Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Dl-Serine

    • Product Name Dl-Serine
    • Alias DL-2-Amino-3-hydroxypropionic acid
    • Einecs 200-522-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    224561

    Chemical Name DL-Serine
    Molecular Formula C3H7NO3
    Molar Mass 105.09 g/mol
    Cas Number 302-84-1
    Appearance White crystalline powder
    Solubility In Water Freely soluble
    Melting Point 222-226°C (decomposes)
    Ph Value 5.5-7.0 (1% solution)
    Optical Activity Racemic (no optical rotation)
    Storage Conditions Store in a cool, dry place
    Synonyms DL-2-Amino-3-hydroxypropionic acid
    Stability Stable under recommended conditions
    Uses Biochemical research, laboratory reagent
    Odor Odorless
    Hazard Statements Generally regarded as non-hazardous

    As an accredited Dl-Serine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed, high-density polyethylene bottle labeled "DL-Serine, 100g", featuring hazard symbols, batch number, and storage instructions.
    Shipping DL-Serine is shipped in tightly sealed containers to protect it from moisture and contamination. During transport, it should be kept in a cool, dry place, away from incompatible substances. Standard chemical shipping regulations apply, and appropriate hazard labels are affixed as per international and local guidelines.
    Storage DL-Serine should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from direct sunlight and moisture. It is advisable to keep it at room temperature and separate from incompatible substances, such as strong oxidizers. Store DL-Serine according to standard laboratory chemical storage practices to maintain its stability and prevent contamination or degradation.
    Application of Dl-Serine

    Purity 99%: Dl-Serine with 99% purity is used in pharmaceutical synthesis, where it ensures high-yield production of chiral drug intermediates.

    Molecular weight 105.09 g/mol: Dl-Serine at 105.09 g/mol is utilized in biochemical research, where its standardized molecular profile allows precise metabolic pathway studies.

    Melting point 222°C: Dl-Serine with a melting point of 222°C is applied in peptide manufacturing, where it enables robust solid-phase synthesis under controlled heat conditions.

    Particle size < 100 μm: Dl-Serine with particle size less than 100 μm is used in nutritional supplement formulation, where it facilitates homogeneous blending and rapid dissolution.

    Stability temperature up to 40°C: Dl-Serine with stability up to 40°C is employed in diagnostic reagent production, where enhanced shelf-life under ambient conditions improves logistics efficiency.

    Water solubility 7.5 g/100 ml: Dl-Serine with water solubility of 7.5 g/100 ml is used in cell culture media preparation, where it ensures rapid and complete bioavailability for cellular uptake.

    Optical rotation (neutral): Dl-Serine with neutral optical rotation is used in racemic mixture studies, where unbiased stereochemical reactions are required for analytical calibration.

    Heavy metal content < 10 ppm: Dl-Serine with heavy metal content below 10 ppm is utilized in high-purity enzyme production, where minimized contamination assures enzyme activity consistency.

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    Certification & Compliance
    More Introduction

    Dl-Serine: Reliable Supply from the Manufacturer's Perspective

    Production Approach and Experience

    Every batch of Dl-Serine we produce comes from the same plant lines that we’ve developed and run, not only for years, but across shifting market demands and tighter end-user quality expectations. Over time, the decision to refine our methods didn’t come from market brochures or hypothetical needs—it came from busy production teams tracking costs, dealing with real customer feedback, and keeping up with audits. Our fermentation and synthesis routes each have their fans; the consistency shoppers usually talk about rests on what happens after that: careful separation, monitored crystallization, robust drying, and methodical packaging. Staff including senior technicians and long-time shift workers run the tightest QC checkpoints for each grade: technical, food, or pharma. Every step comes with logs, spot checks, and conversation. That commitment shows up whether you order a few drums or set up rolling bulk delivery for months ahead.

    Dl-Serine Model and Key Specifications

    Over years of direct manufacture, we’ve seen the strongest demand for Dl-Serine in fine crystalline powder form at purity levels not dipping below 98%. Particle size is measured tightly for customers working in tableting, capsule filling, or formulating blends, since it shows up early in batch-mixing and late in finished-product texture and solubility. Our powder flows well, making it adaptable for continuous processing setups, which saves time and helps prevent uneven mixing or bridging in hoppers. Our typical range for moisture keeps at less than 0.5%, resulting from regular batch predrying, oven checks, and confirmed weight loss on drying. Even packaging—usually double poly-lined fiber drums kept in clean storage—traces directly to audit checklists that come up in our own internal GMP reviews, not only during outside inspections.

