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Z-Orn-OH

    • Product Name Z-Orn-OH
    • Alias Z-Orn(2-ClZ)-OH
    • Einecs 239-254-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    176995

    Chemical Name N-alpha-benzyloxycarbonyl-L-ornithine
    Abbreviation Z-Orn-OH
    Molecular Formula C13H18N2O4
    Molecular Weight 266.29 g/mol
    Appearance white to off-white powder
    Solubility soluble in water, methanol, and DMF
    Melting Point 150-155°C
    Cas Number 1466-36-6
    Purity typically ≥98%
    Usage peptide synthesis
    Protecting Group benzyloxycarbonyl (Z)
    Optical Activity [α]20/D +18° (c=1, H2O)
    Storage Temperature 2-8°C
    Synonyms Cbz-L-Ornithine, Z-L-Ornithine

    As an accredited Z-Orn-OH factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Z-Orn-OH is supplied in a clear, sealed glass vial containing 1 gram of white powder, labeled with product and safety details.
    Shipping Z-Orn-OH is shipped in a tightly sealed container, protected from light and moisture. It is packaged according to standard chemical safety regulations, with appropriate labeling and documentation. The shipment complies with air and ground transport regulations for non-hazardous chemicals, ensuring stability and prevention of contamination during transit.
    Storage Z-Orn-OH should be stored in a tightly sealed container, protected from light and moisture. Keep at a temperature of -20°C to maintain stability and prevent degradation. Store in a well-ventilated, dry, and cool area, away from incompatible substances. Always follow proper laboratory safety protocols and consult the product’s safety data sheet for specific storage recommendations.
    Application of Z-Orn-OH

    Applications of Z-Orn-OH in Industrial Manufacturing

    Z-Orn-OH, as a high-purity ornithine derivative, contributes specialized functional performance across tightly regulated industrial segments. Our advanced production and stringent quality management ensure suitability for integration in each key downstream application sector, with traceability and documentation supporting regulatory and customer audits.

    1. Clinical Nutrition & Parenteral Solutions

    Healthcare manufacturers integrate Z-Orn-OH in amino acid blends used for infusion therapy and clinical nutrition. Facilities require materials meeting tight impurity profiles and consistent batch reproducibility. Its role as a metabolic intermediate supports nitrogen balance management for vulnerable patient populations, demanding strict regulatory and compositional control throughout solution compounding and lyophilization steps.

    Industry compliance standards

    • USP–NF/EP Pharmacopoeia Grade requirements
    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • FDA 21 CFR Part 210/211 (U.S. cGMP for finished pharmaceuticals)
    • Japanese Pharmacopeia standards for injectable composition

    Typical usage ratio

    • 0.05–0.5% w/v in amino acid parenteral mixtures, adjusted based on patient clinical protocols and total nitrogen requirements

    Downstream process integration

    • Add during aqueous solution blending under sterile conditions; proceeds to sterile filtration, aseptic filling, and lyophilization or liquid packaging

    Final product types

    • Amino acid injection solutions
    • Total Parenteral Nutrition (TPN) bags
    • Intravenous amino acid supplements for clinical use

    2. Peptide Synthesis Reagents

    Contract peptide manufacturers use Z-Orn-OH as a protected amino acid building block in solid-phase peptide synthesis (SPPS). It enables custom peptide sequences with ornithine moieties, supporting rapid scale-up and quality control in drug discovery, diagnostics, and research. Strict monitoring of precursor and byproduct profiles ensures downstream peptide release meets purity and identity requirements.

