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Cinnamyl Acetoacetate

    • Product Name Cinnamyl Acetoacetate
    • Alias CINAA
    • Einecs 237-314-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    918843

    CAS_Number 7779-77-9
    Molecular_Formula C13H14O3
    Molecular_Weight 218.25 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling_Point 168-170°C at 1 mmHg
    Density 1.102 g/cm³ at 25°C
    Refractive_Index 1.547-1.550 at 20°C
    Flash_Point >110°C
    Solubility Insoluble in water, soluble in organic solvents
    Purity Typically ≥98%
    Odor Sweet, balsamic
    SMILES CC(=O)CC(=O)OCC1=CC=CC=C1

    As an accredited Cinnamyl Acetoacetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cinnamyl Acetoacetate is typically packaged in a 500g amber glass bottle with a secure, leak-proof cap and proper labeling.
    Shipping Cinnamyl Acetoacetate should be shipped in tightly sealed containers, away from heat, sparks, and open flames. It must be clearly labeled as a chemical substance and protected from moisture and direct sunlight. Transport should comply with regulatory guidelines for chemical safety, ensuring proper documentation and precautions to prevent leakage or accidental exposure.
    Storage Cinnamyl Acetoacetate should be stored in a tightly sealed container, away from direct sunlight, heat, and sources of ignition. Keep it in a cool, dry, and well-ventilated area, ideally in a chemical storage cabinet. Avoid contact with strong oxidizing agents. Ensure that storage areas are clearly labeled and access is restricted to authorized personnel only.
    Application of Cinnamyl Acetoacetate

    Applications of Cinnamyl Acetoacetate in Industrial Manufacturing

    Our facilities manufacture Cinnamyl Acetoacetate at industrial scale for integration by global partners in precise downstream production lines. The following application scenarios reflect the real-world sectors and workflows where this specialty chemical provides established value. Detailed below, you will find specific usage environments, compliance standards followed, addition ratios, stage of incorporation, and representative final goods—enabling transparent and fact-based assessment for your procurement, formulation, technical, regulatory, and supply chain teams.

    1. Fine Fragrance Formulation for Personal Care

    Fragrance compounders leverage Cinnamyl Acetoacetate as a high-impact blending note in high-end perfumery bases and luxury personal care scents, owing to its delicate sweet-floral character coupled with intrinsic stability under alcohol and mild acid/base conditions found in these products. Formulators apply this material for its ability to provide natural-warmth top notes and extend certain floral-woody bouquets, especially in compositions where complex aromatic layering is required without risking premature degradation during shelf-life or brief thermal exposures of the filling line. Adoption in major fragrance markets is supported by global regulatory acceptance, as long as compliance and toxicological limits are observed by authorized producers.

    Industry compliance standards

    • IFRA (International Fragrance Association) Amendment Guidelines
    • EU Regulation (EC) No 1223/2009 on Cosmetic Products
    • Cosmetic Ingredient Review (CIR) Safety Assessment
    • REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (European Union)

    Typical usage ratio

    • 0.05% - 1.5% of fragrance formula, variable according to perfume concentration (Eau de Toilette, Eau de Parfum) and local safety restrictions; higher ratios require specific risk assessment depending on combined allergen and sensitizer levels in the finished product profile.

    Downstream process integration

    • Incorporated into fragrance oil concentrate during combined mixing/homogenization step, prior to dilution in base alcohol or carrier solvents, with in-process GC-MS validation to monitor aromatic profile stability; never introduced directly to surfactant phase or raw aqueous mixtures to avoid partitioning issues.

    Final product types

    • Designer perfumes, luxury colognes, high-grade personal care fragrance bases (body mists, aftershaves, hand creams with perfumed actives).

