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Benfluorenol

    • Product Name Benfluorenol
    • Alias Tetrahydronaphthalimide
    • Einecs 226-356-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    VTB
    Specifications

    HS Code

    561367

    Name Benfluorenol
    Iupac Name 6,9-dihydroxy-2-(N,N-dimethylamino)-9,10-dihydro-5H-benzo[a]phenoxazine
    Molecular Formula C21H19NO2
    Molecular Weight 317.38
    Cas Number 15301-52-7
    Appearance White to off-white powder
    Drug Class Antitussive
    Melting Point 169-170°C
    Solubility Soluble in organic solvents
    Synonyms Aflunoxan; Benfluorexol

    As an accredited Benfluorenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A sealed amber glass bottle containing 25 grams of Benfluorenol, labeled with chemical information, hazard warnings, and manufacturer details.
    Shipping Benfluorenol is shipped in tightly sealed containers, protected from light and moisture, and labeled according to chemical safety regulations. Transport complies with local, national, and international guidelines, ensuring secure handling as a laboratory chemical. Safety Data Sheets accompany the shipment for proper storage and hazard information upon receipt.
    Storage Benfluorenol should be stored in a tightly closed container, kept in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances like strong oxidizing agents. Protect it from light and moisture. Ensure the storage area is secure and clearly labeled, and follow standard laboratory safety protocols for handling chemicals.
    Application of Benfluorenol
    Purity 98%: Benfluorenol with purity 98% is used in pharmaceutical synthesis, where it ensures high reaction yield and minimal by-product formation. Melting Point 192°C: Benfluorenol with a melting point of 192°C is used in active pharmaceutical ingredient formulation, where it provides thermal stability during processing. Molecular Weight 232.29 g/mol: Benfluorenol with a molecular weight of 232.29 g/mol is used in drug delivery systems, where it facilitates accurate dosing and predictable pharmacokinetics. Particle Size <10 µm: Benfluorenol with particle size under 10 µm is used in tablet manufacturing, where it improves blend uniformity and dissolution rate. Stability Temperature 80°C: Benfluorenol with a stability temperature of 80°C is used in extended-release formulations, where it maintains chemical integrity during heat exposure. Viscosity Grade Low: Benfluorenol with low viscosity grade is used in injectable formulations, where it allows ease of administration and consistent suspension. Residual Solvent <0.05%: Benfluorenol with residual solvent below 0.05% is used in pediatric medication development, where it meets stringent safety regulations and improves patient tolerance. UV Absorbance 280 nm: Benfluorenol with UV absorbance at 280 nm is used in analytical method development, where it enables precise quantification and quality control. Moisture Content <0.2%: Benfluorenol with moisture content under 0.2% is used in lyophilized powders, where it prevents hydrolytic degradation and extends shelf life. Chiral Purity >99%: Benfluorenol with chiral purity above 99% is used in enantioselective synthesis, where it produces optically pure drug intermediates.
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    Certification & Compliance
    More Introduction

    Benfluorenol: From Our Plant to Your Laboratory

    Plenty of chemists search for certainty. They want a compound with a clean spectrum, one they can trust every time they open a fresh bottle. In more than two decades spent working on the synthesis and refinement of specialty chemicals at our facility, I’ve seen the value of reliable benfluorenol firsthand. Reactions that looked simple on paper sometimes produced unpredictable results, and much of that came down to impurities or the wrong polymorph. That’s why every batch that leaves our plant reflects the same single point of truth—the batch record, the HPLC trace, the NMR signature. Years ago, benfluorenol might have been a pure research curiosity, but as the field matured, so did expectations around consistency and transparency.

    Trusted Production, Transparent Origins

    Benfluorenol isn’t just another white powder on the shelf. Every kilogram begins with the same investment in raw materials, careful selection of each upstream reagent, and a documented journey that follows it from our reactor to customer shipment. We don’t subcontract or outsource intermediary steps. That means we know not just the lot number but the process behind each step — including challenges unique to benfluorenol. Some intermediates require strict temperature control to avoid unwanted side products. Any old process might pass a cursory TLC, but under NMR or mass spec, trace byproducts become hard to ignore. Over the years, we’ve built a controlled environment specifically for maintaining the reactivity of fluorene cores. Our drying rooms control environmental factors like humidity, and our ovens never see another compound group on the same day. Small habits prevent big headaches.

    Technically, chemists classify benfluorenol as a polycyclic aromatic alcohol. Laboratory literature usually describes it as a solid, off-white to pale yellow, with a melting point within a narrow range. When processed at our site, the material consistently falls within this window, batch after batch. Some competitors handle drying and packaging through third parties, but every stage here relies on our own trained staff. Over time, this approach cut down on contamination and allowed for more flexible scale-ups. We notice differences between lots when someone takes shortcuts with storage or tries to minimize solvent washes. There’s a temptation in volume chemical manufacturing to automate away steps, but the extra passes through activated carbon or careful crystallization control really matter for a molecule like benfluorenol. Certain trace organic contaminants, undetectable to the naked eye, interfere with research reproducibility or cause downstream synthesis problems. Our methods, developed long before I joined the team, set a higher bar and have done so across dozens of customer audits.

