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Trans-4-Methylcyclohexyl Amine

    • Product Name Trans-4-Methylcyclohexyl Amine
    • Alias 4-Methyl-1-aminocyclohexane
    • Einecs 249-180-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    922473

    Cas Number 4441-47-0
    Molecular Formula C7H15N
    Molecular Weight 113.20 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 169-170 °C
    Melting Point -1 °C
    Density 0.86 g/cm3 (at 25 °C)
    Refractive Index 1.457 (20 °C)
    Flash Point 54 °C (closed cup)
    Solubility In Water Slightly soluble
    Synonyms trans-4-Methylcyclohexylamine, trans-p-Methylcyclohexylamine

    As an accredited Trans-4-Methylcyclohexyl Amine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g amber glass bottle labeled "Trans-4-Methylcyclohexyl Amine," features hazard symbols, batch number, CAS: 822-43-7, and handling instructions.
    Shipping Trans-4-Methylcyclohexyl Amine should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It must be labeled according to hazardous materials regulations and handled by trained personnel. Transport should comply with local and international chemical shipping guidelines, ensuring safe handling due to its flammable and corrosive properties.
    Storage Trans-4-Methylcyclohexyl Amine should be stored in a tightly closed container in a cool, dry, well-ventilated area away from sources of ignition, heat, and incompatible materials such as strong oxidizing agents. Protect from moisture and direct sunlight. Ensure proper labeling and access to spill containment measures. Use in areas equipped with appropriate chemical safety measures, including eyewash stations and safety showers.
    Application of Trans-4-Methylcyclohexyl Amine

    Applications of Trans-4-Methylcyclohexyl Amine in Industrial Manufacturing

    Trans-4-Methylcyclohexyl Amine serves as a key intermediate in industrial synthesis, supporting the production of specialized polymers, coatings, agrochemical ingredients, and high-performance adhesives. Our vertically integrated manufacturing process ensures consistent quality for high-specification downstream applications.

    1. Polyamide Resin Production for Coatings and Films

    Polyamide manufacturers use trans-4-methylcyclohexyl amine to synthesize unique cycloaliphatic polyamides, providing enhanced mechanical strength and heat resistance for automotive coatings and flexible packaging films. The controlled addition of this amine allows precise molecular weight adjustment and improved chemical resistance, supporting both solvent-borne and water-borne systems. Each batch undergoes strict raw material verification and process monitoring to achieve low color and high UV stability required by end users in demanding industries.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006
    • ISO 9001:2015 Certified Manufacturing
    • RoHS Directive 2011/65/EU (for electronics applications)
    • Automotive OEM Performance Standards (e.g. Volkswagen TL-226)

    Typical usage ratio

    • 5–15% by mole, depending on target polyamide structure and desired mechanical properties. Ratio adjusted during prepolymer formulation to control crystallinity and processing temperature.

    Downstream process integration

    • Reacts with diacid or diester monomers during batch or continuous polycondensation. Introduced in the initial charge, blended under inert atmosphere for consistent chain extension and molecular distribution.

    Final product types

    • Flexible packaging films
    • Automotive and electronics coatings
    • Industrial flooring and pipes
    • High-barrier laminates

    2. Epoxy Curing Agent Manufacturing

    Curing agent formulators incorporate trans-4-methylcyclohexyl amine in dual-cure epoxy systems for electrical potting compounds and thermally resistant adhesives. This amine delivers controlled reactivity for room-temperature and elevated-temperature cures. Its unique cycloaliphatic backbone ensures minimal color development and low viscosity, which supports precise dosing and rapid dispersion in automated production lines. Batch records and QC analytics are maintained to guarantee amine value consistency for critical applications.

    Industry compliance standards

    • UL 94 Flammability Rating (Electrical)
    • IEC 60335-1 (Home appliance insulation)
    • GB/T 21868-2008 (Epoxy adhesive for electrical insulation)
    • ISO 14001 Environmental Management

    Typical usage ratio

    • 10–30% amine to epoxy equivalents, determined by device requirement and cure schedule. Ratios optimized through stoichiometry calculations for specific resin formulations.

    Downstream process integration

    • Premixed with epoxy resin and modifiers in high-shear mixers, then applied to electrical components or structural joints prior to thermal or atmospheric set.

    Final product types

    • PCB potting compounds
    • Industrial two-part adhesives
    • Encapsulated sensors and relays
    • Coil and motor insulation resins

    3. Isocyanate-Blocked Polyurethane Prepolymers

    Polyurethane system suppliers select trans-4-methylcyclohexyl amine as a critical chain extender and blocking agent in specialty prepolymer manufacturing. The molecular structure enables precise control of curing onset and storage stability, particularly in automotive and construction applications using one-component moisture-curable systems. The amine is added under strict temperature and nitrogen protection to prevent premature reaction, verified by FTIR and NCO titration.