    2. Flavor Ingredient in Food Additive Blends

    Food technology companies use Cinnamyl Acetoacetate as a trace additive to impart soft, mellow nuances resembling green-warm or fruity-floral notes in complex flavor systems. It is primarily used as a supporting modifier in baked goods, beverages, confectionery, and select dairy products, mainly as part of proprietary flavoring bases where stability against light and moderate heat is essential to avoid off-notes or breakdown. Regulatory acceptance is determined strictly by national and regional food additive regulations, and addition ratios are tightly capped by the functional flavor threshold and joint safety evaluations conducted by expert panels.

    Industry compliance standards

    • Food Chemicals Codex (FCC, US Pharmacopeial Convention)
    • European Food Safety Authority (EFSA) Flavoring Regulation (EC) No 1334/2008
    • Code of Federal Regulations Title 21 (21 CFR Part 172, US FDA permitted flavoring substances)
    • Joint FAO/WHO Expert Committee on Food Additives (JECFA) specification for flavoring agents

    Typical usage ratio

    • 0.001% - 0.05% (w/w) in finished foodstuffs, with upper limits set by both functional threshold and maximum permitted daily intake (Acceptable Daily Intake) from combined exposure; actual use level set at the lowest level necessary for flavor contribution, validated by sensory and analytical panel data.

    Downstream process integration

    • Added within flavor ingredient premix phase or microencapsulated flavor blends, introduced to main batch typically during the blending or emulsification sequence in food processing; never subjected to direct prolonged high heat or high pH conditions. Batch QC monitors for any potential decomposition volatiles.

    Final product types

    • Bakery flavorings, beverage essence concentrates, candy and confectionery mixes, processed dairy flavor bases (e.g., flavored yogurts and dessert toppings).

    3. Pharmaceutical Intermediates for Active Pharmaceutical Ingredient (API) Synthesis

    Cinnamyl Acetoacetate has established use in the manufacture of select pharmaceutical intermediates, particularly for producing molecules requiring the acetoacetate ester functional group as a protected synthon. GMP pharmaceutical plants integrate this material within staged organic synthesis routes to build specialized moieties included in various APIs, capitalizing on its reactivity under controlled catalytic or selective hydrolysis conditions. Regulatory oversight here is stringent due to the final molecule’s medical application, requiring traceability of all raw material supply down to batch QC, and uniformity throughout preclinical, clinical, and commercial production.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • Good Laboratory Practice (GLP) and cGMP (Current Good Manufacturing Practice, FDA/EMA/EU guidelines)
    • Pharmacopeial Monographs as relevant (USP, EP, JP where the derivative appears as a monograph or listed intermediate)
    • Qualified Person (QP) release requirements, full traceability under GxP frameworks

    Typical usage ratio

    • Stoichiometric to slight molar excess (typically 1.0–1.2 molar equivalents) in targeted catalytic coupling or acetoacetate transfer steps of the total API synthesis pathway; batch size and ratio determined by the specific molecular design and optimization during process scale-up.

    Downstream process integration

    • Fed into multi-step organic synthesis reactors at the designated functionalization step, often followed by purification (distillation or chromatography) prior to downstream derivatization or protection group cleavage. Material identity confirmed for each lot via NMR and HPLC prior to batch release.

    Final product types

    • Intermediate esters and ketone-bearing fragments for final API drug substances, particularly for synthesized compounds with protected acetoacetate functionalities or modified prodrug forms.

    4. Fine Chemicals Synthesis for Specialty Resins

    Producers of high-value specialty resins, coatings, and adhesive agents utilize Cinnamyl Acetoacetate in the production of custom monomers and crosslinkers. Its reactivity supports the creation of thermally stable networks or tailored copolymers. The targeted use is in advanced technical resin systems where subtle modification of mechanical, optical, or processability characteristics is required. Industrial resin manufacturing requires supplier documentation to meet rigorous environmental and workplace standards, as process residues can impact emissions and regulatory status of finished materials exported globally.

