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Trans-4-(4-Propylcyclohexyl)Benzonitrile

    • Product Name Trans-4-(4-Propylcyclohexyl)Benzonitrile
    • Alias 4-Propyl-4'-cyanobiphenyl
    • Einecs 403-410-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    449121

    Chemical Name Trans-4-(4-Propylcyclohexyl)Benzonitrile
    Molecular Formula C16H21N
    Molecular Weight 227.34 g/mol
    Cas Number 59246-64-1
    Appearance White to off-white crystalline powder
    Melting Point 92-95°C
    Solubility Insoluble in water; soluble in organic solvents
    Purity Typically >99%
    Density 1.02 g/cm³
    Smiles CCCCC1CCC(CC1)C2=CC=C(C#N)C=C2
    Storage Conditions Store at 2-8°C, tightly closed

    As an accredited Trans-4-(4-Propylcyclohexyl)Benzonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Trans-4-(4-Propylcyclohexyl)benzonitrile, 10g, supplied in a sealed amber glass bottle with tamper-evident cap and hazard labeling.
    Shipping Trans-4-(4-Propylcyclohexyl)benzonitrile is shipped in tightly sealed containers, protected from light, heat, and moisture. Packaging complies with chemical safety regulations, with clear labeling and documentation. It is transported via approved carriers, following all relevant local and international shipping regulations for laboratory chemicals to ensure safe and compliant delivery.
    Storage Trans-4-(4-Propylcyclohexyl)benzonitrile should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and acids. Ensure proper labeling and prevent unnecessary physical contact to maintain safety and chemical stability.
    Application of Trans-4-(4-Propylcyclohexyl)Benzonitrile

    Applications of Trans-4-(4-Propylcyclohexyl)Benzonitrile in Industrial Manufacturing

    Trans-4-(4-Propylcyclohexyl)benzonitrile serves as a critical intermediate in high-purity specialties, primarily supporting advanced display technology and precision electronics. As an original manufacturer, we supply tailored grades for demanding downstream processes in sectors where strict performance, regulatory compliance, and traceability are vital. Below are key industrial application segments, with detailed use cases and integration practices.

    1. Liquid Crystal Intermediate for Display Panel Manufacturing

    This raw material supports formulation of nematic and smectic liquid crystals in advanced LCD displays for televisions, monitors, and instrument panels. Manufacturers value its precise molecular geometry and high trans-content, contributing to enhanced mesogenic behavior and low-voltage switching. The compound directly enters the liquid crystal mixture blend after QC-incoming inspection, affecting clearing point and viscosity adjustment. Its inclusion optimizes orientation, response time, and display stability over typical operating conditions as required by major panel producers.

    Industry compliance standards

    • IEC 61747-5-2 LCD performance and reliability
    • RoHS Directive (2011/65/EU) for non-hazardous substances
    • ISO 9001:2015 for traceable QC in electronic material manufacturing
    • JEITA ED-2711 panel reliability requirements

    Typical usage ratio

    • Ranges from 2.5% to 18% in total liquid crystal material, depending on nematic or wide-temperature formulations; percentage varies with desired birefringence, dielectric anisotropy, and operating voltage.

    Downstream process integration

    • Direct blending during masterbatch composition of LC materials
    • Followed by purification, filtration, and vacuum degassing prior to injection into display cells

    Final product types

    • Thin-film transistor (TFT) LCD panels
    • Automotive instrument displays
    • High-resolution handheld device screens
    • Industrial control panel displays

    2. Precursor for High-Performance Liquid Crystal Polymers (LCPs)

    As a synthesis intermediate, this benzonitrile derivative participates in forming specialty monomers for liquid crystal polymers. These polymers provide high heat resistance and dimensional stability for microelectronic and precision connector applications. Downstream manufacturers introduce this compound in condensation reaction setups under controlled temperature and catalyst systems, ensuring repeatable product performance and targeted mechanical properties for finished goods subjected to electrical and thermal stress.

    Industry compliance standards

    • UL 94 flame-retardancy classifications for polymer parts
    • REACH Annex XVII for restricted chemicals in polymer supply chains
    • ISO 14001:2015 for environmental controls in processing
    • IEC 61249 standards for halogen-free electronics materials

    Typical usage ratio

    • Generally 8–15 mol% of monomer feed in copolymerization, dependent on melt-flow and thermal resistance targets; composition tuned according to customer application—higher loadings for high-rigidity connectors, lower for flexible substrates.

