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HS Code |
598154 |
| Name | Hesperidin |
| Chemical Formula | C28H34O15 |
| Molecular Weight | 610.57 g/mol |
| Appearance | Yellow to light brown powder |
| Solubility | Slightly soluble in water, soluble in alcohol |
| Source | Citrus fruits, especially oranges and lemons |
| Cas Number | 520-26-3 |
| Melting Point | 258-262°C |
| Purity | Typically ≥ 90% |
| Uses | Dietary supplement, pharmaceutical ingredient |
| Storage Conditions | Store in a cool, dry place away from light |
| Synonyms | Citrus bioflavonoid, Hesperitin-7-rutinoside |
As an accredited Hesperidin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Hesperidin is packaged in a sealed, amber glass bottle containing 100 grams, with a clearly labeled product name, batch number, and expiry date. |
| Shipping | Hesperidin is shipped in tightly sealed containers, protected from light, moisture, and extreme temperatures. Packaging complies with applicable regulations, ensuring safety during transport. Proper labeling, including the chemical name and handling instructions, is included. It is typically shipped as a powder and classified as non-hazardous under normal shipping conditions. |
| Storage | Hesperidin should be stored in a tightly closed container, kept in a cool, dry, and well-ventilated area, away from direct sunlight and sources of moisture. Recommended storage temperature is below 25°C (77°F). Protect the compound from incompatible substances such as strong oxidizing agents. Always follow local regulations and safety guidelines for chemical storage to ensure stability and prevent degradation. |
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Purity 98%: Hesperidin Purity 98% is used in pharmaceutical formulations, where it enhances bioavailability and efficacy in vascular protection. Molecular weight 610.56 g/mol: Hesperidin Molecular weight 610.56 g/mol is used in nutraceutical supplements, where it supports consistent dosing and predictable antioxidant activity. Particle size <50 μm: Hesperidin Particle size <50 μm is used in cosmetic creams, where it improves topical absorption and delivers uniform skin tone benefits. Melting point 258–262°C: Hesperidin Melting point 258–262°C is used in food fortification, where it ensures stability during thermal processing. Stability temperature up to 80°C: Hesperidin Stability temperature up to 80°C is used in beverage enhancement, where it maintains antioxidant capacity after pasteurization. Water solubility <0.01 mg/mL: Hesperidin Water solubility <0.01 mg/mL is used in sustained-release tablets, where it provides prolonged release and controlled therapeutic action. UV absorbance 283 nm: Hesperidin UV absorbance 283 nm is used in analytical quality control, where it allows accurate quantification and batch consistency verification. Residual solvent <0.01%: Hesperidin Residual solvent <0.01% is used in injectable formulations, where it lowers toxicity risks and complies with pharmaceutical safety standards. Heavy metals <10 ppm: Hesperidin Heavy metals <10 ppm is used in dietary supplements, where it ensures consumer safety and meets international regulatory requirements. pH stability range 4–7: Hesperidin pH stability range 4–7 is used in oral liquid medicines, where it preserves its efficacy during storage and administration. |
Competitive Hesperidin prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.
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Tel: +8615371019725
Email: admin@sinochem-nanjing.com
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Our journey in manufacturing Hesperidin stretches over a decade, and every batch carries a story of careful extraction and dedicated refinement. Hesperidin comes from citrus fruits, mainly bitter oranges. These peels contain high concentrations of the flavonoid, but not every extraction method delivers the same quality. Our production facility uses selective extraction, skipping through unreliable shortcuts. We take special care in the purification stage to get a consistent, high-grade powder. This hands-on approach removes bitter residues and unwanted byproducts that can affect usability downstream.
On the production line, Hesperidin stands apart from the crowd of other flavonoids. Some products advertise themselves as “citrus bioflavonoids complex,” but they frequently contain a vague blend where Hesperidin makes up only a tiny fraction. By focusing production on pure Hesperidin, our customers notice steady results in their formulations. Technicians here pay attention to the final composition, especially the water content and degree of crystallinity. This care shows during formulation, where consistency in particle size and chemical purity saves time and rework.
As a chemical manufacturer, our goal has never been to flood the market with variants no one needs. Instead, we focus on a refined specification fit for both research and finished product manufacture. Our main model offers Hesperidin at a typical purity of over 95%. Samples pulled from our most recent lots run between 96% and 98.5% purity by high-performance liquid chromatography, with residual solvents below reportable thresholds under current regulatory standards. Moisture by Karl Fischer titration typically sits under 5%, meeting the requirements for extended storage and milling.