    Industry compliance standards

    • EU REACH (Regulation (EC) No 1907/2006) for industrial chemical use
    • United States EPA TSCA (Toxic Substances Control Act) registration
    • RoHS and SVHC (Substances of Very High Concern) absence declarations
    • Industry-specific technical standards (e.g., DIN EN ISO 9001 for quality management in chemical processes)

    Typical usage ratio

    • 2% – 7% as a crosslinking or modifier component within total monomer mix, depending on desired resin performance characteristics; exact ratio defined by mechanical and chemical property targets, validated through downstream pilot compounding trials.

    Downstream process integration

    • Added as a pre-polymerization monomer or co-monomer in batch or continuous reactor systems, typically before major initiator or catalyst addition. In-process control ensures residual monomer removal through vacuum stripping or washing prior to blending for the end-user application.

    Final product types

    • Specialty crosslinked resins for electronics, custom adhesives, high-durability coating systems, and niche composite polymers with optical or flexibility enhancements.

    5. Scented Detergent and Home Care Formulas

    Manufacturers of premium household cleaning and fabric care products deploy Cinnamyl Acetoacetate as a fragrance-enhancing raw material within scent accord blends. Its unique odorous profile is favoured for elevating “natural, fresh” olfactive perceptions in laundry and surface cleaners where fragrance longevity post-wash or during air-drying is essential. Compliance focuses on both consumer and workplace safety, including restrictions on use concentrations, and monitoring of trace fragrance allergens according to regional listing requirements for finished home care formulations.

    Industry compliance standards

    • IFRA (International Fragrance Association) detergent-specific guidance
    • EU Detergents Regulation (EC) No 648/2004, annex fragrance labelling
    • Globally Harmonized System of Classification and Labelling of Chemicals (GHS, labeling/disclosure for non-cosmetic consumer goods)
    • National poison centre notification and SDS requirements

    Typical usage ratio

    • 0.02% – 0.6% in fragrance concentrate portion of detergent or fabric care formulas; balanced against total fragrance load and volatility throughout production and post-use phases. Higher ratios undergo consumer safety review and challenge testing.

    Downstream process integration

    • Introduced within master fragrance premix, which is then dosed into detergent or softener concentrate during cold-blending or controlled temperature mixing. Final finished product QC screens for any migration, discoloration, or unexpected volatile release on storage testing.

    Final product types

    • Premium liquid laundry detergents, fabric softeners, scented surface cleaning agents, home air freshener gels and sticks.

    6. Aroma Chemicals for Tobacco Flavoring

    Cinnamyl Acetoacetate finds specialized adoption by tobacco flavor blenders who require stable, nuanced impact aroma molecules with limited volatility loss in prep, curing, or storage. It features in low-dosage flavor improve blends for certain flavored cigarettes, cigars, pipe and heated tobacco products, generally in mature regulated markets permitting added flavorings under strict ingredient transparency and toxicological disclosure schemes. Regulatory scrutiny is intense due to national and supranational product legislation and the material is clearly listed in manufacturer regulatory submissions and product notification dossiers.

    Industry compliance standards

    • EU Tobacco Products Directive (2014/40/EU) and delegated acts on flavor ingredients
    • FDA 21 CFR Part 1140 Subpart D and HPM guidance for permissible flavor additives
    • ISO 12863, Analytical methods for characteristic flavorings in tobacco
    • Local market notification and reporting (brand and product specific, e.g., Health Canada TPCR)

    Typical usage ratio

    • 0.0005% – 0.03% (w/w) in the total blended tobacco matrix or casing liquor. Actual use calibrated to overall blend goals and assessed for in-use consumer safety by qualified in-house and third-party toxicologists prior to market clearance.

    Downstream process integration

    • Added to base casing liquids or impact top note mixes during post-fermentation but pre-curing/pre-cut for cigarettes, or directly to reconstituted tobacco sheeting in non-combustible heated products. Product stability tracked by GC-FID and sensory panel review as part of finished good batch approvals.

