomeric purity and contaminants are needed. We operate both in-house testing and validated outsourcing with independent labs, matching techniques such as chiral HPLC and LC-MS to customer product standards.
As customers request higher transparency, questions arise on carrier materials and anti-caking agents. Some are wary of silicon dioxide or maltodextrin; we have worked on "clean label" alternatives by carefully adjusting drying times, granule shape, and storage conditions so the product remains free-flowing. Direct client feedback led us to phase out certain carriers entirely and run ongoing storage condition trials across humidities and temperatures.
Greater understanding of L-Epicatechin’s effects and improved detection methods have shaped how we work. Academic groups helped clarify ideal storage conditions, routes of degradation, and rate constants for oxidative breakdown. This partnership means faster, more targeted improvements at the reactor, storage, and dispatch stage. We share peer-reviewed evidence with customers who require it for registration or marketing purposes, and every validated improvement finds its way into SOPs.
Not all molecules can show such range—L-Epicatechin serves small research houses as well as international firms. Our experience serving different customer scales led us to implement batch reservation and graded lot sizing. Some contract manufacturers order only grams per month for R&D, and others request tonnes for multi-country launches. We match the packaging and documentation load to order scale, streamlining export and customs procedures.
Environmental stewardship influences each processing choice. Polyphenol-rich process water undergoes thorough treatment before discharge, and byproduct solids feed into local composting programs or, in some regions, as animal feed supplements. We monitor emissions and effluents against regional government guidelines and keep records open to customer inspection.
Supporting the workforce at the source affects long-term business stability. We commit to honest labor practices, regular supplier audits, and transparent payment models with plantations. This reduces turnover and motivates growers to maintain quality. Each batch of L-Epicatechin carries a story from seed to shipment, and customers who visit our facilities see the direct connection between ethical choices and the finished product.
There is no single formula for building the best L-Epicatechin supply, but cumulative effort—scientific vigilance, honest trade relations, and continuous feedback—brings the strongest results. Over years of manufacturing, every batch, every technical challenge, every customer request adds to what we know. We’re always open to sharing and adapting methods so clients receive solutions that work for their specific application.
As L-Epicatechin earns more attention in science and consumer markets, production methods and supply structures will undergo constant review. We invest in lab upgrades, staff training, and process resilience. Every product departure, whether by courier, cargo, or direct transfer, carries months of work and care. We recognize the trust customers place in raw material suppliers, and we meet this trust with vigilance, technical support, and adaptability.