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Chalothane

    • Product Name Chalothane
    • Alias halothane
    • Einecs 200-909-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    474901

    chemical_name Chalothane
    other_names Halothane
    molecular_formula C2HBrClF3
    molar_mass 197.38 g/mol
    appearance Colorless, volatile liquid
    odor Sweet
    boiling_point 50.2 °C
    melting_point -41 °C
    density 1.872 g/cm³
    vapor_pressure 243 mmHg (at 20 °C)
    solubility_in_water Approximately 0.3 g/100 ml
    refractive_index 1.503 (20°C)
    stability Stable under recommended storage conditions

    As an accredited Chalothane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Chalothane is packaged in a sealed, amber glass bottle containing 500 mL, with clear hazard labeling and a tamper-evident cap.
    Shipping Chalothane should be shipped in tightly sealed, clearly labeled containers, compatible with the chemical's properties. It must be transported according to relevant regulations for hazardous materials, protected from heat, moisture, and direct sunlight. Ensure proper documentation accompanies each shipment, and handle with care to prevent leaks, spills, or accidental exposure.
    Storage **Chalothane** (Halothane) should be stored in tightly closed, amber-colored bottles to protect it from light. Keep it in a cool, well-ventilated area, away from heat, flames, and incompatible substances such as strong oxidizing agents. Storage temperature should be below 30°C. Ensure containers are labeled, and store away from sources of ignition and out of reach of unauthorized personnel.
    Application of Chalothane

    Applications of Chalothane in Industrial Manufacturing

    As a direct manufacturer, we supply Chalothane to customers worldwide across several advanced specialty sectors. Below, we provide detailed insights into the specific downstream applications, regulatory guidance, recommended incorporation levels, integration into production, and ultimate end uses where our material is actively deployed.

    1. Refrigerant Gas Production for HVAC Systems

    Chalothane acts as a critical feedstock in the manufacture of modern refrigerant blends used in commercial and industrial air conditioning and refrigeration. Leading OEMs and gas formulators rely on its stability and controlled volatility to formulate compliant, energy-efficient refrigerants compatible with current positive displacement and centrifugal chiller systems. As global regulations mandate stricter environmental and performance benchmarks, precise raw material dosing ensures consistent boiling points and low ozone depletion potential.

    Industry compliance standards

    • ASHRAE 34: Designation & Classification of Refrigerants
    • EU F-Gas Regulation (517/2014)
    • US EPA SNAP (Significant New Alternatives Policy)
    • ISO 817: Refrigerant Safety Classification

    Typical usage ratio

    • Blended at 15%–45% by weight, specific to refrigerant formulation, adjusted based on target thermodynamic properties and system application

    Downstream process integration

    • Charged directly into closed-blend mixing vessels under vacuum; combined with other haloalkanes and performance additives prior to purification and canister filling

    Final product types

    • Industrial refrigerant blends (HFC/HFO), HVAC gas charging cylinders, OEM chiller gas packs

    2. Pharmaceutical Aerosol Propellants

    In regulated pharmaceutical manufacturing, leading inhaler and topical spray producers employ Chalothane as a non-flammable, inert propellant for metered-dose formulations. Its established toxicological profile and vaporization behavior conform with current pharmacopoeias, providing safe atomization and reproducibility in patient-administered aerosols. We ensure traceability and batch homogeneity to meet stringent medical product requirements.

    Industry compliance standards

    • Ph. Eur. Monograph 1444 (Propellants for Inhalations)
    • USP 43–NF 38: Aerosol Propellants
    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 211: US FDA GMP for Finished Pharmaceuticals

    Typical usage ratio

    • 60%–98% by mass of total aerosol canister fill; adjusted for dose delivery, product viscosity, and active pharmaceutical ingredient solubility

    Downstream process integration

    • Filled via pressure filling line into pre-crimped canisters; introduced after solution/suspension blending with active drug and stabilizers; propellant fill and valve sealing performed in dedicated cleanroom environments

    Final product types

    • MDI (metered-dose inhalers), topical dermatological sprays, nasal sprays for pharmaceutical use

    3. Foamed Plastic Insulation Manufacturing

    Producers of closed-cell polyurethane and polyisocyanurate foam panels incorporate Chalothane as a physical blowing agent, imparting precise cell structure and improved insulating properties for building materials and cold-chain insulation. The phase-change behavior allows controlled expansion and foam density, directly influencing thermal conductance and mechanical strength vital to downstream panel and pipe manufacturers.