    Understanding Authentic Dl-Serine Quality

    In the market, confusion sometimes arises from products labeled as “Dl-Serine” but showing inconsistent particle color, non-uniform clumping, or varying bulk density. These features may seem trivial at first pass, but any formulator using a repeatable process knows they create risks—especially for applications in supplements, cell culture, or pharmaceuticals. We see plenty of samples circulating that fail to reach advertised purity, or whose amino acid profiles, on closer examination, deviate from standard HPLC fingerprints. Our in-house tests flag any batch with impurities above specification long before any order leaves the plant. Transparency with customers starts with publishing regular batch COAs based on internal and third-party testing, with retention samples available for post-delivery questions.

    Difference from L-Serine and Other Amino Acids

    Dl-Serine stands apart from single-isomer L-Serine by nature of its racemic composition: chemically, each batch brings together D and L forms in a 1:1 ratio. In synthetic chemistry, lab work, and certain feed or fermentation processes, this difference matters. For customers who rely on only the biologically active L-form, racemic material doesn't fit. In other settings—particularly manufacturing, research, fermentation starter feed, and some diagnostics—customer processes exploit both optical forms or achieve target results independent of chirality. That’s why our production capacity always keeps the two lines separate, down to storage and labeling. By keeping supply chains untangled, customer businesses avoid cross-contamination and preserve the trust built over hundreds of repeat deliveries.

    Compared to glycine, alanine, or other non-polar amino acids, Dl-Serine brings a unique side group with its hydroxymethyl branch. This sets up a different solubility profile, distinct hydrogen bonding, and a reactivity that shows up in both solution-phase and solid-state applications. We see direct customer feedback noting how this enables everything from enhanced biomaterial research to the production of intermediates in specialty chemicals. Every year, we track batch retention and downstream results to update these chemical and application-specific properties.

    Common and Advanced Uses for Dl-Serine

    Customers choose Dl-Serine for an unusually wide set of uses. In our records, it supplies industries from animal nutrition (where both isomers play roles) to buffer systems in electrophoresis and analytical chemistry. Some research teams require racemic serine for enzyme substrate specificity or as a component in protein structure studies, while others need high-quality powder for microbiological media optimization. We help clients in nutritional supplement formulation; here, the demand may emerge for the D-form’s unique metabolic potential, which isn’t addressed by supplements limited to L-Serine.

    In chemical synthesis, peers reach out for racemic serine as a multipurpose building block, taking advantage of its two chiral centers for further transformation or as a protected intermediate. The list of customers includes makers of diagnostic kits, reagent suppliers, research labs optimizing synthetic routes, and sometimes teams working on scale-up for novel food or pharma-grade intermediates. Where customers need to understand which batch or process fits their equipment or protocols, our decades of scale-up and batch record data provides reference, troubleshooting, and process-matching information.

    Supply Assurance, Traceability, and Scalability

    Manufacturing Dl-Serine at the scale modern industry asks for involves a balancing act of transparency, equipment maintenance, and skilled team operations. Any batch can be traced through logs kept from raw starting materials, time-logged production operations, and stored sample retention vials—most still on-site from batches produced years ago. When global buyers—including European, American, and Asian firms—set up multiple quarterly deliveries, annual contracts, or apply for regulatory filings, they access not just the base product but also custom documentation, stability data, and support for audits.

    Adjusting supply for seasonal demand surges—such as those common in animal nutrition or research funding cycles—starts with raw material inventory planning months in advance. Process engineers coordinate with QA, blending technical improvements (like filtration upgrades or nitrogen-purged dryers) straight into the regular calendar of facility upgrades. Waste stream management and emissions control practices undergo review with each audit, improving with each feedback loop and active staff suggestions.

    Purity and Process—The Heart of Manufacturing Reputation

    A reputation built on technical repeatability gives customers confidence. We field regular queries about how Dl-Serine holds up under different storage conditions, what happens if containers go through temperature swings on the way to port, or how much batch-to-batch variation the user might expect in their downstream processing. Our regular temperature and moisture stress tests give straightforward backing to those conversations. If a material shipper finds a handling deviation at intake, our sample controls and documentation help identify and resolve the issue fast—with no finger-pointing or blame games needed.

    We’ve chosen to invest heavily in NMR, IR, and chromatographic fingerprinting, so even subtle differences caught during batch transition or raw material source changes show up early. These efforts, although resource-intensive, make a clear difference for customers moving from pilot to commercial scale. For supplement users, detail like this ensures label-level compliance and trace residue control. In life science research, reproducibility gained by stabilized, identical-looking powder batches turns into data reliability and research integrity.

    Logistics, Handling, and Customer-Side Challenges

    Dl-Serine powder, once filled and sealed, can pick up water from humid air if containers break seal or transit extends longer than planned. Real experience in loading docks and warehouses taught us to use double-sealed drums, scheduled fast transfers, and desiccant packs. Sometimes, despite the best effort, local storage rooms or warehouses can run into accidental spills or partial exposure. We work directly with distribution and end-users to provide handling, shelf-life, and in-use recommendations based on real-world case studies, not just theoretical “best practices.” Failure to adopt such prevention methods usually shows up as lumps, reduced flow, or—even worse—label error risk if final product composition drifts.

