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Hydrocholine Tartrate

    • Product Name Hydrocholine Tartrate
    • Alias Choline Alfoscerate
    • Einecs 200-713-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    789575

    Chemical Name Hydrocholine Tartrate
    Synonyms Choline bitartrate
    Molecular Formula C9H19NO7
    Molecular Weight 253.25 g/mol
    Appearance White crystalline powder
    Solubility In Water Highly soluble
    Odor Odorless
    Taste Slightly bitter
    Storage Conditions Store in a cool, dry place
    Melting Point 151-155°C
    Cas Number 87-67-2
    Ph Value 5.5-7.0 (1% solution)
    Stability Stable under recommended conditions
    Usage Nutritional supplement
    Route Of Administration Oral

    As an accredited Hydrocholine Tartrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Hydrocholine Tartrate is packaged in a sealed, amber glass bottle containing 100 grams, clearly labeled with safety and handling instructions.
    Shipping Hydrocholine Tartrate should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled per regulatory guidelines. Store and transport in cool, dry conditions. Handle with care to prevent spills or leaks, and comply with all relevant hazardous material shipping regulations. Ensure proper documentation accompanies the shipment for safety and compliance.
    Storage Hydrocholine tartrate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Protect it from moisture and direct sunlight. Store at room temperature, ideally between 15–25°C (59–77°F). Ensure the storage area is clearly labeled and access is restricted to authorized personnel.
    Application of Hydrocholine Tartrate

    Purity 98%: Hydrocholine Tartrate purity 98% is used in pharmaceutical formulations, where it ensures high bioavailability and consistent therapeutic efficacy.

    Melting Point 290°C: Hydrocholine Tartrate melting point 290°C is used in the synthesis of active pharmaceutical ingredients, where thermal stability allows robust processing at elevated temperatures.

    Particle Size <50 µm: Hydrocholine Tartrate particle size <50 µm is used in veterinary feed supplements, where fine dispersion increases absorption rates and uniform nutrient delivery.

    Moisture Content <0.5%: Hydrocholine Tartrate moisture content <0.5% is used in dry-blend nutraceutical powders, where low moisture minimizes degradation and extends product shelf life.

    Solubility >50 g/L (water): Hydrocholine Tartrate solubility >50 g/L (water) is used in injectable drug preparations, where high solubility promotes rapid formulation and patient compliance.

    Stability Temperature up to 80°C: Hydrocholine Tartrate stability temperature up to 80°C is used in thermo-processed dietary supplements, where sustained structural integrity under heat preserves functional activity.

    Assay 99% (Titration): Hydrocholine Tartrate assay 99% (titration) is used in clinical research compounds, where precise assay control delivers reproducible experimental results.

    Bulk Density 0.45 g/cm³: Hydrocholine Tartrate bulk density 0.45 g/cm³ is used in tablet manufacturing, where optimal flow properties improve compression efficiency and tablet uniformity.

    Optical Rotation +17° (in water): Hydrocholine Tartrate optical rotation +17° (in water) is used in chiral intermediate synthesis, where defined chirality ensures enantiopure product outcome.

    Heavy Metals <10 ppm: Hydrocholine Tartrate heavy metals <10 ppm is used in pediatric nutraceuticals, where minimized toxic impurities meet safety and regulatory standards.

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    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Introducing Hydrocholine Tartrate: Manufacturer’s Ground-Level Perspective

    A Closer Look at Hydrocholine Tartrate Production

    Producing Hydrocholine Tartrate isn’t just about mixing two chemicals and calling it a day. It’s shaped by years of adjustments—not only to process tweaks and raw material selection, but also to what we’ve learned by running batch after batch. Our team checks in at every step. From the very beginning, the base choline source comes in with a certain moisture level and on the wrong day, a temperature swing in the warehouse can change how that reacts with tartaric acid in the reactor. Our model, HTT-99, comes out at not less than 99% purity on dry basis. Getting there takes careful timing, controlled reaction environments, and repeated filtration—not shortcuts.

    Out on the shop floor, we’ve found that even the seemingly small details make a difference. The reaction gives off a fair bit of heat, so temperature control isn’t optional. Overlook it, and yield drops or the crystal habit shifts. The wrong crystalline structure might mean caking later, slower dissolving, or batch-to-batch inconsistency—something our buyers in feeds, pharma, and nutraceuticals all notice. Consistent crystal size makes downstream application easier, whether the end user blends the powder into a tablet matrix or needs it to dissolve smoothly into solution.

    What Sets Hydrocholine Tartrate Apart

    Our team talks a lot about what sets hydrocholine tartrate apart from other choline salts, such as choline chloride or choline bitartrate. Hydrocholine tartrate’s combination of choline with tartaric acid brings a noticeably milder taste profile. This matters—not for us as producers, but for those formulating beverages, animal feeds, or chewable tablets, where consumer acceptance affects product adoption.

