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Squalene

    • Product Name Squalene
    • Alias FD-SQALENE
    • Einecs 202-886-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    436144

    Chemical Name Squalene
    Molecular Formula C30H50
    Molecular Weight 410.73 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Odorless or slightly oily
    Solubility In Water Insoluble
    Solubility In Oil Soluble
    Boiling Point 285°C (545°F) at 760 mmHg
    Density 0.858 g/cm³ at 25°C
    Flash Point 210°C (410°F)
    Source Shark liver oil, olives, amaranth, and other plant sources
    Cas Number 111-02-4
    Refractive Index 1.493–1.503 at 20°C
    Use Emollient in cosmetics, vaccine adjuvant, dietary supplement
    Stability Sensitive to oxidation

    As an accredited Squalene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Squalene is packaged in a 500 mL amber glass bottle with a secure cap, labeled with safety and chemical identification details.
    Shipping Squalene should be shipped in tightly sealed containers, protected from light and air to prevent oxidation. It is generally transported as a non-hazardous liquid, but should be kept away from strong oxidizing agents. Shipping conditions should maintain a stable temperature, and containers must comply with relevant regulations for safe chemical transport.
    Storage Squalene should be stored in a tightly closed container under an inert gas, such as nitrogen, to prevent oxidation. Keep it in a cool, dry, and well-ventilated area, away from heat, light, and sources of ignition. Avoid exposure to strong oxidizing agents. Refrigeration or storage at room temperature is recommended, as extreme temperatures can cause degradation.
    Application of Squalene

    Purity 99%: Squalene Purity 99% is used in pharmaceutical formulations, where it enhances bioavailability and ensures product safety.

    Molecular Weight 410.7 g/mol: Squalene Molecular Weight 410.7 g/mol is used in vaccine adjuvant systems, where it promotes efficient antigen delivery and immune response.

    Viscosity 28 cSt: Squalene Viscosity 28 cSt is used in cosmetic emulsions, where it enables smooth texture and improved skin absorption.

    Stability Temperature 80°C: Squalene Stability Temperature 80°C is used in thermal processing of nutraceuticals, where it maintains molecular integrity during heat exposure.

    Melting Point -75°C: Squalene Melting Point -75°C is used in low-temperature encapsulation, where it prevents crystallization and preserves liquid state.

    Particle Size < 50 nm: Squalene Particle Size < 50 nm is used in nanocarrier drug delivery, where it offers high dispersion stability and controlled release.

    Dioxane Residue < 0.05%: Squalene Dioxane Residue < 0.05% is used in topical formulations, where it reduces toxicity risk and improves skin compatibility.

    Odorless Grade: Squalene Odorless Grade is used in fragrance-free skincare products, where it avoids sensory interference and maintains product neutrality.

    Oxidative Stability Index (OSI) > 25 hours: Squalene OSI > 25 hours is used in antioxidant-rich supplements, where it prolongs shelf life and prevents rancidity.

    Density 0.858 g/cm³: Squalene Density 0.858 g/cm³ is used in emulsion stabilizers, where it aids homogeneous phase distribution and consistency.

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    Certification & Compliance
    More Introduction

    Squalene: Natural Strength for Every Day

    Bringing More Than Moisture to the Table

    Squalene turns up in all kinds of places, but most folks know it best as an ingredient in skin creams and supplements. Dig a little deeper and the story gets richer. This colorless, lightweight oil once came mostly from shark liver, but plant-based squalene, especially from olives and amaranth, has become the standard for people who care about sustainability and ethics alongside performance. I've watched the conversations shift as more companies move away from animal sources, and many consumers now expect to see traceability down to the crop level.

    Take the 99% high-purity squalene commonly seen on product labels. That's the mark of olive-derived varieties pressed and processed clean, where every drop aims for the same consistency year-round. A typical squalene oil still feels feather-light, absorbs into the skin quickly, and leaves minimal residue. Unlike some heavier plant oils that can clog pores or sit on the surface, squalene works with just about any skin type without causing breakouts or shine. Its structure closely mimics what the human body makes naturally in the skin’s sebum, so it tends to “fit in” with minimal fuss.

