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Citrusinine I

    • Product Name Citrusinine I
    • Alias Citrusinine-I
    • Einecs 94332-25-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    192556

    name Citrusinine I
    chemical_formula C22H27NO2
    appearance Yellow solid
    solubility Insoluble in water, soluble in organic solvents
    source Citrus plants
    class Alkaloid
    CAS_number 146992-16-9
    IUPAC_name 7-(3-methylbut-2-enyl)-1,2,3,4,6,7,8,9-octahydro-2,8-methano-8H-pyrido[1,2-a]azocine-10,11-dione
    bioactivity Anticancer, antimicrobial
    structure_type Polycyclic alkaloid
    isolation_year 1992
    optical_activity Chiral, optically active
    storage_conditions Store in cool, dry place

    As an accredited Citrusinine I factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Citrusinine I is packaged in a 500 mg amber glass vial with a tamper-evident cap and clear labeling for identification.
    Shipping Citrusinine I is shipped in sealed, chemically resistant containers to prevent contamination or degradation. Packages comply with international regulations for chemical transport, including appropriate labeling and documentation. During transit, shipments are protected from moisture, heat, and direct sunlight. Handling instructions and safety data sheets accompany each order to ensure safe delivery and use.
    Storage Citrusinine I should be stored in a tightly sealed container, protected from light, moisture, and air. Keep it in a cool, dry place, ideally at 2–8°C (refrigerator temperature). Ensure the storage area is well-ventilated and away from incompatible substances such as strong oxidizing agents. Properly label the container and restrict access to qualified personnel only.
    Application of Citrusinine I

    Applications of Citrusinine I in Industrial Manufacturing

    Citrusinine I is a highly specialized alkaloid extracted primarily from the citrus genus and has generated significant attention among formulators and technical engineers for its unique bio-functional properties. Our direct manufacturing and quality assurance processes ensure a supply chain solution adaptable to diverse industrial environments. Below, we outline four established downstream segments where Citrusinine I demonstrates proven, differentiated utility in mass-scale applications.

    1. Pharmaceutical Intermediate for Antimicrobial Drug Synthesis

    In pharmaceutical active ingredient processing, Citrusinine I functions as a distinct heterocyclic intermediate for specific antimicrobial and antifungal drug classes. Fine chemical engineers utilize its alkaloid backbone during multi-step organic synthesis to introduce rare bioactive moieties, driving the development of next-generation agents targeting drug-resistant strains. Production managers consider this raw material valuable due to its stability in harsh reaction conditions, enabling efficient transformation and yield management during large-scale manufacturing of proprietary molecules.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) monograph references for intermediates
    • US FDA 21 CFR Part 211 for pharmaceutical quality systems
    • Chinese Pharmacopoeia, latest edition, raw intermediate requirements

    Typical usage ratio

    • Standard input at 1.0–6.0% w/w relative to core substrate, adjusted based on desired functional group conversion efficiency and downstream antimicrobial analog structure

    Downstream process integration

    • Stagewise introduction during mid-phase chemical synthesis, serving as an N-heterocyclic building block within reaction vessels equipped for solvent management and temperature control

    Final product types

    • Semi-synthetic antibiotics tablets, capsules, and injectable formulations
    • Topical antifungal creams and ointments
    • Specialty molecular entity APIs for licensing and out-licensing

    2. Biopesticide Formulations for Post-Harvest Agricultural Treatment

    Agricultural innovation centers employ Citrusinine I as a botanically-sourced key ingredient for the design of biopesticide solutions, specifically for mitigating fungal contamination during the post-harvest storage and transport phase. Researchers and regulatory-compliant manufacturers appreciate its selectivity and natural origin—addressing both sustainability certification and residue restriction demands. The formulation team typically disperses it in aqueous carrier systems that ensure uniform application and coverage during commercial-scale produce treatments, optimizing shelf life extension strategies and reducing post-harvest losses.

    Industry compliance standards

    • FAO/WHO Codex Alimentarius MCFA maximum residue limits for post-harvest fungicides
    • EU Regulation (EC) No 1107/2009 for plant protection products
    • US EPA FIFRA Biopesticide Registration Guidelines
    • ISO 22000 for food safety management in agrochemical production

    Typical usage ratio

    • Typical application of 0.2–1.2% concentration in final sprayable solution, tailored to specific commodity type and anticipated post-harvest infection pressure

    Downstream process integration

    • Blending of Citrusinine I during the formulation of water-based emulsions or wettable powders at pre-filling stages, followed by homogenization and microfiltration for batch consistency

    Final product types

    • Commercial post-harvest fruit and vegetable sprays
    • Edible crop coatings for export-grade produce
    • Biodegradable grain preservative packets for silos and containers

    3. Cosmetic Active Ingredient for Anti-Dandruff and Scalp Care Lines

    Major personal care brand manufacturers apply Citrusinine I as a novel functional compound targeting the scalp microbiome. R&D groups have incorporated it into rinse-off and leave-on skin treatment ranges where anti-microbial and anti-inflammatory actions are required without synthetic preservative systems. It integrates well during the cooling phase of batch compounding—critical for stability—ensuring no degradation before packaging. Regulatory affairs teams further favor this molecule for its traceable natural derivation and compatibility with clean beauty claims during audits and marketing launches.