    Industry compliance standards

    • ISO 9001:2015 quality systems
    • European REACH chemical registration for laboratory intermediates
    • ICH Q3A/B Guidelines (Impurities in New Drug Substances & Products)
    • Custom client specifications for peptide purity

    Typical usage ratio

    • 1 equivalent per ornithine unit in peptide sequence, with minor excess (1.0–1.2 equivalents) to drive complete coupling

    Downstream process integration

    • Load onto solid support resin after Fmoc deprotection; proceeds through iterative coupling cycles, then global cleavage and purification

    Final product types

    • Research-grade peptides
    • Therapeutic oligopeptides
    • Peptide antigens and custom diagnostic peptides

    3. Biotechnological Fermentation Media

    Industrial fermentation operators rely on Z-Orn-OH as a nitrogen and carbon source to optimize microbial expression systems, notably in recombinant protein and enzyme production. Its well-defined impurity profile helps support consistent cell growth, protein folding, and metabolic activity under large-scale cGMP fermentation, with continuous monitoring for batch-to-batch reproducibility and contamination avoidance.

    Industry compliance standards

    • ISO 13485 for medical biotechnology manufacturing
    • GMP regulations for fermentation media in biopharmaceuticals (e.g., EudraLex Vol. 4 Part I)
    • FDA 21 CFR 211 for quality in biotech APIs
    • Endotoxin and mycoplasma contamination controls

    Typical usage ratio

    • 0.02–0.1% (w/v) in complex or defined fermentation media; adjusted depending on microbial strain and target protein

    Downstream process integration

    • Dissolve into sterilized fermenters prior to inoculation; remains throughout fermentation, followed by product recovery and downstream purification

    Final product types

    • Recombinant therapeutic proteins
    • Industrial enzymes
    • Biosimilar active ingredients

    4. Specialty Nutraceutical Formulation

    Dietary supplement and nutraceutical firms use Z-Orn-OH for targeted amino acid blends that support sports nutrition and metabolic health products. Adherence to food safety protocols and label claim verification drives the need for traceable, documented raw material inputs, especially for export to markets with stringent ingredient regulations. Nutraceutical tablets and capsules require tested bioavailability and stability throughout shelf life.

    Industry compliance standards

    • FSMA (U.S. Food Safety Modernization Act)
    • EU Regulation (EC) No 852/2004 on the hygiene of foodstuffs
    • ISO 22000 food safety management
    • Local health authority registration for dietary supplements

    Typical usage ratio

    • 100–500 mg per serving in finished supplement; formulators adjust based on regional regulatory limits and evidence from human studies

    Downstream process integration

    • Blend into premix powders prior to granulation, tablet compression, or encapsulation, followed by stability testing and batch release

    Final product types

    • Amino acid tablets and capsules
    • Sports nutrition blends
    • Functional powder drink mixes

    5. Diagnostic Chemistry Kits

    Diagnostic reagent formulators leverage Z-Orn-OH for assay calibration and as a control component in enzyme- or antibody-based diagnostic kits. Reproducibility, trace impurities, and chemical stability undergo validation against analytical protocols, with mandatory compliance to in vitro diagnostic (IVD) regulations and third-party audits for manufacturing batch records and shelf-life claims.

    Industry compliance standards

    • IVD CE Marking (EU Directive 98/79/EC, transitioning to IVDR 2017/746)
    • ISO 13485:2016 for medical device quality management
    • FDA 21 CFR 820 (Quality System Regulation for medical devices)
    • CLSI (Clinical Laboratory Standards Institute) assay development standards

    Typical usage ratio

    • 0.1–1.0 mM in control and calibration solutions, tailored to the reference range of specific diagnostic target

    Downstream process integration

    • Combine in bulk calibration reagent preparation under ISO 7 cleanroom; aliquot and seal into kit vials, then validate stability and activity

    Final product types

    • Clinical chemistry assay kits
    • Point-of-care diagnostic panels
    • Calibration standards for laboratory analyzers
    Free Quote

    Competitive Z-Orn-OH prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Z-Orn-OH: Setting a New Standard for Modern Chemical Solutions

    Why Z-Orn-OH Takes Center Stage in Performance-Driven Industries

    Over the years, we’ve learned that chemical manufacturing is about getting the right solution into the hands of professionals who actually work with the stuff—on shop floors, in research labs, on production lines. Z-Orn-OH stands out in our product line because we've put our boots on the ground to really listen to our customers. This isn’t something that came from a boardroom wish-list; it's a response to the way work actually happens out there, from early-stage research labs to full-scale production plants.