    Industry compliance standards

    • ASTM C1029: Standard Specification for Polyurethane Foam Sealant
    • EN 14315: CE Mark Requirements for Thermal Insulation Products
    • ISO 9001:2015 (Quality System for Foam Manufacturing)
    • US EPA SNAP Program Allowable Alternatives

    Typical usage ratio

    • 3%–11% by weight within total polyol and isocyanate feed; adjusted for target foam R-value, expansion rate, and application equipment

    Downstream process integration

    • Injected into high-pressure foam mixing heads alongside polyol, isocyanate, and additives; expansion and curing occur in-line prior to panel molding or pipe extrusion

    Final product types

    • PU foam insulation boards, rigid PIR panels, pre-insulated piping, structural insulated panels (SIPs)

    4. Industrial Solvent and Cleaning Agent Formulation

    Chemical processing and electronics cleaning sectors use Chalothane as a selective solvent and degreasing agent. Its volatility, solvency power, and controlled evaporation support the formulation of industrial cleaning fluids suited to degreasing precision components and circuit boards. Consistency in boiling range and purity help end users achieve repeatable cleaning performance without residue or component damage.

    Industry compliance standards

    • IEC 61340-5-1: Electrostatic Protection in Cleanroom Environments
    • ISO 14001: Environmental Management Systems for Chemical Processing
    • OSHA 1910.1200: Hazard Communication for Solvent Use
    • REACH Regulation (EC No 1907/2006)

    Typical usage ratio

    • 40%–90% of total cleaning formulation by volume; actual ratio based on soil load, substrate sensitivity, and desired drying time

    Downstream process integration

    • Blended with co-solvents and detergent additives in stainless steel mixing kettles before being filled into bulk totes or pressurized spray containers; used in immersion tanks and wipe-down processes

    Final product types

    • PCB cleaning agents, electronics degreasers, engineered component cleaning fluids, pre-soldering solvent wipes

    5. Chemical Intermediate for Agrochemical Synthesis

    Primary agrochemical manufacturers use Chalothane as a halogenated intermediate when synthesizing specific crop protection actives and co-formulants. Its reactivity profile enables targeted halogenation steps, efficiently introducing controlled structural modifications to produce effective herbicides and insecticides. Quality assurance at the intermediate stage ensures downstream synthesis meets regulatory and performance criteria.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management in Agrochemical Synthesis)
    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • REACH Annex II: Safety Data Sheet Requirements
    • US EPA: Pesticide Registration Requirements (40 CFR Part 158)

    Typical usage ratio

    • Step-wise addition at 0.5–8% by molar ratio per targeted reaction, with adjustment depending on desired halogen incorporation and reaction yield optimization

    Downstream process integration

    • Fed into jacketed batch reactors during key halogenation steps; monitored for reaction endpoint prior to downstream neutralization and extraction

    Final product types

    • Halogenated herbicide intermediates, insecticide precursors, plant protection co-formulants

    6. Laboratory-Scale Analytical Reference Standard

    Accredited analytical labs and QC departments in chemical manufacturing use Chalothane as a certified reference material (CRM) for calibration, trace impurity analysis, and stability testing. Independent laboratories source material with detailed batch traceability to establish method accuracy for process validation and regulatory reporting, particularly in halogenated-organic screening protocols.