    Final product types

    • Flavored cigarettes, cigars, pipe tobacco, fine-cut roll-your-own, and new generation heated tobacco consumables.
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    Certification & Compliance
    More Introduction

    Cinnamyl Acetoacetate: Manufacturer’s Perspective on a Niche Chemical

    Direct from the Source: Understanding Cinnamyl Acetoacetate

    Manufacturing cinnamyl acetoacetate opens a window into the precise interplay of chemistry and specialization that only a hands-on producer experiences. The production process doesn’t allow shortcuts or generic approaches—every batch reflects knowledge gained from decades of experimentation, close attention to process control, and honest assessment of what end users expect. Within our own facility, we've watched this compound mature from a novelty ingredient into an essential building block in fragrance, flavor, and specialty chemical applications. That shift didn’t happen overnight. It arises from consistent work with raw materials, refining crystallization steps, managing side reactions, and maintaining product purity—work guided by trust in scientific rigor more than market trends.

    Cinnamyl acetoacetate, which carries the structural signature of both a cinnamyl and an acetoacetate group, stands apart in its ability to bridge the world of creative aroma synthesis and specialized chemical modification. In fully realized form, it becomes a pale to light yellow liquid. We’ve tested for water solubility, density, and boiling point across hundreds of runs, always seeking the best ratio between manageability and reactivity. The distinctive sweet, balsamic, and floral aroma underpins why this compound attracts professionals in perfumery and taste modulation—the unique structure interacts differently than standard intermediates, and results bear out that investment in its manufacture is well justified.

    Hard-Earned Lessons From the Synthesis Floor

    Our chemists navigate each step of cinnamyl acetoacetate’s synthesis with pragmatic skill. Start with carefully chosen cinnamyl alcohol, control every variable in acetoacetylation, and design the purification system to avoid contamination and byproduct formation. This kind of hands-on knowledge never flatlines. Bringing the process up to multi-ton scale exposed bottlenecks that only direct manufacturing reveals. Raw material supply chain hiccups, batch-to-batch color consistency, and downstream handling are just a few examples. Nobody working the reactors is content with a single certificate of analysis; in-house monitoring, GC-MS traces, and olfactory validation build real confidence.

    With each batch, our operators watch for temperature spikes, evaluate side reactions, and constantly refine yield. Only repeated hands-on work reveals that freshness of cinnamon-derived raw materials subtly changes yield profiles and that acid-neutralization must balance thoroughness against over-extraction of wanted fractions. We see the consequences of fiddling with process times, input grades, or ambient humidity every day. The chemical never lets you forget that it has personality—even minor process deviations echo in the product consistency.

    Unique Features That Set Cinnamyl Acetoacetate Apart

    There’s a reason why perfumers and flavorists seek out cinnamyl acetoacetate and not just any acetoacetate or cinnamyl derivative. Our direct manufacturing experience underscores those differences sharply. Standard acetoacetates tend to carry a sharp, fruity, or doughy note, lacking the floral richness this compound imparts. Cinnamyl alcohol alone brings crisp, spicy-sweet warmth, but fusing it with the acetoacetate backbone grants added depth—a smoother, rounder character that persists and blends seamlessly into both top and middle notes.

    Through side-by-side comparisons, it becomes clear that cinnamyl acetoacetate offers a far more persistent odor profile and richer mouthfeel in edible flavor applications than simpler esters. Blending and stability work benefits from its molecular design: it holds up well in both water-based and oil-based solutions, retains its sensory character under mild heat, and imparts resilience during extended storage.

    We’ve partnered with industry labs to stress-test formulations. Formulators report that substituting this chemical into classic floral bouquets, chypres, or gourmet notes results in products that smell fresher for longer and feel less “thin” or “faint” at trace dosages. Applications in soaps, detergents, and candles built on first-hand partnerships also highlight the long-lasting aroma, low volatility, and easy incorporation. Every improvement stems from feedback collected over repeat industrial-scale campaigns and real-world trials, not just lab bench simulations.

