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Trimethyl-Pyrazine

    • Product Name Trimethyl-Pyrazine
    • Alias TMP
    • Einecs 219-069-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    646899

    Cas Number 14667-55-1
    Chemical Formula C7H10N2
    Molecular Weight 122.17 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Nutty, roasted, cocoa-like
    Boiling Point 172-174°C
    Melting Point -14°C
    Density 1.03 g/cm3 (20°C)
    Solubility In Water Slightly soluble
    Refractive Index 1.498 (20°C)
    Flash Point 57°C (closed cup)
    Purity Typically ≥98%
    Storage Temperature Store in a cool, dry, and well-ventilated place
    Stability Stable under normal conditions
    Main Uses Flavoring agent, fragrance intermediate

    As an accredited Trimethyl-Pyrazine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Trimethyl-Pyrazine is packaged in a 250g amber glass bottle, with a tightly sealed cap and a clear hazard label.
    Shipping Trimethyl-Pyrazine is shipped in tightly sealed, clearly labeled containers to prevent contamination and leakage. It is transported as a non-hazardous chemical under normal temperature conditions. Packaging complies with regulatory standards to ensure safety during transit. Appropriate documentation accompanies the shipment, detailing handling instructions and emergency contact information.
    Storage Trimethyl-Pyrazine should be stored in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials like strong oxidizers. Keep the container tightly closed when not in use. Store in a suitable, labeled chemical storage cabinet, preferably at room temperature. Ensure proper containment to prevent leaks or spills, and follow all applicable safety regulations and guidelines.
    Application of Trimethyl-Pyrazine

    Applications of Trimethyl-Pyrazine in Industrial Manufacturing

    Trimethyl-pyrazine is widely recognized and utilized across several high-value industrial sectors due to its unique aromatic profile, thermal stability, and regulatory acceptance. Our manufacturing expertise ensures strict control from synthesis to quality management, supporting customer production in demanding environments. Below we detail major application scenarios where our trimethyl-pyrazine plays an essential role in downstream processes.

    1. Food Flavoring Additives – Savory and Snack Sector

    Major processed food manufacturers incorporate trimethyl-pyrazine to impart roasted, nutty, and baked notes in savory snacks, instant noodle seasonings, meat analog products, and bakery applications. The substance integrates during the blending phase for compound flavor systems or is dosed directly into seasonings and premixes. Our customers adjust concentration based on matrix, fat content, and target flavor profile, consistently passing global food safety audit trails.

    Industry compliance standards

    • GB 2760 (China National Food Safety Standard for Use of Food Additives)
    • European Regulation (EC) No 1334/2008 on flavorings and certain food ingredients
    • U.S. FDA 21 CFR 172.515 (Permitted Flavoring Substances)
    • JECFA evaluation and FEMA GRAS listing (#3238)

    Typical usage ratio

    • 5–50 mg/kg in compound flavors; typical adjustment based on total seasoning mass, matrix volatility, and regulatory maximum levels

    Downstream process integration

    • Dosed into batch blending tanks during flavor compounding or pre-mix formulation; suitable for both liquid and powder flavor systems; may be added before spray drying or directly into dry blending lines

    Final product types

    • Potato chips and extruded snacks
    • Processed meat seasonings and fillings
    • Soy-based meat analogs
    • Baked bread and cracker products

    2. Tobacco Processing and Casing Formulation

    The tobacco industry employs trimethyl-pyrazine as a flavor enhancer to accentuate the desirable roasted and nutty notes in cigarette, cigar, and shisha blends. Proper integration occurs at the aromatic casing and flavoring step, requiring strict adherence to industry purity and traceability requirements. Our production supports large-scale casing producers and directly supplies tobacco blend manufacturers demanding consistent analytical specifications.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management Systems for tobacco flavor manufacturers)
    • European Union Directive 2014/40/EU on Tobacco Products
    • China GB 2760-2014 for tobacco additives
    • Internal BAT/JTI/Philip Morris supplier quality guidelines

    Typical usage ratio

    • 3–40 mg/kg tobacco for final flavored blends; adjustments according to tobacco grade, cut size, and desired aromatic intensity; in casing formulations, can reach up to 0.01% (w/w) in flavoring agents

    Downstream process integration

    • Incorporated during application of casing and top flavorings; typically prepared as part of a liquid flavor concentrate sprayed onto processed tobacco laminae or processed within reconstitution sheet lines

    Final product types

    • Cigarette tobaccos
    • Pipe and hookah tobacco blends
    • Premium cigars

    3. Coffee and Beverage Flavors

    Leading beverage and instant coffee manufacturers utilize trimethyl-pyrazine for enhancing roasted and chocolate-like notes. It is particularly valued in coffee aroma recombination, cocoa-flavored beverages, and high-temperature UHT creamers. It enters the production line at the flavor house or is directly dosed into the beverage blend pre-heat treatment, and careful process validation is required to ensure consistent volatility capture and sensory outcome.