    How Squalene Steps Up the Routine

    Using squalene brings me back to the first times I tried to fix dry patches after too many cold-weather runs. Serums failed, lots of heavier creams made things worse, but a few drops of pure squalene – no scents, no fillers – calmed the redness and took care of the tight feeling in a way nothing else managed. Over the years, I’ve recommended this one change to anyone who’s dealt with flaking, windburn, or that dull tone that never quite goes away with regular lotion.

    Many brands have caught up, adding squalene to moisturizers, sunscreens, and even shampoos. Some of the strongest arguments in favor of squalene come from dermatologists who value its stable, non-irritating nature. People with eczema or easily-upset skin often say squalene helps without leading to more redness or itching. Unlike some so-called “miracle” ingredients that promise everything and deliver little, squalene’s track record holds up in the research. It’s chemically stable; it can survive the shelf for ages without breaking down or oxidizing, and it doesn’t get sticky or sour like cheap oils do.

    What Sets Squalene Apart From the Rest

    In today’s crowded shelves, the decision rarely boils down to just picking this oil over another. Some of the more common plant oils — argan, jojoba, coconut — see plenty of marketing hype. Coconut oil, for example, finds its way into just about everything, but it can clog pores and cause breakouts in people prone to acne. Jojoba tries to mimic the feel of natural sebum too, but many notice it leaves behind a waxy finish.

    Olive-derived squalene doesn’t carry any added scents, colors, or common allergens. Its molecular structure allows it to absorb more deeply than most oils, which makes a difference for people impacted by seasonal dryness, aging, or overexposure to wind and sun. It never suffocates the skin, and it rarely aggravates existing skin problems. For those chasing a “barely-there” feel from their skincare, squalene delivers without any greasy leftovers.

    Research groups and regulatory bodies have paid close attention to purity, especially as the supplement side of the market grows. There have been discussions around safety, sustainability, and the impact of persistent heavy metals or contaminants. The most reputable squalene products now ship with lab testing results, which offer peace of mind if you’re taking a daily oral capsule instead of applying straight to your face or scalp.

    Squalene in Food and Supplements: A Broader View

    Squalene shows up far beyond the beauty aisle. Mediterranean diets provide natural squalene from olive oil, which likely plays a part in the skin quality and cardiovascular health often seen in studies on longevity. Although eating a spoonful of olive oil won’t supply as much squalene as a measured supplement, regular intake builds a case for its safety and broad benefit. Some researchers link squalene-rich diets with improved cholesterol markers and healthier cell membranes, but standardized doses and delivery methods make the supplement route more reliable for people with specific goals.

    Digestive absorption of squalene isn’t perfect. Some evidence suggests pairing it with a fatty meal helps the body take in more. This aligns with how nutrients work in whole foods, where vitamins A, D, E, and K all depend on fats for best absorption. People with strict vegan or low-oil diets might not hit similar intakes as those in the Mediterranean, so supplements sourced from amaranth or olive become more useful in these settings. With so much squalene being made using olives harvested in Southern Europe, traceability chains have tightened. You can often spot the country of cultivation on the bottle or website, thanks in part to consumer demand for clean sourcing.

    Environmental and Ethical Considerations: Shark-Free Squalene

    For decades, squalene’s main source came from shark liver — an approach both unsustainable and ethically problematic. Every batch depended on harvesting vulnerable species from the world’s oceans, most of which mature slowly and struggle to recover from overfishing. Public outcry and regulatory intervention in the past twenty years forced the biggest producers to abandon this model, and nearly all reputable cosmetic, skincare, and wellness brands now favor olive- or amaranth-derived squalene.

    Amaranth, a grain native to South America, grows in poor soils with minimal water, making it an economical and environmentally friendly crop for squalene extraction. Olive oil production produces a natural byproduct — olive pomace — that’s now one of the main sources for plant-based squalene. Compared with palm oil or soy-based derivatives, olives and amaranth offer transparency and a lower environmental footprint, provided harvesting practices maintain crop biodiversity and avoid soil depletion.

    Some companies are pushing for squalene made from fermentation, using yeast or bacteria fed with sugar. This “bioengineered” squalene holds promise for both purity and ecological impact, but costs remain high. In my experience watching the market, early-adopters tend to come from pharmaceutical and vaccine manufacturers, where the stakes for purity and reproducibility run higher than the average consumer product.

