Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Daurinoline

    • Product Name Daurinoline
    • Alias Papaveraldine
    • Einecs 210-087-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    759412

    Product Name Daurinoline
    Chemical Formula C18H23NO3
    Molecular Weight 301.38 g/mol
    Iupac Name 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl(4-methoxyphenyl)methanone
    Cas Number 5610-84-2
    Appearance White to off-white crystalline powder
    Solubility Slightly soluble in water, soluble in organic solvents
    Melting Point 172-174°C
    Source Isolated from Menispermaceae family plants
    Pharmacological Activity Anticholinesterase and antiarrhythmic properties

    As an accredited Daurinoline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for Daurinoline consists of a sealed 100g amber glass bottle with a tamper-evident cap and detailed hazard labeling.
    Shipping Daurinoline should be shipped in tightly sealed containers, protected from light, moisture, and extreme temperatures. Use adequate cushioning and chemical-resistant packaging. Ensure compliance with local and international regulations, including proper labeling, documentation, and, if applicable, hazard classification. Handle with appropriate personal protective equipment and store in a cool, dry location during transit.
    Storage Daurinoline should be stored in a tightly sealed container, protected from light and moisture, in a cool, dry, and well-ventilated area. Store at room temperature and away from incompatible substances such as strong oxidizing agents. Ensure proper labeling and keep away from sources of ignition. Access should be limited to trained personnel following standard chemical storage protocols.
    Application of Daurinoline

    Purity 99%: Daurinoline with purity 99% is used in pharmaceutical synthesis, where it ensures consistent yield and high product quality.

    Viscosity Grade 500 cP: Daurinoline of viscosity grade 500 cP is used in controlled-release drug formulations, where it provides optimized release kinetics.

    Molecular Weight 320 Da: Daurinoline with a molecular weight of 320 Da is used in peptide conjugation reactions, where it allows precise molecular assembly.

    Melting Point 142°C: Daurinoline with melting point 142°C is utilized in thermally processed coatings, where it delivers stable film formation.

    Particle Size <10 μm: Daurinoline with particle size less than 10 μm is used in dermatological creams, where it improves uniform dispersion and absorption.

    Stability Temperature 80°C: Daurinoline stable up to 80°C is used in high-temperature polymerization, where it maintains reactivity without decomposition.

    Solubility 20 mg/mL in ethanol: Daurinoline with solubility of 20 mg/mL in ethanol is used in liquid drug delivery systems, where it enables homogenous active loading.

    Moisture Content <0.2%: Daurinoline with moisture content below 0.2% is employed in lyophilized pharmaceutical preparations, where it prevents hydrolytic degradation.

    pH Range 5.5–7.0: Daurinoline effective in pH range 5.5–7.0 is used in ophthalmic solutions, where it maintains ocular compatibility and product stability.

    Optical Purity >98% ee: Daurinoline with optical purity greater than 98% enantiomeric excess is employed in chiral drug synthesis, where it enhances stereospecific biological activity.

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    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Introducing Daurinoline: A Fresh Take from the Factory Floor

    Daurinoline doesn’t get the fanfare that more common compounds attract, but in the workshop and the lab space, we’ve seen its value come alive in repetitive, real-world trials. As the manufacturer responsible for every kilogram that leaves our facility, we know the story starts long before a finished batch rolls out the door. Daurinoline works as a dependable building block in several applications—pharmaceutical research, specialty intermediates, and advanced analytical processes, to name a few. We’ve designed our production at the model DA-405 standard, reflecting more than a decade of adjustments based on operator feedback and client field results. Decisions on particle size, crystalline purity, and total assay stem from chemists working directly on the line, not distant procurement desks.

    What Sets Daurinoline Apart in Today’s Chemical Landscape

    Manufacturing chemicals rarely leaves room for pretense. Daurinoline stands out because its molecular structure, shaped to tight tolerances, holds up under scrutiny by researchers and process engineers. The biggest difference comes down to purity and actionable consistency. Other products in the market tend to make headlines for their volume, but they leave users wrestling with deviation batch by batch. Through in-line controls and batch-by-batch chromatography readings, each DA-405 lot hits 99.2 percent assay, free flowing and low in residual solvents. There is no question about what chemists can expect—our product remains stable under standard ambient warehousing, and even after six months, analytical runs do not veer. Those who measure, synthesize, or scale processes on a daily basis count on this consistency to avoid recalibrating time and again.

    Some resellers or brokers pitch Daurinoline as generic white powder, promising everything and nothing at the same time. Direct from the factory, we know the story behind every batch, each blending adjustment, and every tweak to drying profiles. Our process does not lean on high throughput alone; our lead operators input their raw numbers from moisture analyzers, HPLC, and particle imaging just as much as company records or customer-facing specification sheets. When bottling for pharmaceuticals, this approach saves time and loss in pilot runs. When shipping kilos to specialty dye houses, it means the formulation process kicks off on day one without surprises.

