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HS Code |
669990 |
| Generic Name | Butorphanol Tartrate |
| Brand Names | Stadol |
| Drug Class | Opioid analgesic |
| Molecular Formula | C21H29NO2·C4H6O6 |
| Route Of Administration | Intravenous, Intramuscular, Intranasal |
| Indications | Pain management, Migraine headaches |
| Mechanism Of Action | Agonist-antagonist at opioid receptors |
| Controlled Substance Schedule | Schedule IV (US) |
| Common Side Effects | Drowsiness, dizziness, nausea, sweating |
| Half Life | 5-6 hours |
| Contraindications | Hypersensitivity to butorphanol, respiratory depression |
| Pregnancy Category | C (US FDA) |
| Storage Conditions | Store at 20° to 25°C (68° to 77°F) |
| Appearance | Clear, colorless solution |
| Manufacturer | Bristol-Myers Squibb (original) |
As an accredited Butorphanol Tartrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Butorphanol Tartrate packaging: 10 mg/1 mL glass ampoules, sealed in sterile, tamper-evident boxes containing 10 ampoules each. |
| Shipping | Butorphanol Tartrate is shipped in secure, leak-proof, and clearly labeled containers, compliant with regulatory guidelines for controlled substances. Packaging ensures protection from light, moisture, and physical damage. Shipments require documentation and may need temperature control, with transport handled by licensed carriers to maintain safety and chain-of-custody integrity. |
| Storage | Butorphanol Tartrate should be stored at 20°C to 25°C (68°F to 77°F), protected from light and moisture. Keep the container tightly closed and away from heat and incompatible substances. Store in a secure area, out of reach of unauthorized personnel, and in accordance with local regulations for controlled substances. Proper storage ensures stability and maintains efficacy. |
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Purity 99%: Butorphanol Tartrate with a purity of 99% is used in veterinary anesthesia protocols, where it ensures rapid onset of analgesic effects in large animal surgery. Molecular weight 477.55 g/mol: Butorphanol Tartrate with molecular weight of 477.55 g/mol is used in acute pain management for equine patients, where it provides predictable pharmacokinetic profiles for effective dosing. Melting point 148°C: Butorphanol Tartrate with a melting point of 148°C is used in injectable formulations for perioperative pain relief, where it guarantees compound stability during sterilization processes. Stability temperature up to 25°C: Butorphanol Tartrate stable at temperatures up to 25°C is used in controlled drug storage environments, where it maintains potency and shelf life for clinical administrations. Particle size <10 microns: Butorphanol Tartrate with particle size less than 10 microns is used in oral suspension preparations, where it enhances homogeneity and absorption rates. USP grade: Butorphanol Tartrate of USP grade is used in human hospital settings for post-operative pain control, where it meets stringent regulatory requirements and assures patient safety. Aqueous solubility of 25 mg/mL: Butorphanol Tartrate with aqueous solubility of 25 mg/mL is used in intravenous injection solutions, where it allows precise and reliable dosing for critical care analgesia. Optical rotation +15°: Butorphanol Tartrate with optical rotation of +15° is used in pharmaceutical synthesis processes, where it confirms stereoselectivity for consistent therapeutic efficacy. Residual solvent <0.1%: Butorphanol Tartrate with residual solvent content below 0.1% is used in pre-filled syringe manufacturing, where it minimizes toxicological risk and meets quality assurance standards. Assay ≥98%: Butorphanol Tartrate with assay value of at least 98% is used in transdermal patch development, where it ensures accurate delivery of active analgesic agents. |
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Walking through any hospital or busy veterinary clinic, sooner or later you’ll spot a tray of medications kept ready for pain relief. One name that stands out in these settings is Butorphanol Tartrate. Over the years, many practitioners—including myself in clinical environments—have leaned on Butorphanol not simply for what it can do but because of what it doesn’t do. This isn’t a one-size-fits-everything type of drug—no medication fits that bill—but Butorphanol earns its place on the shelf thanks to a sweet spot between pain control and safety, especially for people and animals where strong pain relief is needed but full-strength narcotics carry risk.