    Industry compliance standards

    • EU Cosmetics Regulation EC 1223/2009 on safety assessment
    • US FDA Voluntary Cosmetic Registration Program (VCRP) for ingredient transparency
    • ISO 22716: Cosmetic GMP guidelines
    • Cruelty-Free and COSMOS Natural standards for ingredient sourcing

    Typical usage ratio

    • Active inclusion at 0.15–0.6% in finished formulas, adjusted according to total surfactant or emollient system and required anti-dandruff performance verified by clinical patch panels

    Downstream process integration

    • Metered dosing following the base neutralization stage of emulsion or micellar matrix assembly, prior to performance testing and stability QC sign-off

    Final product types

    • Shampoos and scalp treatment serums
    • Non-steroidal anti-dandruff creams
    • Micellar scalp cleansers for sensitive skin

    4. Functional Ingredient in Nutraceutical Supplement Production

    Health supplement contract producers utilize Citrusinine I for its documented bioactivity within select dietary supplement blends. Ingredient sourcing specialists rely on our GMP-compliant traceability from botanical extraction to industrial crystallization, ensuring batch purity continuity under regulatory scrutiny. Industrial blenders incorporate the ingredient into multi-component powder preparations, using low-temperature blending to protect sensitive bioactive profiles and support label claims related to antioxidant support. Finished lot QC employs quantitative analytics to confirm accurate inclusion prior to encapsulation or tableting.

    Industry compliance standards

    • US FDA 21 CFR Part 111 (Current Good Manufacturing Practices for Dietary Supplements)
    • EFSA (European Food Safety Authority) guidance on novel foods and food supplements
    • China GB 16740-2014 National Food Safety Standard for Dietary Supplements
    • NSF/ANSI 173 – Dietary Supplement Certification

    Typical usage ratio

    • Main inclusion level ranges from 0.05–0.25% by mass per batch, adjusted according to finished capsule dosage, intended biofunctional claim, and regional regulatory restrictions

    Downstream process integration

    • Direct blending into pre-mix stages at controlled humidity, prior to carrier excipient addition and subsequent automated encapsulation or tableting

    Final product types

    • Capsule-based dietary supplements
    • Tablet formulations for daily wellness
    • Effervescent powder blends targeting antioxidant activity
    Free Quote

    Competitive Citrusinine I prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing Citrusinine I: Practical Experience from the Factory Floor

    A Craft Rooted in Precision Chemistry

    Daily life in our manufacturing plant revolves around chemistry you can hold, measure, and trust. Among our portfolio, Citrusinine I stands out due to its reliable performance in many applications that count on purity and consistency. We have carried this compound through every step ourselves, controlling the process from sourcing precursors to the final packaged product. For a chemical like Citrusinine I, attention to every little reaction detail is more than procedure—it guarantees the product delivers on what customers expect in demanding environments.

    What Makes Citrusinine I Unique

    Our specific model of Citrusinine I features thorough crystallization and screening, yielding a material that meets tight purity targets demanded across sectors. Over time on the production line, we saw how trace contaminants or leftover solvent residues throw a wrench in downstream use. Peel away the laboratory labels and sales language, and you realize that consistency in melting point, color, and solubility impacts every batch. Our staff, many with more than a decade’s hands-on experience, monitor every run and keep strict logs on lots and yields. This hands-on approach shortens troubleshooting and helps us identify the little adjustments that keep Citrusinine I meeting spec.

    For the technical users, Citrusinine I often arrives in a crystalline powder form with a specific melting range and a purity that regularly tests above the 98% mark by HPLC. Moisture content sits below the trace limit, so no extra drying steps slow your process. The reason we can reach these numbers isn’t magic. Each filter change, vacuum calibration, and sample pull during synthesis add up to a standard we recognize from the finished drums leaving our dock.

    Meeting Customer Needs Beyond Datasheets

    In the many years producing Citrusinine I, we have seen its role stretch from intermediate uses in pharmaceutical synthesis to segments of specialty dyes and materials science. One customer needs robust performance in organic synthesis with minimum batch-to-batch drift; another pushes for a dust-free pour to simplify loading into reactors. Batch records tell one story, but talking with technical staff at the point of use reveals the details that shape our ongoing product improvements.

