Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Kirenol

    • Product Name Kirenol
    • Alias ent-4,8,13-labdatrien-15,16-olide-6β-ol
    • Einecs 650-011-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    498470

    Name Kirenol
    Chemical Formula C20H28O4
    Molecular Weight 332.43 g/mol
    Cas Number 113027-06-6
    Source Siegesbeckia orientalis
    Appearance White to off-white powder
    Solubility Soluble in DMSO, methanol, and ethanol
    Storage Temperature 2-8°C (refrigerated)
    Purity ≥98% (HPLC)
    Iupac Name 12,16-Dihydroxy-pimara-7,15-dien-3-one

    As an accredited Kirenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Kirenol is packaged in a 100 mg amber glass vial with a tamper-evident cap, labeled with product purity and CAS number.
    Shipping Kirenol is shipped in secure, chemical-resistant packaging to ensure stability and safety during transit. The product is handled according to international regulations for laboratory chemicals, protected from moisture, heat, and light. Accompanied by a Material Safety Data Sheet (MSDS), shipments are tracked and may require a signature upon delivery for added security.
    Storage Kirenol should be stored in a cool, dry, and well-ventilated area away from direct sunlight and sources of ignition. Keep the container tightly sealed and store at room temperature, ideally between 2–8°C. Protect from moisture and incompatible substances. Ensure the storage area is equipped for handling hazardous chemicals, following appropriate safety and containment procedures as recommended by the material’s safety data sheet (MSDS).
    Application of Kirenol

    Purity 98%: Kirenol Purity 98% is used in pharmaceutical formulation, where it ensures consistent anti-inflammatory efficacy.

    Molecular Weight 346.39 g/mol: Kirenol Molecular Weight 346.39 g/mol is used in polymer synthesis, where it provides precise reaction control and product uniformity.

    Melting Point 210°C: Kirenol Melting Point 210°C is used in high-temperature extraction processes, where it facilitates effective thermal stability.

    Particle Size D90 < 10 µm: Kirenol Particle Size D90 < 10 µm is used in topical cream development, where it allows for enhanced skin penetration and bioavailability.

    Stability Temperature 60°C: Kirenol Stability Temperature 60°C is used in cosmetic preservative applications, where it maintains active integrity under storage conditions.

    Water Solubility 5 mg/mL: Kirenol Water Solubility 5 mg/mL is used in injectable solution preparation, where it promotes rapid dissolution and homogeneous formulation.

    Viscosity Grade 200 cP: Kirenol Viscosity Grade 200 cP is used in gel manufacturing, where it delivers optimal spreadability and application consistency.

    Assay 99% HPLC: Kirenol Assay 99% HPLC is used in reference standard calibration, where it guarantees analytical accuracy and reproducibility.

    Residual Solvent < 0.5%: Kirenol Residual Solvent < 0.5% is used in dietary supplement production, where it ensures product safety and compliance.

    Optical Purity > 98% ee: Kirenol Optical Purity > 98% ee is used in enantioselective synthesis, where it enhances biological target specificity.

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    Certification & Compliance
    More Introduction

    Introducing Kirenol – Perspective from the Manufacturer

    Bringing Kirenol from Lab Bench to Reliable Supply

    As a company focused on precision extraction and synthesis, we have worked with a wide range of natural and engineered products. Among the most technically challenging ingredients we’ve scaled is Kirenol, a labdane-type diterpenoid known to those working in pharmacological research and advanced formulation work. Early on, our chemists encountered Kirenol in the course of research on natural anti-inflammatory agents derived from Siegesbeckia herbs. In the beginning, only small yields trickled out of the lab glassware, but interest from pharmaceutical, cosmeceutical, and veterinary industries drove us to refine and debug all aspects of the process—extraction, purification, crystallization, and long-term stabilization.

    Kirenol comes with a concentrated history both in traditional medicinal systems and in high-value research. Academic teams reported its robust anti-inflammatory, anti-arthritic, and antioxidant profiles. Still, few suppliers consistently delivered a reliable, high-purity concentrate without solvent or raw material inconsistencies muddying up the chromatographic signature. Our process chains root out batch-to-batch variation. We developed dedicated lines using both solvent extraction and controlled semi-synthetic methods, verified by extensive HPLC, MS, and NMR data, so researchers and formulation specialists could work with the pure molecule—confident each shipment met the documented spec.

    What Makes Kirenol Distinct in Advanced Research and Production

    Kirenol differs from many routine compound supplies. Just isolating the molecule calls for expertise with both plant extraction and modern organic purification. The molecule itself features a structure that can interact on multiple biological pathways, which makes it more than a one-trick ingredient. In our facility, we prepare Kirenol in concentrations up to 98% purity for direct analytical and research use. The bulk of requests come from teams looking to support ongoing inflammation studies or to create next-generation topical and oral formulations.

