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Epigoitrin

    • Product Name Epigoitrin
    • Alias alkaloid E
    • Einecs 210-058-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    894227

    Name Epigoitrin
    Chemical Formula C5H7NO4S
    Molecular Weight 177.18 g/mol
    Iupac Name (2R)-2-amino-3-(2-carbamoylsulfanyl-1-hydroxyethyl)propanoic acid
    Appearance White to off-white crystalline powder
    Source Isolated from Isatis indigotica (Chinese woad)
    Mechanism Of Action Thyroid peroxidase inhibitor
    Applications Used in the treatment of goiter
    Solubility Soluble in water
    Melting Point Over 200°C (decomposes)
    Cas Number 6859-01-4
    Category Alkaloid
    Storage Conditions Keep in a cool, dry place
    Synonyms α-epithioglucose, (R)-epigoitrin
    Stability Stable under recommended conditions

    As an accredited Epigoitrin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Epigoitrin is supplied in a 25g amber glass bottle, sealed with a screw cap, labeled with product details and safety information.
    Shipping Epigoitrin is shipped in tightly sealed containers under cool, dry conditions to preserve its stability and prevent contamination. Protective packaging ensures safe transport, compliant with relevant chemical regulations. Handling guidelines and safety data sheets accompany the shipment, and expedited or temperature-controlled shipping is available upon request for sensitive research applications.
    Storage Epigoitrin should be stored in a tightly sealed container away from light, moisture, and heat. Keep it at room temperature, ideally between 2°C and 8°C (refrigerated), and in a well-ventilated, dry area. Ensure the chemical is labeled and kept separate from incompatible substances. Store out of reach of unauthorized personnel and follow all relevant safety guidelines.
    Application of Epigoitrin

    Purity 98%: Epigoitrin with 98% purity is used in pharmaceutical intermediate synthesis, where it ensures high yield and consistent active compound quality.

    Particle Size <10 µm: Epigoitrin with particle size below 10 micrometers is used in tablet formulation, where it enhances dissolution rate and bioavailability.

    Stability Temperature 40°C: Epigoitrin stable at 40°C is used in tropical climate drug production, where it maintains molecular integrity and extends product shelf life.

    Molecular Weight 160.17 g/mol: Epigoitrin with molecular weight 160.17 g/mol is used in metabolic pathway studies, where it allows for accurate traceability and characterization.

    Melting Point 145°C: Epigoitrin with a melting point of 145°C is used in solid dosage formulation, where it supports uniform mixing and thermal processing.

    HPLC Assay ≥99%: Epigoitrin with HPLC assay not less than 99% is used in analytical reference standards, where it provides precise quantification and quality control.

    Water Solubility 20 mg/mL: Epigoitrin with water solubility of 20 mg/mL is used in injectable solution preparation, where it ensures rapid compound dispersion and therapeutic effectiveness.

    Residual Solvent <0.1%: Epigoitrin with residual solvent below 0.1% is used in clinical formulation, where it minimizes toxicity risks and complies with safety regulations.

    Optical Rotation +18° (c=1, H2O): Epigoitrin with optical rotation of +18° in aqueous solution is used in enantiomer purity testing, where it confirms chiral integrity and pharmacological activity.

    pH Stability Range 4-8: Epigoitrin with pH stability between 4 and 8 is used in oral suspension development, where it ensures chemical stability and therapeutic reliability.

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    Certification & Compliance
    More Introduction

    Epigoitrin: A Closer Look from the Manufacturer’s Perspective

    Introduction to Epigoitrin

    Epigoitrin has become recognized among researchers and manufacturers who handle specialized chemicals, and its performance continues to encourage innovation in both pharmaceutical and botanical applications. In our experience manufacturing Epigoitrin, we have seen strong demand from companies looking to harness its unique structure, especially in relation to its sulfur-containing properties. Epigoitrin stands apart among alkaloids for its presence in certain Brassicaceae species, primarily Isatis indigotica—valued in the traditional medicine field. Our focus on high-purity crystalline Epigoitrin with a molecular formula of C5H7NO4S means consistent, reliable batches that support research, formulation, and testing. Competing products such as goitrin or common glucosinolates lack some of Epigoitrin’s nuanced benefits and stability profiles, which we have observed firsthand through comparative batch trials and production scale-up.

