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HS Code |
525386 |
| Chemical Name | 2-(4-Chlorophenyl)hexanenitrile |
| Molecular Formula | C12H14ClN |
| Molecular Weight | 207.70 g/mol |
| Cas Number | 57482-51-2 |
| Appearance | White to off-white solid |
| Solubility | Soluble in organic solvents such as ethanol and DMSO |
| Smiles | CCCC(C#N)C1=CC=C(C=C1)Cl |
| Inchi Key | YZTZXTXEPZQRDG-UHFFFAOYSA-N |
| Storage Conditions | Store in a cool, dry, well-ventilated place |
| Purity | Typically >98% |
As an accredited 2-(4-Chlorophenyl)Hexanenitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 25 grams of 2-(4-Chlorophenyl)hexanenitrile, securely sealed with a tamper-evident cap and hazard labeling. |
| Shipping | 2-(4-Chlorophenyl)hexanenitrile is shipped in tightly sealed containers, protected from moisture and light, and stored at room temperature. Proper labeling and documentation are provided, complying with relevant hazardous material regulations. Shipments typically use sturdy packaging materials to prevent breakage or leakage during transit, ensuring safe handling and delivery to the recipient. |
| Storage | 2-(4-Chlorophenyl)hexanenitrile should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizing agents. Protect from light and moisture. Proper chemical labeling is essential, and access should be restricted to trained personnel. Store in accordance with local regulations for hazardous chemicals. |
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Purity 98%: 2-(4-Chlorophenyl)Hexanenitrile with 98% purity is used in pharmaceutical intermediate synthesis, where it ensures high reaction yields. Melting point 52°C: 2-(4-Chlorophenyl)Hexanenitrile with a melting point of 52°C is used in fine chemical manufacturing, where it provides predictable solid-state handling. Molecular weight 223.72 g/mol: 2-(4-Chlorophenyl)Hexanenitrile with a molecular weight of 223.72 g/mol is used in agrochemical precursor formulation, where it achieves precise formulation accuracy. Stability temperature 120°C: 2-(4-Chlorophenyl)Hexanenitrile stable up to 120°C is used in catalytic process development, where it maintains compound integrity under heat. Particle size <50 μm: 2-(4-Chlorophenyl)Hexanenitrile with particle size below 50 μm is used in custom reagent blending, where it enables uniform dispersion. Moisture content <0.2%: 2-(4-Chlorophenyl)Hexanenitrile with less than 0.2% moisture content is used in sensitive organic syntheses, where it prevents side reactions. Color index ≤10 (APHA): 2-(4-Chlorophenyl)Hexanenitrile with color index below 10 APHA is used in dye intermediate production, where it ensures color consistency. Solubility in DMSO >20 mg/mL: 2-(4-Chlorophenyl)Hexanenitrile soluble in DMSO above 20 mg/mL is used in bioassay screening, where it ensures homogeneous dosing. |
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Chemistry shapes how people experience everything from health care to advanced technology. Synthetic chemicals like 2-(4-Chlorophenyl)Hexanenitrile often don’t get much attention from outside the industry, but their true value shows up far beyond the laboratory. With its unique structure — a six-carbon chain attached to a chlorinated phenyl group, capped with a nitrile — this molecule produces reactions that bring major benefits to both manufacturing and research. I’ve spent time in a lab where choosing a precise chemical determines whether a project works. Little choices like using a slightly longer carbon chain can shift a reaction yield, purity, or even the color of the final crystal. That’s where this compound’s steady profile really comes through.
2-(4-Chlorophenyl)Hexanenitrile comes with carefully defined specifications. With a formula of C12H14ClN, the product stands out for its purity, controlled melting point range, and optimized particle size distribution. During my own hands-on years in organic synthesis, I found the need for steady, reproducible reagents could make or break a week’s worth of effort. This compound’s stability — especially under standard storage — lets research groups push their work forward without pausing for breakdown products or unexpected contaminants.
When making specialty intermediates or focusing on subtle electronic effects, minor tweaks around the phenyl ring, such as chlorine at the para position, shift reactivity just enough to open new routes that simple benzonitriles can’t offer. The longer hexanenitrile tail also offers solubility advantages compared to shorter chains, making it useful in systems where both oily and polar phases interact.
Every laboratory faces choices when picking building blocks — it’s rarely about finding the only suitable compound. More about matching the right features to real needs. Compared to other nitriles, 2-(4-Chlorophenyl)Hexanenitrile resists hydrolysis and oxidation, which helps users store it comfortably over months, not just days. I’ve watched older batches pulled from shelves only to discover degradation — a costly setback in both research budgets and momentum.
