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Conjugated Linoleic Acid

    • Product Name Conjugated Linoleic Acid
    • Alias CLA
    • Einecs 242-562-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    420002

    Product Name Conjugated Linoleic Acid
    Abbreviation CLA
    Chemical Structure Isomer of linoleic acid
    Source Found in meat and dairy products from ruminants
    Form Available as capsule, softgel, powder, and liquid
    Primary Uses Dietary supplement for weight management
    Mechanism Of Action Affects body composition by modulating fat metabolism
    Recommended Dosage Typically 1,000–3,000 mg per day
    Solubility Fat-soluble
    Typical Serving Size 1-2 softgels (1,000 mg each)
    Taste Neutral to slightly oily
    Common Side Effects Digestive upset, diarrhea, nausea
    Color Pale yellow to golden liquid in pure form
    Storage Conditions Store in a cool, dry place away from sunlight
    Dietary Suitability Suitable for most diets; check for animal source if vegan/vegetarian

    As an accredited Conjugated Linoleic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Conjugated Linoleic Acid is packaged in a white plastic bottle containing 100 softgel capsules, each clearly labeled with supplement facts.
    Shipping Conjugated Linoleic Acid (CLA) is shipped in tightly sealed, food-grade containers or drums to protect against moisture, light, and air exposure. It should be stored in cool, dry conditions during transit. Proper labeling and documentation are required, and the product is typically shipped as a non-hazardous material.
    Storage Conjugated Linoleic Acid (CLA) should be stored in a tightly sealed container, protected from light and moisture, and kept at a cool temperature—ideally below 25°C (77°F). Store it in a dry, well-ventilated area away from incompatible substances such as strong oxidizers. Refrigeration may help extend shelf life, but avoid freezing. Always follow manufacturer or supplier guidelines for optimal storage conditions.
    Application of Conjugated Linoleic Acid

    Purity 98%: Conjugated Linoleic Acid with 98% purity is used in dietary supplement formulations, where it enhances body fat reduction and supports lean muscle mass maintenance.

    Isomeric Composition 80% c9,t11: Conjugated Linoleic Acid with 80% c9,t11 isomeric composition is used in functional foods, where it improves antioxidant capacity and modulates lipid metabolism.

    Molecular Weight 280.45 g/mol: Conjugated Linoleic Acid with a molecular weight of 280.45 g/mol is used in nutraceutical manufacturing, where it ensures controlled release and optimal bioavailability in human metabolism.

    Stability Temperature up to 60°C: Conjugated Linoleic Acid with a stability temperature up to 60°C is used in processed food production, where it maintains structural integrity and prevents degradation during thermal processing.

    Particle Size <50 µm: Conjugated Linoleic Acid with a particle size of less than 50 micrometers is used in microencapsulation techniques, where it achieves improved dispersibility and longer shelf life.

    Residual Solvent <0.1%: Conjugated Linoleic Acid with residual solvent content below 0.1% is used in pharmaceutical applications, where it guarantees high purity suitable for human consumption and minimizes toxicity risks.

    Peroxide Value <1 meq/kg: Conjugated Linoleic Acid with a peroxide value below 1 meq/kg is used in cosmetic emulsions, where it ensures product stability and prevents oxidative rancidity.

    Odorless Grade: Conjugated Linoleic Acid odorless grade is used in flavor-sensitive food products, where it enables incorporation without altering organoleptic properties.

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    Certification & Compliance
    More Introduction

    Conjugated Linoleic Acid: Supporting Progress in Nutrition and Health

    Discovery, Production, and Innovation

    Working on the frontline of chemical creation, we have observed how conjugated linoleic acid (often abbreviated as CLA) has drawn the focus of both nutritional science and industry markets. The journey with CLA goes back to the late 1970s, when researchers identified it in the process of cooking beef. We started producing CLA for commercial and research use after recognizing the significance of its natural presence in ruminant-derived foods and the challenges of extracting enough from animal fat alone. The approach involves safe alkaline isomerization of linoleic acid, typically sourced from safflower oil. By carefully controlling process parameters such as temperature and catalyst composition, we produce high-purity, food-grade CLA in both free fatty acid (FFA) and triglyceride (TG) forms.

    Not every batch leaves our tanks identical; specifications reflect final destination and customer application. In food supplementation, we provide CLA with a minimum of 80% conjugated linoleic acid isomers, usually split between cis-9, trans-11 and trans-10, cis-12, the two isomers most researched for their biological effects. We keep the content of trans-10, cis-12 above 40%, since this isomer has gained attention in fat metabolism studies. Moisture, peroxide values, and heavy metal content all stand well below international thresholds set by trusted authorities. We authenticate product identity by gas chromatography and, for certain applications, further process to remove minor fatty acids and oxidized components.

