Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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L-Citrulline

    • Product Name L-Citrulline
    • Alias l-citrulline
    • Einecs 206-759-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    529401

    Chemical Formula C6H13N3O3
    Molecular Weight 175.19 g/mol
    Appearance White crystalline powder
    Solubility In Water Freely soluble
    Melting Point 214–216°C (417–421°F)
    Pka 1.76
    Cas Number 372-75-8
    Iupac Name (S)-2-amino-5-ureidopentanoic acid
    Taste Slightly sweet
    Source Naturally found in watermelon
    Usage Dietary supplement
    Storage Conditions Store in a cool, dry place
    Stability Stable under normal conditions
    Odor Odorless
    Bioavailability High when taken orally

    As an accredited L-Citrulline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White resealable pouch labeled "L-Citrulline, 500g" with blue accents, purity information, supplement facts, and manufacturer details displayed.
    Shipping L-Citrulline is typically shipped in sealed, moisture-proof containers to prevent contamination and degradation. It should be stored in a cool, dry place, protected from light and heat. During transport, care is taken to avoid exposure to extreme temperatures or humidity to ensure product quality and stability upon delivery.
    Storage L-Citrulline should be stored in a tightly sealed container, protected from moisture, heat, and direct sunlight. Keep it in a cool, dry, well-ventilated area, ideally at room temperature (15–25°C). Ensure that the storage area is free from incompatible substances such as strong oxidizers. Proper labeling and secure storage are recommended to prevent contamination and accidental misuse.
    Application of L-Citrulline

    Purity 99%: L-Citrulline Purity 99% is used in sports nutrition supplements, where it enhances nitric oxide production and improves exercise endurance.

    Micronized Particle Size: L-Citrulline Micronized Particle Size is used in pre-workout formulations, where it increases solubility and accelerates absorption rates.

    Stability Temperature 60°C: L-Citrulline Stability Temperature 60°C is used in functional beverages, where it maintains bioactivity during pasteurization processes.

    USP Grade: L-Citrulline USP Grade is used in pharmaceutical preparations, where it ensures compliance with safety and efficacy standards.

    Moisture Content <1%: L-Citrulline Moisture Content <1% is used in effervescent tablets, where it prevents caking and preserves dispersibility.

    Odorless Form: L-Citrulline Odorless Form is used in flavored drink mixes, where it allows unobstructed sensory profiles.

    Free-flowing Powder: L-Citrulline Free-flowing Powder is used in automated capsule-filling operations, where it improves processing efficiency and dosage uniformity.

    Assay ≥98%: L-Citrulline Assay ≥98% is used in clinical nutrition products, where it guarantees therapeutic consistency and potency.

    Melting Point 214°C: L-Citrulline Melting Point 214°C is used in health food bars, where it provides thermal stability during manufacturing.

    Low Heavy Metal Content: L-Citrulline Low Heavy Metal Content is used in medical dietary supplements, where it ensures safe long-term consumption.

    Free Quote

    Competitive L-Citrulline prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

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    Certification & Compliance
    More Introduction

    L-Citrulline: Quality Craftsmanship from the Manufacturer’s Perspective

    What L-Citrulline Means to Us

    In the chemical industry, the way a product is made and handled speaks for itself. L-Citrulline isn’t just a chemical for us. It carries years of accumulated industry know-how, stubborn quality-mindedness, and a practical understanding of what partners look for in a reliable ingredient. What matters most is making each batch with consistent purity, easy solubility, and trouble-free performance in production processes. Because we’re on the factory floor, not just in a showroom, we see firsthand what L-Citrulline must bring to the table and what challenges a subpar product can create.

    From Raw Material to Finished L-Citrulline

    Production starts with high-grade sources. Every shipment of raw materials goes through strict selection before synthesis to curb contamination. This attitude shows up throughout our supply line, from our deep reliance on regular audits of suppliers to the care we put into storage. The fermentation and purification steps are central. If shortcuts or guesswork seep in during crystallization, residue or off-notes in the finished L-Citrulline can lead to customer complaints and wasted effort down the chain. So, every batch in our facility is monitored for pH, temperature stability, and color clarity. Odd smells, slow-dissolving powders, or floaters can hint at process missteps. Customers have long memories, and so do we. Every detail matters because a mistake means trouble for sports nutrition firms, food processors, and pharma partners alike.

    What Sets Our L-Citrulline Apart

    Pure L-Citrulline should pump out as a free-flowing powder, bright white, with neutral taste and a quick dissolution profile. If the batch feels lumpy or tacky, that sends up warning flags for us. Moisture levels fall within steady, narrow bands by careful control of drying and final sieving. By keeping a tight rein on particle size and avoiding dustiness, we save our clients from trouble in automatic feeders or mix tanks. Each bag gets a tamper-proof liner and is sealed in-house to cut down on humidity pickup and accidental spills. We run GC, HPLC, and UV tests in-house well before the market calls for a specific assay, so quality meets the demand we expect from top supplement companies and pharmaceutical partners. We put batch numbers on every bag for full traceability. If a customer’s lab has questions, we can track ingredients and processing timestamps back to the source in under an hour.

