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HS Code |
576441 |
| Chemical Name | Oleanolic Acid |
| Cas Number | 508-02-1 |
| Molecular Formula | C30H48O3 |
| Molecular Weight | 456.70 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 310-315°C |
| Solubility | Insoluble in water, soluble in ethanol and chloroform |
| Purity | Typically ≥98% |
| Source | Naturally occurs in various plants such as olive, garlic, and apple peels |
| Chemical Structure | Pentacyclic triterpenoid |
| Boiling Point | Decomposes before boiling |
| Storage Conditions | Store in a cool, dry place away from light |
| Synonyms | Oleana-12-en-28-oic acid |
As an accredited Oleanolic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Oleanolic Acid, 25g, packaged in a sealed amber glass bottle with a screw cap and clear hazard labeling for laboratory use. |
| Shipping | Oleanolic Acid is shipped in tightly sealed containers, protected from light, moisture, and heat. Packaging complies with chemical safety standards, ensuring secure transport. During shipment, labels indicate chemical identity and hazard warnings. Temperature control and handling precautions are followed to maintain product stability and prevent contamination or degradation throughout transit. |
| Storage | Oleanolic Acid should be stored in a tightly sealed container, protected from light and moisture, at room temperature (15–25°C). It should be kept away from incompatible substances, such as strong oxidizing agents. Ensure the storage area is dry and well-ventilated. Properly labeling and maintaining the chemical in original packaging helps preserve its stability and prevents contamination. |
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Purity 98%: Oleanolic Acid with 98% purity is used in pharmaceutical formulations, where it enhances anti-inflammatory efficacy. Particle Size <10 µm: Oleanolic Acid with a particle size below 10 µm is used in topical creams, where it improves skin absorption rates. Melting Point 310°C: Oleanolic Acid with a melting point of 310°C is used in solid dosage manufacturing, where it provides thermal processing stability. Molecular Weight 456.7 g/mol: Oleanolic Acid of 456.7 g/mol molecular weight is used in nutraceutical supplements, where it ensures precise dosing accuracy. Stability Temperature up to 120°C: Oleanolic Acid stable up to 120°C is used in cosmetic emulsions, where it maintains formulation integrity during storage. Water Insolubility: Oleanolic Acid’s insolubility in water is utilized in sustained-release drug delivery, where it allows controlled bioactive release. HPLC Assay ≥99%: Oleanolic Acid with HPLC assay not less than 99% is used in research studies, where it guarantees reliable bioactivity measurements. Micronized Grade: Oleanolic Acid in micronized grade is used in transdermal patches, where it achieves enhanced therapeutic penetration. |
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Oleanolic acid often lives in the background. While most people walk past olive trees or sample traditional herbs without thinking twice, their bodies might already have encountered this natural triterpenoid. Extracted mainly from olive leaves, but also found in dozens of familiar plants like Chinese honeysuckle, oleanolic acid has carried its quiet weight in both folk and modern research circles. Chemists usually identify it by formula C30H48O3, and researchers looking for a dependable anti-inflammatory, antioxidant, or liver support compound keep turning to this ingredient for a reason.
Lab techs often pull oleanolic acid off the shelf in a pale white or cream crystalline powder, favoring purity grades from 80% to 98%, depending on the task. Pharmaceuticals call for a high-purity version, usually 98% or higher, which comes with a specific melting point between 285 and 288°C. Lower-purity (80%-95%) grades might go into cosmetics or functional foods, where minor plant residues aren’t an issue. HPLC testing measures just how “clean” a sample really is. Moisture content stays under 2%. Bulk density, particle size, and solvent residues all matter based on target uses, but most focus sits firmly on purity and consistent sourcing.
Though the average person rarely asks about oleanolic acid, this molecule often finds its way into routine wellness. Anyone who’s used herbal liver supplements, certain anti-inflammatory extracts, or skin care formulas for redness relief has engaged with it. In the world of drug development, oleanolic acid gets a serious look for its documented liver-protective qualities, something the Chinese Pharmacopoeia and other pharmacopeial guides also highlight. Doctors and traditional healers in East Asia have made use of this plant compound for centuries, blending it into remedies that balance liver detoxification, protect cells from oxidative stress, and support the body’s normal immune functions. More recently, scientists have examined its cholesterol-lowering and blood sugar balancing potential.