    Downstream process integration

    • Fed into high-temperature melt polymerization reactors
    • Followed by granulation, compounding, and precision pelletizing for molding operations

    Final product types

    • Microconnector housings
    • Flexible circuit substrates
    • High-performance LCP films
    • Surface-mount device carriers

    3. Functional Material Source for Electro-Optic Devices

    Producers of photonic and EO (electro-optic) devices utilize this compound in the design of advanced organic materials such as orientational order modifiers and nonlinear optical chromophores. Its rigid-cyclohexyl and propyl substitution patterns enhance stability and alignment in field-induced reorientation systems. Manufacturers introduce the raw material during early-stage organic synthesis, just ahead of the key functionalization and purification stages. Strict monitoring ensures the avoidance of side products, yielding reproducible performance in final electronic or optical assemblies.

    Industry compliance standards

    • IEC 61293 for marking electrical device components
    • RoHS and WEEE directives for device materials lifecycle
    • ISO/TS 80004 nanomaterial formulation guidance
    • Gb/t 2423.1-2017 electronics reliability (China specific)

    Typical usage ratio

    • From 0.5 mmol to 3 mmol per mole active chromophore precursor; precise value optimized for target EO modulation depth or refractive index shift.

    Downstream process integration

    • Input at the organic synthesis stage
    • Subsequent coupling or functionalization, recrystallization, and device-grade purification

    Final product types

    • Electro-optic modulator assemblies
    • Photonic integrated circuits
    • Specialized laser crystals
    • Waveguide polymers

    4. Key Intermediate for Specialty Pharmaceutical Synthesis

    In the pharmaceutical sector, research-based companies use this compound as an advanced building block to synthesize liquid crystalline drugs and proprietary drug delivery vectors. Regulatory-driven production employs validated GMP systems. Chemists introduce this benzonitrile during the key carbon–carbon or carbon–nitrogen coupling step, where purity and stereochemistry directly influence product approval. Downstream isolation, controlled crystallization, and analytical fingerprinting fulfill regulatory submissions.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • USP/NF Monograph reference for process validation traceability
    • Ph. Eur. (European Pharmacopoeia) for purity and safety
    • FDA 21 CFR Part 211 for finished pharmaceuticals

    Typical usage ratio

    • Single-digit mmol quantities per mole of finished API core; exact ratio depends on drug candidate structure and downstream transformation efficiency during route scouting or process scale-up.

    Downstream process integration

    • Incorporated in the intermediate formation or late-stage motif introgression
    • Purified, then submitted to downstream transformation or final formulation as needed

    Final product types

    • Discovery-stage liquid crystalline pharmaceuticals
    • Advanced targeted delivery systems
    • Specialized phase behavior excipients for oral-solid or injectable forms
    • Custom synthetic reference standards

    5. Additive for High-End Functional Coatings

    For electronics and sensor technology, this raw material functions as a key additive in optical and anti-static coatings. Its inclusion helps tune refractive index and film morphology in advanced coating systems, particularly for touch screens and specialty optical glass. Downstream processors add the compound after primary resin production and before final filtration, ensuring homogenous dispersion and stability throughout the film’s lifespan under varying environmental exposures.

    Industry compliance standards

    • ISO 9227 for accelerated corrosion testing on coated surfaces
    • IEC 60068-2-1/2 for environmental testing of coatings
    • EU REACH inclusions for safe chemical additives
    • RoHS Directive for coating materials on electronics

    Typical usage ratio

    • Commonly 0.8%–3.0% w/w relative to total binder solids; higher dosages possible for index modification but require compatibility study with matrix resins and substrate types.

    Downstream process integration

    • Introduced during the resin modification or pre-polymer solution
    • Followed by controlled mixing, film casting, and solvent removal

    Final product types

    • Anti-reflective optical coatings for screens
    • ESD-safe coatings on sensitive electronic housings
    • Scratch-resistant functional films
    • Sensor protective overcoats
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    Certification & Compliance
    More Introduction

    Introducing Trans-4-(4-Propylcyclohexyl)Benzonitrile: Experience From the Manufacturer's Floor

    From Our Lab to Your Process: A Closer Look at Trans-4-(4-Propylcyclohexyl)Benzonitrile

    Trans-4-(4-Propylcyclohexyl)benzonitrile stands out as a cornerstone in the family of liquid crystal intermediates. Walking through our production plant, you notice its unique, slightly viscous character almost immediately—an impact of the cyclohexyl moiety fused with the benzonitrile core and the propyl tail. Our teams have handled many aromatic nitriles and cyclohexyl compounds. This one brings a stable, predictable performance that designers of advanced displays have trusted for decades.

    The model we produce, known among industry specialists as 4-propyl-4'-cyanobicyclohexylbenzene or 4PCB, carries a specific purity profile, typically above 99.5% by HPLC, which we've refined based on rigorous QC checks at several stages. From small pilot batches to routine multi-ton production, consistency stays at the front. Our analysts often remind new technicians—the moment purity starts dipping below that threshold, color and electro-optical behavior in clients’ final mixes drift out of spec, landing screens outside the window manufacturers set. Raw material traceability, and batch-level records, matter every step along the line.

