|
HS Code |
742824 |
| Chemical Name | D-Panthenol |
| Other Names | Provitamin B5 |
| Cas Number | 81-13-0 |
| Molecular Formula | C9H19NO4 |
| Molecular Weight | 205.25 g/mol |
| Appearance | Colorless, viscous liquid |
| Solubility | Soluble in water and alcohol |
| Odor | Odorless |
| Melting Point | 64-68°C (crystalline) |
| Boiling Point | 118°C at 1 mmHg |
| Ph Range | 5.0 - 7.5 (5% solution in water) |
| Optical Activity | [α]D20 +29° to +32° (c=2 in water) |
| Stability | Stable under normal storage conditions |
| Function | Moisturizer and humectant in cosmetics |
| Storage Conditions | Keep tightly closed in a cool, dry place |
As an accredited D - Panthenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | D-Panthenol is packaged in a 1 kg airtight, opaque plastic bottle with a tamper-evident seal and clear labeling. |
| Shipping | D-Panthenol is typically shipped in tightly sealed, airtight containers such as HDPE drums, aluminum bottles, or plastic pails to protect it from moisture and light. It should be handled with care, stored in a cool, dry place, and transported according to chemical safety regulations to ensure product integrity and safety. |
| Storage | D-Panthenol should be stored in a tightly sealed container, protected from light and moisture, at a temperature between 15°C and 25°C (59°F and 77°F). Keep it in a cool, dry, and well-ventilated area, away from incompatible substances. Avoid excessive heat and direct sunlight to maintain its stability and prevent degradation. |
| Purity 99%: D - Panthenol Purity 99% is used in topical skin creams, where it enhances skin hydration and accelerates barrier repair.Viscosity 1000 cP: D - Panthenol Viscosity 1000 cP is used in hair conditioners, where it improves spreadability and increases hair shaft moisture retention.Molecular Weight 205.25 g/mol: D - Panthenol Molecular Weight 205.25 g/mol is used in pharmaceutical ointments, where it facilitates efficient dermal absorption and cellular uptake.Stability Temperature 60°C: D - Panthenol Stability Temperature 60°C is used in hot-fill cosmetic emulsions, where it maintains bioactivity and prevents degradation during manufacturing.pH Stability Range 4-7: D - Panthenol pH Stability Range 4-7 is used in facial serums, where it ensures product efficacy and compatibility with sensitive skin.Water Solubility >70 g/L: D - Panthenol Water Solubility >70 g/L is used in aqueous leave-in sprays, where it provides even distribution and rapid absorption. |
Competitive D - Panthenol prices that fit your budget—flexible terms and customized quotes for every order.
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In our manufacturing plant, every batch of D-Panthenol tells a story of consistency, clarity, and decades of technical progress. For colleagues in the cosmetics and pharmaceutical industries, D-Panthenol signals more than an ingredient—it promises reliable performance and proven results. We have worked alongside chemists and process engineers long enough to understand the daily pressures behind every formulation. People look for fewer headaches, less formulation drift, and straightforward supplier support. That starts with how the product leaves our blending tanks: every drum and pail meets a registration certificate. We maintain a 98.0–102.0% assay range for Panthenol content, measured by validated methods and backed by full COA data. Impurities remain well below the pharmacopoeial limits, and you won't find any cheap fillers or masking agents. All of this comes from a production line engineered to minimize batch-to-batch variation and maximize yield.
D-Panthenol, sometimes called Provitamin B5, stands out for its contribution to skin and hair wellness. We have seen how its molecular structure offers unmatched humectancy, drawing in and binding moisture not only on the skin surface but also within hair cuticles. Some new entrants have pushed for lower-cost panthenol blends or lower-grade imports, but trace analysis tells a different story: impurities, aldehyde by-products, and unwanted color develop in those variants over time. Our product stays clear, colorless, and non-crystallizing across a range of storage temperatures. Customer feedback often singles out this clarity—no off-odors, no yellow tinge, no sticky residues—just a pure, easily handled viscous liquid. Each drum carries a full batch history and a guarantee on D-isomer content, because we recognize that optical purity determines real-world benefit and marketing claims.
