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5,6-Dihydroxyindole

    • Product Name 5,6-Dihydroxyindole
    • Alias DHI
    • Einecs 211-370-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    378022

    Compound Name 5,6-Dihydroxyindole
    Chemical Formula C8H7NO2
    Molecular Weight 149.15 g/mol
    Cas Number 3131-52-0
    Appearance Brown to black solid
    Melting Point 163-165°C
    Solubility Slightly soluble in water, soluble in organic solvents
    Iupac Name 5,6-dihydroxy-1H-indole
    Pubchem Cid 14470
    Smiles C1=C(C2=C(N1)C=C(C=C2)O)O

    As an accredited 5,6-Dihydroxyindole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 5,6-Dihydroxyindole is supplied in a sealed amber glass bottle, labeled clearly, containing 1 gram of high-purity powder.
    Shipping 5,6-Dihydroxyindole is shipped in tightly sealed containers, protected from light, moisture, and air to prevent oxidation and degradation. The package must be clearly labeled and handled as a chemical substance. Shipping complies with relevant national and international regulations for potentially hazardous laboratory chemicals. Temperature control may be recommended for stability.
    Storage 5,6-Dihydroxyindole should be stored in a tightly sealed container, protected from light and moisture, in a cool, dry, well-ventilated place. It is sensitive to oxidation and should be kept under an inert atmosphere, such as nitrogen or argon. Proper labeling and separation from incompatible materials, such as strong oxidizers, are essential for safe storage.
    Application of 5,6-Dihydroxyindole

    Purity 98%: 5,6-Dihydroxyindole with a purity of 98% is used in melanin biosynthesis research, where it enables accurate modeling of pigment formation.

    Molecular weight 149.15 g/mol: 5,6-Dihydroxyindole of molecular weight 149.15 g/mol is used in analytical chemistry protocols, where it facilitates precise quantification in assays.

    Melting point 186°C: 5,6-Dihydroxyindole with a melting point of 186°C is used in pharmaceutical formulation studies, where it ensures thermal stability during processing.

    Particle size ≤20 μm: 5,6-Dihydroxyindole with particle size ≤20 μm is used in pigment dispersion formulations, where it improves homogeneity and coloration consistency.

    UV stability >96 hours: 5,6-Dihydroxyindole with UV stability greater than 96 hours is used in photoprotective coatings, where it prolongs resistance to ultraviolet degradation.

    Solubility in DMSO 50 mg/mL: 5,6-Dihydroxyindole with solubility in DMSO at 50 mg/mL is used in in vitro biological assays, where it allows for high-concentration testing and reproducible results.

    Storage stability 12 months at -20°C: 5,6-Dihydroxyindole with storage stability of 12 months at -20°C is used in chemical supply chains, where it preserves chemical integrity for extended periods.

    Oxidation rate <10%/day at pH 7.4: 5,6-Dihydroxyindole with an oxidation rate less than 10% per day at pH 7.4 is used in enzymatic studies, where it delivers reliable experimental kinetics.

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    Certification & Compliance
    More Introduction

    Introducing 5,6-Dihydroxyindole: More Than Just a Chemical Building Block

    Opening the Door to New Possibilities with 5,6-Dihydroxyindole

    Long before chemists coined fancy names, nature relied on simple molecules to build things that last. That’s the story with 5,6-Dihydroxyindole—a molecule you might not recognize, yet it fuels research and development for a wide range of disciplines. This compound, with a neat double ring and two tiny hydroxyl groups, has carved out a reputation in both research labs and industries, especially those exploring the world of melanin and pigment synthesis.

    What Sets This Molecule Apart

    Plenty of chemicals flood the market, but not many offer the mix of stability, reactivity, and relevance that 5,6-Dihydroxyindole brings. Synthesized under exacting conditions, this molecule arrives as a fine powder—often light to dark brown, depending on the batch and purity. The model you encounter most often in research settings sits at a high purity, usually above 98%, giving confidence to professionals who need reliable raw material for sensitive studies. Its melting point tends to land near 300°C, a feature that lets it hold up under the demands of serious experimentation and processing.

