Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Metapirazone

    • Product Name Metapirazone
    • Alias Mizol
    • Einecs 253-562-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    671419

    chemical_name Metapyrizone
    other_names Pyrazone, 2-methyl-3-pyridazinone
    cas_number 2440-60-6
    molecular_formula C8H9N3O
    molecular_weight 163.18 g/mol
    appearance White to off-white crystalline solid
    solubility Slightly soluble in water
    usage Herbicide
    mode_of_action Inhibits photosynthesis at photosystem II
    toxicity_class Low to moderate toxicity
    melting_point 156-158°C
    application Selective weed control in crops
    storage_conditions Store in a cool, dry, well-ventilated place
    stability Stable under normal conditions
    structure Pyrazone derivative

    As an accredited Metapirazone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Metapirazone is packaged in a sealed 25 kg fiber drum, featuring a secure lid and labeled hazard information for safe transport.
    Shipping Metapirazone should be shipped in tightly sealed containers, protected from moisture and light. Transport under cool, dry conditions in compliance with local regulations for hazardous chemicals. Ensure proper labeling and documentation. Avoid contact with incompatible materials, and handle with appropriate personal protective equipment to safeguard against accidental exposure during transit.
    Storage Metapirazone should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and direct sunlight. Keep the container tightly closed and clearly labeled. Store separately from incompatible materials such as strong oxidizers and acids. Avoid exposure to moisture. Ensure storage facilities are equipped with suitable spill containment and that access is limited to authorized personnel.
    Application of Metapirazone

    Applications of Metapirazone in Industrial Manufacturing

    As an established producer of Metapirazone with longstanding engagement in the global agrochemical and chemical synthesis sectors, we supply material that directly meets the stringent quality and safety criteria required by modern downstream industries. This section outlines key application scenarios where our product serves as a critical input, specifying real-world formulation practices, sector-specific regulations, integration steps, and resultant finished goods.

    1. Herbicide Formulation for Cereal Crop Protection

    Commercial crop protection companies rely on Metapirazone as an active herbicidal ingredient for selective weed control in cereals such as wheat, barley, and rye. Our material is typically formulated with surfactants, adjuvants, and other co-active substances to enhance leaf uptake and target specific broadleaf weeds. The usage protocol depends on local regulatory approvals and crop specifications, requiring exact addition during the agrochemical suspension concentrate or wettable powder production phases. Rigorous traceability and batch control accompany all steps through QC laboratories before downstream packaging and labeling of the final end-product for distribution to grower networks.

    Industry compliance standards

    • EPA 40 CFR Part 180 – Tolerance regulations for herbicide residue in U.S. cereals
    • Regulation (EC) No 1107/2009 – EU authorization of plant protection products
    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • GB 2763-2021 – China’s Maximum Residue Limits for pesticides in food

    Typical usage ratio

    • 5%–25% w/w depending on target crop, formulation type (SC, WP, EC), and region-specific regulatory limits
    • Adjusted according to weed spectrum, resistance management protocols, and climatic conditions

    Downstream process integration

    • Direct addition to the formulation kettle during batch agrochemical blending
    • Incorporation into micronization or suspension-milling systems before in-process quality sample testing
    • Subjected to HPLC or GC analysis and wet sieve testing as part of QC workflow

    Final product types

    • Suspension concentrates (SC)
    • Wettable powders (WP)
    • Emulsifiable concentrates (EC)
    • Granular herbicide formulations

    2. Intermediate for Industrial Synthesis of Pyrazone-Based Agrochemicals

    Major active ingredient manufacturers utilize Metapirazone as an intermediate step in synthesizing more complex pyrazone-based agrochemical actives. Custom synthesis routes introduce our raw material through pyridinone or triketone extension reactions under controlled temperature and agitation, with real-time monitoring of reaction conversion. Adherence to global GMP and hazardous substance management standards is essential for batch release and transition to scale-up. This scenario demands detailed MSDS documentation, multi-step purification, and robust in-process sampling to support downstream diversification into branded actives destined for international agrochemical portfolios.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • REACH Regulation (EC) No 1907/2006 for supply chain traceability
    • Globally Harmonized System (GHS)/CLP classification for hazardous chemical intermediates

    Typical usage ratio

    • 0.8–1.1 molar equivalents as a limiting or excess reagent, varying by downstream target molecule
    • Stoichiometric adjustments made for desired functionalization and intermediate conversion yield

    Downstream process integration

    • Charged at the reaction start during multi-step batch or continuous flow synthesis
    • Monitored via spectrophotometric/UV-Vis analysis to optimize residence time
    • Integrated with solvent recovery and crystallization purification prior to final QA/QC checks