    Real-World Applications: What Drives Markets to CLA

    Our experience shows strong growth in three main sectors: functional foods, dietary supplements, and animal nutrition. Food formulation partners rely on us for CLA that integrates easily into softgel capsules, powders, and beverages. Attention to oxidative stability ensures that dietary supplement products maintain their potency over years, not just months. Fat-rich foods and infant formulas also benefit from our addition of CLA triglycerides, offering closer resemblance to dairy lipids found in breast milk.

    Ruminant feed manufacturers aim for increased milk fat quality and altered fatty acid composition in animal products. This application grows every year, especially in dairy herds, where the modification of cow feed can enrich CLA content in milk and cheese, responding to consumer desire for natural CLA-enriched foods. To this sector, we deliver feed-grade CLA that meets both purity and palatability requirements. Because ruminant digestion presents unique challenges, we regularly work with animal nutritionists to optimize granule and powder formulations for consistent delivery.

    Sports nutrition and weight management industries also keep CLA demand strong. As a direct ingredient in softgel capsules, the purity and precise ratio of main isomers takes priority. Our technical team often collaborates with formulators during scale-up, ensuring shelf stability and sensory qualities fit stringent supplement standards.

    Standing Apart: How Our CLA Differs from Conventional Lipids and Market Alternatives

    Our production plant runs round-the-clock to meet the need for CLA at high concentrations and with stable, predictable profiles of active isomers. Linoleic acid, the starting material, occurs abundantly in vegetable oils. The natural form found in plant oils contains no conjoined double bonds; instead, we apply controlled isomerization to generate the characteristic conjugated structure. This gives CLA its characteristic biological activity, entirely distinct from non-conjugated linoleic acid.

    Pure plant oils, even premium grades, cannot provide the specific isomers or concentrations of CLA that research has found beneficial. Real conjugated linoleic acid, as manufactured in our facilities, features twin double bonds spaced by only one carbon. This detail sets it apart from standard polyunsaturated fatty acids, both in chemistry and biological impact, and makes direct extraction from plant oils impossible at meaningful quantities.

    Fish oils and omega-3 supplements frequently arrive at warehouses worldwide, supplying EPA and DHA. Yet, their activity follows different metabolic pathways and health outcomes. CLA occupies its own chemical “niche,” modulating body composition, lipid metabolism, and immune response in ways that omega-3s do not. Some products on the market blend plant seed oils under misleading labels or provide “CLA-complexes” with only trace amounts of authentic isomers. We maintain strict traceability, using only high-CLA materials confirmed by chromatographic analysis.

    Meeting Quality, Safety, and Environmental Goals

    We oversee every stage, from acquisition of linoleic acid-rich oils to finished packaging. Our teams run regular safety audits and contamination checks, ensuring that all finished product meets food safety certification for human and animal use. Batch records extend back years, with analytical reports attached at every shipment. Regulatory bodies in North America, Europe, and Asia recognize the specifications we maintain, and our products comply with the additive and supplement guidelines in those regions.

    A challenge continues to loom over industrial production: minimizing residual solvents and byproducts in the final oil. We target less than 0.5% by mass of non-CLA fatty acids and use vacuum distillation to eliminate unwanted impurities. By recycling process solutions and optimizing reactor cycles, we have been able to lower not only chemical waste but also energy usage. Solar panels and cogeneration units power much of our plant floor, cutting down fossil fuel reliance and lowering the environmental cost per kilogram of API delivered.

    Odor and sensory properties matter. Many manufacturers ignore these subtleties, but end users detect even faint byproducts. By investing in deodorization and filtering units, we regularly achieve cleaner-tasting CLA, free from rancid or fishy notes, ready for use in flavored food or beverage applications. Our partners routinely comment on the difference.

    Transparency, Research, and Future Potential

    We support scientific research, providing material and technical advice for peer-reviewed studies. Over the past decade, research with our CLA has explored effects on body composition, lipid metabolism, and immunomodulation in humans and livestock. Meta-analyses of clinical trials indicate a reduction in body fat mass among adults using CLA supplements—at doses between 2 to 6 grams daily. Early findings in children remain limited, so we err on the side of caution in marketing to the youngest consumers.

    In animal research, CLA has shown potential for raising milk output in dairy cattle, suppressing methane emissions in ruminants, and boosting lean muscle accretion in broilers and swine. These studies have shaped the application guidelines we provide to animal nutrition customers. Knowing that high dosing can disrupt rumen fermentation or cause off-flavors, we advise gradual inclusion and periodic analysis of milk or meat fatty acid profile.

