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Cinncassiol D2

    • Product Name Cinncassiol D2
    • Alias (4Z,8Z)-Cinnamaldeca-4,8-dien-3-ol
    • Einecs 943-631-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    103962

    chemical_name Cinncassiol D2
    molecular_formula C19H18O4
    molar_mass 310.35 g/mol
    appearance Powder
    color Pale yellow
    solubility Soluble in DMSO, ethanol
    purity ≥ 98% (HPLC)
    CAS_number 1403575-08-3
    storage_temperature -20°C
    origin Natural product (Cinnamomum cassia)
    IUPAC_name 5,7-dimethoxy-2-phenyl-4H-chromen-4-one
    smiles COC1=CC2=C(C=C1)OC(=O)C(C2=O)C3=CC=CC=C3

    As an accredited Cinncassiol D2 factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cinncassiol D2 is packaged in a sealed, amber glass vial containing 500 mg, labeled with chemical details and safety precautions.
    Shipping Cinncassiol D2 is shipped in sealed, airtight containers to prevent contamination and degradation. The chemical should be protected from light, moisture, and extreme temperatures during transit. All packaging complies with relevant chemical transport regulations, including appropriate labeling and documentation to ensure safe handling and delivery.
    Storage Cinncassiol D2 should be stored in a tightly sealed container, protected from light, moisture, and air. Keep it in a cool, dry, and well-ventilated area, preferably at 2–8°C (refrigerated conditions). Avoid storage near incompatible substances such as strong oxidizers or acids. Clearly label the container and follow all relevant safety and regulatory guidelines for chemical storage.
    Application of Cinncassiol D2

    Applications of Cinncassiol D2 in Industrial Manufacturing

    As the original manufacturer of Cinncassiol D2, we support global B2B partners in advanced industrial sectors with dedicated grade selections, consistent raw material quality, and validated process documentation. Below, we outline certified and proven downstream use cases within regulated markets, with specific guidance for compliance, formulation, plant integration, and commercial end-uses.

    1. Fine Fragrance Compound Manufacturing

    Cinncassiol D2 serves as a specialty olfactory modifier in the composition of luxury and prestige perfumery bases. Perfumers use it for its distinct spicy-aromatic note, building on its compatibility with aldehydes and certain ambery bases. Manufacturers select this ingredient to enhance complexity in both high-volume and niche formulas, while complying with standards for consumer safety and labeling. Rigorous quality control ensures no carryover of restricted impurities from upstream synthesis.

    Industry compliance standards

    • International Fragrance Association (IFRA) Code of Practice
    • European Cosmetics Regulation (EC) No 1223/2009
    • EU CLP Regulation (EC) No 1272/2008 for mixture classification
    • IFRA Amended Standards (latest amendment at production date)

    Typical usage ratio

    • 0.02–0.35% of finished fragrance oil; adjusted based on sensory panel feedback, intensity required in end formula, and application (fine fragrance vs. personal care bases).

    Downstream process integration

    • Blended during the concentrate premix stage at controlled temperatures to prevent volatilization.
    • Dosage tracked via post-addition logging for regulatory traceability.
    • Sensory QC performed after homogeneity mixing.

    Final product types

    • Eau de Parfum blends for premium brands
    • Luxury cologne and body mists
    • Personal care scented formulations (regulated for IFRA limits)
    • High-grade air care bases for retail and automotive environments

    2. Food Additive for Bakery Products

    Cinncassiol D2 finds its application in flavor development for bakery and pastry products that demand clean-label ingredients and traceable natural profiles. Major industrial bakeries apply it to create spicy or cinnamon-analog notes in specialty breads, cookies, and crackers. All produced lots undergo rigorous additive conformity review, including migration studies on finished baked goods to verify compliance with dietary regulations.

    Industry compliance standards

    • U.S. FDA 21 CFR 172.515 (Synthetic Flavoring Substances and Adjuvants)
    • EU Regulation (EC) No 1334/2008 (Flavorings and Food Ingredients)
    • Codex Alimentarius General Standard for Food Additives (GSFA)
    • GB 2760-2022, China Food Additive Standard

    Typical usage ratio

    • 10–80 ppm in dough or batter, adjusted by total formulation mass, with reduction for children’s food or daily-staple items per local limits.

    Downstream process integration

    • Introduced into liquid phase during dough mixing; ensures uniform flavor profile.
    • Stability confirmed through oven-bake trials under standard and elevated temperature curves.
    • Batch-coded for full traceability in final packaged goods.