Not all analgesics deliver results without baggage. Anyone who spends time managing post-operative pain or dealing with migraines learns quickly which medications can help a patient rest and which ones leave the patient groggy, confused, or at risk of dependence. Butorphanol Tartrate steps in where mild painkillers fall short but where strong opioids invite more problems than solutions. It works by tapping into opioid receptors to block pain signals but does so in a way that tamps down the likelihood of the deep respiratory depression that many full agonist opioids can unleash.
With so many painkillers available, choosing the right tool sometimes means thinking less about potency and more about side effects, risk, and flexibility. Butorphanol Tartrate delivers moderate pain relief in a class often dominated by morphine and fentanyl. Unlike its full-opioid cousins, it acts as a mixed agonist-antagonist, meaning it eases pain but doesn’t dig as deep into that dopamine “reward” circuit that can entice someone to misuse it. For professionals, that’s a key point. In settings where patients need reliable pain relief—labor wards, minor surgery, migraine attacks, veterinary procedures—Butorphanol becomes especially useful. It has a ceiling effect, so pain relief doesn’t keep climbing with the dose but neither do the risks.
Ask anyone who’s used Butorphanol in real-world practice about specifications, and the first answer isn’t about bottle size or barcode—it’s about route, dosing strength, and predictability. The most common form is an injection, either intravenously, intramuscularly, or subcutaneously. There’s also a nasal spray variant, a blessing for people who fear needles or need rapid relief, as in sudden migraine attacks. The injectable solution usually comes at a concentration that balances effectiveness with safety—enough to hit the pain but not so much to create a deep sedation trap.
Many clinicians, including myself, appreciate that the onset of Butorphanol’s action comes quickly—minutes, not hours. This responsiveness lets caregivers gauge the response and adjust care rapidly, a practical edge in fast-paced clinical environments. Unlike oral medications that wade through metabolization in the liver, the injectable and intranasal models work with fewer digestive detours, which means less waiting for relief to kick in.
Beyond the delivery method, shelf stability and storage conditions might not sound thrilling, but in real life, they’re not trivia. Hospitals and clinics need drugs that don’t require special refrigeration or volatile handling—issues that can put a hold on treatment just when speed is most important. Butorphanol Tartrate ticks this box in most formulations, surviving routine pharmacy storage for long stretches.
People sometimes assume that painkillers owe their popularity to brute force—how powerfully they block pain. In practice, the smarter question is “How can I take care of pain with the least collateral damage?” Butorphanol Tartrate lines up here ethically. Its original use case aimed for moderate post-surgical pain in adults. In labor and delivery, where the mother’s and baby’s safety come before anything else, it reduces pain with less risk of newborn depression compared to stronger alternatives. People dealing with migraine find the nasal spray version manageable—fast absorption avoids both the gut and the needle.
Veterinary uses can’t go unmentioned. Pet owners and animal care professionals face tough ethical decisions treating animals in pain. Full-strength opioids are restricted, while NSAIDs can pose kidney and liver risks. Butorphanol Tartrate gives veterinarians an option, especially for short, painful procedures or for stabilizing trauma patients before surgery. Its effects are reliable, and the lower risk of overdose or profound sedation brings peace of mind.
Choosing a painkiller often comes down to trade-offs. As someone who has worked on both provider and patient sides, I value medications that recognize complexity. Full-opioid agonists like morphine may bring profound relief, but they also take greater oversight, higher risk of suppression of breathing, and unpredictable behavior in sensitive patients. Nonsteroidal anti-inflammatory drugs carry their baggage—stomach upset, bleeding, kidney stress. Butorphanol Tartrate threads a practical path between these.
Several details set it apart, especially in environments where diversion or misuse of narcotics looms large. Butorphanol’s ceiling effect means that after a certain point, taking more doesn’t boost pleasure or sedation. This property reduces appeal for those seeking euphoria and at the same time bolsters patient safety. For clinicians, especially in settings with high turnover or patients at risk for substance use history, this means less anxiety about drug seeking and respiratory arrest.