    Practical Applications and Everyday Performance

    People working at research benches, pilot plant scale-ups, and even formulation lines see practical differences in how Daurinoline handles in dosing, dissolves in solution, or binds in matrices. On its own, Daurinoline supports both small molecule pathways and advanced material synthesis routines. In the context of pharmaceutical intermediates, our partners value the predictable melting range and moisture content, often less than 0.2 percent water weight by Karl Fischer titration. Even where others rely on visual cues or generic specs, our approach keeps measurements in mg/kg, and the results line up with downstream production needs.

    Lab management teams report fewer scheduling delays because our lots don’t bring unexpected particulates, stuck caking, or false negatives during purity tests. Blending lines don’t deal with abrasive fines or color shifts batch to batch. It takes real labor hours and a chemistry background to get here; each aspect of the process—filtration, vacuum drying, and post-synthesis fractionation—responds to real-time samples and technician experience, not just protocol. Field reports show Daurinoline supports extended shelf life, and respects expected shelf stability in routine storage, provided it’s kept sealed and away from direct dampness.

    Reliability—Not Just a Slogan, but a Log Book Requirement

    Manufacturing Daurinoline over multiple campaigns revealed patterns that data sheets alone don’t capture. Storage at the wrong humidity triggers slow degradation; excessive mechanical handling increases particle breakdown and complicates dosing, especially in automated fill systems. By tuning our drying step and updating packaging based on seasonal readings, we cut down on both in-plant waste and field batch returns. Clients report that their process yields benefit when input material doesn’t drift run by run. Our finished Daurinoline keeps analytical performance within a narrow variance window, especially on repeated tests for residual impurities or melting interval.

    For research and analytical groups, extra quality checks don’t slow down shipping schedules. Each lot gets logged through in-house chromatography before final drum sealing. More importantly, cross-verification between process shifts prevents deviations, so every QA step adds actual confidence. Reputed brands who purchase from brokers sometimes accept material that veers 2-3 percent in purity from one shipment to the next. Bench scientists end up troubleshooting recipe failures or out-of-spec results, losing hours over what should have been a straightforward project. Our factory approach trades the illusion of speed for proven, error-corrected workflow.

    Understanding the Differences That Matter in the Supply Chain

    Daurinoline, as we produce it, isn’t a “one bucket fits all” product. The model DA-405 emerged by attending to repeated pain points voiced by end users—lab clumping, invisible fine contamination, and irregular melting behavior caused by micro-impurities. Unlike broad-market alternatives, each DA-405 batch passes multiple hands-on evaluations before we clear it for distribution. Bulk customers see the evidence in less rework and more reliable lot traceability. The decision to build lots in modular reactor runs, rather than pushing oversized scale, maintains compositional uniformity and responds to actual demand cycles, with real flexibility for specialty orders.

    Field users in specialty pigment production point out color quality in their end goods is more stable when Daurinoline falls within strict melt spec and solubility drift is minimal. Analytics teams appreciate the absence of ambiguous side peaks in chromatographic screening. Formulators on pharma development teams reference cleaner downstream reactions and reduced sample rejection rates. It’s not about delivering an anonymous white powder; it’s about bridging the knowledge from handling bulk intermediates with feedback from every major application sector we serve.

    Direct-from-Factory Traceability and Real Transparency

    Unlike anonymous or white-label intermediates, Daurinoline DA-405 arrives with a direct trail back to our manufacturing line. Our records, operator logs, real-time environmental readings, and chemical batch profiles flow together in every shipment report. Customers see the lot’s story, including moisture readings, in-process adjustment logs, and finished purity analysis, not retroactive paperwork meant to check a box. Chemical manufacturing needs operational honesty; we offer this, because our staff stands behind each lot sent out.

    Raw materials present their own risks—trace contaminants, off-specification solvents, and storage exposures can compromise final batch characteristics far down the supply chain. That’s why each incoming raw stream gets tested independently of supplier documentation. Real feedback from our filling teams and process control engineers keeps batches on spec, even as global feedstock trends shift. Through local control, we keep unwanted variables out of our finished goods.

    By holding our process steps in-house—no third-party outsourcing, no off-shore “finishing” steps—each drum and each sampled packet directly reflects what we put in, what we refine, and what we approve. End users find reassurance knowing the source is accountable, the lot history is open to view, and support comes straight from the technicians who manage these processes daily.

