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Zinc Citrate Dihydrate

    • Product Name Zinc Citrate Dihydrate
    • Alias Zinc citrate, dihydrate
    • Einecs 237-553-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    369648

    Productname Zinc Citrate Dihydrate
    Chemicalformula Zn3(C6H5O7)2·2H2O
    Molarmass 574.25 g/mol
    Appearance White to off-white powder
    Solubilityinwater Slightly soluble
    Zinccontent Approximately 31%
    Phvalue 5.0 - 7.0 (1% solution)
    Meltingpoint Decomposes before melting
    Casnumber 14221-02-4
    Odor Odorless
    Storageconditions Store in a cool, dry place
    Taste Slightly astringent
    Usage Dietary supplements, toothpaste, pharmaceuticals

    As an accredited Zinc Citrate Dihydrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White high-density polyethylene (HDPE) drum, securely sealed, labeled "Zinc Citrate Dihydrate, 25 kg," with batch and safety information.
    Shipping Zinc Citrate Dihydrate is shipped in sealed, moisture-resistant containers to prevent contamination and maintain product integrity. Typically packed in fiber drums or HDPE bags, it is labeled according to regulatory standards. Transport is conducted under cool, dry conditions, avoiding direct sunlight and incompatible substances to ensure safe delivery.
    Storage Zinc Citrate Dihydrate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong acids and bases. Avoid exposure to moisture and direct sunlight. Keep the storage area clean and clearly labeled. Follow all relevant safety guidelines and regulations for chemical storage to ensure safety and product stability.
    Application of Zinc Citrate Dihydrate

    Applications of Zinc Citrate Dihydrate in Industrial Manufacturing

    As the original producer of Zinc Citrate Dihydrate, we supply this multifunctional ingredient for formulation use in rigorously regulated downstream sectors. Our experience with raw material integration allows us to deliver consistent quality for customers whose end products require precise zinc supplementation and meet demanding safety and performance standards. Below, we detail real-world industry applications reflecting current regulatory and technological benchmarks.

    1. Oral Care Formulations

    Leading oral care manufacturers incorporate our zinc compound for its established role in controlling calculus accumulation and supporting anti-microbial action in toothpaste and mouth rinses. Laboratories select this ingredient due to its compatibility with fluoride systems and low reactivity, simplifying QC validation. In this segment, dental formula developers optimize usage ratios to meet regional anti-plaque and whitening claims while passing in-market challenge tests for stability and bioavailability.

    Industry compliance standards

    • ISO 16128 (Natural Extracts and Ingredients for Cosmetics)
    • U.S. FDA 21 CFR 355 (Anticaries Drug Products for OTC Human Use)
    • EU Cosmetics Regulation (EC) No. 1223/2009
    • China National Standard GB 22115-2019 (Toothpastes)

    Typical usage ratio

    • 0.5–1.0% w/w in toothpaste; 0.2–0.5% w/w in mouthwash, adjusted based on zinc ion contribution and target antimicrobial/biofilm reduction outcomes

    Downstream process integration

    • Introduced during batching after main aqueous phase, co-dispersed with abrasives, pre-dissolved for mouthwash blending, or added post-homogenization to control ion availability

    Final product types

    • Anti-plaque toothpaste
    • Whitening toothpaste
    • Mouth rinses for halitosis control
    • Desensitizing toothcare gels

    2. Food & Beverage Fortification

    In functional food and beverage enrichment, manufacturers utilize our material as a bioavailable zinc source approved for nutritionally targeted applications including dairy, processed foods, and sports hydration products. Technical teams prefer this form for its low solubility profile, which minimizes precipitation and taste interference in complex food matrices. Strict adherence to fortification limits and homogeneity in mass production lines are essential for industry acceptance.