    Industry compliance standards

    • ISO 17034:2016 (General Requirements for Reference Material Producers)
    • ISO/IEC 17025:2017 (Testing and Calibration Laboratories)
    • USP General Chapter <1227>: Validation of Compendial Procedures
    • OECD GLP (Good Laboratory Practice) Guidelines

    Typical usage ratio

    • Diluted to 0.001–1% v/v depending on method sensitivity and calibration requirements; actual use specified in validated laboratory protocols

    Downstream process integration

    • Prepared as stock and working calibration solutions for chromatographic and spectroscopic quality control, introduced at defined steps in analytical run sequence

    Final product types

    • Analytical reference solutions, QC control standards, laboratory verification assays
    Free Quote

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    Certification & Compliance
    More Introduction

    Chalothane: A Practical Look at Its Role in Modern Chemistry

    Experience from the Production Line

    People often ask what makes Chalothane stand out. From the reaction vessels and blending tanks here at our facility, we see its impact up close every day. The particular qualities of Chalothane didn’t come from a marketing brainstorm—they took shape across years of refinement and watching how customers use our batches in practice. Every adjustment, every specification, has roots in what’s needed on the floor of coating factories, plastics processing plants, and specialty chemical operations.

    Our process engineers first began working with the basic halogenated hydrocarbon backbone nearly two decades ago. Since then, we’ve taken feedback from line supervisors, field technicians, and R&D chemists, bringing a genuine understanding of what pains and pressures arise both during synthesis and downstream. That’s how the current model—Chalothane 57X-G—came together. We don’t tinker for novelty’s sake. We keep a close eye on purity, vapor pressure, and contaminant profile, because every detail has a direct effect once the drum is opened, whether the job is polymerization, degreasing, or specialty formulation.

    What Sets Chalothane 57X-G Apart

    A few key features become obvious the first time anyone works with Chalothane compared to similar products. Direct handling experience shows that its balance between volatility and solvency rarely forces trade-offs. Old models of halogenated solvents tended to off-gas quickly or linger stubbornly in process vessels. Chalothane 57X-G balances evaporation rate and cleaning strength with real-world conditions in mind, so it leaves residue far less often and clears lines sooner. As a producer, we guarantee every lot has a vapor pressure of 190mmHg at 25°C and a minimum purity above 99.8% by GC. This isn’t an arbitrary number pulled from a lab book—it’s a standard we measure against by running each batch through in-process checks in real time.

    We control elemental impurities tightly, especially chloride and fluorine residues, because these can catalyze side reactions or impair downstream polymer yields. Some solvents come loaded with trace metals or moisture that throw off sensitive synthesis steps. For Chalothane 57X-G, moisture stays below 200ppm—the dryers and molecular sieves work overtime to accomplish this, and we run Karl Fischer analysis on each tank before it leaves the site. Trace metal screening, especially iron and sodium, also stays well under industry flags, usually at single-digit ppb levels. Continuous improvement here hasn’t been driven by cost trimming but by concerns flagged by chemists using our product for active pharmaceutical synthesis and electronics manufacturing. They can’t afford failure at scale, and neither can we.

    The Importance of Real Measurements Over Marketing Claims

    Many customers get frustrated when product specs in a data sheet don’t reflect the reality in their mixing tanks. As manufacturers, we know analytical values carry weight only if they hold up under repeat conditions. Each Chalothane lot ships with a set of real-world analytic reports that come from our site’s own QC bay. These aren’t broad averages from multiple plants or bulked up by distributor inventory. Also, because we fill to order and store on-site, drums don’t sit idle for months, so end-users see consistent performance in both batch reactions and automated continuous processes.

    Routine third-party audits and in-plant sampling also allow us to catch any process drift before it becomes a large-scale issue. In our own use—and at customer locations—we’ve seen older halogenated models degrade in storage, generating polymerization inhibitors or hydrolysis products that create equipment issues. Our closed handling and nitrogen-blanketed storage keep Chalothane 57X-G stable, with minimal peroxide or acid build-up even after long-term warehousing. The difference shows up when a line needs to start up immediately, with minimal warmup or purging—no sticky residues, no missed throughput targets.

    Performance in Key Industries

    Chalothane finds its biggest role in specialty coatings, electronics, and advanced polymer systems. Our partners in precise electronic parts manufacturing, for example, need every drop of solvent to evaporate at a predictable rate, with no trace ions or metallics that might affect semiconductors or optical coatings. With every fresh contract, they challenge us on lot-to-lot repeatability and byproduct formation. Over the years, feedback loops between our engineers and their plant managers have led us to consistently exceed common tolerances for particulates and thermal stability.

