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Calcium Β -Hydroxyl Β -Methylbutyrate

    • Product Name Calcium Β -Hydroxyl Β -Methylbutyrate
    • Alias HMB
    • Einecs 248-953-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    952056

    chemical_name Calcium β-Hydroxy β-Methylbutyrate
    abbreviation Ca-HMB
    molecular_formula C5H9CaO3
    molecular_weight 172.20 g/mol
    appearance White crystalline powder
    solubility Soluble in water
    odor Odorless
    taste Slightly bitter
    CAS_number 135236-72-5
    stability Stable under recommended storage conditions
    pH_of_solution Approx. 6.5-8.0 (in water)
    storage_conditions Store in a cool, dry place

    As an accredited Calcium Β -Hydroxyl Β -Methylbutyrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, opaque plastic bottle containing 100g of Calcium β-Hydroxy β-Methylbutyrate, labeled with chemical name, purity, safety, and handling instructions.
    Shipping Calcium β-Hydroxy β-Methylbutyrate is shipped in tightly sealed, moisture-resistant containers to maintain stability and prevent contamination. It is typically transported as a powder, labeled according to regulatory guidelines, and should be kept in a cool, dry environment. Appropriate documentation accompanies each shipment to ensure safe and compliant delivery.
    Storage Calcium β-Hydroxy β-Methylbutyrate should be stored in a tightly sealed container, away from moisture and incompatible substances. Keep it in a cool, dry, and well-ventilated area, protected from direct sunlight and heat sources. Ensure proper labeling and avoid storage near acids or oxidizers. Follow all relevant safety guidelines and local regulations for chemical storage.
    Application of Calcium Β -Hydroxyl Β -Methylbutyrate
    Purity 98%: Calcium Β -Hydroxyl Β -Methylbutyrate of 98% purity is used in clinical nutrition supplements, where it promotes increased muscle protein synthesis. Particle Size D90 < 50 μm: Calcium Β -Hydroxyl Β -Methylbutyrate with a particle size D90 less than 50 μm is used in oral tablet formulations, where it ensures rapid dissolution and absorption. Molecular Weight 248.27 g/mol: Calcium Β -Hydroxyl Β -Methylbutyrate with a molecular weight of 248.27 g/mol is used in pharmaceutical manufacturing, where it provides accurate dosing and bioavailability. Stability Temperature up to 60°C: Calcium Β -Hydroxyl Β -Methylbutyrate stable up to 60°C is used in sports nutrition products, where it maintains efficacy during storage and transport. Water Solubility >95%: Calcium Β -Hydroxyl Β -Methylbutyrate with water solubility greater than 95% is used in liquid dietary supplements, where it enables homogeneous mixtures and easy administration. Assay ≥99.0% (HPLC): Calcium Β -Hydroxyl Β -Methylbutyrate with an assay of ≥99.0% by HPLC is used in clinical trials, where it ensures consistent and reliable study results. Residual Solvent < 0.1%: Calcium Β -Hydroxyl Β -Methylbutyrate with residual solvent below 0.1% is used in pediatric formulations, where it reduces toxicity risks and enhances safety. Melting Point 180-185°C: Calcium Β -Hydroxyl Β -Methylbutyrate with a melting point of 180-185°C is used in granule production, where it provides thermal stability during processing. Bulk Density 0.60 g/cm³: Calcium Β -Hydroxyl Β -Methylbutyrate with a bulk density of 0.60 g/cm³ is used in capsule manufacturing, where it enables precise volume filling and uniform dosage. Shelf Life 36 months: Calcium Β -Hydroxyl Β -Methylbutyrate with a shelf life of 36 months is used in global distribution of nutritional products, where it ensures long-term storage without degradation.
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    Certification & Compliance
    More Introduction

    Introducing Calcium Β-Hydroxyl Β-Methylbutyrate: From Our Production Floor to Your Application

    Rooted in Real Manufacturing: Our Approach to Calcium β-Hydroxy β-Methylbutyrate

    Our years of hands-on production have shaped every batch of Calcium β-Hydroxy β-Methylbutyrate (CaHMB) that leaves our plant. We aren’t offering anonymous white bags pulled from some unknown warehouse shelf. Instead, we craft CaHMB from end to end, with chemists and technicians who know how raw material quality, temperature curves, and process controls affect the final product. At every stage, we have our boots on the ground, smelling, measuring, and verifying. We see everything, from the way humidity in the air changes drying rates to the subtle color cues indicating a process anomaly. This matters because CaHMB is not just a commodity – every step matters to its purity and consistency.

    Commitment to Raw Material Selection

    Careful raw material purchasing lays the foundation. The organic acids we choose come only from suppliers whose facilities we audit directly. The calcium base isn’t just food-grade, it’s selected for its solubility and reaction efficiency in our reactors. We don't buy the cheapest starting material simply to hit an internal specification; we monitor calcium content, heavy metal trace levels, and contaminant markers at the door. Our team rejects multiple shipments each year for failing even one variable. Process reliability grows out of this kind of discipline.