    Specifications and Model Focus

    L-Citrulline usually comes in two main types: pure L-Citrulline and L-Citrulline Malate. Ours typically runs over 99% on L-Citrulline content and is D- and L- isomer tested for confidence in true chirality—these things matter in clinical formulas and regulatory audits. Moisture sits below 0.5% on our regular lots. Heavy metals and microbial counts meet or beat strict international standards. Besides the powder, granule options serve clients who want ultra-fast mix-in performance for instant supplements or high-speed industrial settings. Whether for a 25 kg drum or a smaller pharma-scale jar, the same care shapes the outcome. Flexibility in mesh size (generally 60-100 mesh) can be offered upon request to support various blending preferences without forcing anyone down a standard path.

    How L-Citrulline Is Used in the Real World

    There’s no shortcut to appreciating where L-Citrulline gets used most. Nutritional supplements lead the way, thanks to studies linking L-Citrulline to athletic performance, blood flow, and muscle recovery. Sports nutrition powders need a solubility profile that allows for quick mixing and minimal residue. Granular texture matters in these applications because clumped ingredients can throw off batching, leading to uneven scoop weights and wasted batches on high-throughput lines. Pharma partners, on the other hand, want the tightest purity specs and full documentation on every batch. Child nutrition and fortified food products require L-Citrulline to show no off-odors or color drift.

    L-Citrulline acts as a nitric oxide booster in sports drink powders, gel packs, and capsules. Its stability in solution and low moisture pickup ensure shelf life and consistent formulation across weather and shipping conditions. Sometimes clients approach us with custom particle requirements for effervescent tablets or want assurance that our L-Citrulline remains non-GMO and allergen-free. Long experience tells us that upfront conversations save headaches later—knowing who's using the product helps us shape every production run.

    Comparison to Other Amino Acids

    L-Citrulline stands apart from arginine and ornithine, common competitors in sports and pharmaceutical applications. Mammalian metabolism converts L-Citrulline to L-Arginine, but the two act differently once inside the body. L-Arginine supplements often show low absorption or quick breakdown in the gut, resulting in less effective increases in nitric oxide than the same dose of L-Citrulline. Over the years, customer case studies have confirmed that formula stability and yield get better with L-Citrulline, with less risk of odd flavors or spoilage. This isn’t just theory; it plays out in direct conversations with food engineers who want rapid dispersal and no residue in finished product bottling.

    In the context of L-Citrulline Malate, the addition of malic acid (usually in a 2:1 ratio by molar weight) can offer improved solubility and a sharper taste, which suits some sports drinks. Pure L-Citrulline, though, works best in clean-label or hypoallergenic applications where the lowest possible residuals are required. Each form requires different control levels in our factory, and the deviation between lots can spell the difference between a solid final beverage and a problematic one.

    Transparency, Testing, and Customer Trust

    Experience tells us that cutting corners with ingredient tracing or documentation comes back to haunt anyone in the manufacturing world. That’s why our QA/QC teams rigorously test each lot not only for purity but also for common allergens, residual solvents, and stability under stress conditions. Our equipment isn’t just top-line machinery; it’s tools we trust, calibrated weekly and overseen by technicians who understand the business consequences of mistakes. Trace metals, dioxin, and microbial screening ensure that what leaves our facility would meet not only local but also stringent international audit standards.

    Certificates of Analysis accompany every shipment with clear reference ranges, not just vague assurances. If a customer calls about odd performance, we pull up the original process log and check each step for deviations. Sometimes, a small shift in water content or particle size can alter mixing habits for downstream users. In those cases, we listen to the processor’s description, compare it to our controls, and advise on whether a solution needs to come from the product or the application method.

    Field Feedback and Lessons Learned

    Over twenty years of operations, certain patterns emerge in customer feedback. The most common problems for buyers revolve around clumping, delayed dissolution, or mild yellowing in older batches. We’ve traced clumping back to short drying cycles or slight humidity leaks into storage. These insights have driven us to upgrade packaging film, align on just-in-time production schedules, and keep direct oversight of our shipment partners. Yellowing tends to result from overexposure to light or ambient heat, so we now ship only in UV-proof, hermetically sealed drums—no plain cardboard.

    Some supplement blenders flagged initial bitterness in a few runs; this correlated to trace malic acid contamination when producing L-Citrulline Malate on shared lines. Now, dedicated lines handle malate-free and pure L-Citrulline, with swab tests run between each production switch. By keeping these lines separate, flavor and analysis come out as customers expect, and expensive product recalls fall away.

