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Trans-Ferulic Acid

    • Product Name Trans-Ferulic Acid
    • Alias TRANS-FERULIC
    • Einecs 230-022-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    826702

    Chemical Name Trans-Ferulic Acid
    Molecular Formula C10H10O4
    Molecular Weight 194.18 g/mol
    Appearance White to light yellow crystalline powder
    Solubility Slightly soluble in water, soluble in ethanol and DMSO
    Melting Point 174-176°C
    Cas Number 537-98-4
    Ph Value Acidic
    Storage Temperature 2-8°C
    Purity ≥98%

    As an accredited Trans-Ferulic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Trans-Ferulic Acid, 25g: Supplied in a sealed amber glass bottle with screw cap, labeled with product details and safety information.
    Shipping Trans-Ferulic Acid is shipped in tightly sealed containers to protect it from moisture, light, and air. It is packaged according to standard chemical transport regulations, typically in secure, labeled bottles or drums, and placed within protective packing materials to prevent damage during transit. All shipping complies with safety and handling guidelines.
    Storage Trans-Ferulic Acid should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, ideally at 2–8°C (refrigerated conditions). Avoid exposure to extreme temperatures and sources of ignition. Properly labeled storage and adherence to chemical safety guidelines will help maintain its stability and prevent deterioration.
    Application of Trans-Ferulic Acid

    Applications of Trans-Ferulic Acid in Industrial Manufacturing

    As a direct manufacturer, we focus on supplying high-purity trans-ferulic acid to global industrial customers who require its functional properties in regulated, high-value sectors. Our production and technical team supports multiple precise downstream applications in line with strict international standards.

    1. Cosmetic Antioxidant Additives (Skin Care Formulations)

    Industrial customers in cosmetic manufacturing incorporate trans-ferulic acid as an active antioxidant and photoprotective stabilizer, particularly within advanced skin care products formulated to mitigate UV-induced oxidative damage. It is widely favored for stabilization of vitamins C and E in combination serums and creams. Bulk users integrate it during the post-emulsion cooling phase to prevent degradation and maximize preservative-free shelf life. Product acceptance depends on verification methods including HPLC content analysis and in-process QC under GMP and ISO22716 compliance.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 on Cosmetic Products
    • US FDA 21 CFR 700.3 Cosmetics Labeling
    • ISO 22716: Cosmetics — Good Manufacturing Practices (GMP)
    • Chinese Safety and Technical Standards for Cosmetics (2021)

    Typical usage ratio

    • 0.05%–0.5% by weight in finished creams and serums; exact concentration adjusted depending on the photostability requirements of vitamin matrices and target SPF stabilization.

    Downstream process integration

    • Added during the cooling phase of emulsion synthesis to avoid thermal degradation; soluble in ethanol or select glycols; monitored by QC for homogenization; batch record includes content verification using validated HPLC methods.

    Final product types

    • Antioxidant facial serums
    • Day and night creams with enhanced UV protection
    • Photo-stabilized sunscreen lotions
    • Vitamin-based anti-aging ampoules

    2. Pharmaceutical Intermediate for Injectable Formulations

    Pharmaceutical manufacturers use trans-ferulic acid as a bioactive intermediate for the preparation of injectable anti-inflammatory and circulation-promoting formulations, particularly in China and Japan. It serves as a key synthetic precursor for sodium ferulate and other ester derivatives, which are included in hospital-grade ampoules and lyophilized powders. Manufacturers source it in GMP-compliant, low-endotoxin grades for strict traceability. During downstream processing, operators dissolve and filter it under aseptic conditions before chemical modification and sterilization procedures.

    Industry compliance standards

    • Chinese Pharmacopoeia (CP 2020)
    • Good Manufacturing Practice (China GMP 2010, EU GMP)
    • USP/NF reference for intermediate synthesis
    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients

    Typical usage ratio

    • Intermediate: 1–10 g/L in pharmaceutical synthesis reactors; adjusted based on required batch output and subsequent derivatization yield for injectable preparations.