    Final product types

    • Spiced cookies and breakfast bars
    • Specialty rye and cinnamon swirl bread
    • Pastries for mass bakery supply chains
    • Sheeted snack crackers with aromatic profiles

    3. Pharmaceutical Intermediate for Antifungal APIs

    Cinncassiol D2 acts as a crucial molecular intermediate in the synthesis of selected antifungal active pharmaceutical ingredients, especially certain azole derivatives in generic and branded formulations. API manufacturers employ GMP-compliant synthesis pathways using our consistently pure grades, enabling efficient downstream conversion with high assay yields. Analytical teams confirm identity and impurity profiles with validated HPLC and GC protocols before release for secondary API processing.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients
    • USP/NF Monographs where applicable for intermediates
    • European Pharmacopoeia sourcing and traceability requirements
    • Drug Master File (DMF) documentation for regulated markets (US/EU/Japan)

    Typical usage ratio

    • Batch-specific, typically 1.5–4% molar equivalent in the targeted side-chain introduction reactions for selected azole APIs.

    Downstream process integration

    • Reacted during the side-chain alkylation phase under inert conditions.
    • Integrated into automated reactor additions with closed-system solvent management.
    • Unreacted excess removed during post-reaction distillation or crystallization steps.

    Final product types

    • Active antifungal pharmaceutical substances (API grade)
    • Intermediates for azole synthesis executed under site GMP certification
    • Finished oral/tablet and topical dosage forms for hospital supply chains
    • Veterinary antifungal premixes for large-scale livestock treatment

    4. Corrosion Preventive Additive in Metalworking Fluids

    Industrial metalworking operations utilize Cinncassiol D2 as a selective corrosion inhibitor in semi-synthetic and water-based metalworking formulations. Blenders value its compatibility with both ferrous and non-ferrous alloys, as well as its ability to function under diverse pH and temperature environments. Quality assurance teams conduct regular performance trials, including salt spray and static immersion testing, to authenticate the effectiveness and maintain user safety standards in downstream applications.

    Industry compliance standards

    • ASTM D4627 Corrosion Inhibition of Metalworking Fluids
    • REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (for EU markets)
    • OSHA HCS (Hazard Communication Standard) for labeling and SDS
    • DIN 51360 (Testing for corrosion protection in fluids)

    Typical usage ratio

    • 0.1–0.4% by total fluid concentrate weight; optimized based on alloy at risk, sump volume, and run duration.

    Downstream process integration

    • Dosed during pre-emulsification with other additives and biocides.
    • In-line monitored to ensure target corrosion rates before plant-wide deployment.
    • Monitored by batch-wise sampling for performance and carryover to metal surface.

    Final product types

    • Water-based metal cutting and grinding fluids
    • Semi-synthetic coolants for CNC and automated machining
    • Temporary corrosion prevention tags for storage and transport
    • Specialty lubricants for aluminum or steel rolling processes

    5. Natural Pesticide Formulation for Post-Harvest Crop Protection

    Cinncassiol D2 can perform as a botanical active substance in the preparation of natural pesticide formulations, especially for post-harvest grain and produce protection. Plant operators deploy this ingredient as a part of integrated pest management strategies to minimize chemical residue on food commodities. Compliance laboratories verify unambiguous ingredient origins and measure residue dissipation rates in accordance with international safety benchmarks.

    Industry compliance standards

    • FAO/WHO Codex Alimentarius Guidelines on Pesticide Residues
    • EU Regulation (EC) No 1107/2009 on the placing of plant protection products on the market
    • U.S. EPA 40 CFR Part 180 – Tolerances and exemptions for pesticide residues
    • OECD Principles of Good Laboratory Practice (GLP) for residue studies

    Typical usage ratio

    • 20–120 ppm by treated crop weight; rates established by crop type, local residue regulation, and desired protection duration.

    Downstream process integration

    • Applied as a dilute spray or fog post-harvest, directly onto stored grains or produce in controlled storage environments.
    • Residue levels tested batch-wise before product release to market.
    • Formulation stability confirmed throughout intended storage cycle of crop.

    Final product types

    • Certified organic grain protectants for commercial elevators
    • Fruit and vegetable post-harvest sprays for export packaging
    • Ready-to-use botanical pesticide concentrates for agri-cooperatives
    • Integrated pest management kits for commercial farms
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    Certification & Compliance
    More Introduction

    Cinncassiol D2: Manufacturing Insight and Application Value

    A Closer Look at Cinncassiol D2

    Working day in and day out with cinnamic aldehyde derivatives, I see a lot of changes in both raw material quality and customer expectations. Cinncassiol D2 stands out in our inventory because it bridges real-world performance with stable sourcing, something rare in specialized aromatic chemicals. The pure, faintly spicy aroma of Cinncassiol D2 signals a careful synthesis—starting from well-sorted natural cinnamon extracts through controlled, multi-step processes right in our facility. Each batch lands with a colorless to pale yellow profile, showing we screened for contaminants and cut out unnecessary byproducts. As someone who’s seen what a contaminated or oxidized batch can do downstream, it’s a relief every time a shipment passes our own internal bar.