Clients formulate D-Panthenol into shampoos, facial creams, after-sun gels, wound-care ointments, and more. They value the way D-Panthenol resists hydrolysis and oxidation when they stress-test their products. In our R&D trials, it remains stable even after repeated exposure to light and temperature cycles that mimic retail shelf conditions. We invest in this quality, routinely screening incoming intermediates and finished stock for oxidation products and microbial contamination far beyond routine minimums. Our traceability policy avoids grey-market risks, and we maintain full batch samples for post-shipment investigations or recalls. This comes not from regulatory pressure, but from watching clients face avoidable formulation breakdowns from inferior supply chains.
The market sometimes offers racemic Panthenol (DL-form), or calcium pantothenate as a replacement. Years of practical compounding show why these substitutions disappoint. Only the D-form demonstrates complete bioconversion to pantothenic acid—a crucial factor for formulators aiming to meet measurable claims on skin barrier reinforcement or hair strength. Our customers see the difference in clinical trial outcomes and consumer feedback: poor substitutes often contribute to residue buildup, less effective hydration, or changes in viscosity and feel. None of this is academic; poorly chosen panthenol sources push up QA and regulatory costs, trigger more product recalls, and undermine brand integrity. We know this because fielding calls for technical support dominates our application engineering team’s day whenever customers switch to rival, off-brand panthenol.
Before a single drum ships, it completes a full spectrum of tests—HPLC analysis, optical rotation, aeration stability, pH, microbial count, and heavy metals. Most competitors, especially smaller traders, skip testing for certain low-level contaminants that can have outsize impacts in finished personal care formulas. Each batch undergoes stress testing to simulate various excipient blends, so formulators avoid surprises late in their product development pipeline. We built these practices over forty years and count more than 500 production runs without an out-of-spec return. Our investment is rooted not only in meeting written standards, but in keeping every factory customer running smoothly.
Not all manufacturing lines for D-Panthenol deliver the same result. Our line runs dedicated reactors, set for 99.5+% isomeric conversion and advanced purification. Technicians cross-check moisture content and viscosity every eight hours during running and again post-packaging. Too much residual water or inconsistent viscosity can affect pump systems and filling operations at the customer’s site—something we learned after auditing hundreds of line stoppages in finished goods factories that traced back to poor-quality ingredients. Our clients count on receiving the same product profile every shipment, because reproducibility anchors their own productivity and reputation.
We provide formulation support based on the seasons and climate: Panthenol’s behavior shifts slightly in high-humidity or low-temperature conditions. Decades of shipping experience led us to adjust our packaging design to prevent crystallization during international sea freight or long-haul land transport. Each container comes with real-time temperature indicators and tamper-proof seals. Storage guides educate facility managers about preventing light and air ingress—details that seem minor, but which stop costly exclusion-related degradation. Even our labeling is chosen for solvent resistance, so information does not fade or wash away under bulk transfer operations. Over time, such improvements have driven customer complaint rates near zero, because we take care before the product leaves our premises.
Anyone who has worked with hair conditioning or shampoo formulas knows how ingredient interactions get complicated. Our D-Panthenol excels in both clear and opaque systems—unlike some lower-grade materials that introduce opalescence or phase separation. We constantly run field trials with major partners to test compatibility with surfactants, silicones, and protein blends. Feedback points to strong wet and dry combability improvements with our grade, often attributed to high optical purity and low particulate count. We have helped customers solve foam stability and viscosity drift in high-active systems by sharing process tweaks backed by our long manufacturing track record.
The consumer market is crowded with “hydration boosters,” yet formulators rely on evidence-backed claims. D-Panthenol stands out for supporting faster wound healing and stronger skin barrier recovery. Multiple studies identify the D-specific isomer as the active principle behind improved hydration and reduced transepidermal water loss. We align our specs with published clinical literature to make regulatory submissions easier for finished product makers. Where others chase volume sales with low-cost blends, we support customers presenting their test results to regulators and retailers, providing traceable documentation out of our in-house lab. Transparent collaboration with our users keeps formulations both novel and compliant.
Lesser-known benefits from a consistent, high-purity D-Panthenol go beyond product performance. Operators on the filling line report less clogging and fewer cleanups from sticky residues. Quality control teams find faster throughput because viscosity readings and pH check out on the first run—an everyday reality in a busy manufacturing setup. Workers gain from reduced exposure incidents, owing to fewer off-odors and safer material handling. We arrive at these points by walking the shop floor with our partners, learning where operational pain points start, and aligning our product spec to reduce issues at the source.