    Compared to choline chloride, hydrocholine tartrate remains stable over a wider range of temperatures and doesn’t pick up moisture as readily, so storage and handling cause fewer headaches. Choline bitartrate, while similar, has shown us to be slightly more hygroscopic, making it harder to maintain a free-flowing product, especially in humid regions. With the tartaric acid element, we see minimal pH impact on finished blends, lowering the likelihood of formulation drift over shelf life.

    In terms of chemical specifications, our quality assurance team relies on validated high-performance liquid chromatography (HPLC) methods to verify active choline content. Impurity profiles go through regular scrutiny, with particular attention paid to tertiary amine byproducts that can crop up if reaction temperatures spike or raw materials deviate from spec. We never take “good enough” as the cutoff—internal batch records and annual stability studies ensure every drum matches our own history.

    Applications Rooted in Practical Experience

    It’s always been interesting to watch how hydrocholine tartrate ends up in so many different industries. Feed manufacturers reach out, looking for a source of choline that survives pelleting and extrusion. They report better nutrient retention with our product, compared to choline chloride, which can degrade under high heat. Over in nutraceuticals, we hear about faster disintegration rates with our batch, owing to the fine particle profile we’ve refined. Human health supplements call for strict control, especially on non-volatile impurities. To address this, our final drying step removes volatiles, monitored by loss-on-drying tests specific to tartrate blends.

    We’ve worked alongside beverage developers trying to mask the aftertaste of functional ingredients. They found that hydrocholine tartrate left a much cleaner flavor in prototypes compared to other choline sources. This feedback pushed us to refine our process further—focusing on odor and color before the API ever leaves our door. Each stage, from reaction to finished powder, gets a full sensory review. If something is off—be it a faint amine-like odor or a yellowish hue—our crew halts production to backtrack and pinpoint the deviation. Especially for pharma customers, who demand the tightest tolerances, following this process control is non-negotiable.

    Why Purity and Consistency Drive Everything

    No matter the industry, users echo one recurring frustration: batch-to-batch variation. Hydrocholine tartrate isn’t forgiving in this regard. Too much residual solvent, and downstream complaints follow—off-odors in final blends, or moisture migration that can ruin an entire run. We invested in additional oven-drying and a second crystallization step. Here, physical labor and experience still rule; operators can spot defects even before the results come back from QC.

    Some might think the difference between 98% and 99% purity seems trivial. In our experience, that 1% can make the difference between a tablet that passes dissolution and one that doesn’t—between a feed batch that delivers intended benefits and one the customer rejects. Purity isn’t just a number, but a reflection of everything that’s happened along the manufacturing chain. By keeping full in-house control from incoming raw materials through finished goods, we’ve avoided the headaches some market players face when buying intermediary blends or outsourcing core steps.

    Environmental Factors and Process Choices

    Our customers have a growing interest in sustainable manufacturing, and we see it firsthand in contract terms and audit standards. Our production line recovers solvents, minimizes wash-water, and emphasizes closed-loop filtration. We’ve had to adapt these practices over the years. At first, water usage ran high, with cleaning procedures after every shift. By overhauling CIP (clean-in-place) systems, cutting rinse steps, and moving to semi-automated drum handling, we’ve dropped water use by about 30%. Efforts to reduce solvent emissions led us to install extra reflux condensers, further lowering our impact.

    Packaging gets the same attention. Double-layer PE bags protect hydrocholine tartrate powder in drums, reducing the chance of moisture pickup during cross-country and sea transport. We trialed different bagging setups and found that heat-sealed liners delivered the best moisture barrier over long hauls, especially when containers hit tropical climates. Inconsistent sealing once led to customer complaints about clumping, but after investment into automated bagging lines, incidents have dropped toward zero.

    Real-World Challenges and Adaptations

    Manufacturing isn’t immune to setbacks, as anyone who’s spent time around batch reactors learns quickly. A few years back, a global tartaric acid shortage tested our flexibility. We ended up qualifying backup suppliers, some from half a world away. Rather than risk variability, we doubled up on incoming raw material testing, using titration and melting point checks to weed out off-grade stock. We also learned the hard way about cross-contamination risks when switching between similar products, dedicating equipment and cleaning validation protocols to guarantee product integrity.

    Raw material shifts affect outcomes, not just by changing specs on paper but by impacting handling, storage conditions, and resulting product behavior. For instance, a recent lot of choline base came fine but hygroscopic, soaking up moisture on humid days before hitting the reactor. After adjusting storage humidification and operator training, yields steadied again, and powder flow improved. The right process controls and hands-on experience often matter more than any technical manual.

    Supporting Facts and Continuous Improvement

    The backbone of our process lies in repeatable, validated results. Certificates of Analysis (CoA) back every lot shipped, with choline content measured by reliable analytic standards. We maintain a log of customer feedback—which, at times, shines a light on issues more telling than lab results. Two years ago, a distributor reported powder clumping in a new region. Our investigation traced it to fluctuations in ambient humidity during packaging, not an underlying product flaw. By updating packing room specs and training on environmental monitoring, we saw those complaints fade.