    Safety, Storage, and Handling Insights

    Keeping L-Citrulline stable takes more than paperwork or slogans. Floors, hoppers, and filter bags all receive routine checks for cross-contamination. During monsoon season or high humidity periods, extra sensors watch for moisture spikes, and additional dryers are kept ready. Finished batches never wait long in intermediate storage and move straight to final packaging. Staff on the line recognize off-notes or powder discoloration as early warning signs—no shift manager ignores those calls, since even a tiny contamination run can impact tons of product. In transport, cooled containers and pallet wrapping cut out sweating or product cake formation.

    Clients often ask for advice on warehouse shelf life. In our experience, L-Citrulline keeps well beyond two years under low-humidity, ambient conditions, but we stress the importance of keeping containers tightly sealed. Unopened, the powder usually stays bright and free-flowing, but exposure to air can bring clumpiness in rainy seasons or facilities with variable air conditioning. Simple checklists, handled by warehouse crew, outperform tech-based solutions in these cases; regular walk-throughs catch leaks or punctures far earlier than waiting on a monthly inventory review.

    Supporting Our Clients’ Success

    Our partners, from large sports nutrition brands to specialty food startups and generic drugmakers, each have their own priorities. Some want the highest possible nitrogen purity for use in injectable pharma preps. Others need bulk scale for food and beverage blending, where pricing and supply continuity rank highest. Open communication paves the way for smoother projects; it pays to share what’s possible and what isn’t at the outset. Overpromising, or hiding limitations, only leads to mistrust and frustration on both sides.

    Production windows line up with sales projections and early input from major clients. This lets us buy raw materials precisely, minimizing waste and keeping end prices stable throughout annual cycles. Lead times come down, unplanned outages drop lower each year, and our buyers benefit from the predictability. If a client signals a potential spike in demand, as happened during new product launches or recent upticks in the wellness market, our planning team ramps up scheduling right away. We put backup staff on key runs and add QA shifts during high volume periods, which sharpens consistency and gets product out the door faster.

    Addressing Regulatory and Market Shifts

    Every year brings new questions about ingredient sourcing, class labeling, or allowable claims for dietary supplements. We track food safety alerts globally—not because anyone forces us, but because tomorrow’s regulations could stop shipments at the dock unless documentation matches legal wording. Non-GMO, kosher, halal, and vegan status matter more today than they did a decade ago. Dedicated staff assemble and share clean, up-to-date certificates to help our clients pass their own audits and satisfy retail buyers.

    The supplement industry, especially in Europe, has watched for potential contaminants or residues that might slip into amino acid production. Years ago, a scare in the arginine market proved the value of strict batch testing and open reporting. L-Citrulline faces the same scrutiny. Our investment in in-house and third-party lab partnerships shortens response times, helping us address, not dodge, market realities as they evolve. We’re upfront about any minor variations in mesh, color, or solubility because even small changes in ingredient spec can break a finished formula’s quality.

    Looking Ahead: Sustainability and Innovation

    Manufacturing sustainability isn’t just a buzzword for us. Cutting energy costs and reducing waste pays back not only in lighter bills but also in cleaner, more consistent final product. Recovery and reuse of process water, careful sorting of byproducts, and minimizing batch runoff keep our plant lean and compliant with global environmental codes. Customers ask tougher questions about supply chain impacts these days, so we welcome visits and remote audits that check our claims. Openness helps everyone, ourselves included, raise standards year by year.

    We keep an ear to new research on L-Citrulline applications. Some of our clients test topical or functional beverage uses, looking for stability and taste masking solutions. Others want to know about encapsulation or granulation tricks to boost absorption or shelf life. Open dialogue with R&D labs and product development teams keeps innovation rolling. We don’t claim to have every answer, but hands-on experience lets us help partners work through technical challenges and steer clear of costly mistakes.

    Building Trust Through Reliability

    No product builds its own reputation; long relationships do. A reliable supply of L-Citrulline starts with a manufacturing floor that stands behind each run. Engineers, operators, and QA staff in our plant pay attention to changes in smell, color, and performance, not just because a spec sheet demands it, but because the next shipment’s reputation rides on every detail. By sharing real feedback, tracking performance tests, and adapting batch procedures for changing client needs, we earn trust through daily effort, not blanket claims.

    Looking at the past few years, challenges keep increasing. From raw material volatility during supply chain crises, to pressure for cleaner documentation and faster shipments, the manufacturing expectation bar only moves higher. Our answer comes down to communication, investment in skill, and always holding both the product and process to standards that go beyond industry minimums.

    Conclusion: The Manufacturer’s L-Citrulline Commitment

    We view every kilogram of L-Citrulline not just as a commodity, but a responsibility—one that starts in our raw material warehouse and follows the product through delivery, application, and beyond. Everything we've learned—from small failures that taught us to guard against cross-contamination, to major upgrades in packaging and analysis equipment—feeds back into our daily work. Our role as a manufacturer means standing up for transparency, supporting innovation, and quietly keeping the promises we've made to clients, no matter what shifts in the market or regulatory climate. L-Citrulline, done right, supports better products and builds real trust. We build that with every order, every batch, and every answer we give.