    Our Controlled Synthesis: Details Matter

    We don’t run a giant chemical soup that spits out variable white powders. Every production run follows detailed thermal profiles, continuously monitored pH adjustments, and staged addition of β-hydroxy β-methylbutyric acid. A digital control system logs process steps to maintain repeatability. Operators calibrate scale feeds and check for crystalline phase by FTIR analysis themselves, rather than relying on spot checks from afar. Every time a valve is turned or a batch is transferred to drying, the production engineer documents the decision. These controls make a difference you can taste, see, and test for in well-made CaHMB: low impurity, expected solubility curves, and no off-odors.

    Specifications Define, but Experience Delivers

    CaHMB offers more than a long chemical name. Its typical molecular formula sits at C5H9CaO3, with the calcium atom neatly coordinated, forming a free-flowing white powder. Particle size typically ranges between 80-120 mesh, finer than most diet supplement excipients. Loss on drying stays well below 1%, as confirmed by our in-house gravimetric ovens, and actual calcium content rarely strays outside 13.5-14.5% by mass. We back these values up with near-daily batch analysis (both HPLC and titration methods), not just a one-time certificate. We don’t find it acceptable for CaHMB to contain extraneous ammonium, chloride, or residual solvents. Each batch QC run, at a minimum, screens for conceivable cross-contaminants from other lines in our plant. We have seen competitors cut corners here and watched their batch recalls later.

    Usage: Why Reliable CaHMB Matters to Application

    Our CaHMB doesn’t disappear into the background of your formula. Athletes, health-conscious consumers, and clinical users want CaHMB for muscle recovery, preservation, and support. Many see it as a key to reducing catabolic muscle loss, promoting synthesis, and supporting overall muscle function in aging. Usage often involves blending into tablets, capsules, or direct powder servings. Our job is to make that blending trouble-free. A powder with inconsistent particle size or odd moisture content clumps up in feeders and changes tablet hardness. Excess acidity throws off flavor, especially in powdered nutrition blends. Our fine, free-flowing powder dissolves cleanly in solution, fitting manufacturers who demand reliability in every batch.

    We know how improper drying ruins solubility and flavor. Our experience with moisture analysis, color comparison by eye, and texture checks with gloved hands means no batch leaves our facility until it passes both instrument and human inspection standards. We have tossed entire lots for slight off-tastes or unexpected odors, even when lab numbers stay within spec, because the real-world user notices those details.

    Clinical applications push us even harder. Many buyers expect CaHMB not just in general nutritional blends, but in critical care protein support. Hospitals, skilled nursing facilities, and supplement companies cannot afford batch-to-batch variation. We receive direct feedback: a bit too much residual solvent or calcium variation from one drum to the next becomes an immediate phone call. We respect our buyers who depend on our vigilance, and our willingness to listen forms the backbone of our improvement culture.

    How Our CaHMB Stands Apart in the Market

    Dozens of CaHMB powders circulate around the globe. We have analyzed plenty in our lab. Generic products often show inconsistent color, ranging from white to faintly yellow. We have even encountered fake CaHMB where calcium levels barely hit 10%, meaning there’s significant dilution or mixing with filler. Some products present with detectable volatile organic residues, hinting at unfinished or sped-up production.

    We don’t just say, “Pure, high-quality CaHMB” and leave it there. We differentiate through measurement and vigilance. Our average purity regularly exceeds 98% by HPLC. Water content stays where it should, which not only makes handling easier but extends shelf life and prevents caking in storage. Every lot ships only after passing a metal contamination screen, targeting levels well below internationally-recognized thresholds, including the ones set by the FDA and European Pharmacopeia.

    Unlike CaHMB from intermediaries piecing together powders from multiple sources, our outbound drums carry a consistent odor, feel, and dispersion profile. Taste panels drawn from our own staff regularly sample dissolved CaHMB and provide feedback directly to our quality and operations teams – an extra step we believe most others skip. We reject off-tasting lots, even if they pass instrumental analysis, because final product perception depends on these small details.

    Beyond the Label: The Human Factor in Manufacturing

    Decades in chemical manufacturing haven't just armed us with data, but with seasoned professionals who know a flawless batch doesn’t come down to one lever or one lab test. We’ve faced blocked filter lines, temperature swings in the middle of a critical drying step, and supplier slip-ups that could have jeopardized an entire production run. Our team resolves issues hands-on, shutting down a process entirely rather than risking impurity or out-of-spec product. Our logs are filled with stories of walking the production floor with flashlights at midnight, troubleshooting issues as they emerge, and solving problems before they leave the building – not after customer complaints flood our inbox.

    The precision behind every kilo of CaHMB we ship grows out of this on-the-ground vigilance. Manual reconciliation of input and output, visual inspections, and a healthy skepticism for “good enough” have saved us from headaches more than once. In an industry increasingly reliant on automation, the human element—skilled judgment applied batch after batch—gives us an edge machines alone cannot replicate.