    Tracing the Source and Rationale

    Epigoitrin emerges from our in-house extraction process using native Isatis indigotica roots. Such botanical sources are not interchangeable, and our process development chemists regularly analyze fluctuations in raw plant materials. By controlling the duration and temperature of extraction and refining repeatedly, we help reduce any unwanted side products. This hands-on monitoring cannot be matched by bulk repackagers, as our chemical engineers and QC teams test for specific isomeric forms and maintain records for every lot. As a direct manufacturer, we’re often asked why Epigoitrin attracts interest relative to structurally related compounds. End users report that its configuration, with a thiazolidine core fused to oxazolidine, enables notable chemical stability even under light processing stresses. Other molecules isolated from the same plant sources lack this resistance to mild hydrolysis or oxidation, causing researchers extra effort during purification or storage. Our own work with stability chambers confirms that crystalline Epigoitrin, once isolated to our standards, holds up without significant degradation for extended periods.

    Model, Specifications, and Batch Integrity

    Rather than market a wide array of grades, we concentrate efforts on one standard: high-purity Epigoitrin produced as a fine, white crystalline powder. Over the years, we refined our crystallization techniques to consistently reach purity levels above 98 percent by HPLC. Some competitors, in an effort to produce larger volumes, sacrifice this level of selectivity; their samples often show faint yellow hues or minor byproducts upon analysis. Committed to quality, we maintain tight control over moisture content and residual solvent levels. This dedication comes from direct experience troubleshooting customer questions tied to inconsistent material properties such as variable solubility or batch-to-batch yield losses. Precision in our process helps avoid these pitfalls and streamlines formulation steps for our customers—whether they’re using Epigoitrin in analytical standards, functional verification, or scaling up intermediates for synthesis.

    Practical Usage: Insights Gained on the Production Floor

    We see the reality of Epigoitrin’s value every time a project scales from pilot to full production. Research institutions often begin with milligram quantities, but our facility routinely handles multi-kilogram synthesis. While some assume all thiazolidine derivatives behave similarly in downstream processes, our hands-on work says otherwise. For example, Epigoitrin's slightly higher melting point—averaging 143°C to 146°C—prevents unwanted fusion or sticky agglomerates during storage or transport. This property goes unnoticed until a material unexpectedly cakes up mid-process, causing a shutdown or failed run. Maintaining clean filtration and drying procedures ensures users do not face these problems. Our dryers, fitted with fine mesh screens, remove excess moisture without thermally stressing the crystals, and our packing line inspects each jar for signs of premature clumping or contamination. Simple details such as these make the difference between smooth operations and recurring headaches for end users.

    Real-World Benefits for R&D and Formulation

    Working directly with research partners, we learned that Epigoitrin’s greatest contribution lies in its predictability for analytical and formulation studies. Chemists studying anti-viral or anti-inflammatory activities look for clean standards with tightly defined purity and impurity profiles—qualities we emphasize at every production run. Reports from collaborating labs indicate that Epigoitrin’s spectral signatures along NMR, IR, and mass spectrometry offer less background noise than less-refined analogues, which simplifies data interpretation. When pharmaceutical teams need milligram-to-gram batches for preclinical studies, we accommodate special requests for documentation and traceability, submitting full analysis sheets and lot histories. By collecting systemic feedback from chemists and analysts who put Epigoitrin to work across multiple in vitro and in vivo models, we keep our own operational protocols aligned with actual needs, not just theoretical product guidelines.

    Field Comparisons: Differentiation from Similar Alkaloids

    Not all alkaloidal sulfur compounds serve the same role in formulation or research. As a sulfur- and nitrogen-containing molecule, Epigoitrin distinguishes itself from close relatives such as progoitrin, goitrin, and common glucosinolates found in the same botanical families. Goitrin, for example, contains an epithio ring that reacts differently under pH changes and heating, leading to variable assay results or breakdown products. Our R&D group has run side-by-side dissolution and recovery studies to map these differences, discovering that Epigoitrin consistently yields more reproducible results for anti-viral screening and biochemical analysis. Differences in logistical handling also come into play. Customers using progoitrin derivatives from general suppliers often complain about instability in liquid preparations, but our Epigoitrin powder, due to its specific microcrystal morphology, disperses evenly for rapid assay setup without extra sonication or solubilizer additions.