    Safety and Regulation: The Details Matter

    One thing I’ve learned from talking to pharmacists and lab scientists is to always check the label and ask for the certificate of analysis. Trace levels of contaminants may slip through in some low-cost oils, especially those made with outdated processing tools. Strict regulatory standards in the US and EU demand heavy metals and pesticides stay below set thresholds before the oil passes to the bottling stage, but products grown and processed in less-regulated regions sometimes slip through online marketplaces.

    As a direct supplement, many people turn to squalene capsules either for cardiovascular benefits or as an antioxidant. Squalene’s chemical structure allows it to “soak up” oxidative stress, protecting cells — at least, that’s the claim the science supports in animal and human studies so far. The broader relationship between oral squalene intake and overall disease prevention still requires more long-term research, but early evidence points to a positive, low-risk profile.

    In cosmetics, the safety picture looks even clearer. Hypoallergenic studies rarely show reactions, even among people with sensitive or allergy-prone skin types. Squalane — a stable, hydrogenated form of squalene — crops up in much of the same product space. Both share similar benefits, but squalene in its natural form carries a softer feel and is slightly less processed.

    Real-World Impact: What Buyers Need to Know

    Anyone searching for a quick fix for dry, flaky skin usually stumbles across squalene sooner or later. Its appeal cuts across age, skin tone, and climate. A teenager dealing with shine or redness after a day outdoors might find it soothes irritation quietly, while an older adult faces less trouble with fine lines or elasticity loss after steady use. Friends I’ve recommended squalene to almost always comment on the lack of scent and how quickly it “disappears” after application, with no oily film or heavy after-feel.

    The story broadens again for people struggling with more stubborn issues like seborrheic dermatitis or scalp flaking. There’s a small groundswell of haircare brands adding squalene to conditioners and leave-in treatments, often with the goal of fighting dryness without loading hair down. The product’s lightweight texture means it can slide neatly into most routines, whether your regimen covers just hands and face or you’re after full-body application. Squalene’s versatility turns up in post-shave balms, tattoo aftercare lotion, and cuticle oil, too. In my experience, it rarely “fights” with other ingredients, and it layers underneath or over virtually any other formula without causing trouble.

    Picking Quality Over Hype

    One risk with any widely known ingredient comes from trend-chasing. Squalene’s pop-culture moment came with the “clean beauty” wave, which led some brands to tack on buzzwords and overpromise. Not every squalene product works the same; some versions get bulked out with alcohols, parabens, dyes, or scents that cancel out the benefits. I tell people to check ingredient lists and look for transparency statements from suppliers — the best players explain their supply chain, offer lab test results, and disclose extraction methods. Price sometimes signals purity, but plenty of affordable, honest choices exist.

    Conversations about squalene draw attention to the lack of federal regulation in the US cosmetics market. No single government body checks every moisturizer making “squalane-rich” claims for fraud or accuracy. The strongest safeguards come from brands willing to go beyond the minimum, seeking out third-party certification or going public with batch data. As with olive oil, purity falls along a spectrum — unfiltered, minimally processed oils maintain more of the original nutrients but might spoil faster, while ultra-processed, stabilized squalene holds up on any shelf but loses certain plant-based polyphenols.

    Supporting Sensitive Skin and Special Populations

    People with eczema, rosacea, and certain allergic conditions often struggle to find reliable, gentle products. Squalene’s legacy in dermatology traces back decades, long before the beauty industry got involved. Its record in reducing redness and irritation stands up to scrutiny. Unlike mineral oil or petrolatum, which lock moisture in but don’t nourish, squalene doesn’t leave a heavy, “trapped” feeling. In my household, even the youngest and oldest members tolerate squalene without rashes or flares, which can’t be said for a long list of drugstore creams.

    Pregnant women and new parents often ask me about safe, scent-free moisturizing for stretch marks or dry baby skin. Squalene stands out as a top pick, thanks to its natural origin and history of safe use. In post-surgical or post-laser recovery, doctors sometimes recommend squalene or its hydrogenated cousin squalane to restore skin flexibility and support healing. That being said, a patch test always makes sense with any new topical product, especially for people with a known record of reactivity.