    Many inquiries each year come from end-users with legacy equipment or software designed for other grades or different manufacturers, sometimes even for L-Serine alone. Our technical team walks through process matching, whether that means specific blending speed adjustment, feeder retrofits, or packaging tweaks to adapt to automated dosing equipment. Both large and small buyers benefit from these manufacturer-side lessons, as adjustments on our line usually deliver bigger gains than late-stage workarounds in a customer’s facility.

    Customer Auditing and Meeting Regulatory Needs

    Being an actual manufacturer, not a middleman or third-party repacker, means that we frequently open our plant, records, and systems to customer audits. This includes major multinationals as well as dedicated regional buyers in sensitive markets. Our regulatory documentation starts long before the delivery truck arrives at the customer’s facility: traceability, supply chain mapping, staff training logs, and environmental performance records stay up to date and available for study at any time.

    In countries where food, pharma, or animal feed laws grow more advanced every year, our approach includes open data and customer-by-customer documentation matching to fit their regional requests. Adjustments for minor changes—say, a customer’s new specification for trace metals or isotopic labeling—go through a plant-level review, technical feasibility check, prototype production, and detailed documentation before ever hitting the standard order pipeline. Compliance doesn’t wait for regulators—it’s embedded in every continued customer partnership.

    Addressing Market and End-User Feedback

    It’s not rare for us to get direct calls or emails about uncommon technical challenges. Some researchers, for example, notice trouble when batch solubility in specific buffers shifts by tenths of a percent; others may find color changes with new packaging lines. People working in cell culture sometimes run experiments that catch issues invisible to basic analytical tests. We pull those learnings directly into our process review meetings.

    Feedback is not just a customer service slogan for us; it’s a direct lever for improvement in equipment choice, raw material selection, and runtime parameter tuning. Years ago, a major user flagged issues with product caking in high-humidity stores. After root cause review, we swapped out internal dryer configurations and packaging film specs, which reduced caking incidents for all subsequent lots. These outcomes appear in our tracking metrics, and—most important—the lessons stick with staff as they train new teammates.

    Comparing Dl-Serine with Other Market Options

    Customers sometimes ask: why work with a manufacturer like us, rather than a trader or repacker offering rebranded material from elsewhere? From over two decades of operating our own equipment, scaling batches, and closing the feedback loop with real industry partners, the answer points straight to control and transparency. Traders provide surface-level guarantees, but direct manufacturers know every stage of their material’s journey. Our records span from initial synthesis to the drum loaded on the shipping pallet; should an issue arise, root causes are identified and resolved by the same team, not outsourced across jurisdictions.

    We see real cases where middleman-supplied serine fails long-term storage or exhibits lot-to-lot instability. In those cases, customer downtime and paperwork burdens outweigh upfront dollar savings. Our commitment centers on building long-term partnerships—around technical strengths, steady supply, product security, and full problem-solving capacity.

    Commitment to Ongoing Improvement and Sustainability

    Manufacturing isn’t static, and neither are the demands of users who bring our Dl-Serine into their facilities and products. Market expectations rise, sustainability standards shift, and production efficiency gains turn into competitive advantage, not just for us but for our partners. In our own process, energy audits, waste stream optimization, and solvent recycling projects now tie directly to cost, compliance, and customer discussions. Our success in continuous emissions reductions over the last few years marked a win both for our carbon ledger and repeat buyers—especially those looking to feature sustainable sourcing on product packaging or procurement guidelines.

    No plant improvement delivers change as quickly as a motivated technical staff: shop-floor suggestions, trace impurity analytics, calibration upgrades, and better automation appear not just on annual plans but emerge at weekly staff meetings or following after-shift debriefs. This active approach, rooted in team experience, delivers not only better Dl-Serine but also clearer supply chain confidence for every partner relying on our product.

    Looking Ahead: How Customer Needs Drive Progress

    Years of manufacturing amino acids like Dl-Serine means adapting in step with the people using the product—from multinational research teams to nimble specialty start-ups. It means constant review: does our process actually match the user’s spec, or is there a better way to run filtration, improve drying, cut costs, or reduce packaging waste? We regularly ask tough questions: What support would really help a new customer integrating Dl-Serine at scale? Can our packaging or documentation get clearer? Is every optional impurity level mapped, tested, and documented so the toughest auditors don’t find weak spots later?

    That’s where the difference comes in: being the manufacturer, we don’t need to wait for third-party feedback or market push. We drive those upgrades ourselves, with every single batch, order, and customer call. Dl-Serine will keep evolving—just as our industry and its requirements do.