    Industry compliance standards

    • Codex Alimentarius Standard 192-1995 (Food Additive List)
    • EU Regulation (EC) No 1333/2008 (Food Additives)
    • GB 2760-2014 (Chinese Food Additive Use Standard)
    • 21 CFR 182 (Generally Recognized as Safe Substances, FDA)

    Typical usage ratio

    • 5–15 mg elemental zinc/kg finished product, calculated per intended daily allowance and local regulatory limits for fortification; exact dosage fine-tuned based on specific food category

    Downstream process integration

    • Dry blending into premixes for cereal and beverage powders; incorporation at the liquid blending stage for UHT or pasteurized dairy products; added post-cooking in snack and supplement applications to retain micronutrient value

    Final product types

    • Fortified milk drinks
    • Breakfast cereals and bars
    • Electrolyte beverages
    • Nutritional supplement tablets and gummies

    3. Dietary Supplement Manufacturing

    Custom contract supplement producers source our zinc citrate dihydrate to meet label claims for immune health, bone metabolism, and metabolic support. The material’s stable dihydrate form assists tableting operations due to controlled water activity and predictable compression characteristics. For multi-component nutraceuticals, its citrate ligand provides synergy without excessive excipient needs, enabling efficient high-speed granulation.

    Industry compliance standards

    • USP-NF Monograph (United States Pharmacopeia–National Formulary)
    • EU Directive 2002/46/EC (Food Supplements)
    • ISO 22000 (Food Safety Management)
    • China GB 31601-2015 (Health Foods GMP)

    Typical usage ratio

    • 10–30 mg elemental zinc per daily dose, formulated according to regional health authority guidelines and specific supplement market claims

    Downstream process integration

    • Pre-mixed into direct compression blend for tablets; wet granulated for powder-filled capsules; dispersed in liquid suspensions with flavoring and stabilizers for liquid dietary supplements

    Final product types

    • Zinc tablets and capsules
    • Pediatric suspensions
    • Effervescent powders/granules
    • Chewable multivitamin tablets

    4. Veterinary Nutrition Blends

    The animal feed and pet nutrition segment applies this functional ingredient as an authorized trace mineral, valued for its gentle gastric impact in companion animal formulations and precise dosing in performance livestock blends. Feed integration demands consistent particle size and dust control to maintain batch consistency and comply with micronutrient fortification programs verified by animal nutrition specialists.

    Industry compliance standards

    • AAFCO Official Publication (U.S. Association of American Feed Control Officials)
    • EU Regulation (EC) No 1831/2003 (Feed Additives)
    • China GB 7300.402-2005 (Feed Additive Zinc Compounds Standard)
    • FAMI-QS (Feed Additive and Premixtures Quality System)

    Typical usage ratio

    • 50–120 mg elemental zinc/kg feed for poultry and swine; 40–80 mg/kg for pet food, with dosage defined by species and phase of growth as recommended by nutrition research

    Downstream process integration

    • Micro-mixing into vitamin-mineral premixes before full batch blending; introduced post-extrusion for sensitive pet food formulas; diluted prior to spray-drying of specialty feeds

    Final product types

    • Dog and cat dry kibbles
    • Livestock compound feed (poultry, swine)
    • Aquaculture premixes
    • Fortified animal snacks and supplements

    5. Functional Coating Agents for Medical Devices

    Producers of advanced wound dressings and antimicrobial medical device coatings employ our zinc salt for ion-release matrices and film-forming solutions. The dihydrate’s controlled solubility facilitates predictable zinc delivery over extended usage periods, and complies with critical purity and leachable residue thresholds, making it suitable for direct contact with tissue or mucosa.

    Industry compliance standards

    • ISO 10993-1 (Biological Evaluation of Medical Devices)
    • USP <661> (Plastic Packaging Materials)
    • EU MDR 2017/745 (Medical Device Regulation)
    • 21 CFR 820 (FDA Quality System Regulation)

    Typical usage ratio

    • 0.1–0.6% w/w in hydrogel or polymer solution, set based on desired zinc ion release kinetics and total surface area in antimicrobial dressings or coatings

    Downstream process integration

    • Dispersed in aqueous film-forming bases prior to application on mesh, foam, or hydrocolloid substrates; alternatively, blended into resin before extrusion or sprayed onto sterile substrates under cleanroom conditions

    Final product types

    • Chronic wound care dressings
    • Catheter and tracheal tube antimicrobial coatings
    • Absorbent hemostatic pads
    • Moisture control barrier films

    6. Water Treatment and Purification Media

    In the water purification sector, manufacturers leverage our zinc compound for formulating slow-release antimicrobial ceramics and filter media to address microbial contamination in point-of-use and municipal systems. Comprehensive QC screening ensures alignment with standards for potable water applications, while zinc loading targets depend on expected flow rates and contamination levels in service environments.