    Industry compliance standards

    • Codex Alimentarius STAN 192-1995 (General Standard for Food Additives in beverages)
    • EU Regulation (EC) No 1334/2008 on flavorings
    • FSMA (US FDA Food Safety Modernization Act)
    • COFFEE Quality Standards (SCA, ICO guidelines)

    Typical usage ratio

    • 1–20 mg/kg in beverage flavor bases; tailored based on extraction loss during spray drying, reconstitution, or high-temperature homogenization

    Downstream process integration

    • Added to liquid aroma top notes in instant coffee and cocoa beverage flavorings; pre-blended in liquid or encapsulated forms for beverage premixes; introduced to the inline blending stage prior to final UHT or aseptic filling

    Final product types

    • Instant coffee powders and granules
    • Ready-to-drink coffee beverages
    • Chocolate and malt-flavored UHT drinks
    • Coffee creamers and whiteners

    4. Pet Food Palatant Formulation

    Trimethyl-pyrazine serves as an effective palatability enhancer in dry and semi-moist pet food, recognized for its ability to simulate roasted meat aromas and encourage feed intake in cats and dogs. Manufacturers dose the compound during the liquid palatant spray or resin top-coating phase after extrusion and drying. Regulatory controls require allergen tracing and batch documentation throughout the process.

    Industry compliance standards

    • AAFCO Official Publication (US FDA Standard for Pet Food Ingredients)
    • FEDIAF Guide to Good Practice for the Manufacture of Safe Pet Foods (Europe)
    • Regulation (EC) No 767/2009 on the marketing and use of feed
    • ISO 22000 Food Safety Management for pet food producers

    Typical usage ratio

    • 8–40 mg/kg in palatant systems for extrusion-coated kibbles; dosage fine-tuned for palatability trials and animal taste panel feedback

    Downstream process integration

    • Dispersed or solubilized in liquid palatant, sprayed post-extrusion after drying; compatible with both water and oil-based coating systems, applied to kibble surface on drum coater lines

    Final product types

    • Extruded dry dog and cat food
    • Semi-moist pet treats
    • Palatability enhancers (sold to other feed producers)

    5. Pharmaceutical Intermediate for API Synthesis

    Certain pharmaceutical synthesis chains include trimethyl-pyrazine as a process intermediate or reactant for specific active pharmaceutical ingredients, particularly where pyrazine core structures are pharmacologically relevant. Materials must meet high-purity and trace-level impurity standards. Production scale customers integrate the raw material within GMP-validated synthetic steps, frequently followed by multi-stage purification and regulatory documentation.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF and European Pharmacopoeia monographs (when applicable for final API)
    • China Pharmacopoeia (if produced or used in China)
    • Customer-specific impurity and trace metal control protocols

    Typical usage ratio

    • Used as a process intermediate at stoichiometrically defined levels, typically 1–5 mol%, subject to reaction pathway; not present in final API, decomposed or converted during synthesis

    Downstream process integration

    • Charged into chemical synthesis reactors as a nucleophile or aromatic precursor, often at the pre-crystallization step or in early-stage amide coupling reactions; integrated into multi-step batch or continuous-flow API process

    Final product types

    • Heterocyclic pharmaceutical actives (various therapeutic classes)
    • Key intermediate substances for custom synthesis (CDMO projects)
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    Certification & Compliance
    More Introduction

    Trimethyl-Pyrazine: Consistent Quality Starts at the Source

    Experience at the Manufacturing Bench

    Trimethyl-Pyrazine’s unique character doesn’t come from marketing stories or flashy packaging. Its value comes from exacting attention during production and careful selection of every raw material step. From the view in our plant, there’s no shortcut to producing a batch with pure aroma and consistent performance. Over the years, chemists and process engineers have tweaked reaction conditions, adjusted purification steps, and learned how minor changes to time, temperature, and even local humidity can alter the profile. Those changes matter every time that powdered Trimethyl-Pyrazine leaves our facility.

    Many folks outside the plant may not realize just how sensitive pyrazine chemistry can be. Experienced noses pick up off-notes or muted character in blends that rely on commercial material purchased through brokers and channel dealers. Our team has noticed that sourcing from large-volume resellers often introduces variability—sometimes due to old stock, sometimes from uncontrolled storage. By manufacturing entirely in-house, we track every variable and batch, from reactor throughput to intermediate storage, which means a reliable profile in every lot.