    Z-Orn-OH began as a project to solve a recurring set of headaches for our long-term partners in advanced materials and specialty synthesis. Operators and technicians kept running up against reliability issues with older grades. Most alternatives would break down prematurely during thermal cycles, or they’d bring along too many trace contaminants. So, we went back to the fundamentals. Our development teams gathered data from dozens of plant runs, tracked reaction yields, and sat down with QA leads to study records of past batch inconsistencies. We heard about the cost of downtime, the frustrations of too-frequent equipment cleaning, and the steady overhead caused by byproduct accumulation.

    Breaking Down the Model and Specification Details

    Z-Orn-OH’s core specification ties directly to material integrity and operational consistency. Instead of focusing on being all things to everyone, we chose a targeted approach: a single, stable model that performs well under real-world manufacturing stress. Spec sheets and third-party certifications show our average purity lands above 99.5% for every batch, but direct customer feedback convinced us to manage even the last fraction of a percent using advanced purification and closed-system transfer.

    Our plant runs use direct monitoring of every critical parameter—temperature, pressure, solvent ratios—to make sure crystal phase and moisture content never drift. Technicians recharge drying towers regularly and sample for infra-red spectrometry more than industry averages—proactive oversight, not compliance checkbox routines. While lab-controlled batches can look pretty on paper, our experience says large-volume production is the true test. Z-Orn-OH has always been manufactured on continuous lines calibrated to hold parameters tight; technicians have direct visibility over line status, so tweaks happen in minutes, not hours.

    Customers tend to ask about trace metals, halide background, and specific organic residue levels. Here, we went the extra mile. GC-MS and ion chromatography reports for Z-Orn-OH consistently show total impurities below 0.05%, with most test suites picking up only background signal. QA leads push hard to keep these numbers steady, especially given how certain downstream processes—like catalyst synthesis, surface modification, and composites blending—react to stray ions or residuals. Unplanned outcomes often trace to some overlooked impurity or water pickup during transfer; our dedicated handling protocols cut those risks.

    Real-World Applications: Where Z-Orn-OH Proves Its Value

    Some products hover in the “nice to have” category. Z-Orn-OH punched its ticket by consistently solving hard problems. Take polymer manufacturing for high-tolerance film and fiber; our partners often struggle with unpredictable results from inconsistent raw stock. Z-Orn-OH’s tight purity range and stable reactivity help cut variation workload and minimize off-spec runs. This leads to easier troubleshooting—more time solving root problems, less time chasing dead-ends caused by mystery contaminants.

    In catalyst R&D, even subtle changes in feedstock output can set back entire weeks of work. Here, Z-Orn-OH’s stable composition lets researchers pin down true root causes instead of worrying about background variability. Surface sciences teams have had similar experiences. Coating and interface specialists who rely on predictable reaction profiles have reported fewer failures during scale-up, which means projects stay on schedule, and teams spend less time on backup plans.

    High-purity requirements really stick out in battery materials development, advanced ceramics, and optical-grade compounds. Most legacy products bring along side reactions or trace organic leftovers, leading to unpredictable outputs or reduced shelf lives. Our lab spend years tracking these failure points—Z-Orn-OH answers by holding impurity levels low and moisture risk near zero, allowing better repeatability in compounded or doped materials.

    Comparing Z-Orn-OH and the Rest: Where Experience Splits the Difference

    Over the decades, we’ve put plenty of other products through their paces—major household names, specialty blends, various imports. Our process engineers stacked Z-Orn-OH head-to-head against these, running back-to-back line trials with real-world process interruptions. We tracked throughput, downtime from cleaning, reactivity drift, and side reaction formation.