    Downstream process integration

    • Dissolved in purified water or ethanol in reaction vessels; chemical derivatization (e.g., sodium salt formation); filtered and sterilized for aseptic fill; in-process controls for purity, microbial content, and residual solvents.

    Final product types

    • Sodium ferulate injection ampoules
    • Lyophilized anti-inflammatory vials
    • API precursors for hospital supply
    • Circulation-improvement injectables

    3. Functional Food Ingredient in Fortified Products

    Functional food processors integrate trans-ferulic acid during the formulation of fortified snack bars and beverages aimed at the health and nutrition market, particularly in Asia. The compound contributes natural antioxidant properties and supports claims related to oxidative stress reduction. Regulatory authorities limit the allowable concentration in finished food per local and international guidelines, requiring processors to validate analytical content at the final blending stage. Blenders introduce it pre- or post-extrusion depending on the desired bioavailability and processing temperature of the matrix.

    Industry compliance standards

    • GB 2760-2022 (China: Standards for Use of Food Additives)
    • Food Chemicals Codex (FCC)
    • Japan Food Sanitation Act (Food Additive Standards List)
    • ISO 22000:2018 Food Safety Management Systems

    Typical usage ratio

    • 20–100 mg/kg in functional foods and ready-to-drink beverages; dosage limited by national food safety rules and adjusted according to the declared antioxidant content and organoleptic profile.

    Downstream process integration

    • Introduced into mixing hoppers prior to extrusion (for bars); added during solution blending for functional beverages; QC verification by spectrophotometric or LC-MS/MS analysis prior to packaging.

    Final product types

    • Fortified grain bars
    • Dietary meal-replacement drinks
    • Functional health beverages
    • Antioxidant-boosted confectionery

    4. Stabilizer in Industrial Polymer Processing

    Plastic and packaging manufacturers select trans-ferulic acid as a thermal and UV stabilizer, predominantly within high-performance polymer compounds where non-toxic antioxidant activity is critical. Compounders blend it into thermoplastic resins such as polyethylene or polypropylene during melt compounding to improve process stability and extend end-use product lifespan. The selection and certification of raw material must match downstream compliance targets for food-contact and consumer packaging applications.

    Industry compliance standards

    • EU Regulation (EU) No 10/2011 on plastic materials and articles intended to come into contact with food
    • US FDA 21 CFR 177.1520 (Olefins for Food Contact Applications)
    • ISO 9001:2015 (Quality Management in Polymer Production)
    • Chinese GB 4806.7-2016: National Food Safety Standard for Plastic Food Contact Materials

    Typical usage ratio

    • 0.02%–0.2% by weight in final polymer composition; ratio depends on target light resistance and allowable migration limits for food packaging.

    Downstream process integration

    • Directly incorporated into masterbatch or compound during high-shear extrusion; blended at melt stage under controlled temperature to maintain antioxidant activity; batch samples analyzed by GC or HPLC for additive content and distribution.

    Final product types

    • Food-grade plastic films
    • High-barrier packaging materials
    • UV-resistant containers and lids
    • Microwaveable trays

    5. Fine Chemical Synthesis Building Block

    Producers in the fine chemical sector utilize trans-ferulic acid as a key building block for the synthesis of ferulate esters, aromatic aldehydes, and phenylpropanoid derivatives. These downstream compounds serve as intermediates for flavors, fragrances, and pharmaceuticals. The material demands precise analytical characterization for reaction monitoring, and strict quality controls in line with global chemical manufacturing standards. Industrial reactors or semi-batch synthesis lines introduce it at the start, with careful monitoring of reaction completeness and by-product formation.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 (Chemical Registration in EU)
    • ISO 9001:2015 certified operation
    • Chinese National Standard GB/T 19001-2016/ISO 9001:2015
    • IATA Dangerous Goods Regulations (for downstream export of derivative chemicals)

    Typical usage ratio

    • Varies from 5%–25% molar input depending on target derivative; optimized for maximum conversion efficiency and minimized excess reactant under closed material balance principles.