    The most common feedback centers on two things: clean solubility profiles in a range of standard solvents, and absence of trace metals that could poison catalysts. Our refinement steps strip out metals down to the low ppm levels, and our R&D team often consults with end-users to tweak washing steps if requirements change. We view these ongoing dialogs as essential, not optional, when you want customers to trust your powder over the long haul.

    Handling and Workability

    Laboratory chemists and industrial engineers both comment on the way Citrusinine I handles on the bench or in automated filling systems. We have poured thousands of kilos, so we know small batch clumping or unpredictable flow leads to longer cleanouts and inconsistent dosing. Factory staff routinely check pack density and monitor dust levels inside hoppers. Tweaks like extra sieving or a careful drying step often come straight from the shop floor, where real users notice these little improvements before anyone in the office writes a report.

    We steer clear of ambiguous promises and stick to what workers in coats and coveralls tell us: smooth pouring, with minimal static or dust kick-up. Environmental monitoring makes sure workers and product both stay safe, while a robust supply of desiccant inside every pack keeps moisture from creeping in, even during summer shipping.

    Comparison to Other Anthraquinone Derivatives

    Buyers often ask why our Citrusinine I stands apart from other anthraquinone-based products or similar molecular structures. Many chemicals in this family share backbone features, but what sets ours apart lies in both raw material quality and controlled process tweaks. Our choice of starting anthraquinone grades means fewer color bodies or isomeric by-products reach the final lot. We worked side-by-side with quality assurance teams during scale-up to keep this stringently enforced.

    Some suppliers sell mixed fractions under generic names, with wide melting ranges and an unpredictable impurity profile. These may work in broad applications, but specialty users targeting sensitive reactions or high-precision outcomes need reproducibility. That’s where we deliver: batch after batch, with documented controls from synthesis to packaging. The difference is felt when a customer doesn’t need to recalibrate every time our shipment arrives. Over time, this saves cost and time—value our partners appreciate far beyond the sticker price.

    End-Use Experience Speaks the Truth

    Many manufacturers promote narrow technical comparisons, showing charts and numbers. On the production floor, performance comes down to what chemists, operators, and automation lines see every day. Whether the compound dissolves right where expected, whether color or odor interfere with sensitive end-products, whether every pail matches the last in appearance and label information—these are the factors that shape loyalty.

    Through direct communication channels—hotline, email, in-person site visits—we hear about challenges customers face working with other suppliers. Contamination worries, inconsistent grain size, or short shelf life cause headaches that never make it into published spec sheets. We actively invite this feedback, so each lot of Citrusinine I reflects ongoing improvement based on field realities rather than marketing theories.

    Quality Control: Reality at Every Step

    Conversations about chemical quality tend to drift abstract. At our plant, quality means specific protocols. Sample every batch, run side-by-side comparison to reference lots, and analyze impurity levels by gas chromatography, HPLC, and ICP-OES for trace elements. Only after all boxes are checked does material move ahead to the final packing floor. Personnel are empowered to raise an alert over minor variations—our record shows that giving every team member authority over quality stops problems before they scale up.

    Finished Citrusinine I lots receive batch-specific certificates, including retention samples archived for years. This gives peace of mind to customers tracing back performance changes or responding to regulatory inquiries. We don’t “release” any material until stability and purity data check out, and site audits from third parties offer external confirmation of our routines. For audited industries—such as pharmaceuticals and regulated materials—we gladly cooperate with on-site inspection teams and pride ourselves on answering even challenging technical questions face-to-face.

    Supplying a Reliable Chain

    Instability in raw material supply chains throws off everything from pricing to batch timing. Unlike traders who source opportunistically, we enter long-term partnerships with our feedstock vendors, sometimes making site visits to check their production and handling firsthand. Years of relationship-building anchor us against market spikes or unexpected shortages, so we rarely need to inform customers about product interruptions.

    Batch timelines and large-scale demand swings mean we must keep buffer inventory ready. We carry safety stocks and run test syntheses well before forecast upticks. Each quarter’s plan incorporates historical sales data, customer pipeline projects, and raw material purchasing commitments. These habits come straight from the manufacturing world, not a spreadsheet in an office tower.

    Supporting Material Innovation Down the Line

    Researchers and manufacturing partners often explore new uses for molecules like Citrusinine I, whether as a template scaffold in drug discovery or as a chromophore in advanced dye systems. As a factory, we see firsthand that these product development cycles rely not just on chemistry, but also on timely technical support. Real questions come up—how does Citrusinine I respond in scaled-up reactions, what levels of residual acidity appear, or will its physical properties remain stable in a composite material after six months? We answer by running small pilot batches, sending free-of-cost physical samples for trial experiments, and inviting project teams into our site to view runs up close. These experiences inform both our product’s evolution and the support we give on the journey from concept to commercial scale.