    Industry compliance standards

    • ASTM D3574 (Flexible cellular materials—polyurethane foam physical properties)
    • ISO 10993-5 (Cytotoxicity for medical device components, when applicable)
    • VOC compliance per US EPA Method 24
    • REACH Annex XVII (restricted substances in polymers)

    Typical usage ratio

    • 3–10 wt% relative to isocyanate groups. The ratio is balanced based on open time, curing speed, and desired final flexibility.

    Downstream process integration

    • Mixed into isocyanate prepolymer stage, with subsequent heating to fully block reactive NCO groups. The system is later unblocked during final part molding or cure under humidity or moderate heat.

    Final product types

    • Automotive interior adhesives
    • Elastomeric sealants for construction
    • Precast concrete expansion joints
    • Assembly gaskets and foams

    4. Synthesis of Agrochemical Active Ingredients

    Agrochemical producers use trans-4-methylcyclohexyl amine as a building block in the synthesis of selective herbicides and fungicides. The amine's steric and electronic properties enable tailored molecules with high target specificity and environmental degradability. Handling and dosing follow strict chemical hygiene protocols, with traceability documented for farm-to-formula compliance. All production adheres to regulatory requirements for crop protection intermediates.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 17025 Laboratory Accreditation
    • EU Regulation No 1107/2009 (plant protection active substances)
    • Chinese GB 2763 Food Safety National MRLs (where residue registration is needed)

    Typical usage ratio

    • Varies from 0.5–2 molar equivalents in multi-step synthesis. Reaction stoichiometry fine-tuned based on yield and downstream purification demands.

    Downstream process integration

    • Introduced as a coupling partner or ring modifier during the initial synthesis or final salt formation. Monitored by in-process HPLC and GC analyses to ensure complete conversion.

    Final product types

    • Selective herbicide actives
    • Triazole and pyridine fungicides
    • Nematicide intermediates
    • Formulated agrochemical dispersions

    5. Cycloaliphatic Diamine Intermediate for Specialty Engineering Plastics

    Engineering plastics manufacturers apply trans-4-methylcyclohexyl amine in diamine synthesis for high glass transition plastics used in electronics housings and LED optics. The cycloaliphatic structure increases thermal and hydrolysis resistance, making it essential where dimensional stability and transparency are critical. Raw material is dispensed using automated gravimetric systems, with routine verification of impurity profile via GC-MS to meet end-use approvals.

    Industry compliance standards

    • UL 746C (Polymeric materials electrical properties)
    • IEC 60068 (Environmental testing of enclosures)
    • RoHS compliance for electrical goods
    • ISO 9001:2015 traceability requirements

    Typical usage ratio

    • 10–25% by weight of diamine feed in condensation reactions. Adjusted according to the required balance of mechanical strength and optical clarity.

    Downstream process integration

    • Dosed into diamine synthesis reactors prior to downstream polymerization. Incorporated under nitrogen and sampled at steady state to ensure uniformity before scale-up production.

    Final product types

    • Precision molded electronics housings
    • Optically clear LED covers
    • Automotive lamp components
    • High-transmittance engineering polymers
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    Certification & Compliance
    More Introduction

    Trans-4-Methylcyclohexyl Amine: Practical Chemistry for Modern Manufacturing

    Everyday Value from a Direct Source

    Direct manufacturing shapes the way quality and consistency reach your warehouse. At our plant, Trans-4-Methylcyclohexyl Amine—known in the industry for its moderate basicity and cyclic structure—leaves our reactors as a clear, colorless liquid with reliable purity. The compound features a single methyl group in the trans position on a cyclohexyl ring, creating subtle but important differences from its isomers. Our experience with this product runs deep, dating to our earliest developments as an amine specialist. Every shipment reflects that history of careful process control and familiarity with what modern manufacturers need from raw materials: consistent lots, predictable reactivity, and clean analytical profiles.

    The Model Behind Consistency

    Day in and day out, production teams don’t have time to wrestle with batch inconsistencies. Reactor feeds must match expectations week after week. We’ve tuned our synthesis route for the trans-isomer, putting the methyl group and the amino group on opposite sides of the cyclohexane ring. That orientation brings out better selectivity in downstream derivatizations and makes for more straightforward application in polyurethane catalyst blends or specialty pharmaceutical intermediates. We sample every drum—GC, NMR, titration—because our own experience has shown that small issues in impurity control or water content can quickly snowball in a closed-loop manufacturing campaign.

    Upstream Engineering, Downstream Peace of Mind

    The value of Trans-4-Methylcyclohexyl Amine lies in the details of its synthesis. Hydrogenation, methylation, isolation—laboratory chemists can appreciate the billions of calculations and adjustments behind each lot. We’ve seen other routes foist off-cuts of mixed isomers or higher residuals of volatile bases. Our team understands that under-processing means more work—and more trouble—down the line. By tuning catalyst beds, controlling temperature ramps, and focusing on thorough purification, we avoid trickle-down surprises that cause headaches in large-scale production.