    Downstream process integration

    • Charged at reaction start in glass-lined or stainless-steel reactors; combined with appropriate esterification or oxidation agents; controlled temperature and pH adjustments; in-process QC for conversion yield and purity by GC-MS or HPLC.

    Final product types

    • Ethyl ferulate and methyl ferulate (ester derivatives)
    • Vanillin precursors
    • Phenylpropanoid intermediates for flavor/fragrance manufacture
    • Pharma-grade synthetic aroma compounds
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    Certification & Compliance
    More Introduction

    Trans-Ferulic Acid: A Manufacturer’s View on Quality, Value, and Application

    Introduction

    Trans-Ferulic acid carries a recognizable profile among phenolic compounds, drawing attention across personal care, pharmaceuticals, and food technology sectors. Our experience manufacturing trans-Ferulic acid starts in the sourcing of raw plant material, always aiming to minimize variation and avoid unknowns in the supply chain. Plenty of vendors vie for business in this market, especially traders working off generic inventory, but the value of a solid origin cannot be overstated. From precise extraction to purification, strict process control marks the difference between high-quality trans-Ferulic acid and a lot of commodity-grade products circulating today.

    Model and Specifications: From Precision to Practice

    We focus on trans-Ferulic acid with a purity of at least 98%. Fine powders, almost white to faintly tan, come through micronization and high-efficiency filtration. The melting point usually sits around 174–178°C, and those handling the material know moisture content signals a lot about the integrity of the batch. Low water content, generally under 1%, supports shelf life, reduces agglomeration, and helps with blending in dry formulations. Some manufacturers, traders in particular, cut corners to save time; a few percentage points in moisture or process byproducts are all it takes to see crystallization shift or to pick up a faint odor from degradation.

    Particle size affects not just formulation flow but the rate and consistency of dissolution, especially in beverage, supplement, or topical use. Experience has shown that customers get frustrated if inconsistent clumping or odd colors start showing up in production runs. It’s easy to blame shipping or storage. Long before that, filtration steps and drying curves make or break the outcome.

    Trans-Ferulic acid’s solubility in water stays moderate at best, making ethanol or DMSO preferred for concentrated solutions. This nuance becomes vital in personal care, where formulating a serum or a lotion demands dispersibility without grittiness. Many assume all phenolic acids behave the same, but each structural variant brings its own quirks. The trans isomer delivers better antioxidant function in many systems compared to cis, thanks to a more linear molecular shape and better resonance stabilization in radical scavenging.

    Differences from Other Ferulates and Phenolic Acids

    Those new to trans-Ferulic acid sometimes confuse it with other ferulates, especially methyl ferulate or ethyl ferulate. Small shifts in molecular structure create noticeable differences in antioxidant potential, absorption rates, and even odor. Trans-Ferulic acid holds up better in high-temperature processes. Its radical scavenging action has proven robust under light and oxygen, where its methyl and ethyl counterparts degrade faster. In food applications, it provides more measurable protection against lipid peroxidation and color changes in fatty foods.

    Working from raw cinnamon, rice bran, maize, or wheat, extraction purity matters as much as the plant of origin. Hydroxycinnamic acids appear across the plant kingdom, but only select sources give clean, industrial-scale yields after processing. Too many batches on the open market turn up with unexpected contaminant profiles: polysaccharides, residual solvents, pesticide traces. Manufacturing at scale means running these analyses for every lot. One-off samples don’t reflect larger runs, and only repeated, rigorous testing provides assurance batch after batch.

    Why Usage Matters: Real-World Performance

    Personal care chemists prize trans-Ferulic acid for its synergy with vitamins C and E. Decades of research support claims that it slows the oxidative breakdown of ascorbic acid in serums, allowing longer-lasting potency. Real users expect that a formulation containing vitamin C and E plus trans-Ferulic acid outperforms a blend without it—this performance now drives not just innovation but regulatory scrutiny. Testing for free radicals, photostability, and shelf life holds meaning in global markets and shapes the advance of future formulations.