    Final product types

    • Active ingredient intermediates for branded crop protection products
    • Custom pyrazone derivatives for downstream formulation partners
    • Building blocks for fungicide and insecticide R&D applications

    3. Active Constituent in Selective Industrial Turf and Lawn Care Solutions

    Turf management solution companies leverage our raw material in the development of pre-emergent and early post-emergent herbicides for golf courses, sports fields, and amenity grasslands. Stringent compliance with local green space and environmental safety standards is mandatory, and formulations are adjusted for seasonal application cycles, sod type, and municipal approval protocols. The material is introduced during mixing and granulation steps, followed by precision blending and drying processes to ensure even dispersal within controlled-release carrier systems before heading to commercial packaging lines.

    Industry compliance standards

    • EIFAC guidelines for sustainable use in recreational turf management (Europe)
    • U.S. FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act) compliance for turf chemicals
    • ISO 14001:2015 Environmental Management System

    Typical usage ratio

    • 3%–15% w/w, with adjustment for carrier type (granule, liquid concentrate) and field trial data on turf varieties

    Downstream process integration

    • Batch-wise addition to rotary granulators and pan coaters for granular formulations
    • Blending with controlled-release polymers or absorbent carriers during liquid concentrate production
    • Post-production field efficacy and residue testing to confirm regulatory compliance

    Final product types

    • Granular turf herbicides for commercial landscapers
    • Suspension concentrates for professional lawn care service providers
    • Combination turf and weed control granules for public sector groundkeepers

    4. Non-Food Crop Protection in Industrial Forestry and Plantation Maintenance

    Large-scale silviculture and industrial forestry operations apply Metapirazone-based formulations to manage invasive weed pressure and protect young non-food trees during early establishment. These operations harmonize product usage with national forestry management regulations, ecological risk assessments, and certified sustainable forestry initiatives. Precise addition during the formulation of aqueous or oil-based sprays is required, often at left-field mixing stations with scheduled rotation and inventory control. Traceability and alignment with sustainability reporting standards are mandatory for all sold lots to support downstream chain-of-custody certification and audit programs.

    Industry compliance standards

    • Forest Stewardship Council (FSC) chemical use policy for forest management
    • PEFC Chain of Custody (CoC) requirements
    • Local Environmental Protection Authority (EPA) usage permits

    Typical usage ratio

    • 2%–10% w/w, differentiated by local weed grass spectrum and climate-related application intervals

    Downstream process integration

    • On-site dissolution at forestry chemical application facilities
    • Tank-mix preparation and in-line filtration to prevent nozzle blockage during aerial or terrestrial spraying
    • Routine batch tracking for end-user reporting and regulatory audit compliance

    Final product types

    • Forester-applied herbicide liquids for plantation weed management
    • Industrial forestry weed control concentrates
    • Pre-mixed agrochemical packages for state or commercial tree nurseries

    5. Research Reference Substance for Analytical Laboratories Specializing in Agrochemical Validation

    Accredited laboratories engaged in residue analysis and stability testing employ high-purity Metapirazone as a certified reference standard (CRS) for method validation, regulatory submission, and trace-level quantification in crop matrices. Laboratories require material that meets ISO/IEC 17025 traceability, custom-packaged for LC-MS/MS, GC-MS, or HPLC methods as stipulated by international scheme accreditation. Batch re-certification, homogeneity testing, and documentation traceability remain critical for standard supply to ensure the accuracy of downstream analytical results supporting new product registration and post-market surveillance.

    Industry compliance standards

    • ISO/IEC 17025:2017 Laboratory Competence Accreditation
    • OECD Principles of Good Laboratory Practice (GLP)
    • European Pharmacopoeia Reference Standards (when relevant for analytical calibration)

    Typical usage ratio

    • 0.1–5 ppm as solution standard, depending on detection technique and matrix complexity
    • Supplied according to customer’s method validation plan

    Downstream process integration

    • Direct use in spiking solutions for instrument calibration and quality range verification
    • Preparation of standard curves in residue, migration, or environmental monitoring assays
    • Inter-laboratory comparison studies and proficiency testing routines

    Final product types

    • Certified secondary reference standards for method calibration
    • Commercial test kits for agrochemical residue screening
    • Contract laboratory analytical service packages
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    Certification & Compliance
    More Introduction

    Metapirazone: Building Value from the Factory Floor

    What Metapirazone Means to Us

    Metapirazone production looks simple from the outside. In reality, what happens behind the scenes reflects years spent refining each process step on the shop floor, learning from daily runs, and listening closely to the industries we supply. For those of us who manufacture specialty herbicides, consistent quality and practical results matter more than promotional buzzwords. It's not just another option on the product list; it's a direct response to growers and formulators needing real improvements in selectivity, cost management, and application results.

