Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Hydroxypropyl Cellulose

    • Product Name Hydroxypropyl Cellulose
    • Alias HPC
    • Einecs 248-384-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    221498

    Cas Number 9004-64-2
    Molecular Formula (C6H7O2(OH)x(OC3H6O)y)n
    Appearance White to yellowish powder
    Solubility In Water Soluble
    Ph Value 5.0–8.5 (1% aqueous solution)
    Viscosity Varies (dependent on grade and concentration)
    Melting Point N/A (decomposes before melting)
    Moisture Content <5%
    Degree Of Substitution 0.35–1.4 (hydroxypropyl substitution per anhydroglucose unit)
    Particle Size Typically 80–150 mesh
    Odor Odorless
    Stability Stable under recommended storage conditions

    As an accredited Hydroxypropyl Cellulose factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Hydroxypropyl Cellulose is packaged in a sealed, moisture-resistant 500g plastic container, labeled with product details, safety, and handling instructions.
    Shipping Hydroxypropyl Cellulose is shipped in tightly sealed, moisture-resistant containers, typically fiber drums or polyethylene-lined bags, to prevent contamination and moisture absorption. It should be stored and transported in a cool, dry place away from direct sunlight and incompatible substances. Proper labeling and documentation according to regulatory requirements ensure safe handling and delivery.
    Storage Hydroxypropyl Cellulose should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of heat or ignition. It must be protected from moisture and incompatible substances. Avoid exposure to direct sunlight. Proper storage helps maintain stability and quality, preventing clumping or degradation. Follow all relevant safety and handling guidelines when storing this chemical.
    Application of Hydroxypropyl Cellulose

    Viscosity Grade: Hydroxypropyl Cellulose with high viscosity grade is used in ophthalmic solutions, where it enhances tear film stability and prolongs ocular hydration.

    Purity %: Hydroxypropyl Cellulose of 99% purity is used in pharmaceutical tablet coatings, where it ensures consistent film formation and minimizes impurity-induced defects.

    Particle Size: Hydroxypropyl Cellulose with fine particle size is used in topical gels, where it provides uniform texture and rapid dissolution.

    Molecular Weight: Hydroxypropyl Cellulose with low molecular weight is used in oral suspensions, where it improves solubility and reduces sedimentation.

    Melting Point: Hydroxypropyl Cellulose with a melting point above 200°C is used in heat-processed food formulations, where it maintains product stability during processing.

    Stability Temperature: Hydroxypropyl Cellulose stable at up to 120°C is used in cosmetics emulsions, where it preserves viscosity under elevated storage conditions.

    pH Range: Hydroxypropyl Cellulose stable between pH 3 to 10 is used in dermatological creams, where it ensures consistent rheology across diverse formulations.

    Water Solubility: Hydroxypropyl Cellulose with high water solubility is used in water-based adhesives, where it enables rapid dispersion and strong bonding.

    Substitution Degree: Hydroxypropyl Cellulose with high hydroxypropyl substitution degree is used in controlled-release drug delivery, where it modulates active ingredient release profiles.

    Bulk Density: Hydroxypropyl Cellulose with low bulk density is used in aerosol formulations, where it facilitates even suspension and optimal spray performance.

    Free Quote

    Competitive Hydroxypropyl Cellulose prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

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    Certification & Compliance
    More Introduction

    Hydroxypropyl Cellulose – Blending Expertise With Proven Results

    Standing Behind Hydroxypropyl Cellulose From Experience

    Every batch of hydroxypropyl cellulose that leaves our plant reflects decades in polymer engineering and close contact with real customers. We’ve put in the time developing hydroxypropyl cellulose (HPC) grades that mix ease of use, reliable quality, and real process flexibility. Over the years, this water-soluble cellulose ether has become a backbone in both industrial and pharmaceutical lines of work.

    We work daily with national and global formulators who know that the details behind each grade matter. Through long production runs and lab-scale trials, our team has had a close look at what makes a hydroxypropyl cellulose grade productive, and what gives customers trouble. That’s why we’re always factoring in batch viscosity, particle size, true hydroxypropoxyl content, moisture levels, and handling safety—not just ticking the “cellulose ether” box.

    Hydroxypropyl Cellulose Models and Key Specs

    What comes off our reactors is more than a generic additive. We keep a clear grade separation based on different needs: low, medium, and high viscosity models fit applications that range from tablet binding to coatings and thickening. Our typical products such as HPC-L (low viscosity; about 45-90 cps in 2% solution, Brookfield), HPC-M (medium viscosity; about 400-2,000 cps), and HPC-H (high viscosity; above 3,500 cps) each address unique technical demands. We keep final moisture content low and aim for standardized substitution patterns, so customers can count on consistent solubility—from batch one to batch one hundred.