    Why Choose This Material?

    Focusing on the needs of the display sector, we saw demand increase for phase-stable, thermally robust, and low-polarity cyanobiphenyls. Trans-4-(4-Propylcyclohexyl)benzonitrile checks these. We've run side-by-side trials with its shorter and longer alkyl chain relatives and noticed distinct property shifts. When paired with the right eutectic blends, our product plays a key role in tuning clearing points and viscosity for display and temperature-sensitive electro-optical applications. Our technical process ensures that from batch to batch, mesophase behavior and dielectric anisotropy remain reliable, letting screen designers focus on clarity and responsiveness rather than requalifying their blend every time.

    In contrast to many intermediates found in the open market, our synthesis captures a high degree of trans-isomer selectivity. This gives an advantage in controlling phase transition temperatures and melting points, which downstream customers appreciate for tuning sharp switching times in LCDs. Whenever a client requests documentation or audit trails, we happily provide chromatographic histories, impurity profiles, and the lot’s actual data rather than typical published numbers.

    Specifications Informed By Real Work

    We do not treat specifications as just paperwork: they form the backbone of end-use performance. Moisture content sits below 0.05% in every registered batch, tested by coulometric Karl Fischer titration. This details the effort put in from drying tanks to inert packaging, preventing hydrolysis or degradation. For color, our QC lab tracks APHA numbers, since color bodies, even in trace amounts, build up over extensive processing. Customers have noted the off-white to faintly yellow clear liquid received from us blends seamlessly, without streaking or haze in their final product.

    By controlling isomer ratios, we hold trans:cis content at greater than 98:2, since this influences not just phase behavior but also compatibility with other blend components sold in the high-end display sector. Through controlled hydrogenation and careful column fractionation, we've optimized our method to deliver batches with sharp NMR signatures and minimal byproducts. This is one area that often separates a dedicated manufacturer from a basic repackager: careful stewardship of incoming raw materials, purification columns running on tightly monitored cycles, and real-time feedback between production and QC.

    For packing, our engineering staff dismissed cheap pails and simple drums after early lessons in trace contamination and off-gassing. We settled on new, fluorinated containers, each purged and sealed under inert nitrogen. This reduces dissolved oxygen and keeps the nitrile clear even after months in transit—no acid-catalyzed yellowing, no need for reprocessing at the customer site.

    Understanding Application and Value: Beyond the Brochure

    Trans-4-(4-Propylcyclohexyl)benzonitrile shines in liquid crystal display applications, though you'll find it in some advanced optical films and specialty electronics where phase stability and low reactivity are crucial. In our interactions with R&D chemists globally, it's clear their success depends on consistent phase transition temperatures. Even tiny changes skew alignment and refresh cycles, leaving end users with slower or more ghost-prone screens. Each year, we meet display specialists who have tried to blend in structurally similar analogs, such as trans-4-ethylcyclohexylbenzonitrile or various alkoxy derivatives, only to run into issues like lower clearing temperatures, broadened transitions, or unexpected haze in high-resolution panels.

    Its unique structure—unlike shorter-chain or bulkier cyclohexylbenzonitriles—acts as a solid compromise between molecular size and mobility. The result speaks for itself in use: fast alignment response, good light transmission, and reduced voltage requirements over time. Production managers relying on home-mixed materials or inconsistent imports face more wastage and correction cycles, which dwarfs any upfront cost benefit.

    Customers in different geographies approach us with specific compliance or environmental demands. That’s why our team follows global regulations and tests for trace solvents (such as DMF or tetrahydrofuran) that sometimes find their way into lower-quality alternatives. We support REACH and other regional requirements, which means our product ships worldwide without regulatory headaches or retroactive data requests. We do not cut corners or blend leftover stocks—each ton, regardless of the country, holds to the same strict requirements.

    Lessons Learned: Manufacturing Details Matter

    As a manufacturer, you learn quickly how minor changes echo across a complex supply chain. We’ve faced situations where a subtle slip in catalyst handling or temperature control shifts byproduct profiles, even when all other variables appear controlled. That’s why redundancy, not just in equipment but in process monitoring, sits at the core of our manufacturing philosophy. Automated controls and skilled technicians work in sync, balancing throughput with batch documentation. Every production run logs critical parameters, not just because customers ask, but because those entries let us catch trends in yield or purity before they become losses or complaints downstream.

    Raw material supply chains have become less predictable, especially with geopolitical shifts and logistics bottlenecks. We build resilience focusing on close, often contract-based relationships with trusted producers of cyclohexyl and benzonitrile precursors. Given the risks, our purchase and inventory teams stock enough material to ride out market shocks, which kept us running through recent port backlogs when other suppliers went dry.