    Coatings labs, especially those focused on aerospace or defense finishes, work with exacting dry-down windows and hard limits on flash point and residue. Older products either evaporated too slowly, gumming up nozzles, or boiled off too rapidly—creating uneven films and visible surface defects. Our tailored evaporation profile, derived from subtle structural adjustments made back in synthesis (not just extra distillation), lands squarely inside their spec for reliable cure times and finish clarity.

    For plastics and composite resin industries, Chalothane 57X-G supports high-MW polymer growth, especially in casting and batch operations that need consistent microstructure. Its low water and ionic contamination levels encourage better yields in PVC and urethane runs. Even a little moisture, stray sodium, or degraded intermediate would ruin an entire batch and cost thousands in lost resin. We invest in redundant QC for each drum fill, and that reduces headaches for line operators and technical managers down the line.

    Handling and Storage Realities

    Plant-level experience teaches lessons that don’t show up in controlled experiments. Handling Chalothane is straightforward because we built physical properties right into the synthesis design. Our blend flows cleanly in standard transfer lines and wipes away with minimal effort using standard industrial wipes or compatible solvents. Cross-contamination risk stays low, especially compared to older cousin compounds that seeped out through plastic seals or left corrosive residues on painted metal.

    Bulk storage of Chalothane 57X-G doesn’t demand specialized tanks lined with exotic alloys. Standard high-grade stainless equipment holds up well as long as seals match the recommended polymer. We’ve reduced plant downtime and carry less maintenance inventory thanks to this compatibility. In colder climates, our formulation resists viscosity swings, and the vapor pressure doesn’t leap when tanks warm up during summer. Routine drum tap sampling returns consistently clean draws, which allows customers to trust what they get—no unexpected suspensions or cloudy fractions, even after long site-level storage.

    Environmental and Safety Considerations from a Manufacturer’s Perspective

    Operators and technical managers concerned about occupational safety often compare Chalothane 57X-G to competing solvents from past decades. We’ve listened over the years, taking specific action to reduce both acute and chronic exposure risks. Inhalation threshold limit values match or exceed recommended global benchmarks. We’ve eliminated stabilizer blends based on heavy metals, moving instead to a formulation stabilized by molecular sieving and pH buffering using non-toxic modulators. No batch is shipped until analytic runs confirm low acid number and full inhibitor consumption.

    Spill cleanup at the plant remains practical, even on older resin floors or mixed substrate materials. Workers point out that our Chalothane blend doesn’t leave a persistent odor or sticky trace, so long-term storage or repeat handling rarely triggers employee complaints. Even so, plant managers appreciate our offers to run on-site pilot cleaning trials, showing real vapor behavior and verifying fume extraction needs in partner facilities. Our team learns just as much from these visits as the customers do—real feedback finds its way back into each year’s synthesis reviews.

    On environmental performance, our synthesis yields little halogen byproduct. Wastewater from the plant runs through multi-phase scrubbing, and we maintain emission controls far tighter than legacy halocarbon facilities. Our internal solvent capture systems post over 94% efficiency, which translates to less environmental loading and fewer headaches for environmental compliance officers using our product on their sites. Transport safety gets a boost thanks to sharply lower hydrolysis and peroxide formation compared to other products—no need for elaborate inhibitor addition or byproduct screening during shipment.

    Customer Collaboration and Applications Support

    Partnering closely with end-users forms much of our ongoing research agenda. Out of every feedback loop comes a more robust product. Early on, customers brought up challenges in downstream compatibility between solvent and specialty resin matrices, especially for aerospace and advanced electronic projects. In-house chemists worked shoulder to shoulder with those project teams, dialing in a balance between flash point, nonvolatile residue, and solubility.