    Mid-run, even minor differences show up quickly. Many competing products come from multi-purpose plants or third-party resellers, where even tiny inconsistencies in supply lead to frustrating process hiccups. Older grades lag behind on moisture exclusion and purity maintenance during packaging. In our experience, that’s where a lot of failures and out-of-spec output really start. Z-Orn-OH’s dedicated production and quality oversight dramatically lowers those points of failure.

    Customers hammer home that “just good enough” quality rarely makes the cut for critical path projects. Z-Orn-OH stands apart due to this focus on reliable, tight-specification output—batch after batch, not just in marketing literature but on every plant floor we serve. Even the finer points, like rapid dissolution or surface behavior, matter. Where many alternatives clump or bring unpredictable flow, we closely monitor screening and sizing, so Z-Orn-OH pours and disperses without fuss. We keep particle mechanics in-house, where operators can tweak real equipment and test lots on actual pilot runs, not just theoretical lab setups.

    Listening to End Users and Product Development Teams: Why Feedback Defines Quality

    On weekly calls, technical teams walk us through their latest hiccups—sometimes between shift changes, sometimes mid-experiment. That’s where decades of hands-on experience count. Z-Orn-OH’s evolution came from these uncensored conversations. Too many products in this market are built far from the grind of day-to-day production; we believe success depends on working side-by-side with the people who know every shortcut and every failure mode.

    Last spring, for instance, a major customer in the coating sector let us shadow their techs as they worked a 24-hour cycle. We watched as they mixed under near-zero ambient humidity—Z-Orn-OH kept reactivity stable when competitors built up static and produced spot defects. In thin-film applications, where clarity and defect rates set budgets, details like this turn into real money. After a half-dozen successive process improvements, their yields climbed and downtime fell sharply; engineers traced the gains straight to tighter raw input quality.

    Academic groups exploring energy storage chemistries frequently ring us to ask about lot-to-lot jumpiness in competitive products. In these fields, a single anomalous batch can disrupt whole grant cycles. Working alongside these labs, we dug into past failures, mapping issue patterns to subtle raw material shifts on imported products. Z-Orn-OH held the line with each delivery, freeing researchers up to push projects forward.

    Addressing Common Customer Challenges: Getting Beyond Band-Aid Solutions

    Chasing root causes beats short-term bandages every time. Line managers tell us so often: “If the raw chemicals behave, the rest of our machines keep running.” Z-Orn-OH doesn’t just clear arbitrary inspection checklists; it tackles the storm of real production demands—mechanical agitation, temperature swings, long storage, and batch blending. By cutting down speculation about input integrity, Z-Orn-OH lets teams direct their skill toward real issue-solving, not endless troubleshooting.

    We tackled storage stability by dialing in moisture-resistant packaging lined and sealed at origin. Line-side deployment carried over that focus, with detailed guidance for in-house handling and dispensing. Years ago, legacy products often absorbed water during warehouse storage or transit; in humid zones, this led to reaction shifts or blocked lines. With Z-Orn-OH’s improved barrier systems, those calls dropped off—a sign installation techs noticed the change.

    One overlooked area is process adaptability. Some older grades fall short unless conditions are “just right”. With Z-Orn-OH’s controlled particle size distribution and low static affinity, it fits into different process flows, from inline mixers to automated dosing lines, as well as slower, hand-loaded applications. This saves our customers the cost and hassle of constant line reconfiguration, retraining, and specialized cleaning schedules.

    Honing Quality at Every Step: It’s About Process, Not Just Product

    No process gets better by magic. Our facilities run on the principle that watching every step—from raw input to sealed shipment—cuts down surprises. Z-Orn-OH’s production line includes more than just reactors and dryers. It’s about sharp-eyed operators constantly catching small anomalies before they snowball. We run scheduled maintenance cycles based on equipment age and fault data, not just calendar dates, so downtime rarely catches us off guard.