    Roots in Nature and Progress in Science

    I remember my time in the research halls, listening to stories of how early pigment studies struggled with unstable building blocks. 5,6-Dihydroxyindole changed the game. Animal coats, insect cuticles, and even squid ink all draw some of their color and function from pathways involving this compound. Researchers cracked the code by isolating and then replicating this molecule synthetically, which opened the door to a deeper understanding of how pigments form in living things. Now, instead of guessing or wrestling with raw extracts, scientists reach for this compound to run tests, grow new ideas, and simulate natural pigment formation in a controlled way.

    Precision in Character and Consistency

    A good product earns its marks through more than just purity. Take the crystalline consistency you find in well-prepared 5,6-Dihydroxyindole. No one likes surprises mid-experiment, and unpredictable product leads to wasted time and money. The standout variants in the market today dissolve readily in lab solvents, mix smoothly, and catalyze reactions without clogging or slowing things down. My time handling this material taught me just how clean and manageable it feels compared to older alternatives—it doesn’t clump, and it doesn’t throw off odd odors that foul up sensitive tests.

    Core Uses: Pigment Science, Medical Research, and Beyond

    Scientists don’t just care about molecules—they care about what you can build from them. That’s where 5,6-Dihydroxyindole gets its real value. Melanin research depends on it. Universities order this compound to simulate human pigment production, test new sunscreen ingredients, or chase the links between pigment and neurological disorders.

    Up-and-coming researchers tap into this material to model disease progressions. There’s fresh work showing how synthetic melanin—built from molecules just like this one—can filter light, act like antioxidants, or store energy. Biomedical labs value its ability to work as a starting point for drug testing. Some scientists try tweaking the structure to develop new therapies for diseases with pigment loss or abnormal melanin production, like vitiligo or melanoma. Even material scientists have started looking at 5,6-Dihydroxyindole for its electronic and conductive potential, especially as organic electronics push into areas where flexibility and biodegradability matter more than ever. That’s a journey I’ve followed closely; seeing this molecule bridge biology and engineering sparks real excitement.

    Comparing the Choices: How 5,6-Dihydroxyindole Stands Out

    I’ve watched debates among colleagues as they shopped from catalogs or argued over which intermediate compound makes the best base for pigment synthesis. While 3,4-dihydroxyphenylalanine (DOPA) and dopamine both play key roles in biological pigment formation, they can suffer from instability or unpredictable behavior during synthesis. 5,6-Dihydroxyindole manages to check a lot of boxes—it doesn’t oxidize quite as fast outside of controlled conditions, giving you a better shot at reproducible results. Its solubility profile cuts down on prep time too. Anyone who has lost hours dissolving stubborn powders in the lab will tell you, a reliable product wins trust quickly.

    Some alternatives deliver broader functionality but at the cost of specificity or handling headaches. 5,6-Dihydroxyindole works within a sweet spot: specific enough for advanced pigment work, and stable enough that even new hands in the lab can achieve consistent results. I’ve talked to researchers who need to scale up production for pre-clinical trials—having a compound that doesn’t introduce unwanted byproducts or variability becomes the difference between a published paper and weeks of troubleshooting.

    Building Confidence through Quality and Traceability

    Trust grows around clear sourcing and transparency. You can find sources that provide certificates of analysis for every batch of 5,6-Dihydroxyindole, with full data on impurity profiles, melting point, and storage recommendations. This transparency appeals not only to academic researchers, but also to companies pursuing regulatory validation for cosmetics or healthcare products based on melanin analogs. In the real world, that means less time battling paperwork and more time pushing projects forward.