    Model and Specifications

    In our operation, we define benfluorenol by the structure that matters to working chemists: C13H10O, more specifically, 9-hydroxyfluorene. Chemical models may look abstract, but in practice, improper characterization leads to customer complaints. Over the years, we faced questions about isomer content or percent composition of residual solvents. With each challenge, we refined our process controls. Today, every batch achieves greater-than-99% purity by HPLC, with tight limits on water content and residual solvent levels. Our standard product leaves little room for debate. Spectroscopic fingerprints back every label. We found that including a few supporting pages of raw spectrum actually reduced back-and-forth requests between our technical team and research customers, especially those optimizing sensitive assays.

    Not all benfluorenol is created equal. The market holds small samples intended for classroom demonstration and larger batches for heavy-duty industrial research. We commit to a unified specification, whether shipping grams or kilograms. Some labs want a specially micronized variant. We studied the effects of milling and packaging on compound stability and found that finer grades require air-tight packing and quicker turnaround times, or else they risk oxidative yellowing. Getting this right means less hassle for customers and fewer returns. We don’t ship grades that lose integrity on the shelf or reveal cosmetic changes under standard laboratory lighting. Consistency, even at a granular scale, makes experimentation and scale-up easier. Years ago, a customer pointed out that even slight variations in melting point foreshadowed bigger problems in multistep organic syntheses. That lesson stuck with our team, and today we routinely over-test new lots before clearing them.

    Usage Patterns and Real Laboratory Impact

    Benfluorenol’s value lies in its reactivity. Researchers test everything from photochemical processes to medicinal targets on its stable polycyclic scaffold. Out in the synthetic world, I see chemists using benfluorenol as a building block for more ambitious architectures: rigid ligands, organic electronics, even rare charge-transporting polymers. Our compound usually finds itself on the laboratory bench, weighed and added to reaction vessels for condensation, cross-coupling, or selective oxidation reactions. In pharma, it sometimes kicks off library synthesis. In materials science, it’s a precursor to functionalized devices. I hear frequently from clients who use it for fluorescence-based measurements. Purity turns out to be a deciding factor there, since even small amounts of fluorescent impurities introduce data ambiguity.

    Most applications demand clear solubility, often in common organic solvents like DCM, ether, or toluene. Some researchers want to modify conditions, introducing benfluorenol to a less polar or more challenging solvent system. Our production team knows which impurities will alter solubility curves and at what concentrations, based on batch records and prior analytical work. In my own experience, careful washing and drying steps seem like simple details, but they determine whether benfluorenol delivers reliable NMR spectra or creates new layer separations in a test flask. Customers sometimes request tailored forms—coarser crystals for slower dissolution, finer powders for rapid mixing. Deciding which to use involves tradeoffs and depends on downstream needs, so we work alongside researchers to match format with function.

    Benfluorenol Compared to Other Polycyclic Alcohols

    Polycyclic aromatic alcohols form a distinct group—benfluorenol sets itself apart from relatives like naphthols or biphenyl alcohols. From my perspective on the production line, subtle changes in ring structure create tangible differences in handling and performance. Benfluorenol’s fluorene backbone influences both lipophilicity and photochemical stability. Compared to naphthols, benfluorenol shows less propensity for air oxidation, provided that storage avoids direct sunlight and persistent air exposure. Labs working with benzyl alcohols often ask us about the risk of peroxide or aldehyde formation, but the fused aromatic framework in benfluorenol reduces these hazards under typical handling protocols.

    People sometimes treat their aromatic alcohols as interchangeable, but over time, repeated substitutions with cheaper compounds reveal limitations. Benfluorenol’s distinct UV-vis absorption properties support specialty analytical work, especially where photochemical response matters. Even in our own checks, switching to a similar compound for quality control can muddy the readings or lead to unanticipated byproducts in multistep synthesis. From a production viewpoint, process yield and overall batch safety look different: benfluorenol resists acid-catalyzed hydrolysis better than closer relatives lacking the rigid fluorene core. That translates into better stability before customer use and easier management of waste streams at scale.

    Beyond industrial chemistry, I see university labs tune process parameters to exploit the particular characteristics of benfluorenol’s core. Students comparing synthetic outcomes between benfluorenol and its isomeric or analog relatives often report differences in photoluminescence or solid-state packing. R&D teams tell us these differences matter in new molecule development, especially as they pursue optoelectronic devices, specialized coatings, or long-wavelength dyes. Over the years, we gathered feedback that highlighted the limits of substitution—some candidate replacements lack the spectral purity that benfluorenol delivers, leading to months lost in backtracking or reworking old methods.

    Delivering Stability and Quality

    We believe true chemical reliability comes from handling every aspect of production ourselves. Our benfluorenol never crosses into unknown hands—our team monitors the identity, quality, and traceability of each batch as it passes through synthesis, purification, drying, characterization, and packaging. The learning curve never really ends. I remember a time when a single packaging error—a mislabel, a compromised bag, an incomplete drying cycle—forced a full recall and a slew of hurried emails to researchers counting on on-time delivery. That kind of disruption isn’t just a logistical hassle; it clouds the reputation earned from years managing the full life cycle of a specialty compound.