    Why Daurinoline Isn’t Just a Commodity Chemical

    The market treats many intermediates as interchangeable. Any producer running generic specs and large reactors can crank out powder that passes visual and minimal purity checks. But formulation chemists, pilot plant managers, and scale-up engineers run into frustrations every day because that “commodity” approach hides instability, unpredictable residues, and headaches each time a formulation takes a wrong turn. Daurinoline DA-405 emerged to close this gap. Every parameter—melting point, residual solvent, trace catalyst content—reflects feedback from years of in-field troubleshooting, not just a generic spec list.

    Some alternatives, especially those sourced through bulk traders, land on the dock with data gaps and minimal accountability. That might seem enough for desk review, but in active formulation, flaws pop up: delayed reaction profiles, haze in end solutions, and false negatives on spectral analysis. Our approach focuses on eliminating these unknowns by backward-tracking all feedstock components and verifying during every step of our synthesis cycle. By focusing on granular transparency, reliability becomes real and measurable.

    Practical Handling and Storage: What End Users Should Know

    Having worked with hundreds of customers over many product cycles, we realize handling a specialty chemical can make or break daily operations. Daurinoline, as we send it out, resists ordinary clumping and handles dust in standard filling lines with modest extraction systems. Standard packaging involves layered barrier drums, foil seals, and tamper tags applied right at the close of final blending. We hold this packaging line right inside the main synthesis hall; cross-contamination never enters the picture since we do not run unrelated chemicals in the same suite.

    In transit, user teams continue to monitor conditions. Users in climates with seasonal temperature bands keep stock under sealed, dry warehousing, and our inclusion of logging chips in bulk containers gives ongoing feedback on conditions. Facility teams that do not have high-precision environmental controls rely on our moisture management at dispatch to bridge any gaps. Specialty orders with narrow particle range, tighter moisture band, or dedicated solvent wash pass internal QA checks tailored to destination requirements. Our in-house customer teams offer guidance rooted in first-hand experience, not middleman scripts or outside agency talking points.

    Experience and Support for Every Use Case

    As a manufacturer handling both pilot and large-scale requests, we see the full spectrum of challenges in handling, analysis, and integration of Daurinoline into wider production lines. Tech staff routinely walk clients through on-site sampling, blending adaptation, and regulatory documentation. Our process chemists can identify which minor adjustments—solvent system tweaks, agitation rates, drying times—reduce in-lab troubleshooting and keep batch records clean. This is the difference that matters for pharmaceutical research and specialty chemical workflows: advice comes straight from the hands running the actual plant equipment.

    On multiple projects, real-time video support and guided start-up troubleshooting sidestep delays. End users receive reports not just on assay and impurity but also practical notes—how the product handled in recent climate cycles, any visible shift in particle size distribution, or case studies where a particular lot cut down on formulation run times. These field notes matter more than spec numbers alone; they offer a proven base for process engineers and analysts blending Daurinoline into complex pathways.

    Toward Better Stewardship—Both for Quality and Safety

    Our responsibility doesn’t stop at the facility gate. Raw material traceability, anti-adulteration protocols, and hands-on batch oversight build confidence both for our own staff and the technicians receiving each shipment. Over the years, we worked with on-site compliance officers, adapting documentation and reporting to real regulatory shifts, not just box-ticking. Before leaving our plant, every lot is checked not only for purity and target composition, but also for absence of flagged contaminants and allergens that cause downstream regulatory headaches.

    Feedback from formulation labs points to a real drop in repeated out-of-spec issues since adopting Daurinoline DA-405. Records back up these claims: fewer batch recalls, more straightforward regulatory submissions, and cleaner audit lines. By focusing on full process transparency, we enable reduced hold times at receiving, easier release in quality-controlled facilities, and smoother compliance checks in both pharma and specialty chemical operations. That’s the peace of mind that only comes when factory, batch log, and field user all work from the same script.

    Looking Toward the Future: Reliable Chemistry, Backed by Experience

    Years on the line have shown that repeatable results in chemistry come from hard-earned lessons—not the broadest marketing campaigns. Daurinoline represents a compound built not just for shelf longevity, but for real, actionable reliability at the hands-on user level. We tune each detail—assay, residuals, moisture, and particle profile—around what real practitioners need, whether working in development labs, contract manufacturing sites, or regulated research settings. Feedback cycles between our plant managers, synthesis staff, and downstream users keep our product relevant in every new run.

    The market may continue to push for cheaper, generic, and indistinct options, but in our view, the people making, scaling, and analyzing chemistry every day deserve accuracy, openness, and results built from working experience. Every batch of Daurinoline we make relies not on shortcuts or vendor mystery, but on the stories and demands of end users—bench chemists, formulation teams, and dedicated process engineers. We believe this approach makes all the difference.