    Pharmaceutical uses rely on the stability and reactivity of the compound. Trans-Ferulic acid provides anti-inflammatory and antimicrobial activity, both in vitro and in vivo, according to published studies. Only a consistent, pure product avoids introducing variables into clinical results, which often cannot tolerate the batch-to-batch inconsistencies found in lower-grade supplies. In our manufacturing, HPLC testing double-checks identity and purity, and every deviation triggers rediscovery before release.

    Food technologists value trans-Ferulic acid for its ability to stabilize oils and enhance shelf life without synthetic preservatives. Once added to vegetable fats or spreads, it offers antioxidant capacity on par with BHT, but without the baggage of a synthetic additive. Its mild flavor and faint color mean formulators rarely need to compensate with masking agents—yet another reminder that not all batches behave the same. We hear from bar producers and margarine brands that visible yellowing or odd aftertastes often pinpoint low-grade or wrongly fractionated material from less attentive sources.

    Navigating the Manufacturing Edge: Experience Informs Process

    Transitioning from a lab-scale synthesis to industrial manufacturing means facing issues unseen at the bench. Extraction from agricultural feedstock introduces variables: growing conditions, storage time, varieties, and even the accuracy of sorting affect yields. Grainy, off-smelling extracts usually trace back to shortcuts in drying or solvent recovery. We learned long ago that repeated small-charged extractions deliver cleaner profiles and that pressure-vacuum-assisted drying reduces oxidation during concentration.

    On the chromatography front, specialized resins and tailored solvent gradients can drive up costs. Fine-tuning these parameters slows down the process, but the reward shows up in trace results and long-term product performance. Trace lignin or coumarin remaining in the product can bring subtle off-notes or regulatory headaches that ripple through the supply chain.

    Reaction vessels, filtration media, and temperature controls—all must line up to avoid introducing contamination or inconsistent profiles. We choose materials for contact surfaces carefully, knowing certain metals leach or react with phenolic compounds. It’s not uncommon to find a white paper promising “green” or “eco-extraction” from a startup, only to discover persistent impurities or instability in the final product. Our years of running lots through scale have highlighted the limits and advantages of new techniques. Clean runs of high-purity trans-Ferulic acid arise from deep process experience, not from promotional claims.

    Application Nuances: Beyond Simple Antioxidant Claims

    Every market demands something different. In cosmetics, trans-Ferulic acid tolerates exposure to a wider range of surfactants than most phenolic acids, offering heavier performance for UV-related claims. Lab batches routinely demonstrate lower peroxide values in model emulsions, confirming what R&D chemists expect from synergistic combinations. Incorporation into creams or gels works best with gentle heating and thorough mixing; uneven temperature gradients can trigger precipitation, especially at high concentrations.

    In dentistry, its mild antimicrobial role gives mouthwashes gentler profiles than stern, synthetic phenolics. User feedback and repeat testing tend to highlight smooth mouthfeel and reduced bitterness, both byproducts of well-controlled extraction and fractionation early in the process.

    Supplement developers keep a close watch on consistency, as tablets and softgels expose crystalline structure differences that low-volume producers seldom see. Binding and compression favor fine, stable powders. Unexpected hard spots or clumping hint at missed points in drying or unfiltered residues. We reformulate techniques with every customer inquiry, knowing the downstream process in each product line uncovers new layers of challenge.

    Market Considerations: Price, Reliability, and Trust

    Volume buyers negotiate on price, but rarely at the expense of reliability. A clinical trial or a mass-market launch means supply interruptions, trace failures, and regulatory lapses can do more damage than minor price differences in an ingredient. In our view, investing in analytical equipment and skilled technical teams brings more returns than stretching capacity to chase a rapidly fluctuating market.