    Manufacturing Practices Centered on Safety

    Years of experience refining safety protocols in our Epigoitrin facility have taught us to anticipate both common and uncommon hazards associated with sulfur-heterocycle chemistry. Hands-on training and real-world incidents highlight risks from airborne dust or inadvertent cross-contamination. Our process chemists and QA experts regularly recalibrate environmental controls and review PPE usage. These aren’t just precautionary measures; effective dust control and segregated workflow zones keep contaminants from affecting other plant processes, particularly since Epigoitrin’s thiazolidine skeleton can react with certain heavy metals or strong oxidants. Our audits focus not only on product safety but also ensuring no cross-over with unrelated APIs or botanicals processed in the same plant. All operators run through simulated emergency drills based on realistic scenarios—avoiding theoretical paperwork in favor of genuine preparedness, a mindset that supports confidence from our customers.

    Common Questions and Technical Guidance

    In our conversations with industry partners, certain technical issues come up repeatedly. Researchers new to Epigoitrin sometimes wonder about its solubility parameters. Direct measurement shows easy dissolution in water at room temperature, an advantage over structurally similar alkaloids that only dissolve in strongly acidic or basic media. Technicians often call to ask about Epigoitrin’s photostability during open-vessel work; we recommend standard lab practices such as working in amber glassware under subdued lighting, based on stability screening done by our QC group across several product lots. More seasoned users, scaling up from gram batches to kilogram demand, want to avoid caking problems and know our packaging team runs compaction index checks on all finished powder lots. We often walk through storage and handling best practices—like maintaining climate-controlled environments at 2-8°C—to eliminate performance issues in live runs.

    Choosing Epigoitrin Over Bulk Alternatives

    Epigoitrin’s specialty roles make it more than just a plant extract. Over the years, we’ve worked with product developers seeking consistent assay controls, advanced phytochemical processing, and medicinal chemistry research. They rarely find the reliability by sourcing from generic bulk extract suppliers. Piggybacking quality by relying on a trader’s upstream processes often leaves customers with contaminated or poorly documented materials. We push for direct supply lines that cut through the fog of repackaged extracts, instead offering detailed certificates of analysis and supporting documents tied to each batch. Not every competitor regularly monitors batch-by-batch variance against industry reference standards, but we keep that as a core element of quality assurance. Companies demanding credibility—especially for regulated studies or clinical endpoints—turn to direct manufacturers who manage the whole process under one roof, from raw root chopping to final seal on each powder jar.

    What Sets Epigoitrin Apart for Your Team?

    Direct feedback from research teams signals that Epigoitrin thrives in part due to our ability to guarantee traceability and product uniformity. Pharmaceutical and academic researchers depend on batch consistency, and anecdotal accounts abound of project setbacks caused by unexpected ingredient drift. Our chemists field regular questions about whether Epigoitrin and its isomers impact experiment reproducibility. Performing in-house NMR and mass spectrometry tests safeguards against outliers and allows us to spot any deviation before product release. For analytical chemistry applications, our material’s defined melting range, color, and flowability simplify laboratory scale-up and automation. Experienced formulators cite fewer compatibility or sedimentation issues, which reduces investigation time and rework. This collection of advantages doesn’t come from luck, but rather ongoing investment in cleanrooms, analytical instrumentation, and documented know-how that grows every production cycle.

    Feedback Loop: Working Directly With End Users

    Over the years, we built close partnerships with both industrial and academic clients by taking complaints and suggestions seriously. Chemists testing Epigoitrin for bioactivity screening sometimes identify subtle points, such as interference from trace plant metabolites or microbial contaminants. These raised the bar for how we process and purify successive lots. Clinical research groups who encountered failed batch certifications with non-manufacturer suppliers tell us direct communication eliminates delays and translation errors in test documentation. By being present in the development pipeline—rather than hands-off like a distributor—we introduce process changes that anticipate future market and regulatory demands. These relationships help us keep internal SOPs up-to-date and maintain our position as a trusted source for Epigoitrin, whether the batch is destined for a benchtop, pilot reactor, or clinical protocol.