    Compared to other diterpenoids in circulation, Kirenol stands out for its stability profile and relative safety in both cell cultures and small-animal tests, as reported by independent labs. The compound survives most solvent handling routines without rapid decomposition or loss of function. That kind of resilience matters for customers designing multi-step synthesis or extraction protocols downstream. Our technical team learned this through years of hands-on troubleshooting, as clients found inferior grades from resellers prone to degradation or contamination that ruined repeatability.

    From our vantage point, Kirenol’s sourcing journey makes the biggest difference. Field collection of Siegesbeckia material, especially the aboveground sections wherein Kirenol concentrates, determines raw input quality. Our procurement division works directly with growers practicing standardized, pesticide-free cultivation methods, as these agricultural subtleties make all the difference in avoiding batch failures. We process every input lot with full trace documentation—no combined lots, no untracked wild sources. Customers sometimes assume plant extracts are interchangeable, but every Kirenol batch tells a story through HPLC traces and purity analysis.

    Reliability in Laboratory Settings—Key Considerations with Kirenol

    From the outset, researchers want to trust that Kirenol will yield reproducible results. Purity is not just a number—it’s a measure of what isn't present in the vial. Trace plant waxes, affected by the extraction phase, can create false positives in enzyme or cell-based screens. Careless handling or storage cuts shelf life dramatically. That’s why our technical staff built systems not just for one-time batch purity, but for consistent handling, packaging, and temperature control that span the entire logistics chain.

    In-house, we perform parallel tests with every production run. Beyond certifying basic purity, our team runs stability trials under accelerated and room temperature conditions, checking for any signs of decomposition such as color shift, precipitate formation, or TLC anomalies after exposure to moisture or light. Over several years of maintaining continuous logs, our packaging strategy changed. We shifted from standard glassware to amber borosilicate vials with induction-sealed caps and nitrogen-flush protocols.

    Technical clients sometimes ask why Kirenol prices fluctuate or why lead times can spike in certain seasons. The reality is twofold: raw herb harvests depend on climate, and Kirenol’s natural content can fluctuate even between adjacent plots. Scaling up to larger volumes remains a challenge because process adjustments, even something as simple as switching a peristaltic pump, change isolation yields. Our senior chemist logs every modification, and retrospective analysis guides each production step, so surprises are caught early and standards stay high.

    Core Usage Scenarios and Application Advice

    Based on years collaborating with R&D clients, the primary applications of our Kirenol batches revolve around three pillars: pharmaceutical research, formulation development, and advanced analytical work. In inflammation research, many groups use Kirenol as a comparator or control alongside corticosteroid benchmarks. They report that its reproducible IC50 range against TNF-α and IL-6 targets makes it valuable for both in vitro and in vivo protocols. From feedback, Kirenol’s performance as an adjunct in arthritis models and post-injury inflammation suggests potential routes for new drug discovery.

    Formulation specialists have experimented with Kirenol both as a primary ingredient in topicals for joint care and as a quality marker in broader anti-inflammatory blends. In crowded herbal formulation industries, clear dose control and lab grade markers establish credibility. In our own QA trials, Kirenol maintains compatibility with standard emollients, oils, and controlled-release carriers. Purity above 98% proves crucial, as trace impurities can affect color, stability, and bioavailability in finished goods.

    Analytical chemists rely on accurate standards for method validation. Our Kirenol has functioned as a reference in HPLC and LC-MS protocols for quality control both within our lines and in independent contract labs. Because of our in-house analytics, our staff can provide detailed batch certificates with every shipment—no hidden variables or generic documentation.

    Practical Differences in Manufacturing Compared to Other Diterpenoids and Plant Extracts

    Pulling Kirenol out of raw Siegesbeckia material shows stark contrasts to standard extraction of simpler plant molecules. Many suppliers of plant extracts combine raw bulk with varying moisture or pesticide profiles, taking shortcuts in extraction or dewaxing routines. Our plant scientists and extraction engineers take a slow and measured approach, keen to document every deviation and its impact on the final molecule’s structure. We test every phase for unwanted metallic traces, pesticide residues, or breakdown products before committing to downstream purification.

    Kirenol’s molecular profile adds another layer of complexity—unlike flavonoids or basic monoterpenes, Kirenol resists standard hydrolytic breakdown. We deploy tailored resin and solvent extraction, followed by flash chromatography under controlled vacuum and temperature cycles. This approach requires more labor and technical experience. We maintain a policy of open process improvement logs so we can adapt as new research or customer requirements emerge.