    Industry compliance standards

    • NSF/ANSI 61 (Drinking Water System Components – Health Effects)
    • EN 13443-1 (Water Conditioning Equipment)
    • EPA Safe Drinking Water Act
    • China CJ/T 206-2005 (Domestic Drinking Water Purification Materials)

    Typical usage ratio

    • 0.1–1.0% w/w for ceramic filter beds; actual load varies by calculated release rate and system lifetime

    Downstream process integration

    • Incorporated into ceramic clay prior to firing or sintering; co-precipitated with carriers during filter block manufacturing; added to media blends before molding and extrusion

    Final product types

    • Household water filter cartridges
    • Commercial point-of-entry water systems
    • Municipal disinfection media
    • Portable water purification devices
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    Certification & Compliance
    More Introduction

    Zinc Citrate Dihydrate: Our Experience and Insights on a Trusted Zinc Compound

    Understanding Zinc Citrate Dihydrate in Daily Manufacturing

    In our years of work as a chemical manufacturer, we’ve learned that not all zinc compounds behave the same—especially when you push them through tough production cycles or add them to complex formulations. Zinc Citrate Dihydrate (model: ZCDH-2088) stands out in many workshops because it combines the crucial element of zinc with the stability of citric acid, finished off with two water molecules. We keep the active zinc content between 30.0% and 31.0%, and check moisture is less than 11%. This isn’t just numbers on a spec sheet. It plays out every day on our shop floor, where steadiness in composition saves both ingredients and troubleshooting time.

    When we switched some of our early batch processes from zinc sulfate to zinc citrate dihydrate, the difference instantly hit the production line. Zinc Citrate Dihydrate holds its shape, appearing as a fine, white powder without the caking or odd color changes we used to see from more reactive salts. This matters for tablet and capsule pressing—clumping or variable color would mess up whole batches. No one wants costly downtime or customer complaints about product appearance. In toothpaste and mouthwash runs, the compound holds steady, and the mild citrate base keeps the flavor neutral. Our technical crew tells us the solubility sits just right for even dispersion, especially in water-based blends and oral health items.

    Why Formulators Stick with Zinc Citrate Dihydrate

    People in the lab and production line often ask why we keep zinc citrate dihydrate as a staple. Zinc is, of course, necessary in human health: enzymes, immune system maintenance, and as a trace element in skin and oral care. Yet the form it takes changes everything. Some forms of zinc break down too quickly, lead to metallic tastes, or don’t last across the shelf life of toothpaste and supplements. Zinc acetate, for example, gives more solubility but tastes harsh and splits faster in humid warehouses. Zinc oxide can be chalky and gritty, a pain to blend, and brings opacity you just can’t hide in clear drinks or supplements.

    Our zinc citrate dihydrate keeps a firm balance. It’s not too soluble, which keeps shelf life strong, but it also offers enough zinc release to make nutritionists and dental researchers happy. It helps bind tartar in dental rinses, inhibits bacterial growth in mouth and gum items, and keeps mineral supplements stable as regulations grow tighter on impurity thresholds. In our case, finished products using our zinc citrate dihydrate consistently test safe on lead, cadmium, and arsenic—well below the max allowed for food and pharma markets. We don’t just rely on in-house checks. We’ve sent samples through independent labs in Europe and East Asia, and the numbers hold up across the board.

    Hands-On Production Insights

    Chemists and operators working with zinc citrate dihydrate report manageable dusting, a problem that plagues some lightweight zinc salts. Our workers say the powder flows evenly from bin to feeder, a relief when you’ve handled sticky or lumpy materials. Equipment doesn’t gum up during blending. We’ve tested press runs for over eight hours straight, and the compound never heats up or clumps, even under shifts where humidity spikes after rain. For liquid formulations, the dihydrate dissolves with gentle agitation, leaving little residue at the bottom of tanks.

    We know real-world production throws curveballs. Some clients want fine granules, others prefer powder. Our experience shows the 80–100 mesh powder settles right into tableting and capsule lines, and in beverage fortification, there’s no visible precipitation even after standing 24 hours. This means beverage manufacturers don’t have to re-run batches or worry about customer complaints over “floaters” and sediment.