    The Craft of Trimethyl-Pyrazine Synthesis

    Compared to simple pyrazine, the trimethylated version offers a much stronger, toasted, nutty scent and a distinctive cocoa or popcorn aroma. Subtle balance sets it apart. By controlling methyl group distribution and achieving low residual solvent, we avoid the green or musty notes that sometimes slip into lower-spec batches. Tight process control enables us to reach very high purity—this leads to lower required dosages and keeps recipes cleaner on ingredient lists.

    It’s not just purity as a technical specification. Taste panels in our pilot lab repeatedly demonstrate that precise methyl substitution patterns matter. The aroma rises and persists, amplifying flavors in both savory and sweet formulations. In food, beverage, and even tobacco flavoring, small differences in manufacturing translate into large shifts in the consumer’s sensory experience.

    Specifications That Actually Matter

    In our production plant, technical data isn’t marketing filler—it guides hands-on decisions. The preferred format comes as a free-flowing, off-white crystalline powder with a mild but penetrating aroma. We confirm GC purity above 99%, and routinely check for common contaminants from starting materials and side reactions.

    Color, melting point, and moisture all affect handling. Storage in humidity-controlled conditions ensures clumping never ruins a batch. Our packing lines fill vacuum-sealed, light-resistant containers to fend off the gradual aroma loss that plagues poorly stored material.

    Key Differences from Other Flavors and Pyrazines

    Trimethyl-Pyrazine stands apart from ethylpyrazines or dimethylpyrazines. It delivers a rounder, less sharp note—some say almost chocolatey—while other pyrazines skew toward green, earthy, or beany profiles. Our formulators frequently use it to round off rough edges in nut flavors or to add depth to caramel and brown flavors. In comparison, lower methylation levels can’t achieve the same fullness without introducing off-flavors.

    We have evaluated side-by-side blends in model confectionery, cereal, and dairy flavorings. The difference jumps out in milk-based applications, where the warmth and richness of Trimethyl-Pyrazine smooth over hard dairy notes and enhance toasted qualities without overpowering. Customers often report that blends from third-party houses fail basic taste panel tests, with muted top notes or harsh undercurrents—usually traced back to inconsistent or outdated supply.

    Applications That Drive Product Development

    Our R&D team works with hundreds of flavorists and food technologists each year. Most start with requests for consistency in aroma, purity, and long-term shelf life. Trimethyl-Pyrazine fits into chocolate, nut, popcorn, roasted coffee, and baked good applications. It also features in seasoning blends for snacks and in certain ready-to-eat savory products where a warm, brown aroma is essential.

    Across markets, manufacturers demand uniform aroma and no lingering bitterness or metallic aftertaste. These requirements call for full control over residue and impurity levels, beyond a basic purity figure. We test for common byproducts and keep levels well below international flavor ingredient limits. Some buyers use it in functional foods, where label claims and aroma intensity demand a high standard.

    Handling, Storage, Shelf Life

    Technical staff in end-use factories report that fine free-flowing crystalline material integrates rapidly into batters, syrups, and oils, speeding up processing time and helping scale-up. Dusting and loss during handling can lead to wasted raw material. We tackle this by adjusting particle size and moisture to minimize powder fly-off and ensure even addition.

    Most flavor compounds risk loss through oxidation, light, or humidity. We’ve invested in specialized packaging to get the most aroma stability over the product’s working life. Storing in cool, dry, and dark conditions, ideally in unopened original containers, preserves quality longest.

    Production Volumes and Consistency

    Scaling from pilot to commercial batches always reveals weak points. We’ve fine-tuned our batch size for tight quality control. Whether shipping twenty kilograms for a multinational customer or five hundred grams for an independent flavor house, each run meets the same strict parameters. Our people check analytical data batch-by-batch, not just by sampling one in every hundred.

    Through downturns and booms in global supply, we maintain buffer inventories of raw materials. Supply chain interruptions don’t change our specifications or hold up orders. We don’t cut corners or blend older lots to meet contract targets, since traceability protects both our name and the reliability of processed food partners.

    Why Purity and Freshness Affect Outcomes

    Flavor innovation gives companies an edge, and clean flavor delivery starts at the core aroma ingredient. In chocolate or nut flavors, for instance, minor impurities in trimethyl-pyrazine bring out bitterness and mask intended brown notes.

    Older or poorly stored stock picks up off-odors over time. That happens when resellers move surplus through damp warehouses or blend unsold lots. By producing to order in small lots and controlling every handoff, we avoid these pitfalls.

    National regulators now require flavor producers to document full traceability—missing certificates or poorly documented sourcing can slow a new product launch. We archive every batch production record and test result, ready to support partners in meeting regulations.

    Choices in the Lab and on the Line

    Conversations with professional flavorists usually turn to performance in actual recipes. Our laboratory panels assess blends in finished food systems, not just in neat solutions. This detects interaction with fats, sugars, and other aroma chemicals. Findings shape changes in production—say, adjusting distillation rates or using optimized drying parameters to avoid carrier aromas from the equipment itself.