    Applications Shaped by Manufacturing Know-How

    Practical applications for cinnamyl acetoacetate span far beyond simple perfumery. Direct users—those who order drums and tankers, not small sample bottles—find value in its reliability and sensory profile. We supply to fine fragrance compounding plants, flavor houses experimenting with pastry and confection formulas, and specialty chemical makers focused on aroma-intensive home care products. The most obvious impact is in perfumery, where a measured dose imparts a honeyed, slightly spicy backdrop that accentuates floral, amber, or green notes.

    In our own trials with soap manufacturers, this ingredient withstands alkaline saponification better than many related chemicals. That means the fragrance lasts on-fabric and on-skin. Flavor houses find it ideal for enhancing sweet, baked, or fruity profiles, adding the faint impression of stewed fruit or vanilla warmth without overpowering the original blend. Professional chefs and product developers seeking clean-label options appreciate knowing the manufacturing route and source chain behind the product. It’s much easier to back an ingredient when the people behind it answer technical questions openly, share process deviations, and supply authentic batch data.

    Technical teams in our partner companies confirm cinnamyl acetoacetate delivers stability in emulsified flavors for beverages, ice cream, and bakery fillings. Its solubility profile—verified through repeated batches, documented in real-world QA paperwork—ensures seamless dissolution into fatty or watery matrices. The chemical structure helps retard off-note development during shelf life assessments, a detail that has made it a favorite for long-term flavor infusions and high-intensity perfumery bases.

    Tales from the Factory: Real-World Challenges and Insights

    Scaling up this product hasn't always come easy. Over the years, supply chain interruptions, global regulatory shifts, and new environmental guidelines forced us to adapt. Sourcing quality cinnamyl alcohol, for example, means constant vigilance. Unanticipated impurity spikes in raw deliveries had a measurable impact on final odor and shelf stability. In-house testing, including GC-MS and HPLC runs, helped flag these shifts before they could affect shipments. Nobody who spends long hours in the plant overlooks the importance of robust sourcing networks and redundant storage protocols.

    Handling effluent from acetoacetylation processes carries its own environmental and regulatory responsibilities. We’ve invested in closed-loop solvent recovery and advanced filtration—not because a regulator demanded it but because we know that plant downtime for waste handling costs more than proactive design. New workers sometimes wonder why so many alarms and checks are built into the continuous reactors; the answer is always the same: prevention beats remediation. Any quality deviation in the blend reflects straight back on our field teams—there’s no hiding behind paperwork.

    Direct dialogue with end users shapes how our factory adapts. Perfumers once reported intermittent faint “burnt” notes in specific lots—traced back to a singularly humid production run impacting intermediate storage. We now maintain dehumidification protocols year-round and track micro-climate data shift-by-shift. Flavor houses periodically flag subtle taste deviations in high-acidity matrices, leading us to revalidate extraction protocols. The dialogue feeds right back into process tweaks, auxiliary filtration, and documentation. Factory workers talk about those experiences as badges of honor because each fix means more trust, fewer complaints, and a better product in the long run.

    Points of Difference: Cinnamyl Acetoacetate Versus the Alternatives

    Choosing to incorporate cinnamyl acetoacetate, as opposed to structurally similar chemicals, comes down to functional benefits realized in daily formulations. As manufacturers, we see requests for lower volatility, deeper sweetness, and longer aroma retention. Comparing it with basic acetoacetates or cinnamates, the differences in volatility, tenacity, and olfactory complexity stand out sharply. Cinnamyl alcohol works for brighter top notes but fades quickly, where our compound delivers slow release and a more rounded finish.

    Synthesizing both types in parallel, we’ve noticed cinnamyl acetoacetate forms blends with better shelf stability and color fastness, which pleases both regulatory auditors and creative teams. The ability to hold its character under mild thermal load and UV exposure gives clients confidence that their end products will survive transport and display conditions. In soap and detergent work, it survives the caustic challenge better than many analogues—a fact discovered only after extensive, direct test batches shipped to clients around the globe.