The particle size we supply is engineered for optimal dissolution in aqueous and alcoholic solutions. Measured laser diffraction profiles report D50 values in the range of 50 to 80 microns, striking a good balance for bulk flow and blending. No excessive milling, no fluffy ultrafine dust, just a solid middle ground suitable for conventional blending or direct compression in nutraceutical applications. Color remains a reliable pale yellow, with no browning or residual peel fragments.
In practice, Hesperidin fills different needs across sectors. The largest share goes into dietary supplements, where standardized citrus bioactives are in high demand. We started batch production in response to specific requests from formulators frustrated by the inconsistency of imported grades that regularly deviated from spec, sometimes by as much as 20%. By sticking to tighter QC benchmarks, our Hesperidin allows supplement manufacturers to label their products with confidence and reduces their risk of regulatory retesting.
The next tier of clients come from the food and beverage industry. Some companies manufacture health drinks and fortified bars where bitterness control is critical. We frequently run pilot batches with product developers who want to adjust flavor profiles. By dialing in the purity and keeping off-flavors at bay, our product’s impact on taste is measurable, always within the range that finished goods developers find acceptable.
R&D labs from universities and pharmaceutical companies represent another set of customers. Research teams tend to analyze everything in their incoming materials, from chromatographic purity to trace pesticides. Transparency is key here, so we back every commercial lot with third-party assay data and provide unrestricted samples for pre-production trials. We know researchers sometimes get stuck when their test results don’t match supplier claims, so we keep every lot's certificate aligned with their needs, whether they’re investigating antioxidant properties, vasoprotective effects, or advanced delivery systems.
Plenty of products crowd the market under the flavonoid umbrella, but not all are created equal. Small differences in preparation technique matter in high-volume production. Our real-world experience shows that off-spec Hesperidin can cause filtration problems and won’t always dissolve as needed, clogging filters or leaving residue. We drew up our current process after seeing far too many jams in downstream equipment. Today, our plant lines use only stainless, closed reactors monitored with online turbidity and pH meters. These changes didn’t come overnight but stemmed from definite frustration with regrinding misshapen lots.
Pure Hesperidin also offers a different solubility and stability profile compared to mixed-content flavonoid extracts. Food-grade “bioflavonoid complex” ingredients often include sinensetin, naringin, diosmin, and other closely related molecules. That diversity comes with unpredictable taste, odor, and dissolution rates, making recipe adjustments more challenging and testing time longer. Our product skips those hurdles, sidestepping the masking agents or additional flavor tweaks that slow development cycles.
To keep consistency batch after batch, we maintain chromatographic fingerprints for each lot. Peaks that wander or background fluorescence signal potential impurities, immediately flagged for investigation before any drums go out. Control this tightly enough, and we lower customer returns and replace “problem batches” with real accountability.
Hesperidin buyers often assume every drum marked “pure” will perform as labeled. In manufacturing, we see the cracks that emerge without strict raw material and process controls. Too often, customers have shared samples of “premium” Hesperidin from resellers, only to discover it’s been cut with up to 20% maltodextrin, silica, or unidentified excipients. These fillers lower production cost for importers but compromise the reliability of finished products. We built our brand by refusing to dilute, supplying straight Hesperidin, no bulking agents, nothing to hide flaws or stretch a batch.
We’ve worked with customers who spent months recalibrating equipment to deal with brown, clumpy material that failed sieve tests. With every load-out from our facility, we guarantee batch traceability down to the exact shipment, keeping warehouses clear of mixed content risk.
We don’t just trust certificate of analysis paperwork. Every pallet receives HPLC checks for both purity and degradation products. Environmental monitoring in our lines tracks airborne solvent levels and particulate matter. By investing in updated instrumentation, we keep numbers reproducible and reduce personnel exposure to volatile solvents.
We’ve heard directly from customers who switched to our Hesperidin and saw blending times reduced by up to 30% in encapsulation machines. This result comes from uniform particle sizing rather than random fines and oversized flakes mixed together. Supplement producers report marked improvements in label claim assurance and pass rates during GMP audits. Our core lab data consistently show lot-to-lot variation no higher than 2%, making future blends predictable.
As regulations tighten worldwide, we keep up with applicable standards. Third-party audits run regularly, checking for pesticide residues, heavy metals, and microbiological contamination. Our Hesperidin complies with specifications found in the European Pharmacopoeia and typical requirements in the United States and Asia. Every customer can trace a single drum or bag back to the exact production run. When strict kosher and halal certifications are required, our lines offer segregated process time and cleaning verification.