What really differentiates this molecule is its combination of lipophilicity, a moderately bulky side chain, and that well-placed chlorine atom. Subtle features like these let research chemists tune physical properties or target specific receptor sites in pharmaceuticals. In exploring custom syntheses, I’ve bumped up against solubility walls, and longer chains often rescue stalled efforts. 2-(4-Chlorophenyl)Hexanenitrile slides easily between phases, which has sped up separations — an often overlooked benefit.
In the broad market of chemical intermediates, plenty of compounds overlap in use. Yet not every product combines reliable assay results, shelf stability, and a track record in both pharmaceutical and agrochemical applications. My own time working with generic benzonitriles left me impressed by that extra length in the carbon chain — it opened up easier workup steps, sometimes displacing need for extra solvents.
Everyone in the chemicals business runs up against multifaceted projects. While no compound works in every scenario, I’ve watched 2-(4-Chlorophenyl)Hexanenitrile succeed in several diverse fields thanks to its adaptability. In fine chemicals production, it often serves as a key starting point or intermediate, especially in projects requiring later transformations — such as amination, alkylation, or addition reactions. In medicinal chemistry, its unique profile helps craft compounds geared toward binding to receptors where both hydrophobic and halogen bonding play a role. For researchers needing to maintain integrity through several synthetic steps, this molecule’s resistance to harsh conditions has a proven upside.
Turning to process chemistry, I’ve dealt with scale-up attempts that fizzled because the chosen nitrile simply didn’t dissolve well, or produced troublesome emulsions. The longer carbon tail in 2-(4-Chlorophenyl)Hexanenitrile offers process engineers flexibility — it helped avoid phase transfer headaches that crop up with shorter, less oily nitriles.
Having spent day after day pipetting, weighing, and purifying — the practical difference in picking the correct nitrile sometimes comes down to a sharper melting point, fewer side products, and easier handling. During time spent at the bench, I came to trust molecules like 2-(4-Chlorophenyl)Hexanenitrile for their reliability. Ease of measurement, crystal formation, and streamlined purification shave hours off routine work. Small labs especially benefit when they can trust reagents not to clog up glassware or leave behind sticky residues. The molecular design here aids both clean reactions and straightforward product isolation.
I remember one project where a similar nitrile failed to dissolve in either of the commonly used solvents, requiring days of tedious trial and error. Switching to a compound like 2-(4-Chlorophenyl)Hexanenitrile, with its balanced solubility, simply kept the project on track and kept faces smiling at meeting deadlines instead of grappling with stubborn residues.
Concerns over chemical safety and sustainability never take a day off. Researchers and companies today lean toward reagents that balance performance with storage and waste concerns. 2-(4-Chlorophenyl)Hexanenitrile’s stability makes a tangible contribution here — longer shelf life cuts down on wasted, expired product and reduces disposal needs. That simple benefit echoes across budgets and sustainability goals.
Having experienced strict audit conditions, I know how much time careful chemical management claims each week. Choosing products with lower risks of decomposition streamlines recordkeeping and waste handling. Fewer breakdown products also mean fewer unknowns turning up at later steps or in environmental tests. The push toward safer and more predictable intermediates aligns closely with how this compound behaves under real laboratory conditions.
One constant in chemical supply, from small startups to global manufacturers, revolves around dependability. Nobody wants a mystery batch to disrupt a process or risk product recalls. I’ve seen reactions creep off track due to off-spec solvents or reagents, turning what should have been a straightforward synthesis into a troubleshooting marathon. With this compound, routine lot-to-lot testing shows tight consistency in key parameters like melting point and purity.
Chemically, the package brings users dependable reactivity and controlled impurity profiles, reducing worries about hidden contaminants that could torpedo sensitive reactions. From conversations with development chemists, it’s clear many put their trust in products with recognizable histories of reproducibility and clear supporting data. That’s the difference between a “maybe it’ll work” and a “we can plan the rest of the project” experience.
Many research and manufacturing teams battle with cost overruns not from the main starting materials, but from countless adjustments, remakes, and delays that result from unreliable intermediates. In my work leading pilot syntheses, small differences — one lot seeming a bit “off” in flow or texture — can snowball into weeks of inefficiency. 2-(4-Chlorophenyl)Hexanenitrile’s predictability means fewer midstream surprises. Teams get to focus on their product, not troubleshooting their supply chain.
There’s a direct line between this chemical’s reactivity profile and the ability to finish complex syntheses on time. Fewer side reactions, cleaner conversion, and easier downstream handling lead to fewer headaches. I’ve seen cycles of “fixing” poor intermediates consume days — using reliable product in the first place keeps projects on course and brings genuine value to small organizations trying to compete or scale up.
Each year brings more choices in specialty chemicals. Selection often feels overwhelming for newer chemists or procurement teams. What actually makes a difference? From experience, it’s often a combination of how a product behaves in simple lab tests and how it fits into a larger workflow. Features like easy storage, steady assay performance, and well-defined physical properties tend to matter much more than flashy marketing claims.