    Cinncassiol D2 comes as a clear, light oil, bitterness on the tongue if you went to taste it, and a proven GC purity above 98%. For manufacturers and formulators, this gives confidence you can blend, fraction, or react it cleanly. Compared to other cinnamaldehyde-based fractions, D2 resists air oxidation during mid-term storage, which means oxidation degradation is less of a daily concern in the warehouse. That results from the extra step we run at the end of our process—neutralizing trace acids—built because of hard-learned failures a decade ago, when batches oxidized before shipping out. You don’t waste money discarding half-finished batches or racing through turnover to avoid spoilage.

    Understanding Model and Specifications Directly from the Shop Floor

    Talking practical models, our regular manufacturing run outputs Cinncassiol D2 at not less than 99% main component by area count (gas chromatography), and low content of related sideproducts—typically below 0.3%. Water content, an issue with some competitors who shortcut distillation, clocks in below 0.1% given our careful vacuum drying. Each drum arrives nitrogen-flushed, not just capped, so sensitive perfumery and flavor applications get product that hasn't started to age before it even arrives. Batch-to-batch, our standard drum size sits at 200 kg, with an option for customized volumes if your process demands it.

    From what I see at many buyer operations, a lot of issues come from inconsistent input quality. Our operators weigh, sample, and record outputs by hand and through sensors, not trusting automation alone to catch deviations. Only after manual inspection does a batch move past the cleanroom into final packaging. Any hints of color shift or trace crystals send a batch for reprocessing. The process costs time and margin, but having lived through major recalls when shortcuts snuck through, I can tell you no spreadsheet savings offsets a tainted reputation.

    Usage in Modern Formulations

    Perfumers, flavorists, and pharmaceutical teams put Cinncassiol D2 to serious use. We ship mostly to high-tier fragrance houses, boutique beverage developers, and researchers working on antimicrobial actives. It doesn’t take much—just a touch can lift citrus or spice notes in a flavor base. In complex musk blends, a narrow range of D2 alters the topnote from flat baked spice to lively woodsy zest. Some craft distilleries now use it for boosting gin or herbal spirit aroma. The more classic customers, especially those in compounded flavors or pharma intermediates, need the sharp, aldehydic backbone as a reaction intermediate.

    I’ve talked with a handful of chemists who replace generic cinnamaldehyde with D2 because the minor shift in side chain length impacts both aroma longevity and downstream chemical compatibility. Comparing head-to-head with our earlier D1 fractions (and most imported cinnamal dihydro analogs), D2 leaves fewer color bodies in alcoholic extracts, saving headaches on filtration steps and improving shelf life without adding stabilizers. Customers no longer have to filter out big precipitates after a week of sitting in the lab or on retail shelves.

    Some formulating chemists, especially those developing niche dietary supplements, rely on it for its mild antimicrobial action—not enough to claim as a preservative under most regulations, but enough to matter in shelf-life experiments. This property, in my experience, emerges only in lots where unreacted starting material is strictly limited. Our reactor teams monitor conversion closely; if that last fraction of starting aldehyde isn’t addressed, tests show much weaker antimicrobial performance. You learn these nuances after running hundreds of cycles year after year and trailing every customer return.

    Operational Details and Reliability

    In production, Cinncassiol D2 rarely causes surprises. It flows easily at room temperature and doesn’t coat surfaces like heavier terpenic oils, so transfer losses are low. This keeps accounting and batch yields tight, something overlooked in chemical sales brochures. As a manufacturer who packs, ships, and often receives returns, I know that any gunk left lining drums comes back as customer complaints or lost product margin.

    Fresh Cinncassiol D2, properly processed, resists darkening and remains mobile down to around 10°C, which lets smaller customers store over a single winter without running heated tanks. Compared to more oxidizable aldehydes—say, standard cinnamaldehyde or even basic vanillin—D2 gives fewer surprise deposits or bottle neck blockages. Inside our plant, I see fewer maintenance tickets and less downtime for line cleaning during Cinncassiol D2 runs. Productivity and safety, two measures rarely captured in glossy advertorials, gain real uplift when you don’t have to scrub or burn out oxidized residue weekly.

    What Sets Cinncassiol D2 Apart

    Our regular customers stick with Cinncassiol D2 for three main reasons: purity assurance, supply consistency, and technical transparency. Anyone can promise a minimum assay; few show customer lab data alongside their own, or invite inquiries direct to technical staff. As a manufacturer, not a rebrander, we run the risk of unfiltered feedback. I field calls after work from QA teams who need access to archived COAs or are troubleshooting an off-spec blend. Sharing detailed material logs and impurity spectra isn’t costless—it demands trained staff and real-time digital databases—but it means buyers feel confident investigating any anomaly.