Going green matters for many sectors. Our latest extraction revision replaced high-organic solvent washes with water-based clarification, cutting total volatile organic compound emissions by nearly 40% over the last two years. Operator safety improved, and no downstream residues cloud filtration.
Hard-won experience showed us the difference between chemically pure Hesperidin and mixed-flavonoid “bioactive blends.” Companies relying on bulk powders often come to us after failed attempts to work with cheaper grades that underperform. Picture the difference between a clear and completely dissolved solution versus an opaque, gritty suspension in actual beverage or tablet manufacture. A clean product removes those headaches.
Sourcing from a direct manufacturer removes delays linked to middleman communications, erratic lot tracking, or storage conditions that degrade product before it even lands at your facility. Temperature excursions and humidity can wreck a shipment long before use, and we learned to control for this by keeping all packaging moisture-tight and lot-coded.
We’ve hosted industry consortia who tour our facility and see the audit trails we maintain. Transparency isn’t a catchword here: every customer gets access to COA data, pilot lot history, and supporting spectral and chromatographic evidence. If requirements change or regulatory submissions demand even tighter data, we open the full set of manufacturing records up to review.
As manufacturers, we can’t ignore waste streams and environmental footprint. Years ago, some facilities dumped peel waste without a second thought. Now, our solvent recovery units process spent extraction liquor, recapturing 80% of usable solvent and sending the rest for offsite treatment. Peel waste is processed for limonene recovery or composted. Our water usage dropped 25% with the new closed-loop system, and we keep working to lower it further.
We adapted to new filtration technologies, moving from open plate-and-frame rigs to sealed, automated lines. Fewer manual interventions means fewer contamination risks and tighter batch control. This keeps microbial counts low and workers safe from exposure.
End users worry about trace contamination, especially with growing scrutiny from global regulators. Regular third-party checks for pesticides and solvent residues remain standard. We hold backup samples from every lot for two years in case customers need retest data later.
Shipping can be another hidden challenge. Extreme temperatures and high humidity during container transport lead to lumping or hydrolysis issues. By vacuum-sealing our double-layered packaging and using desiccant packets sized for each container, we sidestep these risks, and customer labs report clean results on intake.
Production downtime and reliability form another concern. The repeatability of material handling matters more than minor cost differences, as operators notice if a batch “runs hot” or “sticks” in their own feeders. Our philosophy centers on stable feed properties and honest specifications, not pushing boundaries at the expense of process uptime.
Customer dialogue drives much of our process innovation. Our technical service department keeps logs of recurring field complaints or unexpected test outcomes. We run root cause analysis on every valid issue, using actual field data to refine granulation or drying settings. This direct feedback has led us to fine-tune our particle size targets and prevent the dust clouds that used to slow down fill line operators in winter.
We regularly support product reformulation trials. If a sports nutrition customer wants a more readily dispersible form, our R&D handles co-processing runs and provides additional physical characterization. We share every result, positive or negative, because long-term trust hinges on collaborative problem-solving, not hiding behind silence.
Expectations don’t stand still, and neither can production standards. With more research focusing on functional foods and advanced delivery systems, we’re already piloting micronized variants for better dispersion in aqueous systems. Our goal is to match evolving industry requirements with process adaptability, not just external compliance.
Direct manufacturing provides the flexibility to launch tailored batches quickly. If a pharma client needs GMP-sterilized packaging or tighter control over specific impurities, our multi-line facility delivers. Our lot management database keeps full transparency, linking raw material acceptance, batch blending, and all QC data.
Buyers sometimes overlook the real difference between sourcing Hesperidin from a manufacturing source and dealing with resellers. Direct supply means consistent product, full batch traceability, and a guaranteed chain of custody. Questions about sustainability, purity, contamination risk, and supply security are answered directly rather than pushed off to a faceless “vendor partner.” Our connections to growers, raw material handlers, and shipping partners let us anticipate shortages and adjust order cycles.
Oversight means more than checking paperwork. Facility visits are encouraged. We welcome technical audits and share real manufacturing records, not sanitized summaries. This approach builds trust and delivers reliable Hesperidin, batch after batch.
As demand for Hesperidin grows, cutting corners brings only short-term profit. We keep every step visible, from supplier audits to final QC. Customers feel the difference directly in ease of use, finished product quality, and regulatory compliance. Not every supplier can say the same. Our team’s experience, investments in plant upgrades, and partnership with clients keeps us at the sharp end of the industry. Hesperidin is more than another commodity—done right, it’s a building block for reliability and honest results.