    Years ago, we tried scaling up using off-the-shelf hydrogenation catalysts. The result, higher catalyst residues and impurity streaks, forced us to adjust our approach. Today, our proprietary purification trains involve custom-designed beds, with multiple stages including active carbon, molecular sieves, and carefully chosen solvent washes. We continue improving every aspect of post-synthesis treatment, not just for purity, but to drive down costs and cut waste at the source.

    Comparing Our Material to Other Offerings

    Some may think that a chemical like trans-4-(4-propylcyclohexyl)benzonitrile is a commodity, easily sourced from any catalog. This could not be farther from the truth for manufacturers and OEMs with demanding end-users. Over the years, we have evaluated samples from traders and importers, analyzed them by HPLC, GC-MS, and NMR, and found elevated levels of isomeric impurities, higher moisture, or trace byproducts left from bulk processing. Where sourcing companies offer standardized data sheets, we provide batch-unique analytical packets. This transparency reassures our customer’s own QC groups and helps them qualify blends for long-term supply contracts.

    A material’s apparent sameness on paper vanishes in the lab. Physical appearance, smell, viscosity, and subtle haze may not register in a cursory inspection, but show up under actual processing. An unrefined or poorly stored batch produces streaking or ghosting in final LCD panels, especially under higher temperature cycling. We pride ourselves on long-term partnerships with advanced display producers who rely on tight tolerances and feedback to keep manufacturing lines running. As they scale up, their requirements for lot-to-lot reproducibility have only tightened, an area where generic or bulk-sourced trans-4-(4-propylcyclohexyl)benzonitrile usually disappoints.

    While some users experiment with alternate cyclohexylbenzonitriles—seeking cost reductions or property tweaks—feedback suggests that products with inconsistent purities or uncontrolled isomer profiles increase rework or scrap significantly downstream. Case studies from several large Asian panel producers found that impurity spikes led directly to cycle interruptions, unwanted phase separation, or degradation of contrast ratio over prolonged use.

    Supporting End-User Innovation

    Collaboration with university labs and commercial R&D teams stands as a highlight for us as producers. Early-stage projects sometimes need custom packing, smaller scale lots, or tailored impurity analysis. Production flexibility, from kilogram R&D packs to multi-ton drum shipments, enables labs to avoid scale-up surprises. Our technical group regularly helps partners interpret phase diagrams, analyze anomalies in transition temperatures, or design stability tests, drawing on a decade of batch data and real manufacturing experience.

    One collaboration with an EU-based startup yielded a new high-contrast film, while another in Japan led to a faster-switching nematic blend. These partnerships depend on more than numbers on a data sheet. Real-time communication, verified supply consistency, and the ability to adjust supply timing without breaking the bank create an ecosystem where customers can invent faster without worrying supply chain shocks will undo their lab breakthroughs.

    We also engage with environmental stewardship groups, investing in process upgrades that cut waste, reduce emissions, and improve recyclability of process solvents. Each round of upgrades brings direct feedback into material handling and QC, which benefits not just the planet, but the wallet in the long term. Waste stream heat recovery, improved effluent processing, and cutbacks in single-use packaging have helped us reduce costs and shrink our ecological footprint year by year.

    Looking Ahead: Pathways For Consistency and Value

    As the drive toward higher resolution, faster-switching digital displays continues, trans-4-(4-propylcyclohexyl)benzonitrile will have a pivotal role. Novel LCD and OLED formulations need building blocks that perform predictably every cycle, every ambient condition. More researchers reach out to us for technical input, from blend compatibility and additive stability to thermal aging and chemical resistance. We keep our finger on the pulse by maintaining ongoing dialogues with end-users, participating in conferences, and benchmarking performance trends in the field—not just from a desktop, but through on-the-floor visits and shared troubleshooting sessions.

    Customer audits reoccur more frequently now, with greater scrutiny on supply chain transparency, documentation completeness, and ethical sourcing. We invite this, knowing the groundwork put in well before shipping builds trust and adds value that a third-party trader cannot match.

    From our standpoint, the future of components like trans-4-(4-propylcyclohexyl)benzonitrile rests on continuous attention to detail: producing clean intermediates, ensuring reliable documentation, and working closely with those pushing the envelope in display technology. Chasing title of lowest cost rarely pays off for those targeting high-performance end uses; the true rewards come from precision, honesty, and a willingness to invest in getting every detail right—batch by batch, year after year.

    Trans-4-(4-Propylcyclohexyl)benzonitrile, made not for a catalog, but for people who demand results, is our answer to that challenge. As the industry moves forward, we remain committed to doing the real work that makes advanced materials possible and, above all, reliable.