    From our position, transparency counts more than ever. Each certificate of analysis must reflect true batch values, not generic numbers copied from a spec sheet. Buyers now demand origin, sustainability evidence, and contaminant screening down to trace levels. Sourcing from mapped fields, technical process logs, and thorough traceability efforts have elevated the expectations of buyers in Asia, Europe, and North America.

    Product recalls, missed launches, or inconsistent sensory properties all trace back to product quality. At our facility, internal audits, supplier vetting, and constant review of analytics make up the daily rhythm that stands behind every batch shipped. When market news covers false labeling, misidentified origins, or inflated purity numbers, all it does is underscore the need for a transparent, rigorous manufacturing cycle as the best shield against supply-chain risk and lost reputation.

    Some customers arrive after struggles with intermediaries; their stories ring familiar. Unexpected solubility issues, odor complaints, or unusual results in stability trials usually find roots in subpar purification or lax standards in early stage manufacturing. Addressing their needs often requires running extra filtration steps or even reprocessing compromised materials under stricter conditions. Building long-term partnerships with customers and end-users depends on not just solving the immediate technical gap, but also providing documentation and explanations clear enough for non-specialists to understand their choices.

    The Regulatory and Sustainability Edge

    Markets move beyond price and performance. Certification—GMP, ISO, Kosher, Halal, and more—now enters every discussion, and legitimate claims must be backed up by recognized processes, not just statements. Audits arrive unannounced; supporting documentation and compliance records can’t be assembled on short notice. We see regulatory shifts leading to restricted lists and tighter scrutiny each year. Food and cosmetics authorities now require more extensive provenance and safety data for phenolic acids, pointing to trace contaminants and process residues as causes of concern.

    Compliance isn’t an afterthought—it runs through the procurement of seeds and plants, the design of facilities, the training of operators, and the final packaging line. Skipping a documented cleaning step or running a shortcut in waste disposal risks contaminant buildup, fines, or shutdowns. Over the years, evolving regulatory clarity has brought forward more robust process checks and a shift away from legacy methods that could leave behind unwanted residues or create hard-to-trace batch inconsistencies.

    Trans-Ferulic acid extraction offers an opportunity for sustainability advances. We collaborate with local growers to create closed-loop sourcing, recycling spent biomass into animal feed or biogas where possible. Leaner process water usage and energetically efficient concentration steps contribute both to cost control and to smaller environmental footprints. Every customer inquiry now seems to check for sustainability practices, and end-consumers increasingly ask about traceability and responsibility filters. Ignoring these signals limits access to higher-value markets and alliances with major brands actively managing ESG scrutiny.

    Delivering Long-Term Value: Reflections and Forward Outlook

    We’ve watched the surge in demand for trans-Ferulic acid across sectors. Behind the rush lies a story of changing consumer priorities, regulatory expectations, and technical leaps. From initial sourcing to product delivery, only hands-on manufacturing knowledge ensures purity, repeatable performance, and safety. Each lot isn’t just a reflection of process expertise, but also an answer to buyer demand for more than just another antioxidant from a label.

    The work doesn’t finish at extraction or packaging. Customer service, technical troubleshooting, and constant process review play just as big a part. Whether a beauty brand needs paperwork for regional regulators or a supplement packager requires accelerated stability samples, those solutions arise from deep experience navigating both plant chemistry and global compliance. Substitution, fraud, and sudden spikes in demand continue to test the resolve and flexibility of every serious manufacturer.

    Feedback and technical partnerships drive continuous improvement. Regular reviews of process metrics, new fractionation methods, solvent management, and product handling form part of a closed-loop improvement culture that sustains both customer relationships and internal pride. Our commitment to data transparency, employee training, and customer education brings peace of mind far beyond any jump in batch capacity or unsustainable price discount.

    Ultimately, true progress means leaving behind just as many unquantified risks as possible—whether through better analytics, cleaner process innovations, or closer partnerships with growers and end-users. Trans-Ferulic acid production, at its best, gives more than one-time sales; it supports each buyer’s promise to their own customers and advances the whole field toward safer, higher quality, and more responsible ingredients.