For those synthesizing active pharmaceutical ingredients or custom specialty products, 2-(4-Chlorophenyl)Hexanenitrile offers a rare mix of flexibility and security. Its physical properties suit multiple solvent systems — I’ve run extractions where most alternatives simply floated or refused to mix, but this compound found its phase and moved forward cleanly. That saves both time and solvent, shrinking process costs in a real, measurable way.
Deciding whether to use this specific compound or a near neighbor depends on downstream plans. If a project calls for stability in storage, compatibility with both polar and non-polar phases, and smooth handling in purification, this one stands up well to scrutiny. I’ve attended meetings where a switch to an alternative meant revalidating steps, extending project timelines needlessly. A dependable, proven choice often means more than any savings from cheaper but unpredictable materials.
Engagement across the chemical community — trading experiences about which intermediates cut down on workups or aid in cleaner chromatographic separations — always seems to turn up repeated mentions of 2-(4-Chlorophenyl)Hexanenitrile. Anecdotes from the bench align with data sheets in this case. Researchers praise fewer side-products, better batch recovery rates, and a noticeable reduction in failed runs.
Test runs sometimes go sideways even with skilled teams at the helm. My time in both research and scale-up has taught me to plan for chemical unpredictability and seek out materials with a record for not making trouble. That means using intermediates with low levels of residual moisture, stable chemical profiles, and a reputation for supporting both routine and demanding projects.
One example comes from a failed multi-step synthesis. After two purification steps, the process kept stalling out with unexpected colored impurities. By switching the intermediate to an option with fewer unknown byproducts — specifically, moving to 2-(4-Chlorophenyl)Hexanenitrile — the workflow cleared. Sometimes, less glamorous decisions, like picking the slightly longer nitrile, end up supporting the flashy breakthroughs down the road.
Intellectual property and novel patents rest on creative synthetic designs. Many breakthroughs sprout from small tweaks to familiar molecules. For patent attorneys and R&D managers, an intermediate with both unique structure and versatile reactivity can support dozens of invention claims. From what I’ve seen, this compound’s substituted aromatic ring and longer aliphatic tail slot perfectly into “new-molecule-space,” letting development teams branch out faster than generic lab standards.
A few successful innovations in recent years cite the use of 2-(4-Chlorophenyl)Hexanenitrile as a core intermediate for new families of drug candidates and advanced agrichemicals. Those projects relied on its manageable physical form, reliable stoichiometry, and ease of adaptation to different synthetic plans.
After years working both at the bench and in project planning, I’ve found real-world needs drive better chemical innovation than any theoretical “one size fits all” dreams. Chemists tend to vote with their feet, returning again and again to reagents that make progress smoother, batches safer, and costs easier to predict. Getting hands-on with 2-(4-Chlorophenyl)Hexanenitrile has shown me it ticks boxes both for creative research and for routine production demands.
An intermediate that spans such a range — helping both custom synthesis and scaling up specialty output — brings measurable value. Safety, reliability, straightforward handling, and predictable reactivity let users lower their mental load and focus on the work that matters most. From larger pharmaceutical companies to small contract labs, the word-of-mouth reputation matches the data: this product offers a steady hand in situations where others often stumble.
Chemical development keeps accelerating, pushed by client needs and regulatory shifts. At every level, from research to manufacturing and supply chain, partners want assurance that today’s choices won’t turn into tomorrow’s headaches. Products that balance robust performance, chemical stability, and broad compatibility — tangible features on the lab benchtop — carry extra weight.
I’ve watched the shape of research evolve, with new priorities around cleaner processes, less hazardous waste, and rapid innovation. Products like 2-(4-Chlorophenyl)Hexanenitrile give teams options while meeting practical demands. This compound’s story grows every time teams report easier workups, more robust yields, or completed projects with fewer delays. It stands as an example of why choosing the right building block is more than just ticking off a material from a procurement list — it’s choosing smoother progress, less waste, and more room for creative breakthroughs.
Part of smart chemistry today involves long-term thinking about safety and environmental responsibility. With every batch planned, the best teams ask whether current choices support progress — not just for the bottom line, but for health, safety, and future sustainability. From what I’ve handled, 2-(4-Chlorophenyl)Hexanenitrile meets those marks: it stores securely with fewer risks, supports predictable reactions, and limits extra disposal.
Across the evolving research landscape, intermediates like this tend to earn repeat business not because they’re new, but because they have proven themselves where it counts — on the bench, in production, and across long-term research partnerships. As the conversation in chemistry shifts toward shared value and ongoing improvement, these are exactly the kinds of compounds that will keep making the biggest impact.