    In the factory, material flow and dosing accuracy reduce both costs and labor time. Our powder form suits continuous blending lines. Finer grades can clog feeders, while too-coarse material disperses unevenly. Through trial and error, we’ve settled on a medium particle size that balances wettability and dust minimization.

    Working Direct with Manufacturers

    Direct buyers benefit from partnering closely with our technical staff. By skipping distributor markups and communicating lab-to-plant, we eliminate uncertainty about product age, out-of-spec lots, and unknown blends. Field experience proves that trimethyl-pyrazine in its freshest form delivers a top note that can’t be matched by aged or blended material.

    We acknowledge that flavor launches don’t always run on schedule. Production delays can leave warehouses full of unsold stock for months. By operating on a made-to-order rather than stockpiling model, we avoid off-odors linked to aged pyrazines, guaranteeing a fresher result for your next batch.

    Flexibility for R&D and Commercial Scale

    Major clients often send us feedback from pilot trials: dose-response curves, descriptive flavor notes, and consumer panel results. We use this data to provide custom lot sizes, special handling, or altered packing for R&D as well as for standard manufacturing. For smaller customers, smaller packages prevent needless waste and keep costs in check. In both cases, the purpose is the same—tailor to each application, ensure reliable quality, and minimize turnaround.

    Because we control the entire production chain, unusual requests don’t slow us down. Need a specific particle size to trial a new blend? Want a set of analytical results to match with internal house methods? We can meet these needs without delay.

    Solutions to Common Industry Challenges

    From our position on the factory floor, the stories we hear line up: Variability in flavor supply slows launches and raises rejection rates. Lab staff and buyers struggle to reconcile certificates of analysis with actual aroma quality. Some need help reconstructing misplaced batch records after regulatory audits. Others discover their broker-sourced pyrazine has oxidized through poor storage and can’t achieve the desired aroma.

    By manufacturing in-house and maintaining lot-by-lot documentation, we tackle these pain points. Our robust tracking means batches are always traceable. Analytical records stay on file for years. We retain reserve samples in controlled conditions, so issues in customer applications can be traced back. If a food manufacturer faces a sensory deviation, our staff can run side-by-side analysis to pinpoint whether the base flavor or an added ingredient caused the change.

    A proactive approach—regular QC, solid documentation, consistent communication—yields long-term stability in finished products. Our hands-on knowledge means we’ve lived through recalls, product failures, and unexpected stability studies, each time investing in improvements that pay forward for our partners.

    Supporting Clean Labels and Regulatory Compliance

    The move toward clean label and transparent supply chains changes how manufacturers like us operate. We understand that regulatory and labeling pressures trickle down to flavor suppliers. Each batch of trimethyl-pyrazine meets strict food-grade standards, but that’s just a baseline. Our facility protects against cross-contamination, and ingredients never share process streams with allergens or animal-derived materials. This helps our partners answer retailer audits and regulatory reviews with documented, chain-of-custody records.

    Short shelf life or unexpected sensory changes can wreck a clean-label project. That’s why we retain production samples, offer technical support during new product development, and update partners on process changes well in advance. In customer feedback, technical teams highlight the clarity and speed of our support as much as the technical merits of our material.

    Real Experience Yields Real Value

    There’s no substitute for years of hands-on production and problem-solving in specialty pyrazines. Our flavorists, production chemists, and packing staff don’t just interpret paper spec sheets. They taste sample blends. They check for losses or shifts at every point, from raw goods to finished sealed packs.

    Distributors can't replicate this direct oversight. Nor do they offer the reassurance that comes from working with a team that knows how even slight inconsistencies can unravel a new flavor launch. From the moment a batch enters our reactors to final dispatch and customer blending, each staff member knows their work shapes the outcome in foods enjoyed around the globe.

    Why Direct Sourcing Delivers Superior Results

    Trimethyl-Pyrazine forms the backbone of iconic flavor systems in chocolate, roasted nuts, savory snacks, and premium beverages. Our role as a manufacturer means every kilogram represents more than a line on a certificate—it embodies invested experience and pride in a trusted food supply.

    The challenges we face—raw material swings, scale-up issues, evolving standards—are matched by opportunities to innovate and sustain strong partnerships. By listening to those who actually touch the process, from flavorist to machine operator, we keep the bar for quality and service high.

    We invite food, beverage, and flavor leaders to visit, inspect, and experience the ways direct-from-source trimethyl-pyrazine will raise the bar in finished products. Honest feedback and continued collaboration lead to long-term improvements for everyone in the value chain. Our plant doors are always open for those who want to see what it means to build quality from the ground up.