    Why Not All CaHMB Is Created Equal

    Some manufacturers flood the market with lowest-cost CaHMB, ignoring factors like raw material traceability, batch uniformity, and post-synthesis cleaning. We have witnessed imports leach flavor or carry a sharp, medicinal taint, caused by poorly controlled mother liquor composition or rushed filtration. Our experience with supplier audits tells us that even clean-looking documentation doesn’t guarantee a reliable end product. Photos and third-party COAs from resellers only show what marketing wants you to see, not the buried realities of material handling and cross-line contamination.

    We take accountability for every drum. Our facility’s quality books contain records tracking raw inputs directly to their final lots. Real clean rooms, real batch logs, real mitigate steps for when a temperature spike threatens a reaction’s completion. We know the staff who record these details, and they can point to specific equipment runs, even years later. This chain of expertise removes guesswork for any food, supplement, or clinical customer.

    The Science Behind the Choice: CaHMB vs Other Supplements

    We created our process to fit β-hydroxy β-methylbutyrate because not all nutritional calcium salts provide the same results. Standard calcium compounds, like calcium carbonate or citrate, primarily supply calcium without the muscle-protecting properties consumers associate with CaHMB. From published research and ongoing feedback, CaHMB stands out for its dual action – it delivers bioavailable calcium but, more importantly, provides HMB, a metabolite recognized for reducing protein breakdown and supporting lean mass. Clinical trials commonly use our exact form, not alternative calcium salts.

    Producing the right crystalline form matters too. A powder mixable in a sports shake must not leave sediment or clump. The beta-hydroxyl beta-methylbutyrate core unlocks both solubility and biological uptake, making CaHMB preferable for specific muscle metabolism applications. We focus on batch control and analytical checks because inadequate synthesis or poor neutralization leads to low-bioavailability variants that underperform.

    Safety, Compliance, and Continual Improvement

    Our responsibility does not stop at batch testing. Our regulatory team keeps tabs on emerging national and international expectations for purity, labeling, and permissible trace contaminants. Updated regs have shifted our heavy metal panels, our regular hygiene protocols, and our approach to sampling retained lots for periodic rechecking. Our in-house documentation prevents the slip-ups we’ve seen at peer sites, where one missing check can mean regulatory pain months later.

    Beyond standard COAs, we’ve opened our factory to third-party audits from global supplement brands, nutrition companies, and QA squads. Input from external experts encourages us to challenge our own status quo. Corrective actions are enrolled immediately if improvement is identified, with management oversight ensuring nothing slides through unnoticed. Continuous improvement culture is not a slogan; we budget annually for plant investment, staff cross-training, and new instrumentation. The resulting CaHMB reflects this mindset: reliable, safe, and ready for applications that demand more than basic “chemical grade.”

    Meeting Customer Needs, Not Just the Market Minimum

    Customers tell us what works and what doesn’t, and we listen. Anyone purchasing CaHMB at scale will encounter problems if the wrong powder arrives. Whether you’re blending high-throughput supplement tablets or preparing clinical nutrition sachets for hospital patients, you don’t want variable particle size, moisture, or off-flavor disrupting your process. We encourage customers to visit, inspect, and test our CaHMB in their own lines before finalizing any order. Our technical staff welcomes challenge trials and provides insights learned from earlier customers in similar applications.

    From our end, we have adjusted drying curves, introduced re-screening steps, and substituted higher quality filtration media following direct application feedback. We run mock-mixing sessions to simulate real-world blending. Just this year, our team reformulated a batch’s downstream processing after one customer flagged a tendency for caking when exposed to minor humidity. Solving those problems isn’t theoretical for us – it’s a reflection of being in real-world manufacturing, not just sales.

    Outlook: Trusted Supply for an Evolving Market

    Demand for reliable CaHMB continues to grow as both consumer and clinical communities appreciate its role in muscle support, recovery, and preservation. Nutritional science isn’t static; product formulations and delivery systems continue to evolve. As new direct-to-patient applications, higher-throughput sports powder lines, and research-based clinical formulas launch, the bar for CaHMB quality and batch reliability rises.

    Meeting this demand means maintaining rigorous process controls, transparent batch documentation, and a hands-on attitude that recognizes real-world production isn’t as simple as copying spec sheets. We have learned that even small process changes alter performance in use. By sticking close to our production staff, monitoring global regulatory shifts, and inviting critical customer examination, we keep our CaHMB future-ready.

    Final Thoughts: From Our Plant to Your Product

    At its best, CaHMB offers more than a chemical entry in a catalog. It offers functional support for end-users who count on true batch reliability – from hospital nutrition programs to high-performance athletes. Through years of troubleshooting, optimization, supplier vetting, and customer problem-solving, we have built a CaHMB supply not just on paper, but on real manufacturing experience. Our confidence in this product stems from what we see, measure, and fix every day in-house. Those looking for more than a generic powder find an experienced partner in us.