    We maintain ongoing collaborations with universities, supporting independent validation of process improvements and downstream benefits. Through this feedback loop, our process engineers continually tweak isomer ratios and purification steps, keeping us at the forefront of manufacturing standards. Lessons learned from these studies circle back into upgraded specifications, better shelf life, and improved customer guidance.

    Solutions to Ongoing Industry Challenges

    Scaling up from lab-scale to industrial production rarely goes according to textbook plans. Insufficient mixing or reaction temperature lapse for even half an hour will skew the isomer balance, resulting in out-of-spec product. By automating controls and integrating real-time chromatography, we keep process drift in check.

    Oxidative stability creates another challenge. Conjugated double bonds react more quickly with oxygen than other fatty acids, generating off odors, color darkening, and potency loss. Instead of relying solely on antioxidants, we designed our tank farm and pipelines to carry an inert nitrogen blanket. Combined with advanced drum-sealing and vacuum filling, this strategy holds peroxide values below 4 meq/kg at the time of shipment, and often down to 1 meq/kg or lower.

    Batches destined for livestock often require microencapsulation to survive rumen breakdown. This step adds cost and complexity, but it pays off in biological availability and effective delivery, especially when used in herd-scale operations. We’ve developed processes to encapsulate CLA with natural proteins and lipids, offering better dispersion in pelletized feeds and avoiding unpalatable odors in the finished ration.

    We also field regular questions about the impact of genetically modified (GM) starting material. Though most global regulatory agencies accept GM safflower oil for industrial use, we still maintain segregated process lines for certified non-GMO product, providing chain-of-custody documentation. Though some competitors recycle all batches through the same process bays, we separate non-GMO from conventional from the first drum to the last.

    CLA for a Changing Consumer Landscape

    Consumers today want to know the story behind their supplements and food components. Our customers increasingly request transparency not only about content but also about production steps, sustainable sourcing, and environmental impact. We respond by keeping documentation open, running environmental reporting, and supporting independent third-party audits every year.

    We commit to ongoing improvement—not out of regulatory pressure, but because we live alongside the markets we serve. Trace heavy metals, pesticide residues, and solvent limits keep creeping downward in regulatory standards, so our analytics team invests in ever-sensitiver mass spectrometers and GC-MS systems. This approach also heads off any surprises with global shipments, reducing customs delays and frustration for everyone downstream.

    The future market for CLA will likely expand into personalized nutrition and specialty animal products. Already, we have fielded requests for microbially produced CLA, traced all the way back to bioreactor, and allergen-free variants for highly sensitive applications. Our technical development team actively experiments with enzymatic isomerization and bio-catalytic options in place of classic chemical synthesis. Newer methods mean less waste, fewer harsh byproducts, and tighter control over isomer ratios. We invest heavily in these efforts because each improvement stabilizes our supply, lowers environmental impact, and opens up fresh markets that traditional manufacturing cannot reach.

    Trust Built on Expertise and Customer Partnership

    Being a manufacturer, not a trader, gives us direct responsibility for product performance and success of our partners. Each phase, from oil sourcing to tanker cleaning and drum palletization, happens with the end user in mind. If an unforeseen specification challenge arises, the technical and quality team work hand-in-hand with the customer, providing both corrective measures and, when needed, reformulation advice to help companies still meet production targets.

    In our day-to-day experience, demands often evolve, new questions arise, and batch requirements shift quickly in response to changing regulations or new clinical recommendations. We welcome this partnership approach, seeing it not as a burden but as a source of knowledge and ingenuity. Unlike third parties, we control process changes directly, tracking every tweak in manufacturing records and updating customers as needed.

    The people behind sports supplement brands, food manufacturers, research groups, and animal nutrition companies trust our expertise because they have seen consistent outcomes over time. They have watched as changes in material specification, encapsulation, or delivery format fit new scientific recommendations or regulatory shifts. We stay at the table long after the first sale, adjusting parameters, supporting shelf life studies, and finding better ways forward.

    Pushing Forward with CLA Research and Application

    As demand for natural, functional ingredients rises and research continues to reveal the potential of bioactive fatty acids, conjugated linoleic acid holds a special place in our production lineup. We commit to refining specifications, lowering environmental impact, and supporting both established and emerging markets. With ongoing investment in process optimization, real-world problem-solving, and transparent partnership, we aim to set a benchmark for how specialized ingredients should be manufactured and supplied.

    CLA may not solve every challenge at the intersection of nutrition, health, and sustainability, but it represents what is possible when manufacturers and end users build lasting trust. By listening, learning, and driving research-based improvements together, the whole industry stands to gain. This approach keeps us grounded, committed, and always in pursuit of what genuine scientific evidence and practical application can achieve.