    Comparing Zinc Citrate Dihydrate with Other Zinc Compounds

    Our team often fields questions about why zinc citrate dihydrate should be favored over more typical forms like zinc oxide or zinc gluconate. Here’s what our production runs and R&D trials reveal. Zinc oxide remains common for low-cost enrichment in animal feeds or sunscreens, but it resists dissolution in neutral pH systems and adds graininess. Zinc acetate breaks down too quickly, so it’s less stable under shelf stress, especially in warm climates. Zinc gluconate has won favor in cold remedies but brings a tangy taste in food and drink and costs a good deal more per ton.

    Zinc citrate dihydrate brings milder taste and enough solubility to deliver zinc uptake without shocking sensitive taste buds. Consumer brands have responded—our batches end up in popular toothpaste lines sold throughout North America, Europe, and the Middle East. We’ve seen beverage and nutraceutical firms switch over for the milder flavor and reduced sedimentation. The dihydrate structure also resists agglomeration in long-term warehouse storage, so our partners report fewer rejections from moisture pickup or compaction.

    Quality and Consistency from Factory Floor to Finished Product

    We take pride that every ton of zinc citrate dihydrate leaves our factory tested for heavy metals, purity, moisture, and zinc content—checked at multiple production points. We have designed our processes to minimize batch-to-batch swings. Our technicians track the drying phase and intervene early if moisture shows any sign of drifting above our limit, because excessive moisture creates hazards in high-speed tablet pressing and can introduce clumping. Each operator on the line is trained to spot visual or textural changes. We run periodic deep analysis on retention samples from every large batch, since hindsight often reveals long-term stability issues that short-term testing can miss.

    The need for predictable particle size and powder flow isn’t just technical jargon—it touches every producer from pharmaceuticals to fortified drinks. When particle size drifts too fine, airborne dust can cause health hazards and loss of raw material. Oversized particles create uneven zinc dispersion in the final formulation. Over decades of manufacturing, we have revised our grinding and drying steps to keep the product safely in the 80–100 mesh band, balancing easy mixing with minimal dust.

    Regulatory Compliance and Food Safety: What Matters in Zinc Citrate

    Whether our customers operate under USP, FCC, or E 333 monographs, regulatory scrutiny shapes every batch we make. We see rising global concern over contaminants in food and dietary supplements—lead, cadmium, arsenic, and mercury fall under stricter limits year after year. Our zinc citrate dihydrate, crafted from primary-grade citric acid and refined zinc, repeatedly passes these tests. Third-party audit programs regularly inspect not just raw materials but also sanitation protocols, staff training, pest control, and document traceability. When cross-checked against monograph standards, even batches destined for infant food-grade application make the cut without reformulation.

    In factories where we handle both animal feed and food-grade ingredients, strict clean-out procedures separate batches and minimize cross-contamination risks. We deploy real-time sensors for humidity and temperature to stop decay at the source. It’s a running discussion with our purchasing team to source citric acid and zinc sources with the lowest trace heavy metals, so that our final product doesn’t pick up unnecessary load downstream.

    Application Experience: From Powder to End Use

    In dental care, zinc citrate dihydrate shows up in products promising tartar protection and fresher breath. The zinc ion inhibits the metabolism of oral bacteria which produce sulphur compounds responsible for bad breath. Lab partners have shown that this inhibition works at low parts-per-million concentrations, meaning formulators don’t need to overload the toothpaste. The citric acid backbone further aids in gentle binding to tartar, providing an additional mode of action compared to raw zinc oxide.

    The story is similar in dietary supplements. Our production partners indicate that zinc citrate dihydrate presents fewer taste challenges than zinc sulfate or acetate when pressed into chewable tablets or dissolved into syrups. The mild flavor lets them design consumer-facing products children will actually swallow—without disguising zinc behind sugar loads or masking flavors. This same favorable profile supports beverage fortification, where subtle flavors matter and product appearance can make or break a brand’s image.

    Nutritional researchers working with our product conducted double-blind trials in fortified beverages and snacks. Zinc citrate dihydrate maintained bioavailability—absorption levels similar to more soluble forms—while subjects reported little to no metallic aftertaste. We’ve seen this echoed in clinical results across several years. In powder blends used for hospital nutrition or sports rehydration, there’s a reduction in caking and improved reconstitution, especially when the powder sits on the shelf for months.