    Our production team meets regularly to review deviations, customer notes, and audit findings. Changes don’t happen by fiat; they’re rolled out with retraining and follow-up. This has fostered a culture where line operators flag concerns early—something quality control teams appreciate. We encourage transparency because the stakes are high: a single bad batch can undermine trust built over years. Catching problems on the line saves everyone further downstream, from distributors to end users.

    User-Focused Approach: Listening and Responding

    It’s not lost on us that most people don’t spend their days thinking about hydrocholine tartrate, so our conversations with users tend to focus on what matters to them. Customers in animal nutrition expect a resilient choline source, one that handles pelleting temperatures without breaking down. Feedback from the field tells us when heat stability or dustiness needs improvement. We’ve tweaked our crystal habit and drying cycles to reduce product loss and increase shelf life, cutting caking and enhancing flow—a small change with a big impact for mill operators.

    Discussion with supplement formulators centers on taste and dispersibility. Sometimes, a minor adjustment in particle size distribution or drying profile makes a chewable tablet more palatable or a powder easy to mix. We remain responsive, not only to large orders but also to startups and researchers piloting new products. These dialogues help shape our manufacturing priorities. Being directly involved lets us act quickly on requests, such as developing a batch with tighter microbial counts for immune-compromised populations or customizing the blend method to reduce dust in confined production space.

    Working With Hydrocholine Tartrate: Practical Knowledge

    After years in production, we know handling matters as much as the chemistry. Warehouse operators keep hydrocholine tartrate under cool, dry conditions, far from oxidizing agents and moisture sources. It packs tightly in fiber drums lined with PE—both to minimize static and to shield from occasional climate swings. During shipping season, we load based on temperature forecasts, rerouting goods as needed to avoid extreme exposures. Our team updates records daily during rainy spells, and after a steep learning curve some time ago, each operator now checks every drum for moisture before release.

    Downstream users have told us about mixing challenges in automated lines. To address this, we aligned our milling particle size with requirements of high-speed blenders. Over time, we refined our process to maintain a fine, free-flowing powder. This didn’t happen by chance, but by regular audits of in-line sieving equipment, periodic blade inspections, and staff retraining. Small investments—like a sieve calibration schedule and humidity alerts in storage—led to marked improvements in product performance and customer satisfaction.

    Regulatory Perspective and Accountability

    We keep a close eye on the evolving regulatory scene. Hydrocholine tartrate for feed market use differs in requirements from its counterpart heading to nutraceutical or pharma channels. Adapting the facility to manage both means additional documentation, batch segregation, and ongoing operator training. Over the years, periodic audits from domestic and international regulators have helped sharpen our compliance mindset. By opening facility doors to third-party inspection and third-party analytical checks, we bolster trust in our batch records and quality claims.

    Paperwork does matter because it proves that process control isn't just a slogan but a day-to-day practice. Maintaining transparency with every order and shipping with full documentation gives end users and partners a reliable snapshot of the batch’s journey. Quality management means capturing lessons from every deviation—forging continuous improvement, not just ticking boxes.

    Differences That Matter: Hydrocholine Tartrate vs. Alternatives

    In our experience, the choice between hydrocholine tartrate and other choline sources boils down to more than spec sheets. Feed manufacturers working with choline chloride sometimes struggle with caking during transportation. Our hydrocholine tartrate, due to reduced hygroscopicity, means fewer complaints and easier discharge from silos. On the supplement side, formulators working with choline bitartrate have returned with feedback about dustiness and taste—compromises solved through hydrocholine tartrate’s milder profile and denser granule form.

    Pharmaceutical partners highlight lower levels of mono- and di-tartrate contaminants in our standard HTT-99 batches compared to alternative materials. This isn’t by accident, but the result of repeated, controlled purification and steady in-process monitoring. Several buyers note reduced reprocessing time when switching from material supplied by outsourcing intermediaries to our in-house product, saving both cost and rework.

    No batch leaves the facility without full tracking. From sourcing, through production, purification, drying, and packaging, the chain of custody assures accountability at every stage. Working this way means fewer surprises in downstream application, better cooperation with partners, and fewer interruptions caused by unexpected product performance.

    Final Thoughts From the Line

    There’s a long list of details bound up in a drum of hydrocholine tartrate, from the chemical specs down to texture, taste, and stability. Clean, hands-on manufacturing continues to shape every lot. Years of small and large improvements stack up, driven by hearing back from the people who use our product—not just reading test results, but learning from field and production floor experiences. It’s this cycle of observation, listening, and adapting that keeps us moving. Each drum carries the fingerprints of everyone working the process, and every improvement ties back to something learned and put into practice.

    As manufacturers, we don’t see hydrocholine tartrate as a commodity pulled off a shelf, but a carefully made product that reflects the sum of expertise, feedback, and a willingness to tackle whatever challenge the next batch brings. With continued attention, a close partnership with users, and an eye on both quality and impact, we see more ways to improve ahead. Our production floor keeps the process rooted in experience and open to adaptation—delivering hydrocholine tartrate as more than a chemical, but as the product of real-world learning and refinement.