    Customers in tablet production look for precise powder flow and reproducible disintegration profiles. Building material formulators want easy dispersibility, predictable set times, and robust film formation. In food and cosmetic plants, we keep color and taste contaminants in check, while making sure the polymer disperses without unwanted clumping. Every technical team watching the bottom line relies on this practical, batch-to-batch reliability.

    Real Use Cases: What Hydroxypropyl Cellulose Delivers

    Our focus stays on what actually works in process. Pharmaceutical manufacturers look to hydroxypropyl cellulose for strong tablet binding, stable disintegration, and clean dissolution. Because our products dissolve in both water and organic solvents, formulators get control—they don’t sacrifice mechanical strength when optimizing release rates.

    HPC improves solubility in challenging active pharmaceutical ingredient (API) matrices. Our experience developing direct compression blends has shown that choosing the right HPC viscosity controls tablet compressibility, friability, and handling loss. Wet granulation batches become more robust and less sensitive to process swings—customers report fewer rejected lots and time saved in set-up.

    Film coating specialists rely on our HPC grades to deliver uniform, defect-free films. These coatings enhance appearance, mask taste, and provide critical moisture barriers. We have seen more consistent spraying and lower dusting when film formulation aligns with viscosity and particle size distributions that we manufacture. This lowers the risk of process shutdowns and improves batch yields.

    Dietary supplement makers and food processors want HPC for its low-calorie, non-tacky thickening. In some bakery and beverage applications, hydroxypropyl cellulose offers clean-label texture modification with no off-flavor. Our plant’s experience with food-grade lines pivots on keeping the polymer colorless, odorless, and free of aggressive solvents.

    Cosmetic chemists and personal care brands ask for HPC in skin creams, gels, and lotions. Their focus is smooth spreadability, suspension of fragrance or actives, and a stable viscosity profile over wide temperature swings. We manage cross-contamination risks, clean our lines intensively, and offer real traceability—especially for high sensitivity products.

    Beyond these large-volume uses, there’s demand in adhesives, inks, and foundry coatings. In our experience, technical service teams always stress the need for tailored particle sizes for thickener blends, emulsions, or spray applications. We take product consistency seriously—a lot of subsequent quality headaches start with inconsistent polymer powders.

    How We Keep Our Hydroxypropyl Cellulose Consistent

    Earning trust in this market depends on repeatability. Every shift, our operators follow strict raw material checks, and process control steps are automated to cut out variation. We batch test for viscosity in controlled humidity rooms, measure MW distributions, and regularly send samples for third-party regulatory review. Our on-site technical team regularly audits procedure and works directly with customer feedback—learned lessons create tomorrow’s control improvements.

    Packaging matters too. We commit to lining drums and bags, sealing against moisture ingress, and date-stamping lots for traceability. Customers have flagged minor moisture changes within bags as the cause of film defects or uneven flow—over the years, even these small details make the difference between a smooth operation and a week wasted troubleshooting at the customer’s plant.

    True performance goes beyond technical sheets. We know many manufacturers have been burned by hydroxypropyl cellulose with surprise fiber contaminants, dust, or variable particle size. We grind, sieve, and blend under conditions that actively minimize cross-contamination and track every batch. It’s not about ticking off compliance paperwork; it’s about protecting downstream value for customers who run 24/7 operations and can’t afford production delays.

    Comparing Hydroxypropyl Cellulose to Other Cellulose Ethers

    Years of customer troubleshooting compare hydroxypropyl cellulose directly to hydroxypropyl methylcellulose (HPMC), methylcellulose (MC), and sodium carboxymethylcellulose (NaCMC). Each one brings different viscosity levels, solubility, and thermal gelation features.

    Our hydroxypropyl cellulose stands out for cold-water and some organic solvent solubility. Unlike HPMC and MC, which gel on heating, hydroxypropyl cellulose maintains stability across reasonable temperature swings. In process, this means shorter hydration times, no clumping under standard mixing, and reliable performance even if batch temperatures swing. Customers using high-speed blending systems choose our HPC to shorten mixing cycles for both liquids and powders.