    Handling and Storage: Practical Lessons Learned

    On the factory side, our storage team pays special attention to humidity control when handling zinc citrate dihydrate. Dihydrate forms bind water—too much external moisture, and you risk clumps and spoilage. Too little, and the powder becomes airborne, causing handling losses and occasional irritation. We store finished bags in cool, shaded environments, and avoid stacking pallets too high to prevent caking at the bottom. Teams receive monthly training sessions on safe handling, since proper gloves and masks make a difference when loading or blending.

    Customers who experienced shipment delays in rainy seasons reported intact quality after months of storage, provided the warehouse environment remained dry and the packaging sealed. Smaller packaging sizes also reduce the time bags remain open, cutting the risk of moisture pickup. We design our packaging for high resistance to tears and puncture, following plenty of stories where generic multilayer bags failed and let in moisture on long freight journeys. On return visits to clients, we check warehouse practices and suggest improvements if we notice any mistakes—one forgotten open bag or a broken pallet can undo months of careful manufacturing.

    Environmental and Sustainability Considerations

    There’s always a question about the environmental footprint of mineral compounds. We’ve put effort into streamlining wastewater management and reducing dust emissions at our production site. Modern filter systems reclaim airborne powder, shrinking material loss and lowering the total release into the environment. Our zinc sources come from refined supply chains, avoiding recycled scrap zinc that might introduce impurities, a lesson we picked up after finding unpredictable heavy metal loads in poorly sourced material.

    Our waste management plan ensures run-off water meets discharge standards before leaving the facility. Any mother liquor from production cycles is reprocessed to recover as much zinc content as possible, reducing unnecessary disposal. We’ve partnered with local agencies to check soil and water for zinc traces, posting results on our site for customer review. In recent years, growing customer preference for responsible sourcing has made it clear—we must track not only product quality but also the legacy our process leaves behind.

    Challenges and Solutions in Zinc Citrate Dihydrate Manufacturing

    One challenge we meet is maintaining a stable product moisture level while processing thousands of kilos each day. Dihydrate, by definition, holds water; stripping too much leads to anhydrous material, which may clump and give differences in zinc content during further processing. Leaving too much moisture leads to caking, instability, and difficulty during pressing or blending. Our production shift leaders regularly pause runs to manually check moisture content and cross-verify against laboratory values. We invested in calibrated online sensors to get real-time readings, saving both time and loss.

    Another persistent issue comes up during the grinding and sieving stage. Blades warm up and can dry product unintentionally, shifting moisture down and affecting the dihydrate state. To tweak this, we run shorter grinding cycles with cooling pauses, rather than driving the entire lot through at full speed. Repairs and blade replacements are scheduled frequently, since blade shape influences final powder size and behavior. Operators in the control room can override the conveyor if dust levels climb beyond a set point, avoiding redistribution of zinc powder into other production areas.

    Transporting zinc citrate dihydrate seems simple, but bulk shipping raises the risk of humidity spikes or crushing under heavy pallet load. We respond by reinforcing pack corners and loading trucks only after kilometer-long journeys are confirmed dry and dust free. Overseas orders, especially those facing weeks at sea, get double-walled bags and inner liners following client audits.

    Final Thoughts from the Production Line

    Zinc citrate dihydrate proves itself each day through reliable performance in complex blends, consistent physical appearance, and compliance across multiple regulations. It’s earned its place in dental, food, and nutritional applications not just by meeting a list of technical boxes, but by standing up to all-season production, customer audits, sudden regulatory shifts, and the daily scrutiny from people who run these lines by hand and eye. Across thousands of tons over years, it keeps showing a unique mix of mineral stability and practical user-friendliness in real-world settings.

    We keep pushing to refine manufacturing methods and raw material tracking so customers get not just a commodity, but a compound they can trust in every batch. Zinc citrate dihydrate rewards the focus on process consistency, careful storage, and reliable shipping. Each improvement in this process reflects practical lessons earned from time spent on the production floor, review desk, and in customer warehouses worldwide. The product continues to evolve with industry needs, setting a standard for mineral fortification and oral care solutions going forward.