    Differences That Shape Your Results

    Compared to N-methylcyclohexylamine or isomeric mixes, trans-4-methylcyclohexyl amine brings a precise molecular geometry. Placement of the methyl group and amino function on different sides of the ring impacts everything from solubility to reactivity. Our colleagues in performance polymers tell us this precise configuration cuts unwanted side-reactions in foam control and pigment dispersion. In adhesives, the steric bulk makes for a more tailored reactivity profile, helping to dial in cure rates and reduce yellowing over time. Years of batch-to-batch tracking confirm this: customers get higher yields and cleaner products when the source material comes with a strong analytical pedigree.

    Real-World Uses Across Industries

    Polyurethane catalysts, epoxy curing agents, and specialty pharmaceuticals—Trans-4-Methylcyclohexyl Amine finds its way into a wide spread of sectors. Polyurethane processors appreciate its effect on microcellular foam stability and its measured amine reactivity. Industrial coatings firms have told us that the rigidity of the cyclohexane ring, moderated by the methyl group, stabilizes their formulations and helps anchor crosslinker networks. For fine chemical synthesis, that combination of shape, amine basicity, and moderate volatility helps researchers build up complicated intermediates without introducing downstream purification hurdles. We’ve also watched customers incorporate it into corrosion inhibitor packages and surfactant blends, relying on our lot-consistency to keep those applications running smoothly.

    Safety, Handling, and Storage Insights

    Working with amines means taking safety seriously, as anyone from a large-scale plant operator to a bench chemist understands. We learned long ago that uncontrolled humidity can lead to colored byproducts or unwanted hazes. Our packaging aims to minimize exposure, using drums and pails lined to resist amine vapor permeation. We store all finished product under inert gas, at stable room temperature, in locked, ventilated containment. Forklift operators and warehouse staff receive hands-on training with each new batch, reviewing the unique odor of alkylcyclohexylamines and revisiting spill procedures. We don’t cut corners on traceability: every batch ticket ties back to a master record of process parameters, chilling profiles, and final purity data so that processors can track the compound across multiple production campaigns.

    Meeting Regulatory and Customer Standards

    As a core amine producer, we answer not just to customers, but to regulatory agencies inspecting everything from Hazard Communication to GHS labeling. Labels reflect actual real-time analysis—no stock declarations from months ago. Each drum or IBC is accompanied by a full COA, highlighting GC trace, water content, and appearance. Auditors visiting our plant see full compliance with REACH pre-registration for European customers, and detailed paperwork for every Asian or North American shipment. We understand that compliance and transparency limit surprises for end-users. Repeat audits from multinational chemical buyers mean our material specifications don’t budge between lots. Any changes in manufacturing procedures result in retrials and customer alerts before the first new batch leaves our site.

    No Shortcuts: From Crude to Final Product

    Consistency in Trans-4-Methylcyclohexyl Amine comes from controlling details every step of the way, starting with raw material selection. Incoming cyclohexanone streams get checked for trace aromatics and peroxides, and methylation agents are stored under strict inventory protocols. In our plant, operators know to pause production when instrument trends drift. There is no “good enough” approach—our best-performing customers have taught us that failures in purity, even at the ppm level, can derail a continuous-production campaign or sour an entire shipment of finished goods. As a manufacturer, our commitment extends past the shipping dock: we field technical requests about solubility in new solvents or analyses for trace oxidized products, and ship samples for downstream pilot runs on short lead times.

    The Human Principles of Quality Assurance

    Working on the production floor, quality does not stem from documents alone. It takes pride in the practical: tuning the distillation column to shave off the last fractions of higher-boiling isomers, or calling a halt when visual appearance strays from clear and colorless. Chemists and engineers in our facility share tips—like observing the color under multiple lights or checking the odor on a new batch before loading. That daily vigilance makes our product something customers can depend on when schedules tighten and specifications turn strict. It’s not corporate marketing; it’s the outcome of hands-on experience, logged and checked by the people who run the plant.

    Moving Materials, Supporting Customers

    We don’t just ship barrels—we support projects from pilot studies to full commercial output. Our technical services lab answers questions about reactivity in custom blends, or helps troubleshoot scale-up issues in epoxy or polyurethane manufacturing. Over the years, we’ve helped customers adjust reaction times or modify pour schedules by looking at trends in our own analytical data. When a customer requires tighter limits on a trace impurity or wants to reduce water content for a sensitive application, we tune our process and validate the improvements together. This kind of support comes from direct control of the production plant—no middlemen, no vague promises. Experience with regulators, shippers, and technical buyers means each load meets destination requirements, whether it’s shipping to a local blender or a multinational polymer plant overseas.