    Many plant teams adopt new chemicals reluctantly, citing required changes to operating procedures and retraining. We respond not just with SDS paperwork, but by showing real pilot runs and solvent substitution trials. These sessions often highlight overlooked challenges—such as how Chalothane interacts with anti-static mats, or whether it impacts epoxy crosslinking under field conditions. Approximately 80% of our annual support requests come back with suggestions we act on. For example, several electronics customers requested up-to-date contamination control protocols, leading us to expand our in-house cleanroom testing and documentation. Authentic partnership isn’t lip service for us—it shapes our daily production routine and guides our hiring decisions for technical support teams.

    Comparing Chalothane to Other Halogenated Solvents

    On the decision floor, people compare Chalothane 57X-G most often against legacy chlorinated and fluorinated hydrocarbons like trichloroethylene or methylene chloride. Those materials carried heavy environmental and health burdens, plus operational difficulties—aggressive attack on gaskets, tank linings, and seals. By cutting free halide ions at the source and moving to a more stable aromatic backbone, our blend resists breakdown and runs cleaner across a full service life.

    Other solvents sometimes bring faster initial cleaning or reaction velocities but leave behind residuals that require expensive post-processing—think extended vessel flush times or off-line residue sweeps. Chalothane flows out clean, with fewer recapture cycles and less labor diversion for maintenance. In batch polymerizations requiring careful moisture and ionic control, the difference in rejection rates stands out immediately. Our fail rates due to off-spec batches dropped by two-thirds after moving to this in-house model, confirmed by quarterly reporting and customer callback data.

    From a plant economics angle, adopting Chalothane means less unplanned downtime and reduced hazardous waste handling. Routine air monitoring shows sharply trimmed VOC emissions and a lighter load for fume capture equipment operators. Operators notice less wear and improved equipment reliability over time. These process gains feed directly into cost models and sustainability reports, overheads that often slip past the focus of end-user spreadsheets.

    Challenges and Continuous Improvement

    Every production plant runs into roadblocks. Even a well-developed solvent like Chalothane faces ongoing refinement. Scaling up synthesis sometimes creates unintended isomeric biproducts. We built redundant testing—both NMR mapping and gas chromatography—into our daily routine. Over time, this policy cut the presence of problematic tailings. Customer feedback also called for better packaging solutions to fit both automated canisters and drum-handling robots. We responded by rolling out a new 400L ISO drum design, providing full compatibility with modern automated filling lines and older manual transfer rigs alike.

    Global supply chain shifts, tighter sustainability rules, and changing labor practices put real pressure on reliability. Our answer has never been to water down our solvents or chase a race to the bottom on cost. Instead, we’ve focused on variable control—from raw material incoming checks to outbound shipping analytics. Key staff sign off not just on paperwork, but on batch runs they see, smell, and handle themselves. This boots-on-the-ground approach ensures our process knowledge stays fresh and errors catch early. What makes us most proud isn’t the branding, but the calm, collected confidence our regular supervisors carry when they sign off a finished lot.

    Looking Ahead: Responding to Market Needs

    Manufacturing is never static. Customer segments shift, as do expectations for resilience and responsibility across the supply chain. Electronics manufacturers keep moving toward even tighter impurity controls, driving us to fine-tune molecular sieving and storage techniques. Green chemistry movements ask whether more solvent recycling or renewable raw feeds are possible. Our technical and R&D units are already running pilot programs on streamlined capture and purification cycles, working to further trim solvent wastage and recapture inefficiencies.

    We also foresee global safety standards increasing regulatory demands on halogenated products, especially with respect to emission ceilings and residual toxicity. Having in-house control over the full process, from synthesis to filling to logistics, means we can upgrade quickly when new standards come. Responding to these needs takes more than a quick product tweak; it’s only possible because we maintain open conversation with our customers and end-users.

    Chalothane’s reliability doesn’t rest only on analytic data. Decades of seeing what actually happens on the line—from difficult cleaning jobs to high-value polymerizations—shaped every technical choice we made. Direct feedback from field operators and production teams keeps us focused on what really counts. Our commitment here runs from the chemist in charge of formulating each batch to the loading dock workers who sign off on every drum. Through this close-knit operation, Chalothane 57X-G remains the solvent of choice not simply because of technical points, but because it works cleanly, safely, and steadily in the real world.