    Feedback from flavor chemists reveals another major plus: reduced risk of disagreeable “edge” or harsh flavor development under high-sugar or acidic conditions. This comes from years of process refinement, careful raw material pairing, and iterative feedback loops. It takes long-term collaboration with flavorists, not just quick transactional sales, to refine a portfolio of reliable, high-output batches.

    Supporting Facts and Vision for the Future

    Cinnamyl acetoacetate’s role in fragrance and flavor design keeps evolving as market preferences shift and new blends emerge. From our perspective as actual manufacturers, the difference between product lines rests on traceable supply chains, consistent downstream partner feedback, open batch records, and an institutional memory built on solving problems rather than chasing fads.

    Our factory investments target not just output volume but improved process transparency. Each year, we upgrade solvent recovery, implement inline analytical controls, and retrain staff on new environmental protocols. Compliance with food and fragrance safety typically means documentation as detailed as the product itself. Being able to point to archived batch data, validate positive release samples, and show real analytical results strengthens our partners’ regulatory submissions—and it builds lasting trust.

    We maintain direct relationships with raw material producers to buffer against global supply volatility. Experience reminds us that every market shock—be it raw material embargo, logistics disruption, or regulatory overhaul—tests the resilience of production systems and customer partnerships. We’ve weathered these shifts, not by scaling back, but by emphasizing “manufacturing know-how” as a competitive asset.

    Our lab teams keep detailed performance records for new application areas: longer-wearing personal care products, natural food enhancement, and even compliant encapsulation for home care. Direct customer feedback, not just lab tests, guide incremental tuning in process parameters and QC schemes.

    Potential Solutions to Industry Challenges

    The most asked-for improvements from our clients focus on environmental impact mitigation, traceability, and tighter compatibility with a broad range of formulation matrices. We address environmental burdens not through token gestures, but through investment in solvent recycling, waste minimization, and renewable feedstock exploration. These aren’t marketing taglines; they’re strategies that keep compliance costs low and production sustainable.

    Traceability means more than end-to-end lot tracking. We log details of raw origin, intermediate QC checks, storage and handling details, and even shipping temperature data. Traceable processes reduce recall risk and build regulatory credibility. Manufacturing transparency—documented through accessible, real-time batch records and traceable ingredient networks—delivers the kind of assurance big brands and regulators expect.

    Compatibility with newer application trends (such as natural bases, hypoallergenic products, and low-VOC standards) depends on fine tuning synthesis purity, residue management, and byproduct minimization. We respond by running pilot scaleups, challenging raw material vendors to improve their purity, and maintaining a rolling program of application-specific stability testing. Clients who’ve faced last-minute product reformulations due to ingredient trace concerns see direct value in this approach.

    Looking Ahead: Earning Trust with Every Lot

    The story of cinnamyl acetoacetate at our facility doesn’t stop at the loading dock. Every container shipped out carries not just an ingredient but decades of manufacturing experience, troubleshooting, and trust-building. Those who formulate with our product expect technical cooperation, open feedback channels, and honest answers to challenging questions. We see our role extending beyond production—we educate, troubleshoot side-by-side, validate changes, and provide direct insight into technical, regulatory, and sensory aspects of each lot.

    We invite our end users—perfumers, flavorists, analysts, procurement managers, and safety auditors—to engage us in technical dialogue, on-the-ground audits, and collaborative innovation. No amount of digital literature replaces the value of direct conversation and real sample testing at scale. Each relationship started on a basis of transparency, and every future collaboration will grow from demonstrated reliability, shared learning, and the mutual aim to bring safer, more distinctive fragrance and taste experiences to people everywhere.

    Through continued investment in smarter production, open communication, and scientific integrity, we aim to ensure cinnamyl acetoacetate remains a trusted, long-term solution for next-generation product developers.