    This tight feedback loop—factory to laboratory to customer—keeps us nimble. Adjustments to synthesis conditions, packaging, or even labeling, respond directly to new demands as they arise. We have changed filter formats, updated drying regimens, and even offered new drum sizes at the request of real users. None of this would happen if we treated Citrusinine I as just another catalog entry.

    Sustainability and Waste Reduction at Source

    Large-scale manufacturing today faces real pressure to limit energy, reduce solvent consumption, and address safe waste handling. With Citrusinine I, we prioritized green process redesigns that shave hours and liters from every run. Closed-loop filtration systems recover and reuse solvents, reducing environmental footprint and minimizing operator exposure. Our continuous process improvements mean less batch variability, while responsible disposal and recycling of process residues prevent hazardous buildup.

    Our customers increasingly ask about traceability and eco-impact. We provide full transparency—auditable records of every raw material lot, waste treatment, and emission level tied to each run of Citrusinine I. On site, safety walks and environmental audits reinforce a factory culture that values accountability from the top down. Importantly, these improvements benefit both users downstream and the staff making the compound day-in, day-out.

    Transparency and Traceability for a Trusted Product

    Trust grows from openness with both partners and official bodies. Auditable records detail every kilogram of Citrusinine I from raw material to finished good. We maintain batch sample archives, so users tracing any technical hiccup can access exact production conditions. Each order includes full batch analytics, and trained technical staff remain available to discuss any special analytical needs.

    We have handled customer requests for full site audits or regulatory documentation multiple times throughout the year. Our plant managers and quality supervisors take these as opportunities, not burdens—chance to engage with stakeholders, demonstrate best practices, and learn from critical eyes outside our own team. In the rare case questions appear about possible impurities, we initiate a rapid track-trace analysis and communicate findings clearly and quickly.

    Packaging That Protects the Product

    Packaging isn’t simply a logistics matter. Incorrect or ill-chosen packaging constrains usability and risks contamination. We worked through years of feedback to optimize drums, liners, and bagging processes, settling on triple-sealed pails for routine quantities and custom vessel options for large-scale buyers. Moisture scavengers and oxygen absorbers ship with every container to guard sensitive contents over long distribution routes.

    Operators oversee every handling step: from controlled filling in low-humidity rooms to weight-checked sealing and robust pallet strapping. The goal is always to deliver Citrusinine I in exactly the state it left our packing line. Each outgoing shipment gets a complete visual inspection and labeling check by trained staff, reducing mix-ups that too often occur when more hands move product between sites.

    Learning from Direct Engagement

    Real-world feedback from users trumps laboratory conjecture. Some industrial users with novel synthetic targets request tailored drying grades or larger volume drums with unique liner materials. Where feasible, we match these requirements batch by batch, using in-house pilot lines to reach the right spec. Chemists in university settings may notice slight changes in crystallization patterns—direct dialogue lets us interpret these reports quickly, assigning production tweaks or advising on optimal storage. This cycle of open feedback and iterative improvement lets us ride with changes instead of falling behind.

    We run on more than data—practical experience of long-serving operators, hands-on troubleshooting, and unflinching willingness to try new approaches. Our entire team, top to bottom, knows customers by name and listens closely to understand where Citrusinine I fits into their bigger projects.

    Why the Direct Manufacturer Matters

    The difference between dealing with a full-cycle manufacturer and a distributor comes into sharp relief anytime a field issue emerges. Only firsthand production knowledge, batch-specific records, and in-house staff give the confidence to resolve issues quickly. For Citrusinine I, real users value the ability to trace every kilogram, reach directly to technical staff, and hear unvarnished details of how every improvement came to be. That sense of reliability can’t be summarized by technical specs or catalog blurbs.

    Having skin in the game changes how we view every pail leaving our dock. Owning the factory floor means owning the outcome and standing behind every shipment. Long-term relationships grow from solving real problems, maintaining open lines of communication, and improving in response to authentic feedback.

    The Road Ahead

    Citrusinine I reflects the shared knowledge of production staff, technical experts, and users in the lab and on the manufacturing line. Every year brings fresh challenges—shifts in raw material supply, evolving downstream specifications, and new requirements from regulators or customers. We face them with direct experience, a problem-solving mindset, and the accumulated lessons that only an actual manufacturer can claim.

    As markets grow and new uses for compounds like Citrusinine I continue to develop, we remain committed to supporting every end user’s success through open dialogue, solid quality, and flexibility that comes from owning every link in the production chain. This is not just a catalog number, but a daily practice of chemical manufacturing honed over thousands of runs and real-world challenges.