    Addressing Shelf Life and Storage Questions

    Our experience with long-term storage continues to influence our shipment and post-shipment support. Once, a client storing a bulk lot above recommended temperatures reported color shifts and reduced assay values; this feedback prompted a review of our secondary pack materials, leading us to select food-grade HDPE with tighter barrier properties and double-seal lines. Each product shipment now includes a stability summary based on real-world shelf-life data, not theoretical numbers. Customers with challenging delivery routes or variable climate control appreciate these efforts, as it eliminates wasted time and resources tracking down root causes for performance failures. Simply put, good chemical manufacturing practice extends beyond the process plant—batch traceability, robust packaging, and active technical support all play a role in keeping Epigoitrin effective whenever and wherever it’s needed.

    Supporting Advanced Analytical and Synthetic Work

    Analytical labs use Epigoitrin for multiple assay development protocols, where peak clarity in chromatograms determines the efficiency of the process. The meticulous purification in our process repeatedly demonstrates sharper, more isolated peaks with significantly cleaner baselines than materials sourced from open markets. Synthetic chemists scaling up analogues value predictable crystallization behavior and high melting stability, avoiding the unpredictable polymorphism or hidden impurities that often derail synthesis runs. In pilot synthesis, Epigoitrin's reactivity towards nucleophiles remains consistent, as verified by our years of kinetic profiling and batch simulations. By investing in this level of technical support, we help chemists optimize downstream derivatization and purification—acting as a real partner in R&D beyond providing a standard off-the-shelf chemical.

    Continuous Improvement and Customer Education

    Our long-term success with Epigoitrin rests on openness to customer feedback and a culture of ongoing process review. We host training sessions and technical Q&As with purchasing, R&D, and QC teams so users understand not just the theory but also the real-world variables that matter when using Epigoitrin in demanding environments. These educational efforts have a practical impact—improved experiment reproducibility, safer handling in scale-up settings, and a more accurate view of how Epigoitrin fits into complex workflows. Users new to the compound often reach out for best practices on integrating Epigoitrin into existing active ingredient libraries; we walk through compatibility, solvent screening, and potential scale-up bottlenecks. Our role as a manufacturer means not just delivering chemical at the dock, but supporting our customers through the entire project lifecycle, from pilot sampling to finished research or market-ready outcomes.

    Outlook: Meeting Tomorrow’s Demand with Confidence

    The landscape for Epigoitrin continues to change, with evolving research priorities and stricter expectations for pharmaceutical supply chains. By focusing on in-house production—from raw plant sourcing through controlled synthesis and finishing—we reduce risk, improve reliability, and support timely delivery. Direct dialogue with research innovators keeps our processes nimble and ensures that our Epigoitrin keeps pace with new scientific needs. Technological improvements, expanding analytical instrumentation, and growing regulatory awareness challenge us to improve, not rest on past success. It’s this ongoing commitment to transparency, accurate documentation, and technical partnership that sets our Epigoitrin apart—and gives our partners a reliable foundation for their most important work.

    Closing Thoughts on Choosing Epigoitrin from a Direct Source

    As manufacturers, we bring a level of technical involvement that goes far beyond what resellers or generic suppliers can offer. Years spent refining extraction, crystallization, and QA protocols have led us to a product that consistently meets the expectations of demanding chemists and developers. Every batch of Epigoitrin reflects careful plant selection, in-process monitoring, and rigorous documentation. The result is a chemical that does what it should—whether in pharmaceutical discovery, functional food ingredient screening, or natural product synthesis. By keeping production under one roof and building relationships with end-users, we provide real-world advantages that bulk commodity players can’t touch. Our role doesn’t end with shipment; ongoing customer education, technical dialogue, and responsive post-sales support ensure that our Epigoitrin delivers where and when it counts most for your team and your research goals.