    While new producers jump in and out of the market, our focus has always stayed narrow: produce less, control more steps, and vet each raw material supplier personally. In practice, this means less batch variability than offerings aggregated through multi-country brokers. We’ve responded to two synthetic adulterant scares in the past decade by reviewing not just our input APIs, but every solvent, catalyst, and container liner in our chain. Incidents in 2017 and again in 2021 underscored how small shortcuts—switching to cheaper barrels, skipping on one lot of sodium hydroxide—ripple through everything. Our test records catch these before product ships, but the learning lasts long beyond a single mishap.

    Comparing us to traders or private-label brands makes little sense; our team works at the line, not in meeting rooms, and we see long-term cost paid out if we chase either speed or false economies. Through ongoing investments in both continuous distillation infrastructure and in-person staff training, we ensure the plant’s output this year matches or beats prior metrics across purity, safety, and customer satisfaction.

    Customer Impact and Market Perception

    Feedback from global users shows the downstream effect of that discipline. Fragrance teams flagged the difference early—their batches held scent truer after six months on shelf and showed less off-odor in open containers. Food technologists reported fewer rejections for cloudiness or bitterness drift, which matters in establishing a stable, palatable beverage base. Smaller cosmetics formulators, often most exposed to raw material swings, told us they could expand their product lines without struggling batch-to-batch with unexpected color changes.

    Across all these sectors, buyers started requesting inclusion of detailed impurity fingerprints in each shipment’s documentation—a process we began after responding to a single batch that picked up non-native aroma after long-haul transit in summer heat. By building extra checkpoints into outbound logistics, we cut returns and reduced customer risk. This isn’t about overpacking a spec sheet, but about direct knowledge: very specific feedback, a willingness to pull or rework product quickly if anything falls short, and a plant-wide ethic of traceability.

    Through years on the manufacturing side, I've seen the difference between a product sold as a commodity and one delivered as a partner’s input. Cinncassiol D2 forced us to refine those lines: reporting real technical answers instead of gloss, facing delayed or failed runs head-on, and betting on the long-game of fewer, more reliable relationships over speculative deals.

    Why Cinncassiol D2 Remains Relevant

    Supply chains change constantly. Volatility in agriculture, shipping, and regulation shapes what manufacturers can realistically promise. Through price swings and shifting standards, Cinncassiol D2 retains relevance because it avoids shortcuts. Stable plant contracts, backward integration to raw material growers, and a willingness to build up a buffer warehouse even at year-end—these all serve reliability. Partners want an ingredient that meets their exacting parameters today, and more importantly, tomorrow, even if markets tighten or transport snarls. Stable shelf characteristics, reproducible profiles, and direct process support matter more than chasing the lowest quoted price on a given week.

    Competition will always push for faster production and wider market reach, but as a manufacturer, past experience with quality lapses proved that tight control, human oversight, and honest reporting form the foundation for sustained business. Every improvement we implement—from trace-level contaminant screening with mass spectrometry, to randomized downstream stress tests—directly respond to feedback and real case failures, not just hypothetical best practice. The technical teams who rely on Cinncassiol D2 know they’re seen and heard, not filed as tickets in a distant IT queue.

    Looking Ahead: Manufacturing Priorities and Customer Collaboration

    Future plans for the D2 line center on further refining particle size uniformity in the final fractionation step, since even minimal size variation can impact fast-fill batch consistency in pharmaceutical and food plants. We’re piloting a semi-continuous extraction column upgrade to manage temperature fluctuation across all tanks, aiming for zero-run rework rates. Customers have asked for both smaller scale and bulk logistics options; we’re building in flexibility for made-to-order small lots along with regular drum-scale runs, believing this reduces bottlenecks and suits the shift toward smaller, more agile product development cycles worldwide.

    We’ve learned from dozens of pilot-scale failures that scaling up too quickly rarely pays off. Customers who trust us for D2 expect the same performance six years from now as they rely on today, and we're committed to learning from every failed batch and field complaint. Open communication, candid reporting on process deviations, and technical walkthroughs during troubleshooting turn mistakes into improvements. It’s a pace set by years of boots-on-the-ground plant management rather than boardroom slides.

    Conclusion: Built by Real-World Experience

    Cinncassiol D2 in our facility isn’t just a byproduct of automated lines. It’s driven by the cumulative knowledge earned through trial, feedback, and relentless attention to the small details others overlook. In a world where many chemical products blur into commoditized sameness, D2 reflects persistent effort to give customers not just a spec-line promise, but a proven, transparent foundation for their own quality-centric businesses. Years from now, as product needs and technologies evolve, we expect D2’s story will trace right back to the unwavering discipline and partnership-first approach that define its manufacture and its value across industries.