Sustainability means less if it stops at marketing slogans. Our D-Panthenol line is fed by a closed water system and high-yield reactors that cut down raw material use by over twenty percent compared to traditional processes. Solvents and effluents undergo advanced treatment, not only to meet but to defeat emission regulations. Every year, we submit our plant to third-party audits that cover environmental records, worker safety, and traceability. Clients in European markets, where the regulatory regime demands eco-responsibility, ask for proof of green chemistry practices. We supply this evidence as a matter of policy, not posturing, because we have built the production backbone for a long-haul relationship with our supply partners.
Production chemists and industrial buyers stick with our D-Panthenol for several practical reasons. Injection molding lines that use our batch experience lower rejection rates. Cream and lotion lines maintain batch integrity longer, especially through hot-cold packaging cycles. Lab managers report higher pass rates during microbiological challenge testing, due to cleaner input material. No surprise: a decade of regular purchasing partners cites the steadiness of our output as their reason for rarely adjusting their SOPs. Regulatory officers request supporting technical files, shelf-life data, and allergen information. We provide these instantly, because each run is tightly catalogued from raw input through QC release.
Every year brings new expectations. Trends mean nothing without sound supply chains and consistent chemical quality. Our investment in process automation, in-line NIR checks, and cloud-based production monitoring reflects hard-won experience: digital controls reduce manual error, spot input drift, and let us share up-to-the-minute data with customer QA teams. We set up regular calls with large industrial partners to fine-tune every incoming lot, especially as local regulatory pressures shift. Feedback drives formulation tweaks—changing antioxidant levels, fine-tuning solubility curves for emulsion systems, or boosting clarity for clear gel applications. Instead of seeing custom specs as a burden, we view each request as an opportunity to anchor our products deeper into the client’s workflow.
Panthenol remains favored where brands push “active” or “clean” labels. We see our product move into natural and vegan-certified lines, since our synthesis avoids animal-derived intermediates. Each batch supports downstream “free from” claims—no allergens, no genetically modified inputs, no parabens, no formaldehyde donors. Cosmetic formulators look for gentle yet effective materials for sensitive skin lines, therapeutic creams, and pediatric care. Many of the world’s most recognized consumer brands vet our production line yearly, checking for residuals, supply chain transparency, and ethical controls. Rapid response to these evolving standards keeps their product launches on schedule and within scope.
Constraints on vitamin input prices, transport disruptions, or regulatory shifts create constant challenge. Raw material volatility sometimes pressures margins to the limit, yet our focus remains on supplying the same quality, not cutting corners. We have managed multiple years of raw input turbulence thanks to prebuilt stockpiles, supplier diversification, and routine scenario planning with our logistics partners. Clients share their forecasts six, twelve, or even twenty-four months ahead to help us adjust output levels and build to expectation. Unlike some short-term traders, we never downgrade product quality to meet a price demand. Instead, long-term supply agreements, risk-sharing contracts, and shared inventory hubs smooth these challenges for everyone involved.
While personal care consumes much of the market, D-Panthenol advances in topical pharmaceuticals, eye drops, and veterinary treatments. Quality bar rises for these segments: every impurity, trace heavy metal, and microbiological count must clear more stringent hurdles. Our pharmaceutical-grade D-Panthenol batches meet multiple monograph requirements, opening doors for our clients in regulated OTC and prescription products. We respond to customer requests for additional viral, bacterial, and endotoxin screening prior to each release—a process that has decreased registration rejections across Asia, Europe, and North America.
From the vantage point of a production floor, the true cost of D-Panthenol cannot be pinned down simply to per-kilo pricing. Technical support, traceability, lot-for-lot consistency, and deep field knowledge matter as much as measurable purity. We see daily how these factors anchor customer trust, help prevent line stoppages, and propel our partners through regulatory compliance with fewer headaches. Any time a customer faces an unexpected challenge in formulation, they know they can call direct to an expert who knows exactly what has (and has not) gone into each lot. That openness, honed by decades of experience, is how top manufacturers support their partners with more than chemistry. D-Panthenol remains an ingredient with real backbone in both formulation and supply chain logic—and our team stands behind every batch, every day, because we know that’s how a manufacturer earns its stripes.