    Specifications and Practical Choices

    In our own workshop, Metapirazone comes out as a fine crystalline powder, usually with an active ingredient content above 95%. Meeting that bar doesn’t happen by accident. Process control teams measure every batch’s melting point and purity, not just for the paperwork but for how it affects suspension concentration, solubility, and field application. Our standard output suits large-volume suspensions but we can make dust-free granular forms if a client process calls for it. Particle size comes out consistent, with narrow distribution, from years of adjusting sieve selection and milling parameters. These details aren’t about ticking boxes; they have shown in practice to make less dust in bulk handling, fewer nozzle blockages during spraying, and a more predictable loading dose for mixing tanks.

    Where Growers Use Metapirazone and How We Keep It Reliable

    Metapirazone isn’t new to pre-emergence weed control in sugar beet and some legume crops, yet the demand for reliable herbicide action always nudges us to keep tightening every step from synthesis to packing. The product’s selectivity comes from a pyridazinone backbone, letting growers manage most broadleaf weeds—especially those resistant to older chemistry—without hammering yield. This selective property depends on maintaining impurities below trace levels, not just for regulatory limits but to guard against phytotoxicity in sensitive seedlings. Many customers split their orders by crop cycle and climate. We work to shorten turnarounds because holding inventory is costly when weather windows narrow. Our filling line shifts quickly from bulk sacks for large-scale farms to smaller bags for specialized seedling producers, thanks to modular packing stations designed after years of feedback.

    What Sets Metapirazone Apart from Older and Newer Herbicides

    We’re often asked what separates our Metapirazone from alternatives like metribuzin or older triazinone herbicides. In the field, we see growers get better control of problem weeds—like Chenopodium and Amaranthus—especially where resistance pressure has mounted over decades using the same chemistries. Metapirazone operates through a distinct inhibition pathway, showing less risk for selection of cross-resistant weeds. Formulators appreciate that it blends well with other pre- or post-emergence partners, due to its stable pH window and low risk for chemical antagonism. The water-dispersible concentrate remains stable over a longer shelf life than metribuzin, based on our monitored warehouse results. This stability matters in export since ambient storage in transit rarely matches lab conditions.

    Some products arrive with more aggressive toxicity profiles to non-target crops or demand higher buffer zones. Metapirazone has allowed us to deliver a tool that steers clear of those disadvantages—as confirmed by repeated row trials in both neutral and alkaline soils in regional test plots across multiple seasons. Its breakdown products don’t persist, keeping residues in rotation crops below threshold. Our analytics lab keeps watch on each cycle for metabolites; this data often reassures cautious end-users in both food and feed applications.

    Addressing Crop Resistance and Environmental Concerns

    Every herbicide faces the challenge of evolving weed populations. We maintain a library of resistance screening results, run on field samples from several continents each year. Metapirazone's mode of action remains effective against most resistant biotypes under current use patterns, yet we share practical instructions with buyers on application rotation, dose timing, and IPM integration. Trying to outpace weed evolution requires more than a new molecule; it requires long-term partnership between growers and manufacturers. That's one reason we’re open to conducting field demos under real local pressures, not controlled trial plots that hide trouble spots. Our field techs collect samples from both treated and buffer strips, and decisions go right back into our process adjustment meetings.

    Environmentally, we focus on keeping the technical-grade active as clean as possible. Synthesis technicians have reduced solvent residues by modifying purification methods, based on effluent and residual monitoring. The end result is lower downstream treatment and a lower burden for applicators required to document their environmental impact. We avoided using persistent carriers in granular grades, so after application the product doesn’t linger in runoff or leachate.

    Learning from User Realities

    Growers and distributors do not work in controlled environments. Neither do we. Product feedback reaches us from large row-crop operators, specialized vegetable farmers, and third-party sprayer contractors. Clumping in transport, caking in humid storage, slow dispersal in cold fill tanks—these problems don’t appear in standard test reports, but we see them often enough in returns or complaints. To address these, we added real-time QA sampling at our packing lines and randomized batch distribution in domestic delivery, so product sent to one region never sits longest on the shelf. Our team worked with applicators who had trouble re-suspending old stock after winter; by modifying the micro-granule coating and adjusting the blend ratios of our dispersing agents, we saw lower clumping and less wasted product.

    Cost isn’t just about per-kilo pricing. We spend time in procurement meetings dissecting where packaging adds logistical friction or where unnecessary intermediaries add costs for end users. In the past, some customers preferred fancy transport drums. Experience has shown that standard fiber drums suffice for domestic runs, cutting total supply chain expense. Biological safety comes from steady process improvements, not expensive wrapping.