Research points to its role as a gentle antioxidant that scavenges free radicals and reduces inflammation. Lab studies often cite its hepatoprotective action—helping shield the liver from chemical or alcoholic stress. Some academic papers detail its effect on key enzyme systems, including phases of drug metabolism, and link oleanolic acid to possible antidiabetic, anticancer, and cardiovascular benefits. Formulators in the supplement industry seem drawn to this “Swiss Army knife” of bioactives, not for its flashiness, but for the solid results shown in both preclinical and some early clinical work.
Standing in the shoes of a product developer or an everyday consumer, it’s smart to ask why oleanolic acid holds a certain place on the ingredient list. Look at ursolic acid, for instance—structurally similar, yet with slightly different plant sources and biological strengths. Both molecules belong to the pentacyclic triterpenoid family, but while ursolic acid sometimes takes the lead in anti-obesity or muscle-building research, oleanolic acid’s gentle hand in liver care and inflammation suit other areas.
Some customers hop on the bandwagon for widely marketed antioxidants—curcumin, resveratrol, or quercetin, to name a few. Oleanolic acid brings its own strengths to the table, and the supporting papers reveal fewer issues with absorption or rapid breakdown in the body. One reason: its lipophilic nature helps it integrate in cell membranes and exert prolonged stay in tissues like the liver. Many antioxidants break down quickly or never get absorbed at all, but oleanolic acid’s real-world use in herbal medicine and science both show genuine potential. That authenticity, rooted in tradition and proven in laboratories, sets it apart from flashier newcomers with less staying power.
From experience, sourcing ingredients can feel like walking a minefield. Quality varies widely, and not all oleanolic acid is created equal. Plant origin influences trace residue and environmental contaminants. Olives grown in Mediterranean soils tend to show a cleaner profile than those harvested from heavily sprayed orchards elsewhere. Extraction matters, too—supercritical CO2 processes, while costly, avoid nasty solvents; old-school ethanol extractions might leave behind residues but work well for traditional products. Reputable suppliers publish certificates of analysis and batch records, letting buyers trace samples right back to their harvest. These steps aren’t paperwork—they’re basic measures that help protect both end users and the trust in natural products.
I’ve watched savvy companies skip cheap, mass-produced imports, focusing instead on traceability and independent third-party testing. End users might never see this due diligence, but it makes a world of difference when recall notices or regulatory reviews land in the inbox. In the age of social media and watchdog groups, even a minor misstep becomes a public relations headache. Honest labeling, real batch control, and transparent records remain the backbone of quality oleanolic acid—whether it’s headed for encapsulation, tinctures, or topical gels.
On paper, oleanolic acid could look dry or “generic,” especially to those drawn to exotic plant discoveries. Experience tells a different story. There’s simple wisdom in relying on a molecule that works, and real evidence supports its consistent use across the globe. The basics—liver care, inflammation support, robust cell health—never lose relevance. When over a hundred peer-reviewed studies discuss one natural compound’s role in managing oxidative stress, metabolic disease, or even as an adjunct to modern chemotherapy, health professionals and laypeople both benefit.
Consumers deserve more than hype; they need clarity and proof from both science and tradition. Oleanolic acid delivers here. Several extractors now provide certifications covering everything from non-GMO status, low heavy metal content, and lasting shelf stability, usually for up to three years in airtight, cool conditions. There’s not much glamour in a white powder, but those tightly controlled specs don’t just serve paperwork—they guard real human safety. The fact is, modern wellness leans on established facts, not fads. Oleanolic acid fits that bill better than most.
In my own experience, I’ve seen oleanolic acid both as a solid supplement and as an ingredient inside skincare products. Capsule manufacturers usually blend it at doses measured in tens of milligrams, betting on its synergy with other liver botanicals. The compound gets praised for being gentle on digestion and rarely triggers side effects at standard doses. People who deal with skin irritation or want to calm visible aging sometimes seek out topical treatments that use oleanolic acid for its calming and anti-inflammatory effects. Creams or gels blend it at low concentrations, pairing it with vitamins or natural emollients.
One notable difference shows up in how the molecule interacts with the body: oleanolic acid binds selectively to liver cell surfaces and helps regulate enzymes linked to detoxification, yet it rarely suppresses normal immune function. That appeals to medical practitioners wary of blunt, non-selective therapies. As part of a functional food recipe or powder mix, oleanolic acid seems to keep its stability during processing and storage. Whether it’s a supplement or a cream, the track record for low irritation stands out compared to more aggressive natural extracts.