    In tablet production, hydroxypropyl cellulose’s non-ionic character resists ionic interactions with actives or excipients—this can make the difference between clean dissolution and unpredictable release rates. Compared to carboxymethylcellulose, which brings an anionic charge and different solubility behavior, hydroxypropyl cellulose works in a wider range of conditions—especially heavy salt or electrolyte concentrations. We get direct calls from compounding pharmacists who switched to our HPC to avoid gelling or precipitation at higher saline levels.

    In coatings, hydroxypropyl cellulose outperforms HPMC in adhesion to hydrophobic surfaces and gives clearer, more transparent films. Some formulators still opt for HPMC for cost savings, but many switch back to HPC when haze or shell formation creates performance problems. Over many seasons, we’ve helped corrugated packaging and specialty coating teams balance clarity and barrier functionality by suggesting specific HPC grades.

    For food and personal care, taste and odor matter. Our HPC grades keep low flavor pickup compared to some MC products, and being non-ionic, do not affect flavor stability in delicate food matrices.

    Regulatory and Supply Chain Confidence

    Regulatory expectations keep moving, especially in pharma and food. We maintain GMP production on critical lines, with full traceability and documentation. We build our lines to keep cross-contamination out, controlling for potential allergens and regularly breaking down lines for deep cleaning. Every batch leaves our plant marked by both date and grade, certified with a certificate of analysis tied to both our in-house tests and any specified pharmacopoeia.

    We believe traceability shouldn’t be an afterthought—it’s part of our daily operation. We’ve participated in customer audits and regulatory reviews across multiple continents. Customers can review our records without hassle, and we provide original data for any root-cause investigations. During spikes in demand—especially pandemic years—our inventory controls helped insulate partner customers from raw material shocks. We plan long-term on supply, committing regular forward ordering to raw material sources, and auditing our own supply chain for consistency.

    Troubleshooting in Real World Production

    No production plant runs perfectly every day. Over many years, we’ve supported customers coping with calendaring blockages, inconsistent dispersions, and tablet sticking. Whether in a pharma compression line or an industrial blending tower, the first variable we check is polymer batch quality and handling conditions.

    Some customers running open-bag processes see minor moisture absorption impact powder flow—so we recommend sealed transfer and minimal storage time before use. Others who rely on very fine powders for ultrathin coatings report dusting; using slightly coarser grades or pre-blending before full hydration often clears up the problem. If viscosity shifts crop up, we’re able to trace these back to raw material fluctuations or handling temperature, not just “out of spec” polymer.

    The difference with our company is the technical accessibility. Our support teams have worked the same lines our customers use, so they recognize problems fast. We’ve helped optimize hydration processes, recommended batch-mixing parameters, and fine-tuned blends on-site with partners. No cookbook advice, just tested process fixes.

    Environment, Safety, And Improvement

    Industrial chemical plants run only as well as their process control and safety. We minimize solvent usage at every stage, favoring water-based processing where possible, and carry out emissions control and waste minimization projects. Side streams go through proper treatment before leaving the plant. We keep up with global and national requirements, regularly updating our process and formulation records to match changing rules.

    Worker health and safety affect polymer quality too. We keep all bulk powders in closed handling systems, manage dust filtration, and train operators to spot anomalies in real time. Our plant has an open-door incident reporting culture. Any near-miss gets logged and followed through—whether it’s a faulty valve or material spill. We have found over the years that a well-trained line worker spots contamination or moisture uptake before it infects a bulk lot. Everyone on the team knows they make a difference to that final bag of hydroxypropyl cellulose, and, just as important, to the downstream plant yards and end product safety.

    We keep improving our formulas, equipment, and product grades based on feedback and changing requirements. Whether a new pharma guideline appears, or a coating application finds stricter VOC enforcement, we shift our own standards up in response. There’s no room for “close enough” in batch-controlled industries.

    The Value We See In Working Long-Term With Hydroxypropyl Cellulose

    For us, hydroxypropyl cellulose isn’t just a chemical listing—it’s the focus of long-term investment. We’ve seen early challenges in the field, failed new product launches, successful process improvements, and steady evolution in markets around the world. Customers trust that every drum ships out clean, pure, and on spec because of the work and detail we put into each production cycle. We recognize that credibility lasts only as long as the product performs.

    Hydroxypropyl cellulose stands at an intersection of reliability, versatility, and safety. It bridges process needs in pharmaceuticals, food, personal care, industrial coatings, adhesives, ceramics, and more. Our day-to-day work in plant control, customer dialogue, technical audits, and product development means that every grade has a backstory—and a set of real-world applications proven in action. Whether your operation needs a high-viscosity binding agent or a food-grade thickener, it’s the expertise behind the product that makes the difference.