    Compliance, Documentation, and Traceability

    Regulatory compliance in herbicides grows stricter year by year. We meet not only local rules for purity and packaging but aim to stay above threshold requirements, anticipating future changes. Our analytical records run batch-by-batch, logged from raw material intake through every stage of the batch reactor. We retain samples for retrospection, not just for paper compliance, but because tracing back through a failed batch detection gave us our best cost-saving evidence two years ago, when a solvent lot issue threatened several shipments. Documentation comes as digital files to each buyer, timed with delivery, because nobody wants to wait for delayed certificates.

    Trust comes from traceability, not just claims of quality. We invite auditors for unannounced visits and allow end customers to check lot codes back to our manufacturing steps. Tracking batch deviations to process logs gives not just quality assurance, but technical data our partners can use in their own downstream documentation.

    Supporting Sustainability through Manufacturing Choices

    Raw material sourcing shapes sustainability outcomes more than often supposed. By sourcing core reagents regionally when feasible, we limit transportation costs and lower emissions. Our solvent recovery closed loop meant we cut down virgin solvent use by about a third over three growing seasons. Colleagues in waste treatment track effluent composition so every step in synthesis gets reviewed yearly for greener alternatives. These aren’t just checkboxes for reports—they help us remain competitive as regulations and retailer requirements change.

    Energy use tells its own story. Investment in heat exchangers for crystallization and smart controls on our reactors brought measurable drops in fuel consumption. These savings allowed us to keep pricing steadier through last year’s jump in natural gas costs. Resource management ties directly to product cost, and long-term buyers see the result in continuity of supply as much as in any marketing pitch.

    Technical Support Beyond the Sale

    Selling Metapirazone doesn’t end with a transaction. Each shipment includes direct-line support to our technical staff—those same people who ran the pilot plant—so user queries get answered without wading through generic call centers. Often, the best questions come from buyers facing challenging tank-mix scenarios or drift restrictions due to shifting conditions. Our team keeps in touch after harvest, reviewing residual reports and real performance data.

    Practical support also means field days, on-site support during calibration sessions, and refreshers on application timing. We offer these because the best lessons come across the field rows, not from a desk. For new markets, our agronomy partners consult directly on typical regional weeds and the best matching mixtures.

    Research and Forward Thinking

    Metapirazone may have become a standard in sugar beet cropping systems, but research never stands still. Our in-house R&D division tests new co-formulation partners, looking for both chemical stability and cost efficiency in new delivery systems. The rise of unmanned aerial spraying and micro-dosing requires smaller, more tailored packaging and guarantees of consistent micronization, which we work on with pilot lots for innovative growers. We design these trials around the specific environmental conditions and pest profiles submitted by our end-users.

    We share lessons learned through professional networks and technical bulletins, providing honest analysis of outcomes, even when product performance diverges from expectations. Collaboration with independent agronomists and university partners remains part of our approach—practical results come from an open exchange, not locked-down protocols.

    Meeting the Challenge of Demand Fluctuation

    Seasonal demand for Metapirazone can swing sharply on news of new resistance outbreaks or export regulation changes. Keeping up requires production flexibility, proactive raw material sourcing, and logistics partners willing to adapt on short notice. We keep a buffer stock for regular buyers without holding piles of overstock that risk expiry. Batch scheduling software allows us to sync output with tractor days in key regions, so shipments arrive for mixing tank load, not months ahead or late after the season turns.

    Surplus never sits neglected. We coordinate with local crop service providers who redistribute excess to smaller-scale operators, minimizing waste and turning unsold product into lasting business relationships. If a season’s weather upends original forecasts, we adjust next year’s projections based on open meetings with buyers, not just time-series algorithms. This two-way feedback helps our forecasting accuracy and reduces piles of returned goods.

    Why We Keep Looking for Better

    Metapirazone’s journey, from batch reactor to mixing tank, creates value only if it solves persistent problems in real fields. As chemical manufacturers, the responsibility falls to us to avoid complacency and listen to field realities—regardless of what the market currently rewards. If a new contaminant emerges, or a logistical bottleneck appears, our teams gather quickly to study root causes and test improvements, whether that’s a new filtration mesh or another tweak in the carrier blend.

    Our direct engagement with the application end shapes both today’s Metapirazone and tomorrow’s product lines. Each season, we target continuous process improvement—not just maintaining output but raising the bar. The best proof comes from repeat orders and the robust yields shown by customers who have grown with us. By blending practical feedback with persistent technical effort, we continue to deliver a herbicide that meets the needs of today’s crop protection—while preparing for tomorrow’s challenges.