    Using Trans-4-Methylcyclohexyl Amine: Practical Considerations

    Handling bulk amines involves managing odor, vapor, and skin exposure—something we take seriously in our own facilities. We use closed sampling and nitrogen blanketing in our plant, and encourage customers to do the same. For process engineers worried about steel corrosion, our technical team can point to corrosion data collected across years of use, including recommended elastomer and metal compatibility. Many downstream users keep our material in bulk tanks with level gauging and vapor filters, methods born out of practical experience during our own facility expansions. Even smaller operations, blending by hand or using simple dosing setups, benefit from reliable physical properties and well-closed packaging; no more surprises from crystallized residues or hard-to-clean spills.

    Differences Compared to Other Amines

    Among available cyclohexylamines, the trans-4-methyl version earns its spot for targeted reactivity. Regular cyclohexylamine, for instance, has faster cure times but less stability in heat-aged panels. N-methyl analogues strengthen basicity but bring volatility and increased vapor hazard. From years of feedback, we see polymer and coatings engineers repeatedly return to the trans-4-methyl structure for better control over crosslink density, finer dispersion in filled systems, and a more gradual reaction profile. This isn’t theoretical advice—it’s the kind of judgment only possible after seeing outcomes over dozens of plant runs, across seasons, and in every kind of customer formula.

    Sustainability in Practice

    Manufacturers often overlook the chain of supply and waste associated with commodity amines. By maintaining batch lot integrity and minimizing off-cuts, we reduce the need for product rework and lower disposal rates. Investments in closed-loop recycling at our plant reclaim solvents and capture by-products. We actively work with customers on bulk deliveries to cut down packaging waste—nobody likes a warehouse stacked with empty drums. Our staff monitor solvent and utility use as part of day-to-day process management, not just for regulatory compliance, but because efficiency keeps costs down and customers competitive. The most sustainable solution comes from making only as much material as the customers need, and shipping with minimum footprint.

    Real World Case: Improving Customer Outcomes

    Several years ago, a long-term customer in the adhesives sector struggled with yellowing in their cured product. Looking over their spec sheets and our batch logs, we identified a small drift in methyl group isomer content coming from a change in an upstream supplier. Working together, we traced the issue and recalibrated both methylation and separation parameters on our line. Within two batches, the downstream issue—yellowing—was resolved, and the customer’s technical complaints turned into process improvements. Cases like these aren’t outliers; they reflect the back-and-forth dialogue between technical sales, lab staff, and plant operators that defines how we do things.

    Future Developments and Ongoing Improvements

    Customer requirements and regulatory standards don’t stay still. In anticipation of stricter emissions controls and new purity demands, we invest in modern reactors with better headspace controls, enhanced in-line monitoring, and analytics that extend beyond conventional GC and HPLC profiles. Feedback from coating formulators, API syntheses, or even research consortia feeds into our long-term planning—what gets measured today shapes how tomorrow’s batches perform. We keep a close eye on both European and North American regulatory changes, adapting labeling and testing standards in real time. Beyond compliance, this proactive approach puts better materials in the hands of chemists and engineers on the ground, instead of responding in crisis when laws shift.

    Building Partnerships, Not Transactions

    We see every order of Trans-4-Methylcyclohexyl Amine not as a commodity transaction, but as a step in a partnership. Whether a buyer needs a single shipment for an R&D campaign or regular loads for non-stop polymer production, the same set of plant standards and operator commitment applies. Direct channels between our staff and customer chemists mean faster troubleshooting, clearer advice, and less downtime on both sides. We’ve built relationships with researchers scaling up pilot campaigns, as well as multinational buyers standardizing across multiple plants. By owning every shipment from raw material to final delivery, we offer not just product, but practical expertise accumulated over years standing on the production floor.

    Continuous Learning, Direct Application

    No manufacturing process stays static. Every campaign teaches new lessons about equipment wear, raw material variability, or changing solvent availability. We keep a rolling log of plant changes and their effects on product quality, updating operational practices to reflect real-world outcomes. This approach keeps our Trans-4-Methylcyclohexyl Amine at the forefront of quality, with feedback cycles that move from lab bench to final blend in customer facilities. The result is a supply chain where knowledge, not accidents or guesswork, shapes every drum and every pallet.

    Practical Chemistry, Reliable Supply

    Trans-4-Methylcyclohexyl Amine doesn’t just move through spreadsheets; it arrives in research labs, blending tanks, and automation lines every week. Its reliability lets chemical processors, coatings developers, and export buyers plan further ahead, cut back on quality checks, and stay ahead in their respective markets. As a direct manufacturer, we don’t rely on vague assurances—we bring process knowledge and hands-on experience to bear, ensuring that every kilogram stands up to scrutiny and delivers on its practical promise.