At street level, few people will say, “I take oleanolic acid every morning.” But populations in the Mediterranean, East Asia, or regions with rich traditions in herbal teas and tinctures have been quietly getting daily doses for generations. Epidemiological studies point toward lower rates of metabolic and liver disease in groups consuming olive and plant-rich diets that naturally contain this molecule. Modern supplements try to isolate and boost those benefits, making them accessible beyond traditional geographies.
Liver health concerns now touch all corners of the globe, as rates of fatty liver disease climb—linked to processed food, pollutants, and sedentary lifestyles. Oleanolic acid doesn’t act as a miracle, but as a piece in the puzzle for sustainable health solutions. It might not win headlines, but its part in the larger tapestry of dietary intervention, lifestyle change, and traditional remedies wins quiet respect from those who keep track of the data.
Consumer protection often feels invisible until something goes wrong. Oleanolic acid’s long history of use sits on a backbone of solid phyto-safety data. Years in the supplement world have taught me that even safe ingredients can run into trouble with dosing errors or contamination. Large doses, well above normal supplement levels, have potential to interfere with how drugs metabolize in the body, especially those processed by the liver. Medical professionals keep a close watch for unwanted interactions, particularly with prescription medicines. A well-prepared product will supply real dosing guidelines, not broad assumptions, to avoid accidentally tipping the balance.
Reputable suppliers subject bulk oleanolic acid to allergen, pesticide, and heavy metal screening. Clean samples, free from harmful residues, don’t grab headlines—but they quietly protect families. That’s where a direct relationship with a source pays off. Those who’ve spent time in contract manufacturing or product development know that a trusted supplier, with full traceability and transparent testing, nearly always produces better outcomes than anonymous online sources.
People trust simple solutions—drink more water, eat more plants, move more—but nuanced answers drive lasting health. Oleanolic acid fits in this balance. While the knowledge base for this compound continues to grow, better education on its use can help demystify it for the regular consumer. Integrative health practitioners and product developers have a responsibility to offer clear explanations, citing proven research and traditional background, rather than hype or marketing copycatting.
Ideally, future efforts will focus on head-to-head studies comparing oleanolic acid with commonly used liver protectants or antioxidants. This would firm up its status in the supplement aisle and provide doctors with confidence when recommending plant-based options. Wider clinical trials, conducted across different demographic groups, could also unearth new therapeutic windows or underline safety margins. At the same time, more transparent supply chain management and third-party certification remain essential in a world where public mistrust in plant extracts can spiral after a single bad batch.
Standing in the nutritional supplement aisle or browsing online, buyers now see a dizzying range of plant-based products, each promising miraculous results. Oleanolic acid might not top the list of brand names, but it’s worth considering how this understated molecule has weathered decades of scrutiny. Most products featuring oleanolic acid won’t come with wild weight-loss or overnight cure claims. What shows up more often are modest, data-supported health promises—better liver resilience, mild support for cholesterol control, and gentle action on inflammation.
For new users, the story isn’t about chasing the latest trend, but about adopting a plant molecule that sits at the intersection of food, tradition, and research. It offers something rare: a documented record stretching from traditional teas in Asia to pharmacological studies in Western labs. Unlike some “distilled” supplements, oleanolic acid retains a meaningful link to its original plant sources, which provides a fuller picture of health benefits.
Trust builds over time—through repeated good results, clear labels, and honest reporting. Oleanolic acid offers an understated but important link in the chain of supportive wellness ingredients. Science and real-world results both reinforce its value, cutting through the noise of heavily marketed fads. People looking for liver care, gentle anti-inflammatory benefits, or a quiet boost in antioxidant intake can count on a molecule that’s earned its place through generations of use and transparent evidence.
The demands for clean, responsibly sourced, and clinically measured wellness products only continue to climb. Oleanolic acid, when properly produced and honestly marketed, stands ready to meet that need without making noise. Its modest profile shouldn’t fool buyers or professionals—this quiet plant molecule continues to shape both what goes on the shelf and what stays in common health routines, driven by science and sound tradition alike.
Looking at where oleanolic acid lands in the evolving supplement world, two paths seem clear. Researchers will keep testing new uses, building on a firm foundation of safety and historic benefit. At the same time, suppliers and brands must double down on supply chain responsibility—protecting natural environments, honoring fair-trade principles, and defending against adulteration. Only through careful stewardship can oleanolic acid move from a specialty botanical to a more mainstream tool for health.
In the end, people respond to truth and earn results. Oleanolic acid’s quiet story proves that a well-chosen natural molecule backed by tradition and proven in labs can stick around, no matter what the next health trend claims to offer.