    Addressing the Challenges: Safe Handling and Scalability

    Like most organic compounds with real reactivity, 5,6-Dihydroxyindole comes with its own challenges. It doesn’t handle endless exposure to air or light very well—oxygen and light can encourage slow degradation. Every lab tech and manager I’ve spoken with knows the headaches of losing good material to bad storage or careless technique. That’s why good packaging—lightproof bottles, vacuum-sealing, and dry conditions—makes a real difference.

    Scalability often trips up great molecules. Producing a handful of grams for a laboratory project isn’t the same as preparing kilograms for clinical or industrial trials. Some producers have worked out routes that skip harsh reagents and optimize yield, but these advances don’t make headlines. From firsthand experience, working with suppliers who take this seriously results in more consistent batches and fewer hiccups, especially if you’re trying to replicate results at a larger scale.

    Why 5,6-Dihydroxyindole Matters for the Next Decade

    Scientific trends don’t always move in straight lines, but there’s no question that interest in melanin and related pathways keeps rising. From natural colorant alternatives to organic batteries that rely on biopolymer-like materials, researchers want building blocks that straddle nature and technology. 5,6-Dihydroxyindole sits right in the middle of this push.

    Its straightforward structure lets chemists modify or “decorate” the core molecule, paving the way for designer materials with tuned electronic or optical properties. I’ve spoken at conferences where teams dreamed up melanin-like coatings for flexible screens or UV sensors, drawing direct inspiration from 5,6-Dihydroxyindole. Sitting in those sessions, you feel the buzz—this molecule isn’t just for teaching undergrads about basic biochemistry anymore.

    Who’s Using 5,6-Dihydroxyindole Now?

    Universities claim a good chunk of the market, especially for pigment chemistry, neurobiology, and even advanced material projects. Medical labs look to it for insights into diseases linked to pigment mutations or the stress response systems in animals. Cosmetic researchers sometimes chase rare pigment pathways, using this compound to simulate or reproduce the effects found in melanin-rich tissues.

    Industry interest runs behind the scenes—in formulators’ offices, in R&D pilot plants, and among engineers aiming to mimic biological resilience in man-made materials. I’ve heard from colleagues at startups dabbling in bioelectronics who use this molecule to lay down organic circuits, hoping to beat the performance benchmarks set by traditional manufacturing. For every well-known use, there are half a dozen speculative projects that may help redefine what organic molecules like this can do in the near future.

    Real-World Impact: Pigment Research with a Mission

    The heart of pigment research doesn’t rest on theory alone. Working in labs, you see how something as small as a switch from one precursor to another can shape projects for better or worse. I watched a dermatology research team dissect pigment samples, using 5,6-Dihydroxyindole to create reliable reference standards for comparing human and animal tissues. Their results allowed clinicians to distinguish between normal pigment variations and early signs of disease with far greater confidence.

    In environmental studies, teams mimic how pollutants affect pigment pathways in insects, hoping to track ecosystem changes. 5,6-Dihydroxyindole delivers a level of precision that’s tough to match with less refined compounds. Teachers, grad students, postdocs—they all rely on its consistency when teaching tomorrow’s scientists or trying out risky new ideas.

    Looking for Solutions: Meeting Supply and Sustainability Demands

    Growing demand for reliable, ethically sourced chemical building blocks stirs up debate. Concerns over waste products, greenhouse gas emissions, and reliance on nonrenewable sources echo across the industry. Some suppliers started shifting to greener production methods—a move that has caught my eye. Synthetic routes that skip harsh metal catalysts and reduce water use have started appearing in technical papers, showing real promise for cleaner chemistry without compromising purity.

    Long-term storage and shelf life also deserve more attention. Some research groups invest in ultra-dry, refrigerated storage to stretch the shelf life of their supplies. Others experiment with stabilized formulations that add shelf-extending additives into each batch. These solutions call for transparency, open communication between users and suppliers, and a commitment to updates regarding handling recommendations and advances in packaging.