    Across our team, we train new staff on the value of process records and attention to detail. Old hands in the business remember projects delayed by a single rogue solvent peak; new staff add the perspective of leaner, more responsive supply systems. Our staff meetings include data reviews—a habit picked up after a batch once failed and nobody could trace the missing purification step. We learned that scheduled reviews and performance feedback improve not only yield, but confidence in the finished product.

    Over time, our process chems found that benfluorenol can handle modest variations in environmental conditions better than some polyaromatic relatives, but truly high yields and purity demand unbroken attention to reactor conditions. Customers tell us they appreciate phone support from people in the lab, not outsourced agents. When someone calls with a technical question, I can reference the day’s production notes, dig into the origin of a spectral impurity, or suggest alternate workups in language that resonates with bench chemists. Years in the field taught me that success in specialty chemicals comes less from fancy marketing and more from consistent delivery and direct feedback.

    Meeting Demand and Addressing Challenges

    Static demand for benfluorenol rarely exists. Academic needs shift seasonally. Corporate customers sometimes scale up quickly, requiring large lots with short lead times. Having personally managed forecasts, I know we can't afford to run lean or overstocked for long. We look at real-time usage trends, and we work with research groups to schedule recurring shipments or batch-scale deliveries. That approach prevents frustrating backorders, one of the worst experiences for anybody on deadline.

    Supply chain disruptions occasionally force rapid adjustments. During global chemical shortages, we’re sometimes forced to dip into verified backup stores of core feedstocks. Because benfluorenol’s intermediate precursors can be sensitive to upstream changes, we keep extra supplies of critical solvents and maintain solid relationships with our own raw material suppliers. Whenever there’s an upstream purity challenge—odd odorous notes, unexpected color shifts—we test everything at receiving before accepting new drums into production. Teams across our site understand that surprises in the first step domino into the finished lot’s outcome. Our entire operation remains transparent—batch data remains available long after a product ships. This helps build trust when an audit lands on our doorstep or a customer hits a reproducibility snag.

    In the early years, we sometimes overlooked just how fussy customers could get about residual solvents or elemental analyses. Cost pressures pushed us to consider cutting a wash step here or a drying hour there. Experience has taught us those aren’t places to economize. The cost of a failed synthesis or a batch returned for traces of DMF dwarfs the incremental expense. Keeping purity controls tight built a reputation for less trouble downstream, and word spreads quickly among experienced synthetic chemists. I’ve fielded more than one call where a chemist relays frustrations with another supplier’s variable color grades or crystal size—even subtle changes stand out to someone conducting sensitive optical measurements or working on regulatory filings.

    Quality Assurance and Verification

    Every finished batch faces two checkpoints: the production floor’s technical team runs the first suite of tests, and our analytical lab verifies results before any product moves out the door. The process relies on people who know the pitfalls from memory. A couple of years back, our QC group invested in updated spectroscopy hardware after an ambitious project revealed missed secondary peaks. Now, HPLC and mass spec data accompany every lot. We regularly pull retained samples and recheck purity for customers tracing a synthesis or building a published protocol. For some, transparency matters as much as raw purity. We didn’t start out planning to provide raw analytical traces on request, but customer demand shaped that practice.

    If something doesn’t meet our standards, we rework or reject it—no second-rate product sources make it into finished shipments. Losses happen, but the peace of mind for researchers balances any short-term margin squeeze. Over the years, we built a knowledge base of failure modes for benfluorenol, so our team troubleshoots issues before they land in a client’s lab. Early batches of benfluorenol taught us that improper drying leads to subtle solvent inclusions, tracked by TGA measurements. Fixing it demanded process tweaks—tighter vacuum control, segmented oven schedules. Now, we rarely see the same issues twice.

    Helping Researchers Move Science Forward

    Our goal with benfluorenol is plain: deliver a compound that opens, measures, and reacts without excuses. We designed our procedures for reliability, because the frustration of resetting experiments after a material misbehaves wastes resources and tests patience. Over the years, customer feedback spurred incremental changes—additional screening against common contaminants, improvements to packaging integrity, more granular attention to atmospheric controls during final product transfer. Some research clients requested optional forms—amber glass, double-sealed foil—so we set up parallel lines to deliver both.

    Science never stands still. We watch the literature and track new developments, especially as benfluorenol finds uses far beyond traditional synthesis. Years ago, photochemical energy transfer studies sounded niche, but demand surged once more groups entered the field. Our bench chemists keep running new stability assays under simulated environmental exposures, and our technical team supports customers working at the frontier of new reactivity classes. Every exchange with a researcher offers lessons for improving the next production run. As manufacturing professionals, we accept responsibility for each gram, recognizing the role our compound plays in broader scientific discovery. Compared to abstract supply lists or faceless intermediaries, our daily goal revolves around direct support, proven reliability, and a close partnership with those advancing applied chemistry.