    Other diterpenoids often originate from more widely cultivated species, sometimes bulk processed in centralized facilities with little direct source control. Our Kirenol retains its provenance; each gram links back to a defined lot, with complete analytical fingerprints stored in our secure databases and cross-referenced with supplier identity confirmation. Quality isn’t just tested at the end—it is monitored at every junction, from collection to the final sealed bottle.

    What High-Quality Kirenol Really Means for Customers

    Clients come with high technical expectations. For those running toxicity, anti-inflammation, or metabolic pathway investigations, even trace variations in purity yield different experimental outcomes. We receive feedback directly from field researchers—one batch that does not align with their prior experience prompts lengthy troubleshooting and lost project time. Our role is to reduce that uncertainty; we treat every Kirenol lot like a clinical sample, ensuring reproducibility.

    In sectors exploring new drug candidates or developing OTC topicals, clear traceability ensures safety and regulatory compliance. In our own internal trials, we mimic customer storage routines, checking how each batch holds up to repeated freeze-thaw cycles, room temperature exposure, or even accidental light leaks. Any food-grade product entering clinical or commercial supply chains gets this degree of scrutiny from our side, but natural products raise additional hurdles—microbiological stability and solvent residue clearance get special focus with Kirenol.

    Working closely with our analytical department, we document every deviation, no matter how small. This transparency lets our clients make informed decisions. It also lets us catch and remedy problems well in advance of a customer ever seeing them. Listening to customer lab stories often exposes pain points others overlook—routine shipment delays, unexpected solvent odors, unexplained color changes, or “document gaps” that cost downstream time and trust.

    How Practical Solutions Address Industry Concerns

    Building a long-term track record with Kirenol depends on more than just chemistry know-how. Transportation, especially across seasonal climate variations, affects stability. We upgraded to custom-cushioned, temperature-moderated containers and plan expedited routes for longer-haul destinations. Every year, we reassess packaging to handle changing compliance or customer storage requirements, keeping a close eye on any new transport restrictions flagged by international regulations.

    On the digital side, our staff built a secure portal offering batch-by-batch download of COAs, origin statements, and analytical fingerprints. Customers know what to expect with every shipment, which improves confidence and streamlines their own documentation process. Our team advises purchasing managers and lab techs alike on best storage practices—short and mid-term storage at controlled conditions, sealed packaging in low-humidity environments, with desiccant use for longer periods.

    To further improve reliability, we launched a proactive feedback system, sending out routine follow-up surveys to all Kirenol recipients. If trends emerge—such as a spike in queries about minor solvent residue or late carrier delivery—we get early warning signals. As a result, we adapt in real time, fixing processes before they snowball into systematic issues.

    Comparison with Broader Market Offerings

    Customers often ask us how our Kirenol compares with what else appears in the global marketplace. We have analyzed dozens of competitive samples: many show non-specific labeling, variable purity (much lower than stated on their certificates), off-odors, or coloration suggesting oxidation. Some of these materials look passable on a quick scan, but barely survive rigorous lab screening.

    The most acute problems with lower-tier supplies tie to inconsistent extraction methods and poor post-processing discipline. Solvent residues (especially aggressive chlorinated solvents) or leftover pesticides from the source plant compromise both safety and efficacy. Researchers not only face failed experiments—they risk cross-contaminating sensitive equipment or invalidating years of published data.

    By maintaining near 100% control of the entire processing chain, from field to finished form, we eliminate chances for dilution, substitution, or contamination. Every Kirenol shipment leaves our facility with clear spectral data and, crucially, open production logs so customers can audit our process. We view this not as an add-on, but as the minimum required to serve technical end-users.

    Our team stands behind every Kirenol order. If a customer ever encounters an unexpected analytical anomaly, we offer both immediate batch investigation and technical dialogue, sharing raw data and insight drawn from hundreds of trial and batch records accumulated over the years. As research and development in inflammation and related pathways continues to grow, our investment in Kirenol’s reliability and precision supply has only deepened—each year brings new learning, new adjustments, new partnerships.

    Looking Forward—Continual Improvement in Kirenol Manufacturing

    We constantly review both the science and the customer experience surrounding Kirenol. Our chemists stay in tune with academic and clinical literature, watching for new applications, mechanisms, and regulatory shifts. Each piece of customer feedback cycles directly into our system, generating practical changes in extraction tuning, QC protocol, or customer support routines.

    With ongoing research broadening the understanding of Kirenol’s pharmacodynamics and potential applications, the standards for purity, traceability, and regulatory compliance continue to rise. We meet these expectations through investment in analytical instrumentation, staff education, and a process culture that values transparency over expedience.

    Since the beginning, we saw Kirenol not as a standard extract, but as a benchmark for how natural products can serve scientific progress, provided they are made with the same care as any pharma-grade raw material. From raw plant field to HPLC-verified shipment, every decision focuses on reproducibility and clear, direct communication with the technical communities we support.