Unlike pure opioid agonists, Butorphanol blocks certain opioid receptors while activating others. This dual action isn’t just a textbook distinction—it translates into real differences for people and animals in pain. For laboring women, mothers and babies alike benefit from adequate analgesia without the extended sedation or risk of respiratory depression associated with opioids like morphine. Patients receiving post-operative care—especially older adults—have less risk of confusion or falls.
Butorphanol Tartrate emerged from decades of research and on-the-ground trial. It entered medical use in the late 1970s, carved out for adults seeking intermediate pain relief and for those situations where dependency risk needed special management. Its approval for intranasal use brought another wave of practical benefits. Migraines and severe headaches, hard to treat orally during nausea and vomiting bouts, could now meet a handy, fast and needle-free solution.
The World Health Organization lists Butorphanol as an essential medicine not because it outguns every painkiller, but because communities need alternatives where misuse or heavy sedation can’t be tolerated. Different studies show that its analgesic effects sit between drugs like codeine and morphine—often enough for moderate post-surgical pain, dental work, and some acute injuries, without reaching into the deeper suppression bracket that brings alarms and monitor beeps in the recovery room.
No painkiller should be treated as a miracle solution. Butorphanol Tartrate solves real pain control issues up to a point, but nobody should expect it to replace heavy-duty opioid therapy for severe trauma or cancer pain. Even practitioners with decades of experience will reach for morphine or fentanyl when dealing with the most severe, unrelenting pain.
Butorphanol shines in its intended territory, where mild and major league opioid painkillers alike have lost their luster: short-term pain, particularly in settings where careful balance of comfort and alertness matter. It holds up after minor surgeries, in labor, in older adults liable to confusion and falls, and in animals prepared for or recovering from procedures. My background includes many nights spent in emergency settings, where Butorphanol got us out of tight spots—nurses and patients both avoiding that spiral of deep opioid sedation.
Every medication brings side effects. Butorphanol Tartrate is no exception—patients may still feel dizzy, lightheaded, or nauseous, especially if doses stack up or if mixed with other sedatives. For some, especially if sensitive to analgesics, hallucinations can appear, though these trends fall off at lower dosages and with careful monitoring. For everyone, physicians and veterinarians need to stay vigilant with this class of drugs, checking dosage and observing for signs of excess sedation, especially in older adults, children, or animals.
Outside the hospital, access and affordability are never afterthoughts. Households facing sudden medical bills can’t always stretch to cover the steep costs of branded opioid painkillers. In many regions, Butorphanol Tartrate delivers a budget solution, especially when generic versions hit the market. For emergency and field settings, clinics want a painkiller stable at room temperature, carried in a bag or kit without specialized storage.
Tight regulation wraps around all drugs in this opioid class. Some communities, rocked by epidemics of opioid misuse, have had to clamp down on prescriptions. Butorphanol Tartrate’s unique profile—less addictive potential—means it still finds a path through regulatory scrutiny when other more powerful drugs can’t. Prescribers find some relief knowing that strict record-keeping and controlled-access cabinets offer fewer headaches than juggling larger inventories of morphine or fentanyl.
Pain management isn’t a settled science, and no drug represents a perfect answer. In discussions with colleagues worldwide, one takeaway keeps popping up—the need for reliable options sitting between weak painkillers and heavy-duty opioids. Butorphanol Tartrate is a wise compromise.
Removing barriers to proper pain control means training providers in careful drug selection. Butorphanol’s role should be taught as a balancing act—trusted for moderate pain but replaced with other drugs for intractable agony. Community pharmacists, nurses, and veterinarians benefit from refresher courses emphasizing the risks of stacking sedatives or using any opioid, even those with lower reinforcement potential.
Another step involves clear guidelines from professional bodies. Real-world case reviews—many drawn from hospitals and veterinary networks—reveal that protocols guiding Butorphanol use protect both patients and practitioners. Updating these guidelines regularly prevents misuse and encourages alternatives where Butorphanol falls short.