    Balancing Technology and Tradition

    What draws me to squalene, and what I see in the habits of longtime users, is the rare blend of science-backed benefit and simple, traditional use. All across the Mediterranean, oils pressed from olives find a place not just in meals but in home remedies. My own Italian relatives dabbed olive oil on sunburns and mixed it with other herbs for deep winter dryness. Modern squalene products build on this tradition, isolating one of the olive’s key moisturizing molecules but stripping out the extra compounds that cause heaviness or spoilage.

    Researchers and companies tackle the challenge from both ends: improving purity through better extraction, and teaching consumers to spot marketing trickery. Every new season brings a few more squalene-infused products at the pharmacy, but the classics — pure oil, simple serums, and capsules with minimal fillers — keep the core audience loyal. People want to see honesty and results, not just another trendy bottle with promises no one can verify.

    Not Just for Humans: Veterinary and Medical Uses

    The virtues of squalene stretch into less-visible corners of healthcare. Veterinary dermatologists sometimes recommend squalene-based ointments for pets with chronic dryness or skin trauma. Because squalene works as an emollient without smothering or causing allergic reactions, it’s made its way into specialty ointments for dogs, cats, and horses under the care of a vet.

    In medicine, squalene’s most famous turn comes as an adjuvant in vaccines, helping to deliver antigens efficiently without creating side effects or allergies found in older formulas. Some flu and COVID-19 vaccines use squalene for this purpose, though the quantities are minuscule compared to cosmetic use. The shift to plant-based sources in this context carries weight; patients and advocates alike want to avoid triggering new environmental problems while improving public health outcomes.

    Direct Experience in Day-to-Day Life

    Personal care routines grow more complicated with each passing year. Sorting through countless bottles, tubes, and claims, people deserve real answers to real-life problems. In my experience moving through icy winters and humid summers alike, squalene provides a consistency that no “miracle water” or spa mask has matched. The product genuinely becomes part of your skin’s toolkit, not a decoration for the medicine cabinet.

    Friends who once spent fortunes chasing after designer creams often shift gears, paring back to a few straightforward ingredients. Squalene makes the shortlist for many. Even those in their teens — learning about ingredient lists for the first time — see visible improvement, not just for dryness but in softening scars and calming breakouts. Men use it as a beard oil or aftershave; children tolerate it without protest; older adults use it to bounce back from harsh soaps and weather.

    Some of the best feedback comes from people in the medical field. Nurses working with frequent hand washing tell me squalene outlasts expensive lotions, and outdoor workers with sun- or wind-chapped skin often keep a vial in the truck or at home. The rare combination of purity, absorption, and lack of fragrance seems to make the biggest difference. There’s no learning curve, no complicated regime; you just apply a drop and move on with your day.

    Squalene’s Broader Social Value

    The switch from shark-derived squalene to renewable plant sources marks a rare win — a product that makes life better without making the world worse. Communities that once supplied shark oil now rely on more sustainable crops, opening up new markets for farmers instead of fishermen. In regions with abundant olive groves, value increases for every part of the harvest, not just the fruit for eating or pressing into bottled oil. This kind of closed-loop economy means less waste and better income for people at every step in the supply line.

    Education drives the transition. With more people aware of sourcing and sustainability, there’s less opportunity for mislabeling or dilution. Online forums, parent groups, and health professionals play critical roles in pushing brands toward greater honesty. Those who buy squalene in bulk for small-scale production also support cooperatives undertaking ethical, local growing. The idea that every purchase supports an entire ecosystem — farmers, processors, retailers — makes daily skincare feel less disposable and more connected.

    Choosing the Right Squalene Product

    Experience and evidence both suggest that pure, cold-pressed squalene, kept free from fillers, delivers the best both in terms of results and peace of mind. Look for clear sourcing from olives or amaranth, direct lab validation for purity, and confirmation that products meet safety expectations in your region. Whether added to DIY lotions, used as a finishing touch after cleansing, or taken as a supplement in capsule form, the key comes down to finding honesty on the label and feedback from real-world users.

    With good information and thoughtful shopping, squalene lets people tap into an old-world solution modernized for new needs. Alongside new extraction methods and rising demand for plant-based ingredients, squalene continues to gain relevance far beyond its old image as just another beauty oil. It answers daily needs for moisture, barrier repair, and comfort with fewer risks and more benefits than most alternatives. Making that choice — for yourself, for your family, for your community — hits at the heart of why real ingredients, proven by time and science, matter.