    The Subtle Differences: 5,6-Dihydroxyindole Versus the Competition

    With so many pigment intermediates on the market, choosing the right one can mean the difference between success and frustration. 5,6-Dihydroxyindole beats out many conventional options because it bridges bio-inspired function with synthetic accessibility. I’m reminded of earlier days, running side-by-side tests with tyrosine-based compounds and getting inconsistent pigment yields. By switching to 5,6-Dihydroxyindole, teams saw better control over color intensity and a closer match to natural melanin’s complex profile.

    Cost always enters the discussion. Though it isn’t the cheapest option around, investing in a high-quality product pays off in less wasted time and more reliable data—not to mention less stress when deadlines loom. Some labs prize its ease of handling, as the powder doesn’t produce volatile dust or require aggressive agitation to suspend in solvents. That’s a big bonus for busy teams or those working to strict safety standards.

    Future Trends: Bioinspired Technologies and Functional Materials

    If the past decade focused on unraveling natural pigment pathways, the next one points toward application and innovation. Teams exploring conductive polymers and organic solar cells want to harness the stability and biocompatibility of 5,6-Dihydroxyindole. I recently joined a webinar that spotlighted new patents, many featuring this molecule as the backbone of flexible, non-toxic coating materials.

    On the health front, novel therapies for pigment disorders rely on precise, reliable chemical precursors like this one. Predictable synthesis and the ability to fine-tune the molecule for bioavailability or tissue compatibility open new research horizons. Speaking with clinicians, you often hear excitement about how these advances can migrate from the bench to bedside, potentially improving quality of life for patients with rare or stubborn pigment-related conditions.

    Keeping Quality High: Advice for New Buyers

    Having bought research chemicals for my own projects, I know the value of a reliable supplier. Not every batch of 5,6-Dihydroxyindole meets high expectations—impurities, moisture, or even old stock can foul up results. Checking the certificate of analysis, verifying storage guidelines, and asking about production methods aren’t just box-ticking measures. These steps form the backbone of any high-standard research operation.

    Some colleagues run sample batches before diving into major projects, checking for solubility, flow, and response in their particular protocols. Those extra steps may seem slow, but they often save weeks of troubleshooting. If you’re planning a scale-up, make sure your supplier has a track record with larger batch sizes. Shortages and bottlenecks can derail even the best idea, so keeping a close relationship with trusted sources makes practical, everyday sense.

    Product Evolution: Where Does 5,6-Dihydroxyindole Go Next?

    New chemical routes, purer outputs, and environmentally friendlier options already shape the market for this compound. I keep an eye out for suppliers investing in continuous-flow synthesis or plant-derived feedstocks. These innovations don’t just help the planet—they secure the future for labs, clinics, and manufacturers that need steady access to high-quality raw materials.

    Cross-disciplinary work offers fresh opportunities. Teams blending chemistry, engineering, and biology are pushing 5,6-Dihydroxyindole into spaces far beyond pigment science. Antioxidant therapies, smart packaging, even wearable sensor technology—this molecule has emerged as a go-to starting point thanks to its unique mix of reactivity and manageability.

    From Research to Real Life: Respecting the Roots

    In a world full of high-tech promises and buzzwords, sometimes the old standbys offer more than meets the eye. 5,6-Dihydroxyindole reminds me that real progress often builds on careful work with dependable ingredients. Every new generation of scientists, product developers, and engineers finds fresh ways to use this compound, turning basic building blocks into the breakthroughs of tomorrow.

    Tracking its growth across pigment research, diagnostics, advanced materials, and biotechnology, it’s clear that 5,6-Dihydroxyindole has proven itself time and again. The molecule stands as a bridge between nature’s chemistry and human curiosity—a reminder that small, stable compounds can spark big changes. And for those willing to put in the effort—through careful sourcing, mindful storage, and creative experimentation—the benefits stretch far beyond the confines of the lab.