    After switching to more frequent in-process sampling, we cut rework and “hold for inspection” lots by a large margin. Part of our effectiveness comes from having floor staff recognized for calling attention to near-misses; those on the ground see the first signs of trouble, from an odd odor to a pump vibration out of line. We encourage reporting, confirm with real-time checks, and act quickly before a problem runs downstream and multiplies.

    Shipping Z-Orn-OH, we use pre-cooled, container-liner equipped transport for long-haul movements—especially in hot climates or during peak humidity. Customers in tropical zones told us in the past about condensate or caking at delivery with less robust packaging. We responded with tighter QA, better seals, updated lot-tracking, and a full chain-of-custody record that follows every shipment. Feedback from buyers shows that trusted delivery beats any discount offer.

    Professional Training and Onboarding: Ensuring Teams Use Z-Orn-OH to Its Full Potential

    Supplying a refined chemical means more than just shipping barrels or bags. Many plant teams come to us with specific questions or requests for application tips. We run in-person training for both new and experienced operators, focused not just on paperwork but how raw material characteristics affect specific process equipment, mixing speeds, storage, and runtime scheduling.

    Teams see examples from many sectors: battery assembly, high-reliability coatings, filtering special runs for optics, or scaling pilot line results to commercial output. They report back with new insights, which feed directly into our own process improvements. That closed loop—sharing knowledge between manufacturer and end user—keeps product quality and plant efficiency high. With Z-Orn-OH, technical support goes well beyond phone scripts; we send experienced staff on-site to help solve problems and learn from those who work with our products day in and day out.

    Commitment to Environmental and Worker Safety: Meeting Real-World Standards

    We manufacture Z-Orn-OH under strict environmental controls because long-term viability depends on doing things right for both planet and people. Ventilation, spill control, and recycling protocols are based on field experience, not just theory. On-site workers receive hazard training and regular hands-on drills, not just computer-based modules. The plant is wired for immediate reaction to leaks or exposure; first-responder kits and communication points stay updated and tested.

    Waste handling and run-off control evolved from past incidents—not hypothetical risk, but actual lessons learned. Solvent recovery lines redirect volatile emissions, and all effluent undergoes chemical and biological check before discharge. Customers increasingly ask for details on process sustainability, and we’re happy to walk through real maintenance logs and inspection protocols. Z-Orn-OH’s manufacturing doesn’t trade off speed for safety; our regular audits keep management alert and engaged.

    Our teams recognize that chemical supply doesn’t stop at the plant gate. For every batch, lot-traceability links back to both input origin and outbound handling records. Environmental concerns now drive product selection for many procurement leads. With detailed lifecycle analysis on Z-Orn-OH, customers see that what happens before the delivery matters as much as what happens after. The product gets recognition not just for its technical merits, but because partners know they’re buying from operations that invest in real worker and community safety.

    Product Improvement and Future Innovation: Z-Orn-OH as a Platform for Growth

    Every customer insight sparks ideas for new ways to tweak Z-Orn-OH. Regular collaboration with universities, testing companies, and downstream partners feeds targeted R&D. The product ‘lock-in’ that comes from constantly listening keeps Z-Orn-OH relevant as markets evolve—battery chemistries shift, new environmental rules roll in, and advanced manufacturing lines get more automated.

    We continue adjusting process recipes and monitoring outcomes, comparing every tweak against field feedback. The goal remains: make incremental, real improvements that pass the test of high-volume, high-stakes operation. Even as demand shifts or expands into new fields, we keep investing in both continuous line upgrades and operator training. Our customers deserve chemistry that keeps pace with their business—not just for individual experiments, but with every scale-up, every regulatory cycle, every shift in technical workforce.

    Z-Orn-OH isn’t simply a product off a catalog shelf—it’s born of practical manufacturing knowledge, hundreds of combined years on the plant floor, and a genuine partnership with customers. By tackling tough process challenges and embracing honest feedback, we keep pushing chemical performance forward. We welcome ongoing feedback, new challenges, and deeper collaboration from every sector that relies on well-made, well-supported materials.