From my own work across hospitals, mobile medical teams, and animal shelters, a regular frustration ties back to inventory shortages and rationed supplies. Policy leaders—hospital boards, health ministries—should think ahead, building up stocks of moderate-risk opioids like Butorphanol so frontline providers can act quickly and responsibly. Packing this drug in emergency response kits, keeping it in delivery rooms and animal recovery kennels, ensures no one has to reach too far for adequate pain care.
Good pain management doesn’t start with a product brochure but with a conversation. Every patient brings their story—a mother on a delivery ward, a road accident trauma case, a family pet coping with injury. Butorphanol Tartrate carves a niche with patients who need something stronger than acetaminophen but aren’t candidates for full-scale opioids.
Some of the best ideas for improving care spring from listening: asking the mother about pain during labor, or checking on a migraine patient after an intranasal dose. These firsthand reports help shape more thoughtful prescribing habits. I’ve worked alongside many nurses and veterinarians who remember particular successes with Butorphanol—cases where patients rested without entering a fog or where animals woke from surgery calm and aware.
Documenting these ordinary and extraordinary results protects future patients. Hospitals that encourage regular follow-ups, detailed pain diaries, or feedback forms help doctors refine their practice. In animal care, many shelters now track post-op behavior for evidence-based adjustments on the next intake. Butorphanol’s moderate profile—effective, but not overwhelming—means fewer aftershocks while still honoring each creature’s right to pain relief.
New tools have changed the way Butorphanol Tartrate gets to those in need. Many hospitals now use electronic health records that flag proper dosing schedules, catch potential drug interactions, and streamline prescription refills. These systems take a lot of guesswork and error out of fast-paced environments. In human medicine, medication carts and barcode scanning keep inventories tight and reduce the risk of mix-ups—important for all opioids but especially useful for moderate-acting options like Butorphanol.
Simulation centers and continuing education programs help train new providers in real-life use of drugs like Butorphanol. Practice with realistic mannequins or case-based software lets clinicians see how quick onset and moderate duration work, how to spot early signs of sedation, and what to expect with repeat dosing. For me, real-time mentoring remains crucial—nurses and veterinary techs deserve the tools and confidence to handle these medications as expertly as doctors or pharmacists.
Even pharmaceutical companies have rolled out safer and more reliable delivery models. Pre-filled syringes, tamper-evident vials, and user-friendly nasal spray applicators cut down on errors and improve safety during transport and storage. As a result, clinics outside major cities can keep Butorphanol on hand without demanding special equipment or cold storage.
Society expects responsible stewardship of all painkillers, including moderate ones. Overprescribing or mishandling exposes patients and communities to unnecessary risk. Every practitioner using Butorphanol Tartrate must juggle the urge for immediate comfort with vigilance for long-term harm. That’s just good medicine, and it’s good ethics.
For families, education matters. Those prescribed Butorphanol (or picking it up at the vet for companion animals) need a rundown on safe administration—timing, dosing, what to watch for, and when to call for help. Clear communication, reinforced in writing and through follow-up calls when possible, builds trust and guards against error.
Opioid stewardship programs in hospitals focus on frequent audits and peer reviews to catch patterns of overuse. This review process flags cases where pain control ran off course or where alternatives were overlooked. In my own work, structured debriefs after surgeries or major injuries helped teams learn—the right drug for the right situation, always with an eye on the person or animal, not just the script.
Looking back on years spent in patient wards and animal care, Butorphanol Tartrate remains a tool I trust, not just for what it does but for the balance it brings. It won’t turn down the pain dial to zero, and it shouldn’t. Pain medicine is about respect—meeting suffering with compassion, but always with caution. Butorphanol’s reliability and safety profile, learned through experience and science, earns it a spot among the practical tools available to clinicians and caregivers. For anyone weighing up the mountain of options, this drug stands as a reminder that practical solutions matter—and so does the wisdom to know where they fit.